Search results for "Microsatellite"

showing 10 items of 425 documents

Isolation and characterization of 10 highly polymorphic di- and trinucleotide microsatellite markers in the mayfly Ameletus inopinatus (Ephemeroptera…

2008

We describe the isolation of ten polymorphic microsatellite loci from the mayfly Ameletus inopinatus. Loci had di- or trinucleotide repeat motifs and were highly variable with three to 17 alleles (mean = 7.15). Observed heterozygosity ranged from 0.143 to 0.905. One locus (Ami_202) showed significant deviation from Hardy–Weinberg equilibrium in one population, but no evidence for null alleles. One locus (Ami_73) was significantly linked with three other loci. The remaining nine loci should prove highly informative for population genetic studies.

Geneticseducation.field_of_studyPopulationLocus (genetics)Biologybiology.organism_classificationNull alleleLoss of heterozygosityMayflyGeneticsMicrosatelliteeducationTrinucleotide repeat expansionMicrosatellite enrichmentEcology Evolution Behavior and SystematicsBiotechnologyMolecular ecology resources
researchProduct

A large panel of novel microsatellite markers for the bank vole (Myodes glareolus)

2008

We describe a set of 66 highly polymorphic microsatellite loci isolated from the bank vole, Myodes (Clethrionomys) glareolus. These microsatellites were characterized for a long-term study on periodically fluctuating density of the bank vole population in Central Finland. We detected six to 38 alleles per locus in the population sampled at two different density phases, and the levels of observed and expected heterozygosities varied between 0.17 and 1.00, and between 0.72 and 0.95, respectively. This microsatellite panel serves as an informative tool for population and molecular genetic studies.

Geneticseducation.field_of_studybiologyPopulationMyodes glareolusZoologyLocus (genetics)biology.organism_classificationBank voleGeneticsMicrosatelliteAlleleeducationEcology Evolution Behavior and SystematicsBiotechnologyMolecular Ecology Resources
researchProduct

Isolation and characterization of 11 polymorphic trinucleotide microsatellite markers in the stonefly Arcynopteryx compacta (Plecoptera: Perlodidae).

2011

We describe the isolation of 11 polymorphic trinucleotide microsatellite loci from the stonefly Arcynopteryx compacta. Loci were highly variable with 3 to 14 alleles (mean = 6.45). Observed heterozygosity ranged from 0 to 0.867. Seven loci showed significant deviation from Hardy–Weinberg equilibrium across both populations. There was no evidence for null alleles, and thus, Hardy–Weinberg departures could have resulted from genetic structure between populations or subpopulations. No linkage between loci was found. The 11 loci should prove highly informative for population genetic studies.

Geneticseducation.field_of_studybiologyPopulationbiology.organism_classificationNull alleleLoss of heterozygosityPerlodidaeGenetic structureGeneticsMicrosatelliteAlleleeducationMicrosatellite enrichmentEcology Evolution Behavior and SystematicsBiotechnologyMolecular ecology resources
researchProduct

Y-chromosomal STR haplotypes in Sicily

2006

Eight Y-chromosomal short tandem repeats (STRs)-DYS19, DYS389-I, DYS389-II, DYS390, DYS391, DYS392, DYS393 and DYS385 - were typed in a population sample (n = 255) of unrelated Sicilian males from nine different towns on the main island and from the island of Pantelleria. (c) 2005 Elsevier Ireland Ltd. All rights reserved.

GeneticshaplotypeChromosomes Human YPopulation sampleshort tandem repeatHaplotypePopulation geneticsY-chromosome; Short tandem repeats; Haplotype; SicilyBiologyY chromosomeDNA Fingerprintinglanguage.human_languageWhite PeoplePathology and Forensic MedicineGenetics PopulationShort tandem repeatsHaplotypesTandem Repeat SequenceslanguageMicrosatelliteHumansLawSicilianY-chromosomeSicily
researchProduct

Survival relative to new and ancestral host plants, phytoplasma infection, and genetic constitution in host races of a polyphagous insect disease vec…

2014

Dissemination of vectorborne diseases depends strongly on the vector's host range and the pathogen's reservoir range. Because vectors interact with pathogens, the direction and strength of a vector's host shift is vital for understanding epidemiology and is embedded in the framework of ecological specialization. This study investigates survival in host-race evolution of a polyphagous insect disease vector, Hyalesthes obsoletus, whether survival is related to the direction of the host shift (from field bindweed to stinging nettle), the interaction with plant-specific strains of obligate vectored pathogens/symbionts (stolbur phytoplasma), and whether survival is related to genetic differentia…

Geneticsstolbur phytoplasmaEcologyObligateHost (biology)tritrophic interactionAssortative matingBiologybiology.organism_classificationmicrosatelliteshost-race evolutionRace (biology)PhytoplasmaGene–behavior interactionVector (epidemiology)Hyalesthes obsoletusPathogenEcology Evolution Behavior and SystematicsOriginal ResearchNature and Landscape ConservationMaladaptationEcology and Evolution
researchProduct

Simultaneous Aurora-A/STK15 overexpression and centrosome amplification induce chromosomal instability in tumour cells with a MIN phenotype

2007

Abstract Background Genetic instability is a hallmark of tumours and preneoplastic lesions. The predominant form of genome instability in human cancer is chromosome instability (CIN). CIN is characterized by chromosomal aberrations, gains or losses of whole chromosomes (aneuploidy), and it is often associated with centrosome amplification. Centrosomes control cell division by forming a bipolar mitotic spindle and play an essential role in the maintenance of chromosomal stability. However, whether centrosome amplification could directly cause aneuploidy is not fully established. Also, alterations in genes required for mitotic progression could be involved in CIN. A major candidate is represe…

