Search results for "Mono"
showing 10 items of 6843 documents
Intramolecular Hydrogen Bond, Hirshfeld Analysis, AIM; DFT Studies of Pyran-2,4-dione Derivatives
2021
Intra and intermolecular interactions found in the developed crystals of the synthesized py-ron-2,4-dione derivatives play crucial rules in the molecular conformations and crystal stabili-ties, respectively. In this regard, Hirshfeld calculations were used to quantitatively analyze the different intermolecular interactions in the crystal structures of some functionalized py-ran-2,4-dione derivatives. The X-ray structure of pyran-2,4-dione derivative namely (3E,3′E)-3,3′-((ethane-1,2-diylbis(azanediyl))bis(phenylmethanylylidene))bis(6-phenyl-2H-pyran-2,4(3H)-dione) was determined. It crystallized in the monoclinic crystal system and C2/c space group with unit cell parameters: a = 14.0869(4) …
Desarrollo y evaluación de materiales porosos en técnicas analíticas de extracción y separación miniaturizadas
2021
La presente Tesis Doctoral contempla dos grandes líneas de actuación. La primera de ellas consiste en la síntesis, caracterización y modificación de materiales porosos para su uso como sorbentes en técnicas miniaturizadas de extracción en fase sólida (Solid-Phase Extraction, SPE) de analitos de interés biológico y medioambiental (fármacos, péptidos, proteínas, y contaminantes) utilizándose para ello diferentes formatos o soportes de extracción de uso común en el laboratorio químico tales como jeringas, columnas de centrífuga, etc. con diversos materiales híbridos desarrollados a este respecto (Objetivo i). La segunda línea de actuación consiste en la puesta a punto de metodologías sencillas…
Strongly Coupled Coherent Phonons in Single-Layer MoS 2
2019
We present a transient absorption setup combining broadband detection over the visible-UV range with high temporal resolution ($\sim$20fs) which is ideally suited to trigger and detect vibrational coherences in different classes of materials. We generate and detect coherent phonons (CPs) in single layer (1L) MoS$_2$, as a representative semiconducting 1L-transition metal dichalcogenide (TMD), where the confined dynamical interaction between excitons and phonons is unexplored. The coherent oscillatory motion of the out-of-plane $A'_{1}$ phonons, triggered by the ultrashort laser pulses, dynamically modulates the excitonic resonances on a timescale of few tens fs. We observe an enhancement by…
Enterobacter cloacae administration induces hepatic damage and subcutaneous fat accumulation in high-fat diet fed mice.
2018
Accumulating evidence indicates that gut microbiota plays a significant role in obesity, insulin resistance and associated liver disorders. Family Enterobacteriaceae and especially Enterobacter cloacae strain B29 have been previously linked to obesity and hepatic damage. The underlying mechanisms, however, remain unclear. Therefore, we comprehensively examined the effects of E. cloacae subsp. cloacae (ATCC® 13047™) administration on host metabolism of mice fed with high-fat diet (HFD). C57BL/6N mice were randomly divided into HFD control, chow control, and E. cloacae treatment groups. The E. cloacae treatment group received live bacterial cells in PBS intragastrically twice a week, every ot…
Lack of reactivation of tuberculosis in patients with psoriasis treated with secukinumab in a real-world setting of latent tuberculosis infection
2022
Background Some biologics for psoriasis, especially anti-tumor necrosis factor (TNF)-alpha therapies, may re-activate latent tuberculosis (TBC) infection with consequent morbidity and mortality. However, there is a low reported incidence of conversion to positive TBC status among patients with psoriasis treated with second-generation biologic therapies, particularly anti-interleukin (IL)-17 therapies such as secukinumab. Objectives To evaluate the safety profile of secukinumab in psoriasis patients with latent TBC infection. Methods Real-life data were collected by retrospective chart review on patients with moderate-to-severe psoriasis who showed positivity for TBC screening at baseline an…
Análisis y Evaluación del tratamiento de la isquemia crítica de miembros inferiores no revascularizable mediante trasplante autólogo de progenitores …
2015
La enfermedad arterial periférica constituye una de las enfermedades con mayor impacto en la calidad de vida de los pacientes. La isquemia crítica de miembros inferiores es el estadio terminal de la enfermedad arterial periférica y presenta elevadas tasas de amputación de la extremidad a pesar del correcto tratamiento. En los últimos años, diversas publicaciones han mostrado efectos terapéuticos con el uso de células pluripotenciales obtenidas desde médula ósea en el tratamiento de la isquemia crítica sin opciones de revascularización, en lo que se ha llamado Angiogénesis Terapéutica. El objetivo de este estudio fue demostrar que, mediante el trasplante autólogo de progenitores hematopoyéti…
Potential-assisted deposition of mixed alkanethiol self-assembled monolayers
2010
Abstract Preparation of self-assembled monolayers (SAMs) usually involves passive incubation. The recently developed potential-assisted deposition is indeed more selective as well as 100-fold faster than passive adsorption, thereby enhancing the reproducibility of the monolayer deposition. This article aims to identify the electrodeposition conditions necessary to prepare mixed alkanethiol SAMs on gold surface. Parameters such as concentrations in solution, electrode polarization and deposition time were examined for two chain lengths, C 3 (mercaptopropionic acid, MPA) and C 18 (octadecanethiol, ODT). The kinetics and composition of the SAMs were systematically characterized by reductive st…
Tytuły we frazeograficznej perspektywie opisu
2016
Tytuły utworów literackich, muzycznych, malarskich czy filmowych należą do zbioru nazw własnych, których główną funkcją jest identyfikowanie poszczególnych obiektów (dzieł sztuki). Tym samym tytuły należą do klasy reproduktów, gdyż w tekstach muszą być reprodukowane w ustalonej dla danego języka formie. Tworzy to istotny problem dla tłumaczy, zwłaszcza w przekładzie tekstów, które zawierają w sobie tytuły. W artykule stawiana jest teza, że wprowadzanie tytułów do słowników ogólnych i/lub tworzenie specjalnych słowników przekładowych mogłoby rozwiązać ten problem translatorski. Jednak tytuły należą do „nieprototypowych obiektów frazeografii” i dlatego reguły rządzące ich kodyfikacją słowniko…
RSV disease in infants and young children: Can we see a brighter future?
2022
Respiratory syncytial virus (RSV) is a highly contagious seasonal virus and the leading cause of Lower Respiratory Tract Infections (LRTI), including pneumonia and bronchiolitis in children. RSV-related LRTI cause approximately 3 million hospitalizations and 120,000 deaths annually among children <5 years of age. The majority of the burden of RSV occurs in previously healthy infants. Only a monoclonal antibody (mAb) has been approved against RSV infections in a restricted group, leaving an urgent unmet need for a large number of children potentially benefiting from preventive measures. Approaches under development include maternal vaccines to protect newborns, extended half-life monoclon…
Tree species influences diversity of ground-dwelling insects in afforested fields
2015
Abstract Impaired natural ecosystems, such as agricultural lands, are restored toward original or other target stage. Because the long agricultural history has changed the physical, chemical and biological features of the soil, afforested fields can harbor novel species assemblages and interactions. Our overall aim was to quantify the diversity of ground beetles and ants in early successional afforested fields. In a large scale field experiment, we compared plots that had been afforested 25 years ago by planting monocultures of birch, pine or spruce trees. A total of 4080 carabid individuals representing 41 species, and 131,933 ant individuals representing 15 species were recorded. Both the…