Search results for "Meta-analysis."

showing 10 items of 889 documents

Discover cervical disc arthroplasty versus anterior cervical discectomy and fusion in symptomatic cervical disc diseases: A meta-analysis.

2016

OBJECTIVE:Symptomatic cervical disc disease (SCDD) is a common degenerative disease, and Discover artificial cervical disc, a new-generation nonconstrained artificial disk, has been developed and performed gradually to treat it. We performed this meta-analysis to compare the efficacy and safety between Discover cervical disc arthroplasty (DCDA) and anterior cervical discectomy and fusion (ACDF) for SCDD. METHODS:An exhaustive literature search of PubMed, EMBASE, and the Cochrane Library was conducted to identify randomized controlled trials that compared DCDA with ACDF for patients suffering SCDD. A random-effect model was used. Results were reported as standardized mean difference or risk …

MalePhysiologymedicine.medical_treatmentSensory Physiologylcsh:MedicineAnterior cervical discectomy and fusionIntervertebral Disc DegenerationCochrane LibraryOssificationlaw.invention0302 clinical medicineMathematical and Statistical TechniquesRandomized controlled triallawMedicine and Health SciencesRange of Motion Articularlcsh:ScienceIntervertebral DiscRandomized Controlled Trials as Topic030222 orthopedicsProstheticsMultidisciplinaryMiddle AgedSensory SystemsTreatment OutcomeSomatosensory SystemResearch DesignMeta-analysisPhysical SciencesCervical VertebraeFemaleBone RemodelingRange of motionIntervertebral Disc DisplacementStatistics (Mathematics)DiskectomyResearch ArticleBiotechnologyAdultmedicine.medical_specialtyDrug Research and DevelopmentClinical Research DesignSurgical and Invasive Medical ProceduresResearch and Analysis MethodsArthroplasty03 medical and health sciencesMusculoskeletal System ProceduresmedicineHumansClinical TrialsStatistical MethodsPharmacologybusiness.industrylcsh:RBiology and Life SciencesPain SensationArthroplastyRandomized Controlled TrialsSurgeryAssistive TechnologiesStrictly standardized mean differenceRelative risklcsh:QMedical Devices and EquipmentAdverse EventsClinical MedicinebusinessPhysiological Processes030217 neurology & neurosurgeryMathematicsMeta-AnalysisNeurosciencePloS one
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The prevalence and predictors of obstructive sleep apnea in major depressive disorder, bipolar disorder and schizophrenia: A systematic review and me…

2016

Background Obstructive sleep apnea (OSA) is a health hazard since it is associated with neurocognitive dysfunction and cardio-metabolic diseases. The prevalence of OSA among people with serious mental illness (SMI) is unclear. Method We searched major electronic databases from inception till 06/2015. Articles were included that reported the prevalence of OSA determined by polysomnography (PSG) or an apnea-hypopnea index (AHI) >5 events/hr, in people with major depressive disorder (MDD), bipolar disorder (BD) or schizophrenia. A random effects meta-analysis calculating the pooled prevalence of OSA and meta-regression of potential moderators were performed. Results Twelve articles were inc…

MalePredictive Value of TestPolysomnographyBody Mass Index0302 clinical medicineRisk FactorsPrevalenceBipolar disorder; Major depressive disorder; Obstructive sleep apnea; Schizophrenia; Serious mental illness; Sleep; Psychiatry and Mental Health; Clinical PsychologySerious mental illneobstructive sleep apneabipolar disorderAged 80 and overSleep Apnea Obstructivemedicine.diagnostic_testMiddle AgedSerious mental illnessObstructive sleep apnea Sleep Serious mental illness Major depressive disorder Bipolar disorder SchizophreniaClinical PsychologySchizophreniaserious mental illnessPsychiatry and Mental HealthPredictive value of testsMeta-analysisMajor depressive disorderPsychologyHumanAdultmedicine.medical_specialtyBipolar disorderPolysomnographyMajor depressive disorder03 medical and health sciencesPredictive Value of TestsInternal medicinemental disordersmedicineHumansBipolar disordersleepAgedDepressive Disorder Majormajor depressive disorderRisk Factormedicine.diseaseObstructive sleep apnea030227 psychiatryrespiratory tract diseasesObstructive sleep apneaschizophreniaPhysical therapySchizophreniaSleepBody mass index030217 neurology & neurosurgery
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Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis.

