Search results for "N.I.H."

showing 10 items of 2860 documents

Asymmetric Vinylogous Mannich-Type Addition of α,α-Dicyanoalkenes to α-Fluoroalkyl Sulfinyl Imines

2018

Abstract. The asymmetric vinylogous Mannich reaction (AVMR) of alfa,alfa-dicyanoalkenes with alfa-fluoroalkyl sulfinyl imines has been successfully accomplished. This transformation is unprecedented with fluorinated imines at the same time as the use of dicyanoalkenes in AVMR has been scarcely reported. Several fluorinated sulfinyl imines are compatible with the process, which gaves access to a family of chiral fluorinated amines with excellent level of stereocontrol. Interestingly, the selectivity found in our protocol is reverse to that encountered in analogous AVMR previously reported. Additionally, the synthetic applicability of the addition products has been exemplified with several tr…

010405 organic chemistryStereochemistryChemistryMoietyReactivity (chemistry)General Chemistry010402 general chemistrySelectivity01 natural sciencesMedicinal chemistryMannich reaction0104 chemical sciencesAdvanced Synthesis & Catalysis
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Organocatalytic Asymmetric Synthesis of 2,3′-Connected Bis-Indolinones by Mannich Reactions of N-Acetylindolin-3-ones with Isatin N-Boc Ketimines

2017

A highly diastereo- and enantioselective Mannich reaction of N-acetylindolin-3-ones with isatin N-Boc ketimines to form 2,3′-connected bis-indolinones is developed employing a low loading of a readily available bifunctional thiourea catalyst. The asymmetric synthesis connects two indolinones via a vic-diamine unit and generates two neighboring stereocenters.

010405 organic chemistryStereochemistryIsatinOrganic ChemistryEnantioselective synthesis010402 general chemistry01 natural sciencesMedicinal chemistryCatalysis0104 chemical sciencesStereocenterchemistry.chemical_compoundchemistryThioureaOrganocatalysisDiamineBifunctionalMannich reactionSynthesis
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Ray optics for absorbing particles with application to ice crystals at near-infrared wavelengths

2018

Abstract Light scattering by particles large compared to the wavelength of incident light is traditionally solved using ray optics which considers absorption inside the particle approximately, along the ray paths. To study the effects rising from this simplification, we have updated the ray-optics code SIRIS to take into account the propagation of light as inhomogeneous plane waves inside an absorbing particle. We investigate the impact of this correction on traditional ray-optics computations in the example case of light scattering by ice crystals through the extended near-infrared (NIR) wavelength regime. In this spectral range, ice changes from nearly transparent to opaque, and therefore…

010504 meteorology & atmospheric sciencesOpacityspektroskopiaIce crystalsPhysics::OpticsRay optics01 natural sciencesPOLARIZED-LIGHT SCATTERING114 Physical sciencesLight scattering010309 opticsScatteringMEDIAOptics0103 physical sciencesABSORPTIONInhomogeneous wavesCIRRUSray opticsSpectroscopy0105 earth and related environmental sciencesPhysicsta113absorbing mediaRadiationta115Geometrical opticsIce crystalsta114Scatteringbusiness.industryscatteringCLOUDSkiteetRayAtomic and Molecular Physics and OpticsoptiikkaSOLAR-RADIATIONWavelengthMAXWELLS EQUATIONSAbsorbing mediainhomogeneous wavesLight scattering by particlesPHASE MATRIXGEOMETRIC-OPTICSbusinessice crystalsAPPROXIMATION
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Rare earth element and neodymium isotope tracing of sedimentary rock weathering

2020

Chemical weathering plays an important role in sequestering atmospheric CO2, but its potential influence on global climate over geological timescales remains debated. To some extent, this uncertainty arises from the difficulty in separating the respective contribution of sedimentary and crystalline silicate rocks to past weathering rates in the geological record; two types of rocks having presumably different impact on the long-term carbon cycle. In this study, we investigate the use of rare earth element (REE) and neodymium isotopes (εNd) in leached iron oxide fractions of river sediments for tracing the origin of weathered rocks on continents. A new index, called ‘concavity index’ (CI), i…

