Search results for "NGF"
showing 10 items of 97 documents
Rethinking visual art practice in relation to well-being : a conceptual analysis
2015
This study examines how the concepts related to visual art practice and well-being have been used in the arts and academic sectors. Furthermore, it studies whether it is possible to create a new theoretical and conceptual framework for research. The research material of the arts and academic sectors was examined by the methods of critical review and conceptual analysis. The conceptual analysis led to the following main results: The employment of the concepts concerning the practice of visual arts was diverse, often overlapping, and in some respects incoherent. Both the concepts of ‘art’ and ‘well-being’ were mostly used as reasoning with generalizations. This strategy of discourse was conce…
Physiotherapists’ experiences of direct access for clients with musculoskeletal pain and dysfunction: a qualitative study
2019
Aims: The aim of this study was to qualitatively analyse physiotherapists’ experiences and perspectives for delivering services directly, without prescription or referral, for clients with musculoskeletal pain or dysfunction. Methods: This was a qualitative study where data were collected from questionnaires given to 34 physiotherapists, 18 of them being in direct access for 6 years and 16 for 6 months. There were 15 structured questions and 3 open-ended ones. The answers were analysed with quantitative and qualitative methods. Results: The data analysis of the open-ended questions showed that physiotherapists had positive experiences of direct access. This practice brought meaningfulness, …
Hobby, career or vocation? Meanings in sports coaching and their implications for recruitment and retention of coaches
2020
Rationale/Purpose: Traditional European sports clubs are facing increasing pressures to professionalise their services, while also encountering difficulties in the recruitment and retention of the coaching workforce. We used the concept of meaningful work to explore why coaching is worthwhile to coaches and how they have responded to the changes in the structural and narrative context of their work. \ud \ud Methodology: Drawing on narrative inquiry, we explored the various meanings and justifications that athletics (track and field) coaches assign to coaching in Finland and England. Twenty-three coaches (8 women, 15 men) aged 22 – 86 participated in narrative interviews that were analysed u…
Everyday Life Meaningfulness for the Community-Dwelling Oldest Old During the COVID-19 Pandemic
2021
In many countries, the COVID-19 pandemic has led to strong restrictions and changed the everyday lives of older people. In Finland, people aged 70 and over were instructed to stay at home under quarantine-like conditions. Existing studies from other countries have reported increases in negative experiences and symptoms as a result of such restrictions, including psychosocial stress. However, little focus has been given to older people’s experiences of meaningfulness during the pandemic. Using survey and interview data, we ask to what extent have community-dwelling oldest old (80+) experienced meaningfulness during the pandemic, what background factors are associated with meaningfulness and …
Towards dialogic teaching in science : challenging classroom realities through teacher education
2013
Meaningful learning in teacher education
2018
This study explores meaningful learning in the context of teacher education. The study showed the importance of course design in generating meaningful learning. Opportunities to gain strong experience are crucial to meaningful learning. Meaningful learning provides space for both positive and uncomfortable emotions. peerReviewed
Debating "the ABCs of parliamentary life" : the learning of parliamentary rules and practices in the late nineteenth-century Finnish Diet and the ear…
2014
Tiam1 as a Signaling Mediator of Nerve Growth Factor-Dependent Neurite Outgrowth
2010
Nerve Growth Factor (NGF)-induced neuronal differentiation requires the activation of members of the Rho family of small GTPases. However, the molecular mechanisms through which NGF regulates cytoskeletal changes and neurite outgrowth are not totally understood. In this work, we identify the Rac1-specific guanine exchange factor (GEF) Tiam1 as a novel mediator of NGF/TrkA-dependent neurite elongation. In particular, we report that knockdown of Tiam1 causes a significant reduction in Rac1 activity and neurite outgrowth induced by NGF. Physical interaction between Tiam1 and active Ras (Ras- GTP), but not tyrosine phosphorylation of Tiam1, plays a central role in Rac1 activation by NGF. In add…
Condotta di singoli organi e condotta dell’apparato statale in tema di colpa nell’illecito internazionale
1988
In questo scritto si dimostra che l'elemento della colpa nell'illecito internazionale (inteso come "colpevolezza") è difficilmente compatibile con la struttura complessa dell'organizzazione dello Stato contemporaneo. La dimostrazione è essenzialmente condotta con riferimento alla giurisprudenza della Corte di giustizia delle comunità europee in tema di violazione dei trattati o di regolamenti da parte degli Stati. Viene altresì sottolineato che un tale risultato è in linea con l'evanescenza delle cause di invalidità dei trattati concernenti la volontà di singoli organi partecipanti al processo di stipulazione. The idea is advanced that state fault - understood as an essential precondition f…
Social Participation Considered as Meaningful in old age − the Perceptions of Senior Housing Residents in Finland
2023
AbstractAs populations across the world age, there is a recognised need for promoting social participation in older adults. Previous studies related to social participation have addressed that interactions perceived as meaningful may improve quality of life in old age. However, what is less clear is the nature of such participation from the perspective of older adults, as the vast majority of studies have been quantitative. The present study aimed to explore what characterises social participation that contributes to a meaningful everyday life, from the viewpoint of independently living Finnish older adults. Thematic analysis was used as an interpretative method drawing on semi-structured i…