2014

Background: Toll-like receptor 4 (TLR4) is one of the best known TLR members expressed on the surface of several leukocytes and tissue cells and has a key function in detecting pathogen and danger-associated molecular patterns. The role of TLR4 in the pathophysiology of several age-related diseases is also well recognized, such as prostate cancer (PCa). TLR4 polymorphisms have been related to PCa risk, but the relationship between TLR4 genotypes and aggressive PCa risk has not been evaluated by any systematic reviews. Methods: We performed a systematic review and meta-analysis of candidate-gene and genome-wide association studies analyzing this relationship and included only white populatio…

MaleProstate cancer polymorphisms of TLR4 aggressive prostate cancer risk meta-analysisSystematic Reviewslcsh:MedicineGenome-wide association studySingle-nucleotide polymorphismBiologyResearch and Analysis MethodsBioinformaticsPolymorphism Single NucleotideProstate cancerGenotypeGeneticsCancer GeneticsmedicineHumansSettore MED/05 - Patologia ClinicaGenetic Predisposition to DiseaseStatistical Methodslcsh:ScienceGenotypingGenetic associationEvolutionary BiologyMultidisciplinarylcsh:RProstatic NeoplasmsBiology and Life SciencesResearch Assessmentmedicine.diseaseImmunity InnateToll-Like Receptor 4Systematic reviewMeta-analysisPhysical SciencesGenetic Polymorphismlcsh:QPopulation GeneticsMathematicsStatistics (Mathematics)Genome-Wide Association StudyResearch ArticleMeta-AnalysisPLoS ONE
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Association between urticaria and virus infections: A systematic review

2016

Background The association between urticaria and virus infections has rarely been reported in the literature. The lack of reported cases is probably due to the difficulty in establishing a cause-and-effect relationship. It is not possible to challenge the patient with an etiologic agent. Objective The purpose of this work was to perform a systematic review on the association between urticaria and virus infections. Methods This systematic review was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We searched for articles from January 1, 2008, through May 2015, by using two key terms related to urticaria and virus diseases, "urticaria" and…

MalePulmonary and Respiratory MedicineSerotypemedicine.medical_specialtyUrticariavirusesVirus diseasesVirusPathogenesis030207 dermatology & venereal diseases03 medical and health sciencesHerpesviridae Infections0302 clinical medicineimmune system diseasesparasitic diseasesHumansImmunology and AllergyMedicineskin and connective tissue diseasesProspective cohort studybusiness.industryUrticaria virus infectionGeneral MedicineDermatologySystematic reviewVirus Disease030228 respiratory systemVirus DiseasesMeta-analysisAcute DiseaseChronic DiseaseImmunologyFemalebusinessHumanAllergy and Asthma Proceedings
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One simple claudication question as first step in Peripheral Arterial Disease (PAD) screening: A meta-analysis of the association with reduced Ankle …

2019

Purpose and methods A meta-analysis using data from seven German population-based cohorts was performed by the German Epidemiological consortium of Peripheral Arterial Disease (GEPArD) to investigate whether one question about claudication is more efficient for PAD screening than established questionnaires. Claudication was defined on the basis of the answer to one question asking for pain in the leg during normal walking. This simple question was compared with established questionnaires, including the Edinburgh questionnaire. The associations of claudication with continuous ABI values and decreased ABI were analyzed by linear and logistic regression analysis, respectively. The results of t…

MaleQuestionnairesMedical DoctorsPhysiologyHealth Care ProvidersMedizinWalking030204 cardiovascular system & hematologyLogistic regressionVascular MedicineMathematical and Statistical TechniquesEndocrinology0302 clinical medicineSurveys and QuestionnairesEpidemiologyMedicine and Health SciencesMass ScreeningMedicineMedical Personnel030212 general & internal medicineMultidisciplinaryStatisticsQRMetaanalysisProfessionsmedicine.anatomical_structureResearch DesignMeta-analysisPhysical SciencesMedicineFemalemedicine.symptomResearch Articlemedicine.medical_specialtySilverEndocrine DisordersDeath RatesScienceResearch and Analysis MethodsSensitivity and SpecificityOddsPeripheral Arterial Disease03 medical and health sciencesSex FactorsPopulation MetricsGeneral PractitionersPhysiciansDiabetes mellitusInternal medicineDiabetes MellitusHumansAnkle Brachial IndexVascular Diseasesddc:610Statistical MethodsSurvey ResearchPopulation BiologyBiological Locomotionbusiness.industryBiology and Life SciencesOdds ratioIntermittent Claudicationmedicine.diseaseHealth CarePeripheral Vascular DiseaseMetabolic DisordersPeople and PlacesPopulation GroupingsAnklebusinessClaudicationMathematics
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The effectiveness of peer-support for people living with HIV: A systematic review and meta-analysis

