Search results for "Moda"

showing 10 items of 1753 documents

Measuring Seasonality: Performance of Accommodation Establishments in Sicily through the analysis of Occupancy Rates

2011

Tourism, more than other fields, needs to be managed. As such, the provision of reliable information and adequate tools is one of the major challenges to monitor and to manage tourism destinations. Sicily (Italy) seems to have a great potential coming from its tourism resources, and most of the recent development programs have been focused on tourism. In line with the world’s trend, tourism in Sicily faced a growth in terms of overnight stays, from about 9 millions in 1994, to more than 14 millions in 2007. The regional expenditure in tourism from 1996 to 2006 was of euro 785 millions (Federalberghi, 2007), which ranks Sicily as the second region in Italy for tourism expenditure, in the yea…

Public economicsOccupancybusiness.industrySeasonalitySupply sideSeasonalitymedicine.diseaseGeographyEconomyPolicy decisionSeasonality measures occupancy rate Sicily ItalymedicineSettore SECS-S/05 - Statistica SocialeOccupancy rateFixed costbusinesstourism demandAccommodationSicilyTourism
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Economic evaluation of sublingual immunotherapy vs. symptomatic treatment in allergic asthma.

2009

Background The worldwide increased prevalence of allergic diseases, and especially of respiratory allergy, is paralleled by increased health costs. This requires consideration of the cost to efficacy ratio of the available treatment to identify the optimal choice. Objective To compare the different economic relevance, over a long evaluation time, of symptomatic pharmacologic therapy and sublingual immunotherapy (SLIT) in patients with allergic asthma. Methods Seventy patients with perennial allergic asthma, sensitized to dust mites, were enrolled; 50 of these patients were treated with SLIT against house dust mites and 20 were treated with symptomatic drugs. The patients were evaluated for …

Pulmonary and Respiratory MedicineAdultMalemedicine.medical_specialtyAllergyAdolescentCost-Benefit AnalysisImmunologyPopulationAdministration SublingualFollow-Up StudieSublingual administrationDrug TherapyImmunopathologyInternal medicinemedicineImmunology and AllergyHumansCost-Benefit AnalysieducationChildAsthmaeducation.field_of_studyDrug Therapy; Combined Modality Therapy; Immunotherapy; Humans; Asthma; Child; Health Care Costs; Cost-Benefit Analysis; Adult; Middle Aged; Follow-Up Studies; Adolescent; Administration Sublingual; Male; Femalebusiness.industryRespiratory diseaseHealth Care CostsMiddle Agedmedicine.diseaseSlitCombined Modality TherapyAsthmaSurgeryHealth Care CostObservational studyFemaleImmunotherapybusinessHumanFollow-Up StudiesAnnals of allergy, asthmaimmunology : official publication of the American College of Allergy, Asthma,Immunology
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Asthma management in a specialist setting: Results of an Italian Respiratory Society survey.

2017

Abstract Background Asthma considerably impairs patients' quality of life and increases healthcare costs. Severity, morbidity, and degree of disease control are the major drivers of its clinical and economic impact. National scientific societies are required to monitor the application of international guidelines and to adopt strategies to improve disease control and better allocate resources. Aim to provide a detailed picture of the characteristics of asthma patients and modalities of asthma management by specialists in Italy and to develop recommendations for the daily management of asthma in a specialist setting. Method: A quantitative research program was implemented. Data were collected…

Pulmonary and Respiratory MedicineAdultMalemedicine.medical_specialtyConcordanceSocio-culturalePractice PatternsSettore MED/10 - Malattie Dell'Apparato RespiratorioSeverity of Illness Index03 medical and health sciences0302 clinical medicineQuality of life (healthcare)Retrospective StudieSurveys and QuestionnairesSeverity of illnessHealth caremedicineSurveys and QuestionnaireHumansPharmacology (medical)030212 general & internal medicinePractice Patterns Physicians'Adult; Aged; Asthma; Female; Humans; Italy; Male; Middle Aged; Practice Patterns Physicians'; Retrospective Studies; Severity of Illness Index; Surveys and Questionnaires; Quality of Life; SpecializationAsthmaAgedRetrospective StudiesModalitiesPhysicians'business.industryBiochemistry (medical)Retrospective cohort studyMiddle Agedmedicine.diseaseAsthmaPulmonary and Respiratory Medicine; Biochemistry (medical); Pharmacology (medical)030228 respiratory systemItalyTest scoreFamily medicinePhysical therapyQuality of LifeFemalebusinessHumanSpecializationPulmonary pharmacologytherapeutics
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Implantation of Gore-Tex chordae on aortic valve leaflet to treat prolapse using "the chordae technique": surgical aspects and clinical results.