Genome instabilityCancer ResearchCellular differentiationAneuploidyApoptosisCell CommunicationSpindle ApparatusBiologyProtein Serine-Threonine Kinaseslcsh:RC254-282Aurora KinasesChromosome instabilityChromosomal InstabilitymedicineTumor Cells CulturedGeneticsHumansRNA Small InterferingMitosisIn Situ Hybridization FluorescenceAurora Kinase ACentrosomePloidiesReverse Transcriptase Polymerase Chain ReactionAurora-A centrosomes amplification aneuploidyCell Differentiationlcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensmedicine.diseaseAneuploidyCell biologySpindle apparatusUp-RegulationSettore BIO/18 - GeneticaCell Transformation NeoplasticPhenotypeMicroscopy FluorescenceOncologyCentrosomeColonic NeoplasmsEctopic expressionMicrosatellite InstabilityResearch ArticleBMC Cancer
researchProduct

Patterns of genomic instability in gastric cancer: clinical implications and perspectives

2007

In gastric cancer (GC) the loss of genomic stability represents a key molecular step that occurs early in the carcinogenesis process and creates a permissive environment for the accumulation of genetic and epigenetic alterations in tumor suppressor genes and oncogenes. It is widely accepted that GC can follow at least two major genomic instability pathways, microsatellite instability (MSI) and chromosome instability (CIN). MSI is responsible for a well-defined subset of GCs. CIN represents a more common pathway comprising heterogeneous subsets of GC. In addition to MSI and CIN, the CpG islands methylator phenotype (CIMP) plays an important role in gastric carcinogenesis. CIMP may lead to th…

Genome instabilitybusiness.industrygastric cancer genomic instability microsatellite instability (MSI) chromosomal instability (CIN) CpG island methylator phenotype (CIMP) clinical implicationsMicrosatellite instabilityHematologyDNA Methylationmedicine.diseasemedicine.disease_causedigestive system diseasesDNA demethylationOncologyCpG siteStomach NeoplasmsChromosomal InstabilityChromosome instabilityDNA methylationmedicineCancer researchHumansCpG IslandsMicrosatellite InstabilityEpigeneticsbusinessCarcinogenesisneoplasms
researchProduct

Historical and biological determinants of genetic diversity in the highly endemic triploid sea lavender Limonium dufourii (Plumbaginaceae)

2007

14 páginas, 5 figuras, 2 tablas.

GenotypePopulationBiologyPlant conservationGenetic diversityEvolution MolecularCritically endangeredPlumbaginaceaeHalophytesAlloploidyGenetic variationGeneticsAlleleMicrosatelliteseducationAllelesEcology Evolution Behavior and Systematicseducation.field_of_studyGenetic diversityGeographyEcologyGenetic VariationSequence Analysis DNASpainGenetic markerEvolutionary biologyGenetic structureHybridization GeneticMicrosatelliteApomixisGenome PlantMicrosatellite RepeatsMolecular Ecology
researchProduct

Effects of Large-Scale Releases on the Genetic Structure of Red Sea Bream (Pagrus major, Temminck et Schlegel) Populations in Japan.

2014

Large-scale hatchery releases are carried out for many marine fish species worldwide; nevertheless, the long-term effects of this practice on the genetic structure of natural populations remains unclear. The lack of knowledge is especially evident when independent stock enhancement programs are conducted simultaneously on the same species at different geographical locations, as occurs with red sea bream (Pagrus major, Temminck et Schlegel) in Japan. In this study, we examined the putative effects of intensive offspring releases on the genetic structure of red sea bream populations along the Japanese archipelago by genotyping 848 fish at fifteen microsatellite loci. Our results suggests weak…

GenotypeSciencePopulationFisheriesPopulation geneticsAquacultureBiologyPagrus majorJapanAquacultureAnimalseducationeducation.field_of_studygeographyMultidisciplinarygeography.geographical_feature_categorybusiness.industryEcologyQRbiology.organism_classificationSea BreamHatcheryGenetic divergenceGenetics PopulationArchipelagoGenetic structureMedicinebusinessMicrosatellite RepeatsResearch ArticlePLoS ONE
researchProduct

Genetic diversity and relationships among Italian and foreign almond germplasm as revealed by microsatellite markers

2013

Abstract Italian germplasm is characterized by a wide diversity rapidly developed determining a massive genetic pool of cultivars in several growing areas. On the whole, regions of southern Italy, and in particular Sicily, were considered as one of the main trade routes along which almond was spread throughout the shores of the Mediterranean Sea. In this work, 9 SSR markers have been used to analyze 113 almond cultivars and accessions coming from ex-situ conservation, including most of almond genotypes spread in Sicily and Apulia and foreign cultivars from Mediterranean, American and Australian areas in order to determine the level of genetic diversity within Italian genotypes and elucidate…

GermplasmCitrusGenotypingGenetic diversityeducation.field_of_studyPhylogenetic treeEcologyPopulationfood and beveragesHorticultureBiologySSRSettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeCitrus; Genotyping; SSRCultivated almondGenetic variationBotanyMicrosatelliteGenetic variationGene poolCultivareducationScientia Horticulturae
researchProduct