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MycoKey Round Table Discussions of Future Directions in Research on Chemical Detection Methods, Genetics and Biodiversity of Mycotoxins

2018

MycoKey, an EU-funded Horizon 2020 project, includes a series of “Roundtable Discussions” to gather information on trending research areas in the field of mycotoxicology. This paper includes summaries of the Roundtable Discussions on Chemical Detection and Monitoring of mycotoxins and on the role of genetics and biodiversity in mycotoxin production. Discussions were managed by using the nominal group discussion technique, which generates numerous ideas and provides a ranking for those identified as the most important. Four questions were posed for each research area, as well as two questions that were common to both discussions. Test kits, usually antibody based, were one major focus of the…

0301 basic medicineProteomicsSettore CHIM/01 - CHIMICA ANALITICAComputer scienceHealth Toxicology and MutagenesisBiodiversitylcsh:Medicinebiological controlmicrobiomeToxicology//purl.org/becyt/ford/1 [https]transcriptomicscommunication with non-scientistsA better understanding of metabolomics from the cellular to the ecosystem level is needed to inform and control mycotoxin production control and remediation. Antibody-based diagnostics have become an acceptable standard in many practical applications but sophisticated multi-mycotoxin detection protocols are the future for many official regulatory controls especially as the number of toxins that are regulated increases and need more standardization and cross-laboratory validation.antibodies2. Zero hungerGeneticsbiologyNominal groupBiodiversitymetabolomicsGeneral partnershipBiological controlAntibodiesBiological controlCommunication with non-scientists Metabolomics Microbiome Multi-mycotoxin detection protocols Nominal group discussion technique ProteomicsTranscriptomicsmulti-mycotoxin detection protocolsSettore AGR/12 - PATOLOGIA VEGETALECommunication with non-scientistsEnvironmental MonitoringNominal group discussion techniqueOpinionAntibodies03 medical and health sciencesMycotoxicologyBiointeractions and Plant HealthproteomicsFood supplyAnimalsHumansMetabolomicsnominal group discussion technique//purl.org/becyt/ford/1.6 [https]Transcriptomicsbusiness.industryResearchlcsh:RUsabilityMycotoxinsbiology.organism_classification030104 developmental biologyMulti-mycotoxin detection protocolsRound tableRankingMicrobiomeEPSbusinesscommunication with non-scientistToxins
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Brain Control of Plasma Cholesterol Involves Polysialic Acid Molecules in the Hypothalamus

2017

IF 3.566; International audience; The polysialic acid (PSA) is a large glycan that is added to cell-surface proteins during their post-translational maturation. In the brain, PSA modulates distances between cells and controls the plasticity of the nervous system. In the hypothalamus, PSA is involved in many aspects of energy balance including food intake, osmoregulation, circadian rhythm, and sleep. In this work, we investigated the role of hypothalamic PSA in the regulation of plasma cholesterol levels and distribution. We report that HFD consumption in mice rapidly increased plasma cholesterol, including VLDL, LDL, and HDL-cholesterol. Although plasma VLDL-cholesterol was normalized withi…

0301 basic medicineVery low-density lipoprotein[SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiologyurologic and male genital diseaseschemistry.chemical_compound0302 clinical medicinemaladie cardiovasculairehypothalamusOriginal Research[SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism2. Zero hungerGeneral Neurosciencecholestérol[ SDV.MHEP.EM ] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism[SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolismHypothalamus[ SDV.NEU.NB ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/NeurobiologyAlimentation et NutritionOsmoregulationcerveaulipids (amino acids peptides and proteins)medicine.medical_specialtypolysialic acidHDLBiologylcsh:RC321-571LDL03 medical and health sciencespolysialic acid;hypothalamus;atherosclerosis;HDL;LDL;synaptic plasticityInternal medicinemedicineFood and NutritionCircadian rhythmlcsh:Neurosciences. Biological psychiatry. Neuropsychiatrysynaptic plasticityCholesterolPolysialic acidNeurosciencesathérosclérose[SDV.NEU.NB] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiologynutritional and metabolic diseasesmedicine.disease030104 developmental biologyEndocrinologychemistryNeurons and Cognitionatherosclerosis030217 neurology & neurosurgeryDyslipidemiaHomeostasisNeuroscienceFrontiers in Neuroscience
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Molecular Insights Into Therapeutic Potential of Autophagy Modulation by Natural Products for Cancer Stem Cells