2008

Background Repair of prolapsed aortic valve leaflets has been considered a challenging technique for cardiac surgeons. In this paper we describe our surgical approach, "the chordae technique." It consists of the correction of aortic cusp prolapse by shortening the free margin length and of an adjustment of the leaflets coaptation height by anchoring the prolapsing cusp to the aortic wall at the sinotubular junction level. Methods Between February 2003 and December 2006, 26 patients with one or more prolapsed aortic leaflets underwent surgical repair using the new approach. The mean age of patients was 55 ± 10 years. There were 10 (38.5%) patients with grade II aortic valve regurgitation, 4 …

Pulmonary and Respiratory MedicineAortic valveMalemedicine.medical_specialtyAortic Valve InsufficiencyComorbidityAortic aneurysmPostoperative ComplicationsInternal medicinemedicineHumanscardiovascular diseasesCardiac skeletonPolytetrafluoroethyleneAortic valve regurgitationAgedSurgical repairAortic Valve ProlapseHeart Valve Prosthesis ImplantationAortic Aneurysm Thoracicbusiness.industrySinotubular JunctionSuture TechniquesMiddle Agedmedicine.diseaseCombined Modality TherapySurgerymedicine.anatomical_structureCardiothoracic surgeryAortic ValveHeart Valve ProsthesisCirculatory systemcardiovascular systemCardiologyChordae TendineaeSurgeryFemaleCardiology and Cardiovascular MedicinebusinessEchocardiography TransesophagealFollow-Up StudiesThe Annals of thoracic surgery
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Chirurgie des métastases pulmonaires des cancers colorectaux : facteurs prédictifs de survie

2016

Resume Introduction Le cancer colorectal represente la 3e cause de mortalite par cancer : 5 % des patients vont developper des metastases pulmonaires. Le concept de chirurgie des cancers oligometastatiques est base sur l’objectif d’un controle local optimal de la maladie. Etat des connaissances A ce jour, aucun essai controle randomise ne valide la chirurgie de resection des metastases pulmonaires des patients oligometastatiques porteurs d’un cancer colorectal controle localement. Cependant, de nombreuses series, le plus souvent retrospectives, rapportent des survies prolongees chez des patients tres selectionnes, allant de 45 a 65 % a 5 ans dans les series les plus recentes. Les facteurs c…

Pulmonary and Respiratory MedicineGynecology03 medical and health sciencesmedicine.medical_specialty0302 clinical medicinebusiness.industry030220 oncology & carcinogenesisMultimodality Treatmentmedicine030204 cardiovascular system & hematologybusinessRevue des Maladies Respiratoires
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Cardioprotective effects of the serine protease inhibitor aprotinin after regional ischemia and reperfusion on the beating heart.

2002

AbstractObjective: Early coronary reperfusion of the ischemic myocardium is a desired therapeutic goal to preserve myocardium. However, reperfusion itself contributes to an additional myocardial injury (ie, reperfusion injury), which has been attributed to neutrophil infiltration with subsequent release of proteases and oxygen-derived radicals. We studied the effects of the serine protease inhibitor aprotinin (Trasylol) on myocardial ischemia and reperfusion in a rat model. Methods: The effects of aprotinin (5000 and 20,000 U/kg) were examined in vivo in a rat model of regional myocardial ischemia (20 minutes) and long-term reperfusion (24 hours). Cardioprotecive effects were determined by …

Pulmonary and Respiratory MedicineMaleProteasesCardiotonic AgentsSerine Proteinase InhibitorsNeutrophilsHeart VentriclesIschemiaMyocardial IschemiaApoptosisMyocardial ReperfusionMyocardial Reperfusion InjuryPharmacologyRats Sprague-DawleyLeukocyte CountAprotininIn vivoMedicineAnimalsAprotininCreatine KinasePeroxidaseCardioprotectionbiologyDose-Response Relationship Drugbusiness.industryMyocardiumModels Cardiovascularmedicine.diseaseCombined Modality TherapyRatsDisease Models AnimalTreatment OutcomeEnzyme inhibitorAnesthesiabiology.proteinSurgeryCreatine kinaseCardiology and Cardiovascular MedicinebusinessReperfusion injuryBiomarkersmedicine.drugThe Journal of thoracic and cardiovascular surgery
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External reinforcement of varicose veins with PTFE prosthesis in infrainguinal bypass surgery -- clinical results.