010504 meteorology & atmospheric sciencessub-01Mid-REE enrichmentGeochemistrySilicate weatheringWeatheringConcavity indexengineering.materialStructural basin010502 geochemistry & geophysicsGeologic record01 natural sciencesIron oxideschemistry.chemical_compoundGeochemistry and Petrology[SDU.STU.GC]Sciences of the Universe [physics]/Earth Sciences/Geochemistry[CHIM]Chemical Sciences0105 earth and related environmental sciencesgeographygeography.geographical_feature_categorySulphide weatheringNeodymium isotopesGeology15. Life on landWorld riversSilicateCratonchemistry13. Climate actionCarbonate weatheringengineeringCarbonateSedimentary rockPyriteGeology
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Effect of addition of Opuntia ficus-indica mucilage on the biological leavening, physical, nutritional, antioxidant and sensory aspects of bread

2019

The addition of active compounds to enhance the functional properties of foods is a quite common practice. Recently, bread became one of the target foods to incorporate functional ingredients such as those deriving from Opuntia spp. So far, only Opuntia ficus-indica cladodes in powder has been tested. The addition of fresh O. ficus-indica mucilage (in substitution to water) did not influence the biological leavening of the doughs. The resulting breads showed a biological role of the cactus mucilage, because their antioxidant activity was higher than that of control wheat bread. The sensory analysis indicated a general appreciation of the breads enriched with O. ficus-indica mucilage by the …

0106 biological sciences0301 basic medicineAntioxidantmedicine.medical_treatmentOpuntia ficusBioengineeringAntimicrobial activity01 natural sciencesApplied Microbiology and BiotechnologySensory analysisAntioxidantsCactus mucilage03 medical and health sciencesAntioxidant activityPolysaccharidesYeasts010608 biotechnologymedicineCladodesFood scienceEnriched breadLeavening agentBiological leaveningbiologyPlant Extractsdigestive oral and skin physiologyOpuntiafood and beveragesBreadbiology.organism_classification030104 developmental biologyMucilageCactusDietary antioxidantBiotechnologyJournal of Bioscience and Bioengineering
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Ultraviolet radiation accelerates photodegradation under controlled conditions but slows the decomposition of senescent leaves from forest stands in …

2019

Depending on the environment, sunlight can positively or negatively affect litter decomposition, through the ensemble of direct and indirect processes constituting photodegradation. Which of these processes predominate depends on the ecosystem studied and on the spectral composition of sunlight received. To examine the relevance of photodegradation for litter decomposition in forest understoreys, we filtered ultraviolet radiation (UV) and blue light from leaves of Fagus sylvatica and Bettda pendula at two different stages of senescence in both a controlled-environment experiment and outdoors in four different forest stands (Picea abies, Pagus sylvatica, Acer platanoides, Betula pendula). Co…

0106 biological sciences0301 basic medicineCanopyUltraviolet RaysPhysiologyUV-B RADIATIONPlant ScienceForestsANTHOCYANINS01 natural sciencesUV radiationBOREAL FOREST03 medical and health scienceschemistry.chemical_compoundFagus sylvaticaPhotodegradationGeneticsPhotodegradationEcosystemFinlandComputingMilieux_MISCELLANEOUS11832 Microbiology and virologyFlavonoidsSunlight[SDV.EE]Life Sciences [q-bio]/Ecology environment4112 ForestryPhotolysisbiologyChemistryTEMPERATEPLANT LITTERPicea abies15. Life on landPlant litterbiology.organism_classificationPhenolic compoundsUnderstorey light environmentSODANKYLAPlant LeavesHorticultureLIGHT030104 developmental biology13. Climate actionBetula pendulaChlorophyllPATTERNS1182 Biochemistry cell and molecular biologyLEAF-LITTER DECOMPOSITION010606 plant biology & botany
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Adaptive Evolution and Epigenetics

2023

Epigenetic changes, such as DNA methylation and certain histone modifications, can be inherited but in many cases they do not follow Mendelian inheritance patterns and their stability appears to be lower than for changes in DNA sequence. Adaptive evolution by natural selection requires that differences among individuals are heritable to some degree. Epigenetic changes can be incorporated into evolutionary theory, and given that properties of epigenetic variation are distinct from genetic variation, spontaneous epigenetic changes can affect evolutionary dynamics in interesting ways. In this chapter, I review the properties of epigenetic variation and how they relate to the main parameters of…