2020

Autophagy, a cellular self-digestion process that is activated in response to stress, has a functional role in tumor formation and progression. Cancer stem cells (CSCs) accounting for a minor proportion of total cancer cells-have distinct self-renewal and differentiation abilities and promote metastasis. Researchers have shown that a numeral number of natural products using traditional experimental methods have been revealed to target CSCs. However, the specific role of autophagy with respect to CSCs and tumorigenesis using natural products are still unknown. Currently, CSCs are considered to be one of the causative reasons underlying the failure of anticancer treatment as a result of tumor…

0301 basic medicineautophagycancer stem cellnatural productsReviewCell fate determinationBiologymedicine.disease_causeMetastasisCell and Developmental Biologystemness03 medical and health sciences0302 clinical medicineCancer stem cellmedicinelcsh:QH301-705.5Transcription factorAutophagychemoresistanceCancerCell Biologymedicine.diseaseTumor formation030104 developmental biologylcsh:Biology (General)030220 oncology & carcinogenesisCancer researchCarcinogenesisDevelopmental BiologyFrontiers in Cell and Developmental Biology
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Functional Gustatory Role of Chemoreceptors in Drosophila Wings

2016

Summary: Neuroanatomical evidence argues for the presence of taste sensilla in Drosophila wings; however, the taste physiology of insect wings remains hypothetical, and a comprehensive link to mechanical functions, such as flight, wing flapping, and grooming, is lacking. Our data show that the sensilla of the Drosophila anterior wing margin respond to both sweet and bitter molecules through an increase in cytosolic Ca2+ levels. Conversely, genetically modified flies presenting a wing-specific reduction in chemosensory cells show severe defects in both wing taste signaling and the exploratory guidance associated with chemodetection. In Drosophila, the chemodetection machinery includes mechan…

0301 basic medicinemelanogasterTasteChemoreceptor[ SDV.BA.ZI ] Life Sciences [q-bio]/Animal biology/Invertebrate ZoologyneuronsInsectmale courtship behavior[SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC]Animals Genetically Modified0302 clinical medicineCytosolConditioning PsychologicalDrosophila ProteinsWings AnimalSensillalcsh:QH301-705.5media_commonAnimal biologybiologyBehavior AnimalAnatomytransductionbitterChemoreceptor CellsDrosophila melanogasterTasteAlimentation et Nutritioncandidate taste receptors;male courtship behavior;apis-mellifera;insect flight;gene;trasnsduction;melanogaster;odorant;neurons;bitterinsect flightanimal structuresmedia_common.quotation_subjectCarbohydratesTime-Lapse ImagingGeneral Biochemistry Genetics and Molecular BiologyFluorescence03 medical and health sciencesBiologie animalecandidate taste receptorsAnimalsFood and Nutrition[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyCalcium SignalingRNA Messengerapis-melliferageneDrosophilaodorantWingfungiNeurosciencesWater[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biology[SDV.BDD.MOR]Life Sciences [q-bio]/Development Biology/Morphogenesisbiology.organism_classification[SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology[SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal genetics030104 developmental biologylcsh:Biology (General)FoodNeurons and CognitionCalciumNeuroscience030217 neurology & neurosurgery
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Guía para la incorporación de la perspectiva de género en la docencia en Sociología, Economía y Ciencias Políticas

2019

Sociology has constructed a male worldview that entails a biased interpretation of social reality. For its part, the traditional economy has made invisible the dependence of the commercial sphere of the domestic sphere. And in the field of political science, we also find many gender biases in basic concepts such as justice, equality or citizenship. This article, based on the work done by the authors in the Guia per a una docència universitària amb perspectiva de gènere de Sociologia, Economia i Ciència Política, offers some proposals, teaching resources and consultation tools to introduce the gender perspective in teaching, knowledge transfer and research in these disciplines.

1137-7038 8537 Arxius de sociologia 525290 2019 40 7038142 Guía para la incorporación de la perspectiva de género en la docencia en Sociologíaoffers some proposalsEconomia i Ciència PolíticaEconomía y Ciencias Políticas Ortiz MoneraAnna Sociology has constructed a male worldview that entails a biased interpretation of social reality. For its part:SOCIOLOGÍA [UNESCO]Rosaguías docentesGender perspectiveknowledge transfer and research in these disciplines. perspectiva de géneroequality or citizenship. This articlesesgo androcéntricobased on the work done by the authors in the Guia per a una docència universitària amb perspectiva de gènere de Sociologiawe also find many gender biases in basic concepts such as justiceUNESCO::SOCIOLOGÍAandrocentric biasthe traditional economy has made invisible the dependence of the commercial sphere of the domestic sphere. And in the field of political scienceteaching resources and consultation tools to introduce the gender perspective in teachingMorero Beltránteaching guides 71 76
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Thermomineral waters of Greece: geochemical characterization

