Search results for "Mutagenesis"

showing 10 items of 2483 documents

Serum concentrations of persistent organic pollutants (POPs) in the inhabitants of a Sicilian city.

2012

Polychlorinated biphenyls (PCBs) and organochlorine pesticides are common environmental contaminants that have been associated with human health problems. OBJECTIVES: To assess serum concentrations of several organochlorine contaminants in general population living in a city with an ancient agricultural tradition and to identify possible exposure sources in Sicily. METHODS: A cross-sectional study was conducted on 101 individuals. Each participant answered a face-to-face questionnaire submitted by well-trained personnel and provided a serum sample which was analyzed for the concentrations of PCBs, HCB, HCHs and DDTs by using gas-chromatography coupled with mass spectrometry. RESULTS: HCB, p…

AdultMaleEnvironmental EngineeringHealth Toxicology and MutagenesisPopulationBiologySettore MED/42 - Igiene Generale E ApplicataGas Chromatography-Mass SpectrometryDDTPolychlorinated biphenylHuman healthfluids and secretionsEnvironmental healthSurveys and QuestionnairesHexachlorobenzeneHydrocarbons ChlorinatedEnvironmental ChemistryHumansCitieseducationSicilyreproductive and urinary physiologyAgedOrganochlorine contaminantsPollutantOrganochlorine pesticideeducation.field_of_studyorganic chemicalsPublic Health Environmental and Occupational HealthPesticide Residuesfood and beveragesOrganochlorine pesticideGeneral MedicineGeneral ChemistrySerum concentrationMiddle AgedPollutionPolychlorinated BiphenylsHuman biomonitoringCross-Sectional StudiesEnvironmental chemistryembryonic structuresEnvironmental PollutantsFemaleEnvironmental MonitoringChemosphere
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The 9-item Bergen Burnout Inventory: Factorial Validity Across Organizations and Measurements of Longitudinal Data

2013

The present study tested the factorial validity of the 9-item Bergen Burnout Inventory (BBI-9) 1) . The BBI-9 is comprised of three core dimensions: (1) exhaustion at work; (2) cynicism toward the meaning of work; and (3) sense of inadequacy at work. The study further investigated whether the three-factor structure of the BBI-9 remains the same across different organizations (group invariance) and measurement time points (time invariance). The factorial group invariance was tested using a cross-sectional design with data pertaining to managers (n=742), and employees working in a bank (n=162), an engineering office (n=236), a public sector organization divided into three service areas: admin…

AdultMaleFactorialLongitudinal studyFinancial ManagementLongitudinal dataHealth Toxicology and MutagenesisSample (statistics)BurnoutEngineeringSurveys and QuestionnairesStatisticsHumansBurnoutLongitudinal StudiesBurnout ProfessionalFactorial invariancePublic SectorFactor structurePublic Health Environmental and Occupational HealthReproducibility of ResultsFactorial validityMiddle AgedBergen Burnout InventoryConfirmatory factor analysisFactor invarianceCross-Sectional StudiesOrganization and AdministrationEducational StatusFemaleOriginal ArticleLongitudinal studyFactor Analysis StatisticalPsychologySocial psychologyIndustrial Health
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Predicting the Unknown and the Unknowable. Are Anthropometric Measures and Fitness Profile Associated with the Outcome of a Simulated CrossFit® Compe…

2021

The main objective of this research was to find associations between the outcome of a simulated CrossFit® competition, anthropometric measures, and standardized fitness tests. Ten experienced male CrossFit® athletes (age 28.8 ± 3.5 years

AdultMaleFunctional trainingHealth Toxicology and MutagenesisPhysical fitnesslcsh:MedicineSquatBivariate analysisBench pressArticlehigh-intensity functional training03 medical and health sciences0302 clinical medicineStatisticsHumanscross-trainingMuscle Strength030212 general & internal medicineExerciseMathematicsCross-trainingbusiness.industrylcsh:RPublic Health Environmental and Occupational Health030229 sport sciencesAnthropometryTest (assessment)functional fitnessAthletesPhysical FitnessExercise TestathletebusinessperformanceInternational Journal of Environmental Research and Public Health
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New pattern of EGFR amplification in glioblastoma and the relationship of gene copy number with gene expression profile