2021

Background The practice of involving people living with HIV in the development and provision of healthcare has gained increasing traction. Peer-support for people living with HIV is assistance and encouragement by an individual considered equal, in taking an active role in self-management of their chronic health condition. The objective of this systematic review was to assess the effects of peer-support for people living with HIV. Methods We conducted a systematic review in accordance with international guidelines. Following systematic searches of eight databases until May 2020, two reviewers performed independent screening of studies according to preset inclusion criteria. We conducted ri…

MaleRNA virusesEpidemiologyHIV InfectionsPeer supportPathology and Laboratory MedicineMathematical and Statistical TechniquesImmunodeficiency VirusesHealth careMedicine and Health SciencesPublic and Occupational HealthRandomized Controlled Trials as TopicMultidisciplinaryVDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin sosialmedisin: 801StatisticsQRHIV diagnosis and managementMetaanalysisResearch AssessmentVaccination and ImmunizationPeer reviewTreatment OutcomeAnti-Retroviral AgentsVDP::Medisinske Fag: 700::Helsefag: 800Medical MicrobiologyMeta-analysisViral PathogensVirusesPhysical SciencesMedicineFemalePathogensResearch Articlemedicine.medical_specialtyDrug Research and DevelopmentSystematic ReviewsScienceImmunologyMEDLINEAntiretroviral TherapyResearch and Analysis MethodsMicrobiologyPeer GroupQuality of life (healthcare)Antiviral TherapyRetrovirusesMental Health and PsychiatrymedicineHumansClinical TrialsStatistical MethodsMicrobial PathogensPharmacologybusiness.industryLentivirusOrganismsSocial SupportBiology and Life SciencesHIVOdds ratioRandomized Controlled TrialsDiagnostic medicineFamily medicineRelative riskMedical Risk FactorsHIV-1Preventive MedicineClinical MedicineVDP::Medical disciplines: 700::Health sciences: 800::Community medicine Social medicine: 801businessMathematics
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Interest in meta-research in geriatric medicine: a survey of members of the European Geriatric Medicine Society

2020

To know the knowledge of the EuGMS members regarding meta-research, especially systematic reviews and meta-analyses. Interest in systematic reviews and meta-analyses is high and there is a demand for education on these topics in relation to geriatric medicine. We need more resources in the EuGMS for education for meta-research tailored for geriatric medicine. There has been an exponential increase in meta-research, especially in the branch dealing with systematic reviews [SRs] and meta-analyses [MAs]. However, the knowledge regarding these topics in geriatric medicine is still poorly explored. We therefore undertook a survey of the current knowledge and needs in meta-research in geriatrics.…

MaleResearch Reportmedicine.medical_specialty2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)EuGMSSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)meta-research03 medical and health sciences0302 clinical medicineMeta researchGermanySurveys and QuestionnairesMedicine and Health SciencesmedicineMeta-analysis Systematic review Questionnaire EuGMSHumanssurvey030212 general & internal medicineAgedGeriatricsa survey of members of the European Geriatric Medicine Society- EUROPEAN GERIATRIC MEDICINE 2020 [Veronese N. Torbahn G. Demurtas J. Beaudart C. SOYSAL P. Marengoni A. Shenkin S. D. Petrovic M. Sieber C. C. Cherubini A. et al. -Interest in meta-research in geriatric medicine]030214 geriatricsgeriatric medicinebusiness.industryQuestionnaireEuropean Geriatric Medicine SocietyMiddle AgedClinical PracticeMeta-analysisSystematic reviewGeriatricsFamily medicineMeta-analysisEuGMS; Meta-analysis; Questionnaire; Systematic reviewSystematic reviewEuGMS; Meta-analysis; Questionnaire; Systematic review; Aged; Female; Germany; Humans; Male; Middle Aged; Research Report; Societies; Surveys and Questionnaires; GeriatricsFemalebusinessSocieties
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Effectiveness of constraint-induced movement therapy on activity and participation after stroke: a systematic review and meta-analysis of randomized …