2020

75 °C). In terms of pH most results vary from 5.5 to 823 °C) ii) warm (23 40 °C) iii) thermal (40 75 °C) and iv) hyperthermal (&gtfew springs show either very low pH (&lt10) proposing serpentinization processes. Regarding TDS concentrations collected waters can be subdivided into low salinity (up to 1.5 g/L) brackish (up to 20 g/L) and saline (up to 43 g/L). The medium high salinities can be justified by mixing with sea water and/or strong waterrock interaction processes. Isotope composition of O and H ranges from 12.7 to +2.7 ‰ SMOW and from 91 to +12 ‰ SMOW respectively and is generally comprised between the Global Meteoric Water Line and the East Mediterranean Meteoric Water Line. Only few water samples show a positive shift for δ18O possibly related to high temperature waterrock interaction processes. Carbon dioxide (18 997000 μmol/mol) or N2 (1100 989000 μmol/mol) or CH4 (&ltMany geothermal areas of Greece are located in regions affected by Miocene or Quaternary volcanism and in continental basins characterised by elevated heat flow. Moreover the majority of them is found along the coast as well as in islands of the Aegean Sea and thus thermal water is often brackish to saline due to marine intrusion into costal aquifer. In the present study almost 300 thermal and cold mineral water samples were collected along the Hellenic territory with their physicochemical parameters (temperature pH electrical conductivity and Eh) and the amount of bicarbonates (titration with 0.1N HCl) being determined in situ. Additionally gases found either in free or dissolved phase were sampled. Both water and gas samples were analysed at the INGVPa laboratories for major ions (Ion Chromatography) silica (Inductively Coupled Plasma Optical Emission Spectrometry) chemical composition of free and dissolved gases (Gas Chromatography) water isotopes (O and H) and carbon and helium isotopes of free and dissolved gases (Mass Spectrometry). The temperature of the investigated waters ranges from 6.5 to 98°C pH from 1.96 to 11.98 whilst Total Dissolved Solids (TDS) from 0.06 to 43 g/L. Based on the temperature parameter waters can be divided into four groups: i) cold (&lt0.5 913000 μmol/mol) are the prevailing gas species found in the studied sites. The δ13CCO2 values ranged from 20.1 to +8.5 ‰ whilst the isotope ratio of He from 0.21 to 6.71 R/RA.4) suggesting interaction with H2Srich gases or very high pH values (&gtSettore GEO/08 - Geochimica E Vulcanologia
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La reproducción asistida y la filiación. Especial referencia al caso de las parejas de mujeres homosexuales

2018

This paper analyses, in general, the evolution that has had the art. 7.3 LTRHA since its introduction by the Act 3/2007, 15 march. In that way, it shows which has been the legislator´s solution about the use of assisted reproduction tecniques by homosexual women couples. Likewise, it studies which resolutions on the matter have been more relevant in the last years. All this, to set out the legislator´s failure and the need to reformulate the filiation regime in face of the challenge that assisted reproduction implies.

:CIENCIAS JURÍDICAS [UNESCO]2386-4567 22661 Actualidad jurídica iberoamericana 502169 2018 9 6653332 La reproducción asistida y la filiación. Especial referencia al caso de las parejas de mujeres homosexuales Muñoz Rodrigoinseminación artificialdetermination of filiationimpugnación de la filiaciónGonzalo This paper analysesthe evolution that has had the art. 7.3 LTRHA since its introduction by the Act 3/2007assisted reproductionartificial inseminationclaim of filiationto set out the legislator´s failure and the need to reformulate the filiation regime in face of the challenge that assisted reproduction implies. Filiacióndeterminación de la filiaciónparejas homosexuales.Filiationreproducción asistidaUNESCO::CIENCIAS JURÍDICAS15 march. In that wayin generalit studies which resolutions on the matter have been more relevant in the last years. All thishomosexual couples. 376 401reclamación de la filiaciónobjection of filiationit shows which has been the legislator´s solution about the use of assisted reproduction tecniques by homosexual women couples. Likewise
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Derecho y conciencia en Antígona: Una respuesta atemporal a los conflictos de familia

2018

El presente artículo aborda la importancia de la familia en Antígona, de Sófocles. Ante el Decreto de Creonte, por el que se prohibía, bajo pena de muerte, enterrar y llorar a Polinices, su hermana ?Antígona ? no duda en afirmar que por encima de las leyes del Estado está la ley de los dioses y la ley que dicta su conciencia, la que le exige anteponer los lazos familiares al orden público. Un acto de desobediencia civil que le conducirá a muerte.

