Search results for "NAPS"
showing 10 items of 302 documents
Recent Advances in Techniques for Hyperspectral Image Processing
2009
International audience; Imaging spectroscopy, also known as hyperspectral imaging, has been transformed in less than thirty years from being a sparse research tool into a commodity product available to a broad user community. Currently, there is a need for standardized data processing techniques able to take into account the special properties of hyperspec- tral data. In this paper, we provide a seminal view on recent advances in techniques for hyperspectral image processing. Our main focus is on the design of techniques able to deal with the high-dimensional nature of the data, and to integrate the spa- tial and spectral information. Performance of the discussed techniques is evaluated in …
Eucynodont teeth from the Late Triassic of Krasiejów, Southern Poland
2021
Recent discoveries of Mammaliamorph teeth in the Keuper of southern Poland have extended the global record of eucynodonts in the Late Triassic and revealed a significant diversity of the group at that time. Here,we expand on this record with the description of new cynodont postcanine teeth from the Krasiejów bone bed. They show the dental morphology typical for Dromatheriidae, with a single root and crown without cingulum. We assigned them to Polonodon woznikensis, described from Woźniki. None of the 38 teeth from Krasiejów and Woźniki exhibit signs of serious wear, potentially indicating a very fast rate of tooth replacement in Polonodon.
Stabilized branch-and-price algorithms for vector packing problems
2018
Abstract This paper considers packing and cutting problems in which a packing/cutting pattern is constrained independently in two or more dimensions. Examples are restrictions with respect to weight, length, and value. We present branch-and-price algorithms to solve these vector packing problems (VPPs) exactly. The underlying column-generation procedure uses an extended master program that is stabilized by (deep) dual-optimal inequalities. While some inequalities are added to the master program right from the beginning (static version), other violated dual-optimal inequalities are added dynamically. The column-generation subproblem is a multidimensional knapsack problem, either binary, boun…
Learning automata-based solutions to the optimal web polling problem modelled as a nonlinear fractional knapsack problem
2011
We consider the problem of polling web pages as a strategy for monitoring the world wide web. The problem consists of repeatedly polling a selection of web pages so that changes that occur over time are detected. In particular, we consider the case where we are constrained to poll a maximum number of web pages per unit of time, and this constraint is typically dictated by the governing communication bandwidth, and by the speed limitations associated with the processing. Since only a fraction of the web pages can be polled within a given unit of time, the issue at stake is one of determining which web pages are to be polled, and we attempt to do it in a manner that maximizes the number of ch…
AMPA receptor complex constituents: Control of receptor assembly, membrane trafficking and subcellular localization
2018
Fast excitatory transmission at synapses of the central nervous system is mainly mediated by AMPA receptors (AMPARs). Synaptic AMPAR number and function correlates with synaptic strength. AMPARs are thus key proteins of activity-dependent plasticity in neuronal communication. Up- or down-regulation of synaptic AMPAR number is a tightly controlled dynamic process that involves export of receptors from the endoplasmic reticulum (ER) and Golgi apparatus, exocytosis and endocytosis as well as lateral diffusion of the receptors in the cell membrane. The four AMPAR subunits are embedded into a dynamic network of more than 30 interacting proteins. Many of these proteins are known to modulate recep…
Dysregulated genes and their functional pathways in luteinized granulosa cells from PCOS patients after cabergoline treatment
2018
Polycystic ovarian syndrome (PCOS) is a common reproductive disorder frequently associated with a substantial risk factor for ovarian hyperstimulation syndrome (OHSS). Dopamine receptor 2 (D2) agonists, like cabergoline (Cb2), have been used to reduce the OHSS risk. However, lutein granulosa cells (LGCs) from PCOS patients treated with Cb2 still show a deregulated dopaminergic tone (decreased D2 expression and low dopamine production) and increased vascularization compared to non-PCOS LGCs. Therefore, to understand the PCOS ovarian physiology, it is important to explore the mechanisms that underlie syndrome based on the therapeutic effects of Cb2. Here, LGCs from non-PCOS and PCOS patients …
Secukinumab efficacy in the treatment of nail psoriasis: a case series
2018
Nail involvement is frequent in patients with psoriasis, especially those with psoriatic arthritis (PsA), and can significantly impair quality of life (QoL). It is typically difficult to treat compared with skin lesions, although several conventional treatment options are available. The aim of this article is to describe our experience in the treatment of nail psoriasis with secukinumab in a case series. Fifteen patients (11 males and 4 females), with moderate-severe plaque psoriasis and nail psoriasis, eligible for systemic therapy, and received secukinumab. The Psoriasis Area and Severity Index (PASI) and body surface area (BSA) assessed cutaneous severity. Nail Psoriasis Severity Index (…
IGF-1 Haploinsufficiency Causes Age-Related Chronic Cochlear Inflammation and Increases Noise-Induced Hearing Loss
2021
This article belongs to the Collection Insulin-Like Growth Factors in Development, Cancers and Aging.
Dendritic and Axonal L-Type Calcium Channels Cooperate to Enhance Motoneuron Firing Output during Drosophila Larval Locomotion
2017
Behaviorally adequate neuronal firing patterns are critically dependent on the specific types of ion channel expressed and on their subcellular localization. This study combinesin situelectrophysiology with genetic and pharmacological intervention in larvalDrosophila melanogasterof both sexes to address localization and function of L-type like calcium channels in motoneurons. We demonstrate that Dmca1D (Cav1 homolog) L-type like calcium channels localize to both the somatodendritic and the axonal compartment of larval crawling motoneurons.In situpatch-clamp recordings in genetic mosaics reveal that Dmca1D channels increase burst duration and maximum intraburst firing frequencies during craw…
Localization of the cannabinoid type-1 receptor in subcellular astrocyte compartments of mutant mouse hippocampus
2018
Astroglial type‐1 cannabinoid (CB1) receptors are involved in synaptic transmission, plasticity and behavior by interfering with the so‐called tripartite synapse formed by pre‐ and post‐synaptic neuronal elements and surrounding astrocyte processes. However, little is known concerning the subcellular distribution of astroglial CB1 receptors. In particular, brain CB1 receptors are mostly localized at cells' plasmalemma, but recent evidence indicates their functional presence in mitochondrial membranes. Whether CB1 receptors are present in astroglial mitochondria has remained unknown. To investigate this issue, we included conditional knock‐out mice lacking astroglial CB1 receptor expression …