Search results for "NLS"
showing 10 items of 31 documents
Improved Active Disturbance Rejection Control for Trajectory Tracking Control of Lower Limb Robotic Rehabilitation Exoskeleton.
2020
Neurological disorders such as cerebral paralysis, spinal cord injuries[acronym](SCI), and strokes, result in the impairment of motor control and induce functional difficulties to human beings like walking, standing, etc. Physical injuries due to accidents and muscular weaknesses caused by aging [english]affectsaffect people and can cause them to lose their ability to perform daily routine functions. In order to help people recover or improve their dysfunctional activities and quality of life after accidents or strokes, assistive devices like exoskeletons and orthoses are developed. Control strategies for control of exoskeletons are developed with the desired intention of improving the qual…
Identification of a classic nuclear localization signal at the N terminus that regulates the subcellular localization of Rbfox2 isoforms during diffe…
2016
Nuclear localization of the alternative splicing factor Rbfox2 is achieved by a C-terminal nuclear localization signal (NLS) which can be excluded from some Rbfox2 isoforms by alternative splicing. While this predicts nuclear and cytoplasmic localization, Rbfox2 is exclusively nuclear in some cell types. Here, we identify a second NLS in the N terminus of Rbfox2 isoform 1A that is not included in Rbfox2 isoform 1F. Rbfox2 1A isoforms lacking the C-terminal NLS are nuclear, whereas equivalent 1F isoforms are cytoplasmic. A shift in Rbfox2 expression toward cytoplasmic 1F isoforms occurs during epithelial to mesenchymal transition (EMT) and could be important in regulating the activity and fu…
Differential subcellular expression of P525LFUS as a putative biomarker for ALS phenoconversion
2020
P525LFused-in-Sarcoma ( FUS ) mutation is associated with a specific amyotrophic lateral sclerosis (ALS) phenotype characterized by a juvenile-onset and a severe course.1 This harmful point mutation is located in the nuclear localization signal (NLS) domain at the protein C-terminal.2 Although wild-type FUS protein is expressed almost exclusively in the nucleus, the P525L FUS mutation leads to a protein mislocalization into the cytoplasm3,4 because of its loss of capacity to bind its transporter karyopherin-2 and to be transferred back to the nucleus.3
Dissection of human papillomavirus type 33 L2 domains involved in nuclear domains (ND) 10 homing and reorganization
2003
Abstract We have recently shown that the minor capsid protein L2 of human papillomavirus type 33 (HPV33) recruits the transcriptional repressor Daxx into nuclear domains (ND) 10 and causes the loss of the transcriptional activator Sp100 from these subnuclear structures (Florin et al., 2002b) . In order to dissect L2 domains involved in nuclear translocation, ND10 homing, loss of Sp100, and recruitment of Daxx, a detailed deletion mutagenesis of L2 was performed. Using immunofluorescence and green fluorescent protein fusions, we have identified two nuclear localization signals (NLS) in the central and C-terminal part of L2, respectively, homologous to previously identified NLS in HPV6B L2 (S…
Update of the search for supersymmetric particles in scenarios with Gravitino LSP and Sleptons NLSP
2001
An update of the search for sleptons, neutralinos and charginos in the context of scenarios where the lightest supersymmetric particle is the gravitino and the next-to-lightest supersymmetric particle is a slepton, is presented, together with the update of the search for heavy stable charged particles in light gravitino scenarios and Minimal Supersymmetric Standard Models. Data collected in 1999 with the DELPHI detector at centre-of-mass energies around 192, 196, 200 and 202 GeV were analysed. No evidence for the production of these supersymmetric particles was found. Hence, new mass limits were derived at 95% confidence level.
Deformations of the seventh order Peregrine breather solutions of the NLS equation with twelve parameters.
2013
We study the solutions of the one dimensional focusing NLS equation. Here we construct new deformations of the Peregrine breather of order 7 with 12 real parameters. We obtain new families of quasi-rational solutions of the NLS equation. With this method, we construct new patterns of different types of rogue waves. We recover triangular configurations as well as rings isolated. As already seen in the previous studies, one sees appearing for certain values of the parameters, new configurations of concentric rings.
Deformations of third order Peregrine breather solutions of the NLS equation with four parameters
2013
In this paper, we give new solutions of the focusing NLS equation as a quotient of two determinants. This formulation gives in the case of the order 3, new deformations of the Peregrine breather with four parameters. This gives a very efficient procedure to construct families of quasi-rational solutions of the NLS equation and to describe the apparition of multi rogue waves. With this method, we construct the analytical expressions of deformations of the Peregrine breather of order N=3 depending on $4$ real parameters and plot different types of rogue waves.
Six-parameters deformations of fourth order Peregrine breather solutions of the NLS equation.
2013
We construct solutions of the focusing NLS equation as a quotient of two determinants. This formulation gives in the case of the order 4, new deformations of the Peregrine breather with 6 real parameters. We construct families of quasi-rational solutions of the NLS equation and describe the apparition of multi rogue waves. With this method, we construct the analytical expressions of deformations of the Peregrine breather of order 4 with 6 real parameters and plot different types of rogue waves.
Eighth order Peregrine breather solution of the NLS equation and their deformations with fourteen parameters.
2014
We construct new families of quasi-rational solutions of the NLS equation of order 8 with 14 real parameters. We obtain new patterns of different types of rogue waves. We recover the triangular configurations as well as rings isolated as found for the lower orders. Moreover, one sees appearing for certain values of the parameters, new configurations of concentric rings.
Higher order Peregrine breathers solutions to the NLS equation
2015
The solutions to the one dimensional focusing nonlinear Schrödinger equation (NLS) can be written as a product of an exponential depending on t by a quotient of two polynomials of degree N (N + 1) in x and t. These solutions depend on 2N − 2 parameters : when all these parameters are equal to 0, we obtain the famous Peregrine breathers which we call PN breathers. Between all quasi-rational solutions of the rank N fixed by the condition that its absolute value tends to 1 at infinity and its highest maximum is located at the point (x = 0, t = 0), the PN breather is distinguished by the fact that PN (0, 0) = 2N + 1. We construct Peregrine breathers of the rank N explicitly for N ≤ 11. We give …