Search results for "NRA"
showing 10 items of 321 documents
Isomer and decay studies for the rp process at IGISOL
2012
This article reviews the decay studies of neutron-deficient nuclei within the mass region \ensuremathA=56--100 performed at the Ion-Guide Isotope Separator On-Line (IGISOL) facility in the University of Jyväskylä over last 25 years. Development from He-jet measurements to on-line mass spectrometry, and eventually to atomic mass measurements and post-trap spectroscopy at IGISOL, has yielded studies of around 100 neutron-deficient nuclei over the years. The studies form a solid foundation to astrophysical rp -process path modelling. The focus is on isomers studied either via spectroscopy or via Penning-trap mass measurements. The review is complemented with recent results on the ground and is…
JYFLTRAP: a Penning trap for precision mass spectroscopy and isobaric purification
2012
In this article a comprehensive description and performance of the double Penning-trap setup JYFLTRAP will be detailed. The setup is designed for atomic mass measurements of both radioactive and stable ions and additionally serves as a very high-resolution mass separator. The setup is coupled to the IGISOL facility at the accelerator laboratory of the University of Jyväskylä. The trap has been online since 2003 and it was shut down in the summer of 2010 for relocation to the upgraded IGISOL facility. Numerous atomic mass and decay energy measurements have been performed using the time-of-flight ion-cyclotron resonance technique. The trap has also been used in several decay spectroscopy expe…
5 – 7 gadus vecu bērnu jaunrades veicināšana tehnoloģiju mācību jomā pirmsskolā
2020
Kvalifikācijas darbs izstrādāts par tēmu “5 – 7 gadus vecu bērnu jaunrades veicināšana tehnoloģiju mācību jomā pirmsskolā”. Kvalifikācijas darba mērķis ir teorētiski noskaidrot un praktiski pārbaudīt, kā tehnoloģiju mācību jomas nodarbībās pirmsskolā veicināma 5 – 7 gadus vecu bērnu jaunrade. Pētījuma teorētiskajā daļā tika analizēta literatūra par tēmām jaunrade un tās veicināšana, 5 – 7 gadus vecu bērnu raksturojums un tehnoloģiju mācību jomas mācību saturs un pedagoģiskā darbības principi pirmsskolā. Pētījuma empīriskajā daļā tika veikta pedagoģiskā novērošana, lai izveidotu bērnu īsu raksturojumu un tiktu izvērtēts bērnu jaunrades līmenis pēc trīs izvirzītajiem kritērijiem un to rādītāj…
Joseph Conrad-Korzeniowski, an English Writer with a Polish Soul: Joseph Conrad’s Polish Heritage
2018
The article presents a portrait of Joseph Conrad-Korzeniowski, an English writer with a Polish soul. Conrad—the last Polish Romantic—did not only manage to introduce Polish dreams and longings into English (and Western) literature, but also transformed the Polish experience into a universal one. Writing about exotic, faraway places, he disseminated myths concerning Polish national identity, chivalric tradition and the Polish Eastern Borderland atmosphere and ethos. Conrad, a very demanding writer, never presents ready-made answers, nor does he offer simple solutions to the problems of his protagonists. Moreover, everybody can understand Conrad in their own personal way, for he is perceived …
Ongelmanratkaisun opettaminen todennäköisyystehtävissä
2017
Mitä enemmän oppilas tai opiskelija oivaltaa itse, sitä enemmän hän oppii ja nauttii ongelmanratkaisusta. Tämä ajatus toimii lähtökohtana tutkielmassa. Käsiteltävät tehtävät ovat tasoltaan yläkouluun ja / tai lukioon soveltuvia. Tutkielma antaa opettajalle käytännönläheisiä esimerkkejä opetustilanteessa hyödynnettävistä todennäköisyysongelmista. Tehtävistä esitetään useita ratkaisuvaihtoehtoja, jotta opettajan on helpompi samaistua erilaisiin ajattelutapoihin. Mikä tärkeintä, tutkielmaan on kehitetty kysymyksiä, joilla oppijaa voi ohjata hienovaraisesti eteenpäin ratkaisussaan. Tavoitteena on, että ratkoja keksii kysymysten avulla itse ratkaisun kuhunkin ongelmaan. Ongelmanratkaisutaitojen …
Polityczne i kryminalne tło zbrodni w Potępie (1932 r.)