0106 biological sciences0301 basic medicineGeneticseducation.field_of_studyNatural selectionPopulationBiology010603 evolutionary biology01 natural sciences03 medical and health sciencessymbols.namesake030104 developmental biologyEvolutionary biologyGenetic variationDNA methylationMendelian inheritancesymbolssense organsEpigeneticsAdaptationEvolutionary dynamicseducation
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Volatile organic compounds in wild fungi from Mediterranean forest ecosystems

2017

AbstractHead Space-Solid Phase Micro Extraction (HS-SPME) extractions and Gas Chromatography-Mass Spectrometry (GC-MS) analysis allowed the identification of 72 different compounds isolated from 7 different wild inedible fungi collected in Mediterranean forest ecosystems. The VOCs reported in this study, including a total of 5 esters, 17 alcohols, 14 aldehydes, 9 ketones, 18 terpenes and 9 other compounds, have been never characterized before for Tricholoma ustaloides, Hygrophorus cossus, Russula foetens and Mycena pura.

0106 biological sciences0301 basic medicineMediterranean climatevolatile organic compoundTricholoma ustaloidesSettore AGR/13 - Chimica AgrariaBiodiversityBiology01 natural sciencesMediterranean areaTerpene03 medical and health sciencesForest ecologyBotanyHS-SPMEbiodiversitySettore BIO/02 - Botanica SistematicaExtraction (chemistry)Chemistry (all)General Chemistry030108 mycology & parasitologybiology.organism_classificationEnvironmental chemistryMycena puraBasidiomycetefungiHygrophorus cossus010606 plant biology & botany
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Angiosperm to Gymnosperm host-plant switch entails shifts in microbiota of the Welwitschia bug, Probergrothius angolensis (Distant, 1902).

2019

The adaptation of herbivorous insects to new host plants is key to their evolutionary success in diverse environments. Many insects are associated with mutualistic gut bacteria that contribute to the host's nutrition and can thereby facilitate dietary switching in polyphagous insects. However, how gut microbial communities differ between populations of the same species that feed on different host plants remains poorly understood. Most species of Pyrrhocoridae (Hemiptera: Heteroptera) are specialist seed-feeders on plants in the family Malvaceae, although populations of one species, Probergrothius angolensis, have switched to the very distantly related Welwitschia mirabilis plant in the Nami…

0106 biological sciences0301 basic medicinemedia_common.quotation_subjectZoologyInsect010603 evolutionary biology01 natural sciencesHeteroptera03 medical and health sciencesMagnoliopsidaGymnospermGeneticsAnimalsHerbivorySymbiosisEcology Evolution Behavior and Systematicsmedia_commonbiologyBacteriaHost (biology)Probergrothius angolensisMicrobiotafungiHeteropteraWelwitschiafood and beveragesbiology.organism_classificationHemipteraBiological EvolutionGastrointestinal Microbiome030104 developmental biologyCycadopsidaAdaptationMolecular ecologyREFERENCES
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Protein hydrolysates and mo-biofortification interactively modulate plant performance and quality of ‘canasta’ lettuce grown in a protected environme…

2021

Since the use of protein hydrolysates (PHs) enhances overall plant performance and quality of vegetables, they might be considered as a toll to face a number of concerns essentially associated to the growing request of premium quality foodstuff realized in agreement with eco-friendly agriculture practices. Molybdenum (Mo) is considered a fundamental trace element for human body. Thus, its shortage determines several disorders mainly related to neurological lesion and esophageal cancer. Biofortification of fruiting and leafy vegetables is a promising tool to prevent Mo deficiency in the human diet. The current study was carried out to assess the interactive effect of plant-derived PHs and Mo…

0106 biological sciences<i>Lactuca sativa</i> L.Biofortificationchemistry.chemical_elementPlant-derived PHsSettore AGR/04 - Orticoltura E Floricolturanitrogen indicesnutritional traitsNitrogen indice01 natural scienceschemistry.chemical_compoundNutritional traitSoluble solidsLactuca sativa LFood scienceProtein hydrolysatesCarotenoidchemistry.chemical_classificationSMolybdenum-enrichmentplant-based biostimulantsAgriculture04 agricultural and veterinary sciencesAscorbic acidNitrogenFunctional qualityPlant-based biostimulantchemistryChlorophyll040103 agronomy & agriculture0401 agriculture forestry and fisheriesLactuca sativa L.Leafy vegetablesAgronomy and Crop ScienceBiofortification010606 plant biology & botany
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