2011

Objective: To examine the effect of constraint-induced movement therapy and modified constraint-induced movement therapy on activity and participation of patients with stroke (i.e. the effect of different treatment durations and frequency) by reviewing the results of randomized controlled trials. Data sources: A systematic literature search was conducted in MEDLINE, CINAHL, EMBASE, PEDro, OTSeeker, CENTRAL and by manual search. Review methods: Randomized controlled trials for patients over 18 years old with stroke and published in Finnish, Swedish, English or German were included. Studies were collected up to the first week in May 2011. The evidence was high, moderate, low or no evidence a…

MaleRestraint Physicalmedicine.medical_specialtyActivities of daily livingMEDLINEHemiplegiaPhysical Therapy Sports Therapy and RehabilitationCINAHLRisk Assessmentlaw.inventionUpper ExtremityPhysical medicine and rehabilitationRandomized controlled triallawActivities of Daily LivingHumansMedicinePatient participationta315StrokeFinlandta515Randomized Controlled Trials as Topicbusiness.industryRehabilitationStroke RehabilitationRecovery of FunctionPrognosismedicine.diseaseSelf CareStrokeConstraint-induced movement therapyTreatment OutcomeMeta-analysisPhysical therapyExercise Movement TechniquesFemalePatient ParticipationbusinessCLINICAL REHABILITATION
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Consumption of Fish and ω-3 Fatty Acids and Cancer Risk: An Umbrella Review of Meta-Analyses of Observational Studies

2020

Multiple studies have suggested that ω-3 fatty acid intake may have a protective effect on cancer risk; however, its true association with cancer risk remains controversial. We performed an umbrella review of meta-analyses to summarize and evaluate the evidence for the association between ω-3 fatty acid intake and cancer outcomes. We searched PubMed, Embase, and the Cochrane Database of Systematic Reviews from inception to December 1, 2018. We included meta-analyses of observational studies that examined associations between intake of fish or ω-3 fatty acid and cancer risk (gastrointestinal, liver, breast, gynecologic, prostate, brain, lung, and skin) and determined the level of evidence of…

MaleRiskOncologymedicine.medical_specialty[SDV]Life Sciences [q-bio]BFMedicine (miscellaneous)ReviewCohort Studies03 medical and health sciencesProstate cancer0302 clinical medicineBreast cancerω-3 fatty acidMeta-Analysis as TopicNeoplasmsInternal medicineFatty Acids Omega-3medicineAnimalsHumanscancer030212 general & internal medicineω-3 fatty acid fish cancer umbrella review meta-analysischemistry.chemical_classificationfishNutrition and Dieteticsumbrella reviewbusiness.industryEndometrial cancerFishesFatty acidCancermedicine.diseaseR13. Good healthmeta-analysisObservational Studies as TopicchemistryCase-Control Studies030220 oncology & carcinogenesisMeta-analysisFemaleSkin cancerbusinessLiver cancerFood Science
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The REALIST (REsiduAl risk, LIpids and Standard Therapies) study: an analysis of residual risk attributable to lipid profile in acute coronary syndro…

2010

The R3i Foundation (Residual Risk Reduction Initiative), an independent, multinational and academic organization, is conducting the REALIST (Residual Risk, Lipids and Standard Therapies) study in 40 centers in different countries. This is a retrospective epidemiological study, designed to provide new data on the residual risk of major coronary events attributable to lipid abnormalities in patients receiving the current standard treatment. The initial results are expected in mid 2010, and the overall results at the end of 2010.

MaleRiskmedicine.medical_specialtyAcute coronary syndromeInternational CooperationRisk AssessmentMedical RecordsMeta-Analysis as TopicRecurrenceInternal medicinemedicineHumansAcute Coronary SyndromeAgedDyslipidemiasRetrospective StudiesAged 80 and overHypertriglyceridemiamedicine.diagnostic_testbusiness.industryPatient SelectionStandard treatmentCholesterol HDLCase-control studyRetrospective cohort studyCholesterol LDLMiddle AgedAtherosclerosismedicine.diseaseLipidsSurgeryResidual riskCardiovascular DiseasesCase-Control StudiesFemaleHydroxymethylglutaryl-CoA Reductase InhibitorsLipid profileRisk assessmentbusinessDyslipidemiaEndocrinología y Nutrición (English Edition)
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