2003

OBJECTIVE Segmental varicose degeneration of the autogenous greater saphenous vein may limit its use in infrainguinal bypass surgery. Wrapping a PTFE prosthesis around dilated veins has emerged as an option to create externally reinforced vein bypasses. Results regarding graft patency and limb salvage were analyzed. METHODS Between September 1995 and January 2001, 35 infrainguinal bypass operations in 33 patients were performed with greater saphenous veins exhibiting segmental varicose dilatation. Grafts were followed by duplex scan and retrospective analysis of graft patency and limb salvage was performed. RESULTS One bypass prompted successful revision for early occlusion. Four bypasses r…

Pulmonary and Respiratory MedicineMaleReoperationmedicine.medical_specialtyTime FactorsPopliteal VeinLimb salvagemedicine.medical_treatmentInfrainguinal bypassGreater saphenous veinInguinal CanalProsthesisSeverity of Illness IndexTimeVaricose VeinsBlood Vessel Prosthesis ImplantationCoated Materials BiocompatibleOcclusionVaricose veinsMedicineHumansSaphenous VeinVeinPolytetrafluoroethyleneVascular PatencyAgedRetrospective StudiesAged 80 and overbusiness.industryGraft Occlusion VascularMiddle Agedmedicine.diseaseCombined Modality TherapySurvival AnalysisSurgeryRadiographyStenosismedicine.anatomical_structureTreatment OutcomeSurgeryFemalemedicine.symptomCardiology and Cardiovascular MedicinebusinessFollow-Up StudiesThe Thoracic and cardiovascular surgeon
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Effects Of Whole Body Vibration In Patients With Chronic Obstructive Pulmonary Disease - A Randomized Controlled Trial

2012

Summary Introduction To date endurance and strength training are established and evidence-based exercise methods in patients with chronic obstructive pulmonary disease (COPD). There is an unmet need for further research in new and complementary exercise modalities. Additional whole body vibration training during pulmonary rehabilitation may be such a new approach that has not yet been investigated in patients with COPD. Methods Eighty-two patients (65 ± 9 yrs, FEV 1 pred. 38 ± 11%, female 51%) with COPD in GOLD stage III to IV assessed for a 3-week inpatient multidisciplinary rehabilitation program were on top randomly assigned to one of two intervention groups: (1) 3 × 3 min of bilateral d…

Pulmonary and Respiratory MedicineMalemedicine.medical_specialtyTime FactorsStrength trainingmedicine.medical_treatmentSquatWalkingVibrationlaw.inventionPulmonary Disease Chronic ObstructiveRandomized controlled trialQuality of lifelawTrainingHumansMedicineWhole body vibrationIn patientPulmonary rehabilitationProspective StudiesProspective cohort studyExercisePhysical Therapy ModalitiesAgedCOPDExercise Tolerancebusiness.industryChronic obstructive pulmonary diseaseMinimal clinically important differencemedicine.diseaseRespiratory MusclesExercise TherapyRespiratory Function TestsPulmonary rehabilitationTreatment OutcomePhysical therapyFemalebusinessWhole body vibrationA107. ASSESSMENT, EXERCISE TRAINING AND OUTCOMES
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An open-label, prospective phase I/II study evaluating the immunogenicity and safety of a ras peptide vaccine plus GM-CSF in patients with non-small …

2007

Mutations of the ras gene have been reported in 20-40% of NSCLC patients. If present, they are critical for the malignant phenotype of these tumors. Therefore, targeting them by specific vaccination is a promising therapeutic approach. In a clinical trial we screened for ras mutations in patients with NSCLC. Patients with ras-positive tumors were immunized six times intradermally with a mixture of seven peptides representing the most common ras mutations. Objectives of the study were the feasibility, efficacy and safety of the vaccination. In addition, the induction of a specific immune reaction was investigated by DTH tests, and the induction of peptide-specific T cells was tested in ex vi…

Pulmonary and Respiratory MedicineOncologyMaleCancer Researchmedicine.medical_specialtyLung Neoplasmsmedicine.medical_treatmentT-LymphocytesCancer VaccinesImmune systemInternal medicineCarcinoma Non-Small-Cell LungCarcinomaMedicineHumansLung cancerCodonAgedNeoplasm StagingImmunity Cellularbusiness.industryImmunogenicityRas PeptideVaccinationGranulocyte-Macrophage Colony-Stimulating FactorImmunotherapyMiddle Agedmedicine.diseaseCombined Modality TherapyPeptide FragmentsRecombinant ProteinsVaccinationOncologyImmunologyMutationras ProteinsFemaleImmunotherapybusinessEx vivoLung cancer (Amsterdam, Netherlands)
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A Tomographical Characterization of L-convex Polyominoes

2005

Our main purpose is to characterize the class of L-convex polyominoes introduced in [3] by means of their horizontal and vertical projections. The achieved results allow an answer to one of the most relevant questions in tomography i.e. the uniqueness of discrete sets, with respect to their horizontal and vertical projections. In this paper, by giving a characterization of L-convex polyominoes, we investigate the connection between uniqueness property and unimodality of vectors of horizontal and vertical projections. In the last section we consider the continuum environment; we extend the definition of L-convex set, and we obtain some results analogous to those for the discrete case.

Pure mathematicsInteger VectorHorizontal and verticalPolyominoDiscrete TomographyConvex setDiscrete geometryUnimodalityConnection (mathematics)Vertical ProjectionContinuum CounterpartMonotone PathUniquenessDiscrete tomographyMathematics
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