Search results for "Migration"

showing 10 items of 1709 documents

miR-205-5p-mediated downregulation of ErbB/HER receptors in breast cancer stem cells results in targeted therapy resistance

2015

AbstractThe ErbB tyrosine kinase receptor family has been shown to have an important role in tumorigenesis, and the expression of its receptor members is frequently deregulated in many types of solid tumors. Various drugs targeting these receptors have been approved for cancer treatment. Particularly, in breast cancer, anti-Her2/EGFR molecules represent the standard therapy for Her2-positive malignancies. However, in a number of cases, the tumor relapses or progresses thus suggesting that not all cancer cells have been targeted. One possibility is that a subset of cells capable of regenerating the tumor, such as cancer stem cells (CSCs), may not respond to these therapeutic agents. Accumula…

P63cancer stem cellsCancer ResearchReceptor ErbB-2oncogenesmedicine.medical_treatmentmedicine.disease_causeTargeted therapyERBB3Molecular Targeted TherapyDEATHErbB ReceptorsGene Expression Regulation NeoplasticNeoplastic Stem CellsFemaleOriginal Articlemedicine.drugCARCINOMAMIGRATIONCancer Stem Cells; Breast CancerImmunologyBreast NeoplasmsCancer Stem CellMIR-205miR-205-5pBiologyLapatinibcancer treatmentNOCellular and Molecular Neurosciencebreast cancerBreast cancerErbBCancer stem cellCell Line TumormedicineHumansSUPPRESSIONCell ProliferationMESENCHYMAL TRANSITIONtumorigenesis cancer treatment cancer stem cells miR-205-5p oncogenes breast cancerMICRORNA EXPRESSIONTumor Suppressor ProteinsLapatinibCell BiologyTrastuzumabmedicine.diseaseGENEMicroRNAstumorigenesisDrug Resistance NeoplasmCancer cellQuinazolinesCancer researchNeoplasm Recurrence LocalCarcinogenesisTranscription FactorsCell Death & Disease
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Migration of PAHs in the arable layer of flooded soil – model experiment

2014

Soils periodically, or permanently, waterlogged and soils exposed to flood waters are heavily imperilled to pollution of inorganic and organic compounds. They are primarily compounds that are brought with the inflowing (highly loaded) floodwater and indigenously produced within the soil profile by anaerobic metabolism of the organic matter. PAHs compounds are adsorbed by the soil from the floodwaters and move in the soil profile posing a threat to groundwater. In addition, when the flood recedes, these compounds may be taken up by the crops. In this study soil pollution with polycyclic aromatic hydrocarbons (PAHs) derived from the decomposition of organic matter and silt and their migration…

PAHsmigration of pollutantsfloodsoilEcological Chemistry and Engineering. A
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Early human peopling of Sicily: Evidence from the Mesolithic skeletal remains from Grotta d'Oriente

2010

The site of Grotta d'Oriente, Island of Favignana, Sicily has yielded the complete skeleton of an adult female (OB) dated to the Mesolithic age. The cranial morphometry of this individual can provide us with some useful information about the peopling of Sicily in the Early Holocene period.Morphological affinities of OB and other Sicilian Mesolithic specimens were assessed to verify hypotheses concerning the early peopling of Sicily.Craniofacial metric data were employed in a comparative analysis with European Upper Palaeolithic (UP), Mesolithic, Neolithic, and Copper/Bronze age samples, and contemporary Italians. Both a model-free and a model-bound approach were used not only to calculate c…

PALEOANTHROPOLOGY MORPHOMETRY SICILY MESOLITHIC SKELETON SICILIAN MESOLITHIC CRANIOFACIAL MORPHOMETRY MULTIVARIATE STATISTICSAdultGene FlowAgingCephalometryPhysiologyEpidemiologySettore BIO/08 - AntropologiaBone and BonesBronze AgeGeneticsHumansSicilyPhylogenyMesolithicHoloceneAdult femaleFossilsPublic Health Environmental and Occupational HealthEmigration and ImmigrationBiological EvolutionArchaeologylanguage.human_languageGeographylanguageFemaleSicilianAnnals of Human Biology
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Tazab, Haskoba, Fregata: emigracyjny biznes w Wielkiej Brytanii i wywiad PRL : lata 50. i 60. XX wieku

