Search results for "Mesh"

showing 10 items of 885 documents

Rubinstein-Taybi syndrome (CREBBP, EP300)

2011

1.2 OMIM# of the disease180849.1.3 Name of the analyzed genes or DNA/chromosome segmentsCREBBP, EP300 (E1A binding protein p300).1.4 OMIM# of the genes600140 (CREBBP), 602700 (EP300).1.5 Mutational spectrumMainly frameshift, nonsense, splice site and missense mutations. Lessfrequently large deletions (one or more exons) and rarely balancedinversions and translocations. Mutations are heterozygous, and mosaicmutations have been described. At present, more than 100 pathogenicmutations are known for the two genes together, but mutations inEP300 are much less common (only 11 so far).

Rubinstein-Taybi SyndromeGeneticsMutationRubinstein–Taybi syndromebiologymedicine.disease_causemedicine.diseaseCREB-Binding ProteinSensitivity and SpecificityMolecular biologyFrameshift mutationExonPredictive Value of TestsMutationClinical Utility Gene CardGeneticsmedicinebiology.proteinHumansMissense mutationCREB-binding proteinEP300E1A-Associated p300 ProteinGeneGenetics (clinical)
researchProduct

Transsacral rectocele following combined neurinoma resection: A case report

2015

Highlights • Case of a combined (transsacral and laparoscopic) resection of a presacral tumour. • First described case of a transsacral rectocele two years after this procedure. • Possibility of laparoscopic defect repair of transsacral defects.

S3/4 sacral segmentmedicine.medical_specialtyDefect repairPresacral tumourmedicine.diagnostic_testbusiness.industryTumor resectionTranssacral rectoceleAbdominotranssacral tumour resectionCase ReportMagnetic resonance imaging030230 surgeryLaparoscopic mesh graft implantationResectionSurgeryBMI body-mass-index03 medical and health sciences0302 clinical medicineText mining030220 oncology & carcinogenesisMedicineSurgerybusinessMRI magnetic resonance imagingSacral segmentInternational Journal of Surgery Case Reports
researchProduct

STUDIO DEI DIFFUSORI DI SCHROEDER E MODELLAZIONE MEDIANTE DWM (DIGITAL WAVEGUIDE MESH)

2012

Sono stati trattati due differenti argomenti: lo studio della diffusione delle onde acustiche per mezzo dei diffusori di Schroeder e la modellazione acustica tramite la Digital Waveguide Mesh (DWM). E’ stato prima affrontato lo studio delle sequenze numeriche a spettro costante e il modo in cui esse vengono generate. La progettazione dei diffusori è stata studiata, partendo da una formulazione semplificata in campo lontano e variando i parametri di progetto sono stati ricavati i diagrammi polari di diffusione. In particolare, mediante i diagrammi polari in campo lontano è stata considerata la variazione della diffusione al variare della classe di sequenza (QRD, PRD, MLS), della lunghezza N …

SCHROEDERSettore ING-IND/11 - Fisica Tecnica AmbientaleDIFFUSORIDWM (DIGITAL WAVEGUIDE MESH)
researchProduct

Energetic criterion of the error evaluation in the analysis via SGBEM

2006

The Symmetric Galerkin Boundary Element Method (sGbem) is assuming more and more an effective role in the solving problems of mechanics in different fields of engineering [1]. The presence of symmetric and defined in sign algebraic operators make such Method more competitive in comparison to the formulation for collocation. The present work has as objective the improvement of the response in the process of analysis of the system where a first discretizazion has been operated, by using a strategy that allows to operate a estimate of the error. On the base of such estimate it is possible to operate a new discretizazion of the boundary through adaptive procedures.

SGBEM error criterion adaptative mesh
researchProduct

Direct Identification of Each Specific Mutation in Codon 12 and 13 of ci-ki-ras2 by SSCP Analysis

1998

We compared the SSCP behaviour of the DNA fragments containing c-ki-ras 2 wild type 12 and 13 codons or each of the 12 possible point mutated sequences in these two codons. We found that a single electrophoresis condition was sufficient to distinguish each specific mutation from the other 11 and from the wild type sequence. This observation makes it possible to identify each specific mutation directly by SSCP without any need for reamplification and sequencing.

