Search results for "Mesh"
showing 10 items of 885 documents
A comparison of local parametric C0 Bézier interpolants for triangular meshes
2011
Parametric curved shape surface schemes interpolating vertices and normals of a given triangular mesh with arbitrary topology are widely used in computer graphics for gaming and real-time rendering due to their ability to effectively represent any surface of arbitrary genus. In this context, continuous curved shape surface schemes using only the information related to the triangle corresponding to the patch under construction, emerged as attractive solutions responding to the requirements of resource-limited hardware environments. In this paper we provide a unifying comparison of the local parametric C^0 curved shape schemes we are aware of, based on a reformulation of their original constr…
On the role of shock waves in galaxy cluster evolution
1998
Numerical simulations of galaxy clusters including two species -- baryonic gas and dark matter particles --are presented. Cold Dark Matter spectrum, Gaussian statistics and flat universe are assumed. The dark matter component is evolved numerically by means of a standard particle mesh method. The evolution of the baryonic component has been studied numerically by using a multidimensional (3D) hydrodynamical code based on modern high resolution shock capturing techniques. These techniques are specially designed for treating accurately complex flows in which shocks appear and interact. With this picture, the role of shock waves in the formation and evolution of rich galaxy clusters is analyze…
A flux-split algorithm applied to conservative models for multicomponent compressible flows
2003
In this paper we consider a conservative extension of the Euler equations for gas dynamics to describe a two-component compressible flow in Cartesian coordinates. It is well known that classical shock-capturing schemes applied to conservative models are oscillatory near the interface between the two gases. Several authors have addressed this problem proposing either a primitive consistent algorithm [J. Comput. Phys. 112 (1994) 31] or Lagrangian ingredients (Ghost Fluid Method by Fedkiw et al. [J. Comput. Phys. 152 (1999) 452] and [J. Comput. Phys. 169 (2001) 594]). We solve directly this conservative model by a flux-split algorithm, due to the first author (see [J. Comput. Phys. 125 (1996) …
Evaluation of Risk Parameters in Bone Regeneration Using a Customized Titanium Mesh
2019
PURPOSE The aim of the study was an evaluation of risk factors for an innovative bone regeneration technique using a customized titanium mesh that was tested in a clinical setting. MATERIALS AND METHODS This retrospective study included 65 patients with 70 grafting procedures of osseous defects of the jaws with a customized titanium mesh together with Advanced- and Injectable-Platelet-Rich Fibrin (A- and I-PRF), resorbable membranes, and bone grafting materials. Exposures of the meshes and grafting outcome were analyzed according to a novel classification as (a) punctual and (b) tooth width or complete exposure of the mesh (c). No exposure was stated as (d). RESULTS In 37% of cases, exposur…
Massive presence of insertion sequences in the genome of SOPE, the primary endosymbiont of the rice weevil Sitophilus oryzae
2008
Bacteria that establish an obligate intracellular relationship with eukaryotic hosts undergo an evolutionary genomic reductive process. Recent studies have shown an increase in the number of mobile elements in the first stage of the adaptive process towards intracellular life, although these elements are absent in ancient endosymbionts. Here, the genome of SOPE, the obligate mutualistic endosymbiont of rice weevils, was used as a model to analyze the initial events that occur after symbiotic integration. During the first phases of the SOPE genome project, four different types of insertion sequence (IS) elements, belonging to well-characterized IS families from γ-proteobacteria, were identif…
Dacarbazine-mediated upregulation of NKG2D ligands on tumor cells activates NK and CD8 T cells and restrains melanoma growth.
2013
International audience; Dacarbazine (DTIC) is a cytotoxic drug widely used for melanoma treatment. However, the putative contribution of anticancer immune responses in the efficacy of DTIC has not been evaluated. By testing how DTIC affects host immune responses to cancer in a mouse model of melanoma, we unexpectedly found that both natural killer (NK) and CD8(+) T cells were indispensable for DTIC therapeutic effect. Although DTIC did not directly affect immune cells, it triggered the upregulation of NKG2D ligands on tumor cells, leading to NK cell activation and IFNγ secretion in mice and humans. NK cell-derived IFNγ subsequently favored upregulation of major histocompatibility complex cl…
A new weighted normal-based filter for 3D mesh denoising
2018
In this paper, we propose a normal based filtering method for 3D mesh denoising. For this purpose, we compute the new triangle normal vectors by using a weighted sum of the average (smoothness) and the myriad (sharpness) filters in each neighborhood. These weights, that reflect the degree of the surface sharpness, are calculated according to the statistical distribution of the angles between the normal vectors of the triangles. The histogram of the angles between surface normal vectors is accurately fitted by the well known Cauchy distribution. Here, we justify the use of the myriad filter whose estimated value represents the optimum of the location parameter of the investigated distributio…
Congenital hypothyroidism caused by new mutations in the thyroid oxidase 2 (THOX2) gene
2006
Summary Objective Congenital primary hypothyroidism (CH) occurs in one of 4000 births and in 20% of the cases CH is due to a defect in thyroid hormonogenesis. Candidate genes were examined to determine the precise aetiology of suspected dyshormonogenesis in CH. Design The genes that code for thyroid peroxidase (TPO), pendrin (PDS), sodium iodide symporter (NIS) and thyroid oxidase 2 (THOX2) were sequenced directly from genomic DNA. Patients Two girls found to have CH in the neonatal screening programme and suspected of having thyroid dyshormonogenesis were investigated to identify their molecular defect. Results Patient A had a novel heterozygous 1 bp insertion in the THOX2 gene (ins602…
Linearizing Auditory Distance Estimates by Means of Virtual Acoustics
2008
Auditory distance estimates are not linearly related to physical distances: people tend to overestimate close physical distances, and underestimate far distances [I]. We have modeled a virtual listening environment whose objective is to provide a linear relationship between perceived and physical distance. The simulated environment consists of a trapezoidal membrane with specific absorbing properties at the boundaries. A physics-based model simulates acoustic wave propagation in this virtual space and provides auditory distance cues, namely intensity and direct-to-reverberant energy ratio. Simulations predict the linearity of the psychophysical function relating physical distance to perceiv…
The Molecular Basis of X-Linked Spondyloepiphyseal Dysplasia Tarda
2001
The X-linked form of spondyloepiphyseal dysplasia tarda (SEDL), a radiologically distinct skeletal dysplasia affecting the vertebrae and epiphyses, is caused by mutations in the SEDL gene. To characterize the molecular basis for SEDL, we have identified the spectrum of SEDL mutations in 30 of 36 unrelated cases of X-linked SEDL ascertained from different ethnic populations. Twenty-one different disease-associated mutations now have been identified throughout the SEDL gene. These include nonsense mutations in exons 4 and 5, missense mutations in exons 4 and 6, small (2–7 bp) and large (>1 kb) deletions, insertions, and putative splicing errors, with one splicing error due to a complex deleti…