Search results for "Microfiber"

Enhanced adhesion and in situ photothermal ablation of cancer cells in surface-functionalized electrospun microfiber scaffold with graphene oxide

2017

The physicochemical characteristics of a biomaterial surface highly affect the interaction with living cells. Recently, much attention has been focused on the adhesion properties of functional biomaterials toward cancer cells, since is expected to control metastatic spread of a tumor, which is related to good probability containing the progression of disease burden. Here, we designed an implantable poly(caprolactone)-based electrospun microfiber scaffold, henceforth PCLMF-GO, to simultaneously capture and kill cancer cells by tuning physicochemical features of the hybrid surface through nitrogen plasma activation and hetero-phase graphene oxide (GO) covalent functionalization. The surface i…

Confident methods for the evaluation of the hydrogen content in nanoporous carbon microfibers

2012

Abstract Nanoporous carbon microfibers were grown by chemical vapor deposition in the vapor-liquid solid mode using different fluid hydrocarbons as precursors in different proportions. The as-grown samples were further treated in argon and hydrogen atmospheres at different pressure conditions and annealed at several temperatures in order to deduce the best conditions for the incorporation and re-incorporation of hydrogen into the microfibers through the nanopores. Since there are some discrepancies in the results on the hydrogen content obtained under vacuum conditions, in this work, we have measured the hydrogen content in the microfibers using several analytical methods in ambient conditi…

BIO-Bragg gratings: structured molecular networks for on-fiber bioanalysis

2021

The research on photonic biosensors is a scientific hot topic at the moment, with a significant potential impact on industry and medicine. Label-free, miniaturized, inexpensive and low-loss biosensors are developed based on optical fiber technology. Our approach is based on a Bio-Bragg-Grating (BBG) patterned on the surface of a microfiber. We present the design, fabrication and proof of concept of our device, as well as its multiplexing and tunability perspectives [1] .

Production of hyaluronic acid derivative microfibers with controlled dimension as potential drug delivery system

2015

BIO Bragg gratings on microfibers for label-free biosensing

2021

[EN] Discovering nanoscale phenomena to sense biorecognition events introduces new perspectives to exploit nano science and nanotechnology for bioanalytical purposes. Here we present Bio Bragg Gratings (BBGs), a novel biosensing approach that consists of diffractive structures of protein bioreceptors patterned on the surface of optical waveguides, and tailored to transduce the magnitude of biorecognition assays into the intensity of single peaks in the reflection spectrum. This work addresses the design, fabrication, and optimization of this system by both theoretical and experimental studies to explore the fundamental physicochemical parameters involved. Functional biomolecular gratings ar…

Microfluidic Fabrication of Physically Assembled Nanogels and Micrometric Fibers by Using a Hyaluronic Acid Derivative

2017

The employ of a hyaluronic acid (HA) derivative, bearing octadecyl (C18) and ethylenediamine (EDA) groups, for microfluidic fabrication of nanogels and microfibers is reported in this study. Two HA-EDA-C18 derivatives (125 and 320 kDa) having ionic strength sensitive properties are synthesized and characterized. The control of the rheological properties of HA-EDA-C18 aqueous dispersions by formation of inclusion complexes with hydroxypropyl-β-cyclodextrins (HPCD) is described. Reversibility of C18/HPCD complexation and physical crosslinking is detected in media with different ionic strength through oscillation frequency tests. HA-EDA-C18 125 kDa is employed for nanogel fabrication. Control …

Microfluidic production of hyaluronic acid derivative microfibers to control drug release

2016

"Available online 4 July 2016"

Ingestion of plastic and non-plastic microfibers by farmed gilthead sea bream (Sparus aurata) and common carp (Cyprinus carpio) at different life sta…

2021

Environmental pollution by plastic particles is of major global concern, as a potential threat to aquatic organisms and ecosystems. The accumulation of microplastics in freshwater and marine environments has strong ecological implications due to their long persistence, potential toxicity, and ability to adsorb other pollutants, acting as vectors of pathogens. Nevertheless, while the number of studies on the presence of microplastics in the wild fish increased, less attention has been paid to the farmed fish species. Here, we investigated the occurrence of microparticles in the digestive tracts of Sparus aurata and Cyprinus carpio at different life stages and reared by an intensive and semi-…

Observation of a nonlinear microfiber resonator

2008

Measurements of the intensity transfer function of a silica microfiber resonator are shown to follow a wide variety of hysteresis cycles, depending on the cavity detuning and the scanning frequency of the range of input powers. We attribute these observations to a nonlinear phase shift of thermal origin and provide a simple model that reproduces well our measurements. The response time is found to be around 0.6 ms.

Potentialities of glass air-clad micro- and nanofibers for nonlinear optics

2010

Micro- and nanofibers constitute an attractive platform for testing nonlinear devices with millimeter size in a simple and flexible fashion, with potential applications in ultra-fast all-optical communications. In this article, we present challenges that must be addressed and targets that can be reached using such a platform. We describe a tunable laser source capable of delivering pulses with a kilowatt peak power and a sub-0.1-nm linewidth that is specially designed for the study of resonant devices such as the nonlinear loop resonator. Experimental and simulation results are presented for silica microfiber based nonlinear devices. The prospect of developing hybrid devices combining highl…