Search results for "Mg"
showing 10 items of 492 documents
Antagonist mechanical contribution to resultant maximal torque at the ankle joint in young and older men.
2007
Abstract A recorded muscular torque at one joint is a resultant torque corresponding to the participation of both agonist and antagonist muscles. This study aimed to examine the effect of aging on the mechanical contributions of both plantar- and dorsi-flexors to the resultant maximal voluntary contraction (MVC) torques exerted at the ankle joint, in dorsi-flexion (DF) and plantar-flexion (PF). The estimation of isometric agonist and antagonist torques by means of an EMG biofeedback technique was made with nine young (mean age 24 years) and nine older (mean age 80 years) men. While there was a non-significant age-related decline in the measured resultant DF MVC torque (−15%; p =0.06), there…
Systemic administration of D-penicillamine prevents the locomotor activation after intra-VTA ethanol administration in rats.
2010
Although recently published studies seem to confirm the important role displayed by acetaldehyde (ACH), the main metabolite of ethanol, in the behavioral effects of ethanol, the origin of ACH is still a matter of debate. While some authors confer more importance to the central (brain metabolism) origin of ACH, others indicate that the hepatic origin could be more relevant. In this study we have addressed this topic using an experimental approach that combines local microinjections of ethanol into the ventral tegmental area (VTA) (which guarantees the brain origin of the ACH) to induce motor activation in rats together with systemic administration (i.p.) of several doses (0, 12.5, 25 and 50 …
Products of snowflaked Euclidean lines are not minimal for looking down
2017
We show that products of snowflaked Euclidean lines are not minimal for looking down. This question was raised in Fractured fractals and broken dreams, Problem 11.17, by David and Semmes. The proof uses arguments developed by Le Donne, Li and Rajala to prove that the Heisenberg group is not minimal for looking down. By a method of shortcuts, we define a new distance $d$ such that the product of snowflaked Euclidean lines looks down on $(\mathbb R^N,d)$, but not vice versa.
sULLE ANGIODISPLASIE VENOSE DEL SISTEMA GIUGULARE ESTERNO NELL'INFANZIA
1978
Gli Autori descrivono un caso di angiodisplasia venosa del collo (il cosiddetto venoma) per contribuire alla clinica e terapia dell'affezione.
Governare il Mezzogiorno. Gli alleati e l'occupazione/liberazione del Sud (1943-1945)
2015
In winter 1943 the United Stated and Britain planned the invasion of Axis-held Europe and decided to invade Sicily. A Military Government (Amgot) – which would be a model for the future Allied administration in Europe – was set in order to administrate the occupied territories. While the Allied propaganda presented the invasion of Italy as a «liberation» from the Axis yoke, when in summer 1943 the Allied troops landed in Sicily, Italy was actually treated as a fully-fledged enemy country. When the Amgot became operative, the contradictory role of the Allies in the occupation emerged clearly. The aim of this article is to examine the complex aspects of this military occupation in Sicily an…
Statin-induced autoimmune myositis: a proposal of an “experience-based” diagnostic algorithm from the analysis of 69 patients
2023
AbstractStatin-induced autoimmune myositis (SIAM) represents a rare clinical entity that can be triggered by prolonged statin treatment. Its pathogenetic substrate consists of an autoimmune-mediated mechanism, evidenced by the detection of antibodies directed against the 3-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR Ab), the target enzyme of statin therapies. To facilitate the diagnosis of nuanced SIAM clinical cases, the present study proposes an “experience-based” diagnostic algorithm for SIAM. We have analyzed the clinical data of 69 patients diagnosed with SIAM. Sixty-seven patients have been collected from the 55 available and complete case records regarding SIAM in the l…
Cholesterol in Alzheimer’s Disease and other Amyloidogenic Disorders
2010
The complex association of cholesterol metabolism and Alzheimer’s disease is presented in depth, including the possible benefits to be gained from cholesterol-lowering statin therapy. Then follows a survey of the role of neuronal membrane cholesterol in Aβ pore formation and Aβ fibrillogenesis, together with the link with membrane raft domains and gangliosides. The contribution of structural studies to Aβ fibrillogenesis, using TEM and AFM, is given some emphasis. The role of apolipoprotein E and its isoforms, in particular ApoE4, in cholesterol and Aβ binding is presented, in relation to genetic risk factors for Alzheimer’s disease. Increasing evidence suggests that cholesterol oxidation p…
A note on topological dimension, Hausdorff measure, and rectifiability
2020
The purpose of this note is to record a consequence, for general metric spaces, of a recent result of David Bate. We prove the following fact: Let $X$ be a compact metric space of topological dimension $n$. Suppose that the $n$-dimensional Hausdorff measure of $X$, $\mathcal H^n(X)$, is finite. Suppose further that the lower n-density of the measure $\mathcal H^n$ is positive, $\mathcal H^n$-almost everywhere in $X$. Then $X$ contains an $n$-rectifiable subset of positive $\mathcal H^n$-measure. Moreover, the assumption on the lower density is unnecessary if one uses recently announced results of Cs\"ornyei-Jones.
Singular integrals on regular curves in the Heisenberg group
2019
Let $\mathbb{H}$ be the first Heisenberg group, and let $k \in C^{\infty}(\mathbb{H} \, \setminus \, \{0\})$ be a kernel which is either odd or horizontally odd, and satisfies $$|\nabla_{\mathbb{H}}^{n}k(p)| \leq C_{n}\|p\|^{-1 - n}, \qquad p \in \mathbb{H} \, \setminus \, \{0\}, \, n \geq 0.$$ The simplest examples include certain Riesz-type kernels first considered by Chousionis and Mattila, and the horizontally odd kernel $k(p) = \nabla_{\mathbb{H}} \log \|p\|$. We prove that convolution with $k$, as above, yields an $L^{2}$-bounded operator on regular curves in $\mathbb{H}$. This extends a theorem of G. David to the Heisenberg group. As a corollary of our main result, we infer that all …
Quasisymmetric spheres over Jordan domains
2015
Let $\Omega$ be a planar Jordan domain. We consider double-dome-like surfaces $\Sigma$ defined by graphs of functions of $dist( \cdot ,\partial \Omega)$ over $\Omega$. The goal is to find the right conditions on the geometry of the base $\Omega$ and the growth of the height so that $\Sigma$ is a quasisphere, or quasisymmetric to $\mathbb{S}^2$. An internal uniform chord-arc condition on the constant distance sets to $\partial \Omega$, coupled with a mild growth condition on the height, gives a close-to-sharp answer. Our method also produces new examples of quasispheres in $\mathbb{R}^n$, for any $n\ge 3$.