2014

During the first half of the 1960’s Polish immigrants in Great Britain owned approx. 3.5 thousand ventures. The immigration business structure was dominated by small companies, set on Polish customers, employing mainly Poles, the fastest developing branch were shipping companies. The direct contacts between the immigrants and the country contributed to creating Polish travel agencies. The PRL intelligence was trying to recruit the businessmen immigrants to become secret collaborators

PRL intelligenceFregataHaskobabusiness during immigrationTazabArchiwum Emigracji : studia, szkice, dokumenty
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Na celowniku tajnych służb PRL. Sprawa Aleksandra Demideckiego-Demidowicza

2014

Who was Aleksander Demidecki-Demidowicz. Without a doubt he was one of the most prominent politicians in exile in France. He was famous for his ability to win people over and to cooperate with people of different political views. His significance and role is best illustrated by the fact that in 1958 he was unanimously chosen as the leader of the Division of the National Council of Poland. It is no wonder that the intelligence services of the PRL government were interested in him. What were the consequences? Did Demidecki-Demidowicz really collaborate with the PRL authorities, or did he just play along in order to find out the plans of the communist secret service towards Polish emigrants? W…

PRLemigrationintelligenceThe National PartycommunismArchiwum Emigracji : studia, szkice, dokumenty
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Il Mediterraneo dell'architettura

2010

In the 1990s, the second and third series of the journal activated with this column the resumption in a structured way of the reasoning on the centrality of Sicily within the Mediterranean basin, to probe its historical multicultural vocation also in the architectural field. The investigation, which began in the didactic field with design courses by Culotta, Panzarella, Sarro, Giorgianni and with degree theses on the theme of the Western Mosque in Palermo and Mazara del Vallo, will continue later in a more extensive form with the design workshops on residences for immigrants in the historic center of Palermo, the results of which are documented in the text by Culotta and Sciascia, “L'archit…

Palermo Mediterraneo Culotta Panzarella migration SicilySettore ICAR/14 - Composizione Architettonica E Urbana
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Development of natural and synthetic compounds as kinase inhibitors targeting cancer cells and cancer stem cells

2023

Pancreatic ductal adenocarcinomaInhibition of migrationantibiotic resistanceImidazo[21-b][134]thiadiazole derivativeskinase inhibitorsanti-biofilm agentsAntiproliferative activityFAK inhibitionSettore CHIM/08 - Chimica Farmaceutica
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Les trajectoires scolaires des élèves issus de l'immigration selon le genre et l'origine : quelles évolutions ?

2016

En ligne sur http://www.cnesco.fr/wp-content/uploads/2016/09/brinbaum1.pdf; L'objectif de ce rapport est d'actualiser les connaissances sur la scolarité des élèves dits de la "seconde génération" -nés en France de parents immigrés - en prenant en compte la diversité des origines. Sont mobilisés quatre indicateurs : les notes en 6e et en 3e, la situation scolaire en 2012-2013 soit six ans après l'entrée en 6e (avec les filières suivies) et les aspirations des familles.

Panel 95[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationOrigine géographiqueTrajectoire scolaireÉvolutionImmigrationEnfant de migrantFranceGenrePanel 07
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D'une génération à l'autre, les aspirations éducatives des familles immigrées. Ambition et persévérance

2005

Panel 95[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationOrigine géographique[ SHS.EDU ] Humanities and Social Sciences/EducationImmigrationEnfant de migrant05031Origine socialeParcours scolaireFamilleAspiration scolaireRéussite scolaireProjet scolaire
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The Effects of Right-Wing Populist Communication on Emotions and Cognitions toward Immigrants

2018

The persuasiveness of right-wing populist communication has become a widely discussed topic; it is often assumed that such messages might foster anti-immigrant attitudes among citizens. The present study explores the effects of the different components of right-wing populist communication—anti-immigrant messages, populist content, and populist style—on attitudes toward immigrants. By combining a media content analysis ( N = 605 articles) with a panel survey ( N = 1,968) in metropolitan areas of four Western European countries (France, Germany, Switzerland, and the United Kingdom), this study analyzes how citizens’ attitudes toward immigrants are influenced by the right-wing populist commun…

Panel surveySociology and Political ScienceCommunicationmedia_common.quotation_subject05 social sciencesImmigration050801 communication & media studiesCognition0506 political sciencePopulism0508 media and communications10240 Department of Communication and Media Research3312 Sociology and Political ScienceRight wing050602 political science & public administrationPsychologySocial psychology070 News media journalism & publishing3315 Communicationmedia_commonThe International Journal of Press/Politics
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