Search results for "NPR."
showing 10 items of 144 documents
Fatal cerebellar haemorrhage due to phenprocoumon poisoning.
1996
A 32-year-old patient died of a cerebellar haemorrhage and the blood coagulation analysis before death suggested defective synthesis of vitamin K-dependent clotting factors due to vitamin K deficiency. The post-mortem toxicological examination of different tissues revealed phenprocoumon poisoning as the cause of death. The differential diagnosis of vitamin K deficiency and the toxicology of hydroxycoumarins are discussed.
Age-dependent differences in the effect of phenprocoumon on the vitamin K1-epoxide cycle in rats
1980
Abstract The anticoagulant activity and the pharmacokinetics of phenprocoumon as well as the effect of phenprocoumon on the vitamin K1-epoxide cycle in younger (12 weeks) and older (36 weeks) male inbred Lewis rats has been examined in a study of the mechanism responsible for the increase in the responsiveness to oral anticoagulant drugs (OAD's) with increasing age. After a single i.v.-dose of phenprocoumon (0†355 mg kg−1 the anticoagulant effect obtained was greater in older than in younger rats. There were no differences between younger and older rats in the rate of elimination, volume of distribution and in the free fraction and free concentration values of phenprocoumon in plasma and li…
Microbial Biofilms Along a Geochemical Gradient at the Shallow-Water Hydrothermal System of Vulcano Island, Mediterranean Sea
2022
Shallow water hydrothermal vents represent highly dynamic environments where strong geochemical gradients can shape microbial communities. Recently, these systems are being widely used for investigating the effects of ocean acidification on biota as vent emissions can release high CO2 concentrations causing local pH reduction. However, other gas species, as well as trace elements and metals, are often released in association with CO2 and can potentially act as confounding factors. In this study, we evaluated the composition, diversity and inferred functional profiles of microbial biofilms in Levante Bay (Vulcano Island, Italy, Mediterranean Sea), a well-studied shallow-water hydrothermal ve…
Dažas 16. gs. Rīgas raganu un burvju prāvas ar latviešu fragmentiem [...Rīgas raganu un burvju prāvas ...]
1938
Rakstu krājuma "Tautas vēsturei" atsevišķs novilkums no 167.-197. lpp.
La cultura ci salverà? Processi di touristification a base culturale nel centro storico di Palermo
2023
Negli ultimi tre decenni la cultura ha avuto un ruolo chiave nella costruzione delle politiche urbane, divenendo uno strumento decisivo nella definizione delle strategie di sviluppo economico e nell’accesso alla competizione globale che caratterizzano l’attuale regime di neoliberismo urbano (Miles e Paddison 2005). Anche nel sud Europa la cosiddetta rigenerazione a base culturale ha rappresentato e continua ancora oggi a rappresentare una vera e propria ortodossia urbana, che trova nel turismo tanto una ragione di esistenza quanto un campo di attuazione. In particolare, negli ultimi anni i centri storici di molte città sudeuropee sono stati oggetto di trasformazioni profonde in cui pratiche…
Tērvetes upes ielejas morfoloģija un veidošanās
2015
Bakalaura darbā apskatīta Tērvetes upes mūsdienu ieleja un procesi, kas to veidojuši laika posmā no Latvijas apledojuma Linkuvas oscilācijas līdz mūsdienām. Teorētiskajā daļā apskatīti galveni noteces ieleju veidotājspēki, kā arī morfoloģiskie procesi, kas veido mūsdienu Latvijas upju ielejām raksturīgos elementus. Sniegts ieskats bakalaura tapšanas gaitā izmantotajās pētniecības metodēs un materiālos. Rezultātu sadaļā analizēti izveidotie ielejas šķērsprofili un garenprofili, kā arī iegūtie Tērvetes un tās ielejas morfoloģiskie rādītāji.
Atmospheric radiative effects of an in-situ measured Saharan dust plume and the role of large particles
2007
This work will present aerosol size distributions measured in a Saharan dust plume between 0.9 and 12 km altitude during the ACE-2 campaign 1997. The distributions contain a significant fraction of large particles of diameters from 4 to 30 μm. Radiative transfer calculations have been performed using these data as input. Shortwave, longwave as well as total atmospheric radiative effects (AREs) of the dust plume are investigated over ocean and desert within the scope of sensitivity studies considering varied input parameters like solar zenith angle, scaled total dust optical depth, tropospheric standard aerosol profiles and particle complex refractive index. The results indicate that the lar…
Suicidālas uzvedības riska līmenis un antisuicidālie motīvi notiesātajiem vīriešiem, saistība ar apreibinošu vielu ļaunprātigu lietošanu
2017
Maģistra darba tēma ir «Suicidālas uzvedības riska līmenis un antisuicidālie motīvi notiesātajiem vīriešiem, saistībā ar apreibinošo vielu ļaunprātīgo lietošanu». Dotajā pētījuma mērķis ir izpētīt suicidālas uzvedības riska līmeni, antisuicidālas uzvedības motīvus un ļaunprātīgo apreibinošo vielu lietošanu notiesātiem vīriešiem. Pamatjēdzieni: suicidāla uzvedība, antisuicidāliem motīvi, apreibinošo vielu ļaunprātīga lietošana. Esošajā pētījuma tika izvirzīti 3 pētījuma jautājumi: Vai pastāv saistības starp suicidālas uzvedības riska līmenim un antisuicidāliem motīviem? Vai pastāv saistības starp suicidālas uzvedības riska līmenim un ļaunprātīgo apreibinošo vielu lietošanu? Vai pastāv saistī…
Post-operative computed tomography imaging evaluation of ascending aorta surgery
2021
Ascending thoracic aorta disease is often a life-threatening condition. Aortic aneurysm and aortic dissection are the most frequent ascending aorta diseases requiring surgical intervention. Surgical repair techniques of the ascending aorta are various; they include reconstruction of the ascending aorta by using a graft with or without a prosthetic valve, reconstruction with a composite artificial graft or using a biological graft, and reconstruction of the ascending aorta with a composite graft preserving the native valve and arch repair. The radiologist plays a key role in the identification of post-operative complications; differentiation from normal postoperative findings is fundamental.…
IT Service CMM soveltaminen pienen ja keskisuuren yrityksen IT-prosessien kehittämisessä
2009
Laakkonen, Ville Oskari Tietojärjestelmätieteen kandidaatin tutkielma Jyväskylä: Jyväskylän yliopisto, 2009. Pienissä ja keskisuurissa yrityksissä suunnittelemattomasti kehittyneet toimintamallit eivät usein enää riitä yrityksen koon kasvaessa. Tässä tutkielmassa selvitettiin kirjallisuuden perusteella kuinka IT Service Capability Maturity model soveltuu PK-yrityksen IT-prosessien kehittämiseen. Tällä hetkellä ei ole olemassa selkeää vastausta siihen, missä kasvuvaiheessa yrityksen kannattaa aloittaa prosessin kehittäminen. IT-prosessien kehittäminen vaatii yritykseltä erityisesti pitkäjänteisyyttä ja sitoutumista ennalta määritettyihin tavoitteisiin. Tutkielmassa havaittiin, että pienet j…