2010

Gene amplification is a process that is characterized by an increase in the copy number of a restricted region in a chromosome arm, and is frequently associated with an overexpression of the corresponding amplified gene. Amplified DNA can be organized either as extrachromosomal elements, repeated units at a single locus or scattered throughout the genome. The amplification of the gene for epidermal growth factor receptor (EGFR) is a common finding in glioblastomas and the amplified gene copies appears as double minutes. The aim of this study was to investigate the different patterns of EGFR amplification in 40 cases of glioblastoma using FISH analysis in metaphases and paraffin sections, an…

AdultMaleGene DosageBiologyPolymerase Chain ReactionPolymorphism Single NucleotideGene dosagePathology and Forensic MedicineYoung AdultGene expressionGene duplicationTumor Cells CulturedHumansDouble minuteRNA MessengerCopy-number variationGeneIn Situ Hybridization FluorescenceAgedOligonucleotide Array Sequence AnalysisChromosome 7 (human)Regulation of gene expressionBrain NeoplasmsGene Expression ProfilingGene AmplificationMiddle AgedImmunohistochemistryMolecular biologyErbB ReceptorsGene Expression Regulation NeoplasticMutagenesis InsertionalFemaleGlioblastomaChromosomes Human Pair 7Modern Pathology
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Hypertension and the Fat-Soluble Vitamins A, D and E

2015

Hypertension affects populations globally and is thus a public health and socio-economic problem. Macronutrient and micronutrient deficiencies are common in the general population, and may be even more prevalent in hypertensive patients. This study aimed to determine a possible association between hypertension and intake of fat-soluble vitamins A, D and E. Participants were from the cross-sectional Hortega nutrition study conducted with a random sample of 1514 people (50.3% women, 49.7% men) and two groups: nonhypertensive controls ≥40 years old (n = 429

AdultMaleGerontologyVitamineshypertensionAlcohol DrinkingCross-sectional studyHealth Toxicology and Mutagenesismedicine.medical_treatmentPopulationNutritional StatusPhysiologylcsh:MedicineArticleSurveys and QuestionnairesVitamin D and neurologyHumansVitamin EMedicineVitamin DVitamin AeducationNutricióAgedMineralseducation.field_of_studybusiness.industryVitamin ESmokinglcsh:RPublic Health Environmental and Occupational Healthfat-soluble vitaminVitaminsnutritional deficiencyMiddle AgedAnthropometryNutrition SurveysMicronutrientDietCross-Sectional StudiesFat-Soluble VitaminSocial ClassFemaleAnalysis of variancebusinessInternational Journal of Environmental Research and Public Health
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Socio-Demographic Characteristics and Sexual Behavioral Factors of Patients with Sexually Transmitted Infections Attending a Hospital in Southern Ita…

2021

Sexually transmitted infections (STIs) are a serious global health problem. In Italy, data describing the vulnerability to STIs of specific sexual minorities and the influence of sociodemographic and behavioral determinants are limited, as most infections are not subject to mandatory notification. This retrospective study describes the sociodemographic profile and main sexual behaviors of patients attending a hospital in Palermo (Sicily, Italy) from January 2018 to March 2019 as predictors of STI risk. Patients were divided in subgroups: men-who-have-sex-with-men (MSM), men-who-have-sex-with-women (MSW), bisexual men and females. Data were obtained through an anonymous questionnaire. Patien…

AdultMaleHPVSexual BehaviorHealth Toxicology and MutagenesisSocio demographicsSexually Transmitted DiseasessyphilisHIV InfectionsMycoplasma genitaliumSTIsArticleSexual and Gender Minorities03 medical and health sciences0302 clinical medicineRisk FactorsmedicineGlobal healthHumansMycoplasma Infections030212 general & internal medicineMSMHomosexuality MaleSicilyDemographyRetrospective Studiesbehaviour risky factors HPV MSM STIs syphilis030505 public healthChlamydiabiologybusiness.industrybehaviour risky factorsPublic Health Environmental and Occupational HealthHPV infectionRvirus diseasesRetrospective cohort studymedicine.diseasebiology.organism_classificationHospitalsSexual PartnersSexual behaviorMedicineFemaleSyphilis0305 other medical sciencebusinessMycoplasma genitaliumDemography
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Italian Health Care Workers’ Knowledge, Attitudes, and Practices Regarding Human Papillomavirus Infection and Prevention