SSCP analysisBiophysicsBiologyBiochemistryFrameshift mutationProto-Oncogene Proteins p21(ras)chemistry.chemical_compoundGene FrequencyHumansCloning MolecularRas2CodonMolecular BiologyPolymorphism Single-Stranded ConformationalSequence (medicine)GeneticsSpecific mutationCarcinomaWild typeSingle-strand conformation polymorphismDNA NeoplasmCell BiologyMolecular biologyGenes raschemistryMutationElectrophoresis Polyacrylamide GelColorectal NeoplasmsDNABiochemical and Biophysical Research Communications
researchProduct

Primitives detection by a discrete and non linear approach : application to the detection and caracterization of interest points for 3D meshes

2010

This manuscript is dedicated to the detection and caracterization of interest points for 3D meshes. First of all, we show the limitations of the curvature measure on sharp edges, the measure usually used for the analysis of meshes. Then, we present a generalization of the SUSAN operator for meshes, named SUSAN-3D. The saliency measure proposed quantify the local variation of the surface and classify directly the analysed vertices in five classes: salient, crest, flat, valley and cavity. The meshes under consideration are manifolds and can be closed or non-closed, regulars or irregulars, dense or not and noised or not. The accuracy of the SUSAN-3D operator is compared to two curvature operat…

Saliency[ MATH.MATH-GM ] Mathematics [math]/General Mathematics [math.GM]Irregular meshes[INFO.INFO-OH]Computer Science [cs]/Other [cs.OH]CaracterizationAnalyse multi-échelle[MATH.MATH-GM] Mathematics [math]/General Mathematics [math.GM]Multi-scale analysisSaillance[INFO.INFO-OH] Computer Science [cs]/Other [cs.OH]Salient pointsDétectionDetection[MATH.MATH-GM]Mathematics [math]/General Mathematics [math.GM]Maillages irréguliersCaractérisationPoints saillants[ INFO.INFO-OH ] Computer Science [cs]/Other [cs.OH]Points d'intérêtInterest points
researchProduct

Safety Evaluation of Food contact paper and board using Chemical Tests and in vitro Bioassays-The role of known and unknown substances

2010

International audience; In vitro toxicological tests has have been proposed as an approach to complement the chemical safety assessment of food contact materials, particularly those with a complex or unknown chemical composition such as paper and board. An EU 5th framework program project “BIOSAFEPAPER – Application of bioassays for safety assessment of paper and board for food contact” specially focused on the application of biotests to paper and board. The project included both chemical characterization and toxicological testing of a representative number of paper and board extracts prepared according to the proposed end use (wet, fatty and dry food contact). Among the concerns addressed …

Salmonella typhimuriumFood contact materialsMESH: WoodHealth Toxicology and MutagenesisCytotoxicity[ SDV.TOX ] Life Sciences [q-bio]/Toxicology010501 environmental sciencesmedicine.disease_causeMESH : Gas Chromatography-Mass SpectrometryToxicology01 natural sciencesMESH : Food PackagingMESH : Toxicity Testschemistry.chemical_compoundBioassayMESH: AnimalsMESH : Salmonella typhimuriumChemistryFood PackagingLife Sciences04 agricultural and veterinary sciencesGeneral MedicineWood040401 food scienceMESH : PaperFood packagingMESH : MutagensPackagingFood contact materialsAcrylamideEnvironmental chemistry[SDV.TOX]Life Sciences [q-bio]/ToxicologyToxicityBiological AssayMESH: PaperBioassayPaperMESH: Food PackagingMESH: Cell Line TumorFood Contamination[SDV.TOX.TCA]Life Sciences [q-bio]/Toxicology/Toxicology and food chainMESH: Biological Assay0404 agricultural biotechnologyCell Line TumorMESH: MutagensmedicineAnimalsHumansMutagenic compoundsMESH: Toxicity Tests0105 earth and related environmental sciencesMESH : WoodChromatographyMESH: Humansbusiness.industryMESH : Cell Line TumorMESH : HumansPublic Health Environmental and Occupational HealthMESH: Salmonella typhimuriumGeneral ChemistryMESH: Food ContaminationFood safetyMESH: Gas Chromatography-Mass SpectrometryMESH : Food ContaminationMESH : AnimalsMESH : Biological AssaybusinessGenotoxicityMutagensFood ScienceFood contaminant
researchProduct

Biologic response of inguinal hernia prosthetics: a comparative study of conventional static meshes versus 3D dynamic implants.

