Search results for "NASAL"
showing 10 items of 426 documents
High Flow Nasal Therapy Use in Patients with Acute Exacerbation of COPD and Bronchiectasis: A Feasibility Study
2020
The efficacy and feasibility of high flow nasal therapy (HFNT) use in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and bronchiectasis is unknown. We performed a single-center, single-arm prospective observational study in patients with AECOPD, documented bronchiectasis, pH >= 7.35, respiratory rate (RR) >= 26 breaths/minute despite receiving maximal medical treatment and oxygen via face mask up to 10 L/m. Patients received HFNT (Airvo 2, Fisher & Paykel) at a gas flow of 50 L/min and FIO2 adjusted to maintain SpO(2) >= 92%. Dyspnea, rated by Borg scale, RR, arterial blood gases and mucus production (ranging from 1 to 3) were collected befor…
Rhinomanometry: point of care test (POCT) for allergic rhinitis in children?
2021
Allergic rhinitis (AR) is a global health problem: its prevalence is 23% in Europe, although it is underestimated because as many as 45% of the cases remain undiagnosed. Globally, almost 500 million people suffer from AR, which shows its increasing incidences. The diagnostic course of AR is based on clinical history, supported by anterior rhinoscopy. This inspects the anterior part of the nasal cavity accompanied by allergic sensitivity tests (cutaneous allergic skin tests or specific immunoglobulin E levels). The availability of standardised diagnostic proceduresis able to provide objective evaluations of inflammatory situation, and the degree of nasal obstruction may give an advantage in …
[Nasal and bronchial provocation with allergen in patients with mild asthma and allergic rhinitis -- similarities and differences].
2005
The right interface for the right patient in noninvasive ventilation: a systematic review
2022
Introduction Research in the field of noninvasive ventilation (NIV) has contributed to the development of new NIV interfaces. However, interface tolerance plays a crucial role in determining the beneficial effects of NIV therapy. Areas covered This systematic review explores the most significant scientific research on NIV interfaces, with a focus on the potential impact that their design might have on treatment adherence and clinical outcomes. The rationale on the choice of the right interface among the wide variety of devices that are currently available is discussed here. Expert opinion The paradigm 'The right mask for the right patient' seems to be difficult to achieve in real life. Rang…
Accuracy of Nasal Pressure Swing to Predict Failure of High-Flow Nasal Oxygen in Patients with Acute Hypoxemic Respiratory Failure
2023
In a real-life cohort of patients with AHRF undergoing HFNO, ΔPnose showed excellent accuracy in predicting early failure, similar of that displayed by ROX. Giving that the decision to upgrade to NIV or MV was based on clinical variables, the high accuracy of ROX in predicting failure of HFNO is not surprising. The similar accuracy of ΔPnose (the only measurement that remained blinded to our clinical decision), strengthened the association with outcome, avoiding incorporation bias.
Una Nueva Técnica de Remodelación de la Punta Nasal en Rinoplastia, para Casos Extremadamente Difíciles, Mediante la Resección Total de los Cartílago…
2015
Leonardo Da Vinci solía decir que: “La nariz está ahí para manifestar el carácter del rostro”. Y ya en el s. XX, Jack Sheen afirmó con rotundidad: “La Rinoplastia es una operación tremendamente difícil aunque técnicamente resulte decepcionantemente fácil”. La Rinoplastia es una de las operaciones más frecuentes en Cirugía Plástica, es la más difícil, creativa, artística, estudiada, debatida, controvertida, apasionante y siempre fascinante. Y la parte más difícil de abordar con éxito en una rinoplastia es la Punta. Presentamos una Nueva Técnica de Remodelación de la Punta Nasal en Rinoplastia, para Casos Extremadamente Difíciles, Mediante la Resección Total de los Cartílagos Alares y Fascia …
Molecular and Clinical Predictors of Quality of Life in Chronic Rhinosinusitis with Nasal Polyps
2023
(1) Background: Factors influencing the quality of life (QoL) of patients with chronic rhinosinusitis with nasal polyposis (CRSwNP) are poorly understood. We set out to determine the predictive factors on patients’ QoL using the Sino-Nasal Outcome Test-22 (SNOT-22); (2) Methods: An ambispective analysis of data from patients diagnosed with CRSwNP in our institution. All the patients underwent a nasal polyp biopsy and completed the SNOT-22 questionnaire. Demographic and molecular data as well as the SNOT-22 scores were collected. Patients were classified in six subgroups considering the presence of asthma, non-steroidal drugs (NSAID) intolerance and corticosteroid resistance; (3) Results: Th…
Meta-analysis of the objective and subjective evaluation of nasal surgery
2021
Priekšvēsture: Nav vienota viedokļa par objektīvu un subjektīvu novērtēšanas metožu lietderību deguna elpceļu obstrukcijas novērtēšanā un ārstēšanas ietekmi uz dzīves kvalitāti, saistībā ar deguna operācijām. Mērķis: Metaanalīžu mērķis bija novērtēt korelāciju starp mūsdienīgu objektīvo mērījumu un subjektīvo deguna obstrukcijas sajūtu, kas ietekmē deguna elpceļus pēc deguna operācijas. Materiāli un metodes: Tika veikta sistemātiska literatūras analīze no zinātniskiem rakstiem angļu valodā, kuros tika apskatīta korelācija starp objektīviem mērījumiem un subjektīviem deguna elpceļu obstrukcijas simptomiem pēcoperatīvajā periodā. Pētījuma autore veica 23 zinātnisko rakstu analīzi. Pētījuma re…
Resection of verrucous squamous cell carcinoma of the nasal cavity using advanced radiofrequency
2008
Regulatory T cells selectively preserve immune privilege of self-antigens during viral central nervous system infection.
2012
Abstract Regulatory T cells (Tregs) are important for the attenuation of immune reactions. During viral CNS infections, however, an indiscriminate maintenance of CNS immune privilege through Treg-mediated negative regulation could prevent autoimmune sequelae but impair the control of viral replication. We analyzed in this study the impact of Tregs on the development of acute viral encephalomyelitis, T cell-mediated antiviral protection, and prevention of CNS autoimmunity following intranasal infection with the gliatropic mouse hepatitis virus strain A59. To assess the contribution of Tregs in vivo, we specifically depleted CD4+Foxp3+ T cells in a diphtheria toxin-dependent manner. We found …