2020

Objective: To assess healthcare workers&rsquo

AdultMaleHealth Knowledge Attitudes Practicemedicine.medical_specialtyHPVknowledgegenetic structuresHealth PersonnelHealth Toxicology and MutagenesisUterine Cervical Neoplasmslcsh:MedicineScientific literatureimmunizationSettore MED/42 - Igiene Generale E ApplicataArticle03 medical and health sciences0302 clinical medicinepreventionAttitude Awareness Healthcare workers HPV Immunization Knowledge Practice Prevention Sexually transmitted infection Adult Cross-Sectional Studies Female Italy Middle Aged Papillomavirus Vaccines Papillomavirus Infections Uterine Cervical NeoplasmsSurveys and QuestionnairesvaccineIntervention (counseling)Health caremedicineHumansAttitude; Awareness; Healthcare workers; HPV; Immunization; Knowledge; Practice; Prevention; Sexually transmitted infection; VaccineawarenessPapillomavirus Vaccinessexually transmitted infection030212 general & internal medicineHuman papillomavirusbusiness.industryhealthcare workersPapillomavirus Infectionslcsh:RPublic Health Environmental and Occupational HealthMiddle AgedProduct characteristicspracticeCross-Sectional StudiesItaly030220 oncology & carcinogenesisFamily medicineattitudeMulticenter surveyPropensity score matchingFemalebusinessInternational Journal of Environmental Research and Public Health
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Envy and Counterproductive Work Behavior: The Moderation Role of Leadership in Public and Private Organizations

2018

Envy is a frequent emotion in work contexts where there is strong competition for resources and the leader is the person who manages them. When employees feel envy, they are likely to use counterproductive work behaviors (CWB), but the use of these behaviors may differ depending on the organization&rsquo

AdultMaleHealth Toxicology and MutagenesisEmotionslcsh:Medicine050109 social psychologyhealthy organizationsArticleEmpirical research0502 economics and businessHumans0501 psychology and cognitive sciencesPath analysis (statistics)Social BehaviorWorkplacePractical implicationscounterproductive work behaviorOrganizations05 social scienceslcsh:RPublic Health Environmental and Occupational HealthMiddle AgedModerationLeadershipleader-member exchangepublic/private organizationsSocial exchange theoryenvyFemalePsychologyCounterproductive work behaviorSocial psychology050203 business & managementInternational Journal of Environmental Research and Public Health
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Validation of TMMS-24 in Three Spanish-Speaking Countries: Argentina, Ecuador, and Spain

2021

Emotional intelligence (EI) is a fundamental skill related to different aspects of human life, such as psychological well-being or mood states. The present study has a triple objective: first, to explore the psychometric properties of the TMMS-24 in three Spanish-speaking countries (Argentina, Ecuador, and Spain)

AdultMaleHealth Toxicology and MutagenesisHuman lifemoodArgentinaSample (statistics)Spanish speakingemotional intelligenceArticleYoung AdultHumansintergroup relations//purl.org/becyt/ford/5.1 [https]LanguagevalidationTMMS-24//purl.org/becyt/ford/5 [https]Emotional intelligencePublic Health Environmental and Occupational HealthRSampling (statistics)MoodSpainMedicineFemaleEcuadorPsychologyClinical psychology
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Analysis of Performance Parameters of the Smash in Male and Female Professional Padel

2020

The aim of this study was to analyze the distribution and effectiveness of the different types of smash in professional padel according to the area and direction of the strokes and the gender. Through systematic observation, 1.015 smashes from eight finals (four men&rsquo

AdultMaleHealth Toxicology and MutagenesisMovementracket sportstacticslcsh:MedicineAthletic PerformanceArticle03 medical and health sciences0302 clinical medicineSex FactorsStatisticsTask Performance and AnalysisHumans030212 general & internal medicineperformance analysisMathematicslcsh:RPublic Health Environmental and Occupational HealthRacquet Sports030229 sport sciencestechniqueMotor SkillsFemaleLine (text file)International Journal of Environmental Research and Public Health
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