2017
Opis zbrodni na Konradzie Piecuchu, polskim robotniku z Potępy na Górnym Śląsku,pojawia się we wszystkich opracowaniach poświęconych początkom Trzeciej Rzeszy. Autorzy literatury przedmiotu wskazują na mord, popełniony w nocy z 9 na 10 sierpnia 1932 r., jako przykład bezwzględnych metod walki politycznej hitlerowskich bojówek. Jednostronna interpretacja wypadków w Potępie, omawiana jest w powojennych opracowaniach historycznych polskich autorów, którzy zapewne z pobudek ideologicznych, nie dostrzegali kryminalnych motywów zbrodni. Tekst niniejszy pokazuje głośne zabójstwo z obu perspektyw. Nawiązuje w ten sposób do artykułu Richarda Bessela z 1977 r., który jako jedyny badacz próbował wskaz…
Omalizumab as alternative to chronic use of oral corticosteroids in severe asthma.
2019
Systemic/oral corticosteroids (OCS) have been used for decades in the management of acute asthma exacerbations and chronically in patients with uncontrolled severe asthma. However, while OCS are effective at treating acute exacerbations, there is only empirical evidence regarding the efficacy of OCS at reducing the rate of exacerbations. Evidence, although scarce, is suggestive of high exacerbation rates in severe asthma patients even when receiving maintenance treatment with OCS. In addition, use of OCS is associated with undesirable effects. Despite all this, physicians have continued to use OCS for managing severe asthma and acute exacerbation due to the lack of availability of effective…
Onset of effect and impact on health-related quality of life, exacerbation rate, lung function, and nasal polyposis symptoms for patients with severe…
2021
Background: ANDHI was done to assess the efficacy of benralizumab, including onset of effect and impact on health-related quality of life (HRQOL), exacerbation rate, lung function, and nasal polyposis symptoms. Methods: This phase 3b, randomised, double-blind, parallel-group, placebo-controlled ANDHI study was completed in adults (aged 18–75 years) with severe eosinophilic asthma with at least 2 exacerbations in the previous year, despite high-dose inhaled corticosteroid plus additional controllers, screening blood eosinophil counts of at least 150 cells per μL, and an Asthma Control Questionnaire 6 (ACQ-6) score of 1·5 or more. Patients who met eligibility criteria were randomly assigned (…
Age does not affect the efficacy of anti-IL-5/IL-5R in severe asthmatics
2019
Background: Healthcare decisions made on the basis of insufficient evidence may potentially have ineffective or even harmful consequences. The proportion of older ages (over 65 years) in randomized controlled trials (RCTs) for severe asthma is not enough to establish whether anti-IL-5/IL-5R therapies are equally effective in the elderly as in younger subjects. Methods: In order to assess the relationship between age and the efficacy of anti-IL-5 monoclonal antibodies (mABs) with respect to the risk of exacerbations and changes in FEV1, a meta-regression analysis via random-effect method was carried out by plotting the effect estimates (outcome variables) resulting from the pairwise meta-ana…
Therapeutic effects of benralizumab assessed in patients with severe eosinophilic asthma: Real-life evaluation correlated with allergic and non-aller…
2021
Corrado Pelaia,1 Claudia Crimi,2 Alida Benfante,3 Maria Filomena Caiaffa,4 Cecilia Calabrese,5 Giovanna Elisiana Carpagnano,6 Domenico Ciotta Jnr,7 Maria D’Amato,8 Luigi Macchia,9 Santi Nolasco,2 Girolamo Pelaia,1 Simona Pellegrino,7 Nicola Scichilone,3 Giulia Scioscia,10 Giuseppe Spadaro,11 Giuseppe Valenti,12 Alessandro Vatrella,7 Nunzio Crimi2 1Department of Health Sciences, University “Magna Graecia” of Catanzaro, Catanzaro, Italy; 2Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy; 3Department of Biomedicine and Internal and Specialistic Medicine, University of Palermo, Palermo, Italy; 4Allergology and Clinical Immunol…