2015

Despite improvements in prosthetics and surgical techniques, the rate of complications following inguinal hernia repair remains high. Among these, discomfort and chronic pain have become a source of increasing concern among surgeons. Poor quality of tissue ingrowth, such as thin scar plates or shrinking scars-typical results with conventional static implants and plugs-may contribute to these adverse events. Recently, a new type of 3D dynamically responsive implant was introduced to the market. This device, designed to be placed fixation-free, seems to induce ingrowth of viable and structured tissue instead of regressive fibrotic scarring. To elucidate the differences in biologic response be…

Sampling StudieTime FactorsTime FactorProstheses and ImplantBiomedical EngineeringMedicine (miscellaneous)BioengineeringBiocompatible MaterialsHernia InguinalPolypropylenesProsthesis DesignSampling StudiesStatistics NonparametricImaging Three-DimensionalProstheseTensile StrengthMaterials TestingHumansHerniorrhaphyBiocompatible MaterialMedicine (all)Inguinal herniaImplantTissue scaffoldProstheses and ImplantsSurgical MeshBiomaterialImmunohistochemistryProsthesis FailureSettore MED/18 - Chirurgia GeneraleTissue regenerationBiomaterials; Herniorrhaphy; Implants; Inguinal hernia; Prostheses; Tissue regeneration; Tissue scaffolds; Biocompatible Materials; Hernia Inguinal; Herniorrhaphy; Humans; Imaging Three-Dimensional; Immunohistochemistry; Materials Testing; Polypropylenes; Prosthesis Design; Prosthesis Failure; Sampling Studies; Statistics Nonparametric; Tensile Strength; Time Factors; Prostheses and Implants; Surgical Mesh; Biomaterials; Biomedical Engineering; Bioengineering; Medicine (miscellaneous); Medicine (all)PolypropyleneHumanArtificial organs
researchProduct

Inguinal Hernia: Defect Obliteration with the 3D Dynamic Regenerative Scaffold Proflor™.

2021

Prosthetic inguinal hernia repair presents significant challenges. Some of these, such as mesh fixation and quality of the biologic response, are still debated among surgeons. For example, there is no strong consensus regarding a specific condition that characterizes the surgical procedure during herniorrhaphy. This issue concerns management of the hernia defect, which in conventional hernia repair with flat meshes remains patent. However, a critical analysis of typical postoperative complications after inguinal hernia repair reveals that some of these adverse events are related to patency of the hernial opening. Postoperative discomfort, pain with specific movements and even hernia recurre…

Scaffoldmedicine.medical_specialtyPain PostoperativeBiologic responsebusiness.industrymedicine.medical_treatmentProcedural approachHernia InguinalGeneral MedicineProstheses and ImplantsSurgical Meshmedicine.diseaseHernia repairGroinSurgeryMesh fixationInguinal herniaRecurrenceHernial openingmedicineHumansHerniabusinessHerniorrhaphySurgical technology international
researchProduct

Registration of arbitrary multi-view 3D acquisitions

2013

International audience; To register 3D meshes representing smooth surfaces we track the 3D digitization system using photogrammetric techniques and calibrations. We present an example by digitizing a 800 mm x 600 mm portion of a car door. To increase the tracking accuracy the 3D scanner is placed in a cubic frame of side 0.5 m covered with 78 targets. The target frame moves in a volume that is approximately 1100 mm x 850 mm x 900 mm, to digitize the area of interest. Using four cameras this target frame is tracked with of an accuracy of 0.03 mm spatially and 0.180 mrad angularly. A registration accuracy between 0.1 mm and 2 mm is reached. This method can be used for the registration of mesh…

Scanner[ INFO.INFO-TS ] Computer Science [cs]/Signal and Image ProcessingGeneral Computer Science[INFO.INFO-TS] Computer Science [cs]/Signal and Image ProcessingComputer science[ SPI.SIGNAL ] Engineering Sciences [physics]/Signal and Image processing02 engineering and technologyTracking (particle physics)01 natural sciences010309 optics[INFO.INFO-TS]Computer Science [cs]/Signal and Image Processing3D imagingComputer graphics (images)0103 physical sciences0202 electrical engineering electronic engineering information engineeringPolygon meshComputer visionDigitization[SPI.SIGNAL] Engineering Sciences [physics]/Signal and Image processingbusiness.industryClose-range photogrammetryTrack (disk drive)020208 electrical & electronic engineeringFrame (networking)General Engineering3D registrationPhotogrammetryMulti-view registrationArtificial intelligencebusiness[SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processingVolume (compression)Computers in Industry
researchProduct