Search results for "Mura"
showing 10 items of 356 documents
Using Machine Learning to Characterize Atrial Fibrotic Substrate From Intracardiac Signals With a Hybrid in silico and in vivo Dataset
2021
[EN] In patients with atrial fibrillation, intracardiac electrogram signal amplitude is known to decrease with increased structural tissue remodeling, referred to as fibrosis. In addition to the isolation of the pulmonary veins, fibrotic sites are considered a suitable target for catheter ablation. However, it remains an open challenge to find fibrotic areas and to differentiate their density and transmurality. This study aims to identify the volume fraction and transmurality of fibrosis in the atrial substrate. Simulated cardiac electrograms, combined with a generalized model of clinical noise, reproduce clinically measured signals. Our hybrid dataset approach combines in silico and clinic…
La «segretezza profonda» dei luoghi: Tetto Murato di Lalla Romano
2022
"Tetto Murato consisted of a group of houses, courtyards and vegetable gardens, all surrounded by a square wall. One entered through a half-collapsed arch into a maze of vegetable gardens invaded by chickens, walls and buildings''. This is how the place, around which the narrative warp of a novel was woven in 1957, takes shape in all its vivid physiognomy. The title Tetto Murato (Walled Roof) condenses its distinctive trait in the peculiar evocative concreteness of the image. The inventive dynamics of the narrative will be explored, emphasising how the space in which they unfold, the 'Roof', from the very incipit of the quoted passage, is profiled in all its protagonism. We will dwell on th…
The thermophysical characterization of technical elements in the historic architecture: experiences in Palermo
2014
Per contemperare il miglioramento delle prestazioni energetiche e ambientali dell'architettura storica con l'esigenza della sua conservazione, è necessario analizzare le caratteristiche termofisiche dei materiali e degli elementi tecnici che la connotano. Tuttavia la disponibilità di pochi dati in merito si somma alle disomogeneità tipiche della costruzione storica e alle difficoltà di analisi ad esse connesse. In particolare, per la trasmittanza termica delle murature storiche, la letteratura scientifica evidenzia scostamenti anche notevoli tra i valori desunti da misure in situ e quelli calcolati, in genere superiori ai primi. Il contributo espone gli obiettivi e la metodologia di un prog…
Regeneration of Sideritis angustifolia (Labiatae) Plants from Single Cell Cultures
1988
Summary Mechanically isolated cells from hypocotyl-derived calli of Sideritis angustifolia Lag. were inoculated on agar-solidified Murashige and Skoog (MS) nutrient medium containing CH and different concentrations and combinations of NAA and BA. Isolated cells underwent continued divisions giving rise to calli after 30 days of culture. Best results were obtained when medium was supplemented with 0.5 μM NAA and 4.4 or 8.8 μM BA or with 5 μM NAA and 4.4μM BA. Calli obtained in the presence of 0.5 μM NAA and 8.8 μM BA regenerated shoot-buds when transferred to MS medium without CH and supplemented or not with these growth regulators. Once shoots were excised, the calli maintained their morpho…
Una lettura del dato archeologico di Mura Pregne attraverso le tecnologie GIS
2012
Two master switch regulators trigger A40926 biosynthesis in Nonomuraea sp. strain ATCC 39727
2015
ABSTRACT The actinomycete Nonomuraea sp. strain ATCC 39727 produces the glycopeptide A40926, the precursor of dalbavancin. Biosynthesis of A40926 is encoded by the dbv gene cluster, which contains 37 protein-coding sequences that participate in antibiotic biosynthesis, regulation, immunity, and export. In addition to the positive regulatory protein Dbv4, the A40926-biosynthetic gene cluster encodes two additional putative regulators, Dbv3 and Dbv6. Independent mutations in these genes, combined with bioassays and liquid chromatography-mass spectrometry (LC-MS) analyses, demonstrated that Dbv3 and Dbv4 are both required for antibiotic production, while inactivation of dbv6 had no effect. In …
Sonic Hedgehog-Mediated Synergistic Effects Guiding Angiogenesis and Osteogenesis
2012
Sonic hedgehog (Shh) is a morphogen controlling the skeletal and vascular development in the embryo but is also reactivated during adult repair processes. Thus, this molecule holds great therapeutic potential for biotechnological and biomedical approaches aiming to enhance tissue regeneration or to replace damaged tissues. According to present knowledge, Shh signaling controls the expression of several families of growth factors involved in neovascularization and vessel maturation and acts upstream of the most prominent angiogenic growth factor, vascular endothelial growth factor. In this context, a very interesting feature of Shh is that it controls both angiogenic activity and vessel stab…
Radiologic and Intraoperative Finding of Intimal Tear in Type A Intramural Hematoma of the Aorta
2019
AbstractAortic intramural hematoma (IMH) is described as “dissection without intimal tear” due to rhexis of vasa vasorum, which results in bleeding within the tunica media in the absence of intimal disruption or blood flow communication. The aim of our study is to validate perioperative evidence of intimal entry tear in IMH patients and to suggest that this entity may represent a part of a disease and not a separate disease.
Evidence of intimal tear in type A intramural hematoma of the aorta: A case series
2017
Highlights • We report two cases of type A intramural hematoma of the aorta. • We found radiological and intraoperative evidence of an intimal tear. • This finding supports the hypotesis that IMH belong to “aortic dissection” disease.