:CIENCIAS JURÍDICAS [UNESCO]bajo pena de muertela que le exige anteponer los lazos familiares al orden público. Un acto de desobediencia civil que le conducirá a muerte. FamiliaPositive Lawliteratureliteraturaley positivacivil disobedience. 224 251por el que se prohibíaNatural Law2386-4567 22661 Actualidad jurídica iberoamericana 502169 2018 9 6653326 Derecho y conciencia en Antígona: Una respuesta atemporal a los conflictos de familia AdamsObarrio MorenoJuan Alfredo El presente artículo aborda la importancia de la familia en Antígonaenterrar y llorar a PolinicesUNESCO::CIENCIAS JURÍDICASUna respuesta atemporal a los conflictos de familia Adams [2386-4567 22661 Actualidad jurídica iberoamericana 502169 2018 9 6653326 Derecho y conciencia en Antígona]de Sófocles. Ante el Decreto de Creonteley naturalsu hermana ?Antígona ? no duda en afirmar que por encima de las leyes del Estado está la ley de los dioses y la ley que dicta su concienciaFamilydesobediencia civilSandra
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El TEDH y la Contaminación Acústica: Comentario a la STEDH sobre el caso cCuenca Zarzoso C. España

2018

El presente texto analiza el último caso originario de España sobre contaminación acústica y su afección al derecho a la protección de la privacidad reconocido en el artículo 8 CEDH. Se lleva a cabo de manera conjunta con el caso Moreno Gómez, habida cuenta de sus similitudes.

:CIENCIAS JURÍDICAS [UNESCO]contaminación acústicahabida cuenta de sus similitudes. Derecho a la privacidadRight to privacyUNESCO::CIENCIAS JURÍDICASnoise pollutionJorge Antonio El presente texto analiza el último caso originario de España sobre contaminación acústica y su afección al derecho a la protección de la privacidad reconocido en el artículo 8 CEDH. Se lleva a cabo de manera conjunta con el caso Moreno Gómezderecho a un medio ambiente sano.Comentario a la STEDH sobre el caso cCuenca Zarzoso C. España Climent Gallart [2386-4567 22661 Actualidad jurídica iberoamericana 502169 2018 9 6653339 El TEDH y la Contaminación Acústica]right to a healthy environment. 526 5352386-4567 22661 Actualidad jurídica iberoamericana 502169 2018 9 6653339 El TEDH y la Contaminación Acústica: Comentario a la STEDH sobre el caso cCuenca Zarzoso C. España Climent Gallart
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Determinación de la edad de un extranjero indocumentado : A propósito de la sentencia de la audiencia provincial de barcelona, de 24 de enero de 2020

2021

In recent years, immigration of minors has increased, which means that administrations establish a differentiated treatment for this sector of immigration due to the fact that they are minors; There are many aspects to take into account in these cases, including verifying the minority age, a fact that is more complicated when it comes to adolescents. This is what is analyzed by the Judgment of the Provincial Court of Barcelona, of January 24, 2020, which confirms the Resolution of the General Directorate of Attention to Children and Adolescents, which agreed to the closure of the homelessness file and the admission of the plaintiff in a Protection Center until the verification of their pers…

:CIENCIAS JURÍDICAS [UNESCO]de 24 de enero de 2020 Ortega Giménezwhich confirms the Resolution of the General Directorate of Attention to Children and AdolescentsLerdys Saray In recent yearsimmigration of minors has increasedminorityimmigration. 550 575There are many aspects to take into account in these casesincluding verifying the minority ageAlfonsowhich agreed to the closure of the homelessness file and the admission of the plaintiff in a Protection Center until the verification of their personal circumstancesmayoría de edadminoría de edadof January 242020since it did not provide any type of documentation. Menor extranjero no acompañadoinmigraciónHeredia SánchezUnaccompanied foreign minora fact that is more complicated when it comes to adolescents. This is what is analyzed by the Judgment of the Provincial Court of BarcelonaUNESCO::CIENCIAS JURÍDICASwhich means that administrations establish a differentiated treatment for this sector of immigration due to the fact that they are minors2070-8157 22082 Revista Boliviana de Derecho 565487 2021 31 7730068 Determinación de la edad de un extranjero indocumentado A propósito de la sentencia de la audiencia provincial de barcelonamajority
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