Search results for "NTIC"

showing 10 items of 6004 documents

CIAS detection of Fasciola hepatica/F. gigantica intermediate forms in bovines from Bangladesh

2015

Fascioliasis is an important food-borne parasitic zoonosis caused by two trematode species, Fasciola hepatica and Fasciola gigantica. The characterisation and differentiation of Fasciola populations is crucial to control the disease, given the different transmission, epidemiology and pathology characteristics of the two species. Lineal biometric features of adult liver flukes infecting livestock have been studied to characterise and discriminate fasciolids from Bangladesh. An accurate analysis was conducted to phenotypically discriminate between fasciolids from naturally infected bovines (cattle, buffaloes) throughout the country. Morphometric analyses were made with a computer image analys…

0301 basic medicineFascioliasisVeterinary medicineBiometryFasciola gigantica030231 tropical medicineCattle DiseasesCattle Diseases03 medical and health sciences0302 clinical medicineHepaticaparasitic diseasesmedicineAnimalsFasciola hepaticaBangladeshbiologyFasciolabusiness.industryZoonosis030108 mycology & parasitologybiology.organism_classificationmedicine.diseaseFasciolaMalalties parasitàriesParasitologyCattleParasitologyLivestockbusinessBestiar boví
researchProduct

Histone Deacetylase Inhibitors from Marine Invertebrates

2020

Simple Summary Histone deacetylases (HDACs) are enzymes that control gene expression and are involved in the onset of serious human pathologies, including cancer; hence, their inhibitors (HDACis) have received increased attention in recent years. It is known that marine invertebrates produce significant amounts of molecules showing active pharmacological properties and an extensive spectrum of biomedical applications. This review is focused on the description of the molecular, biochemical, and, where available, physiological aspects of marine invertebrate-derived compounds that possess HDACi properties, taking into consideration their possible utilization as treatment agents against differe…

0301 basic medicineGene isoformbiomedical applicationsmarine invertebratesSettore BIO/05 - ZoologiaComputational biologyReviewhistone deacetylase inhibitorsGeneral Biochemistry Genetics and Molecular BiologyChromatin remodelinganticancer compound03 medical and health sciencesCnidaria0302 clinical medicineNon-histone proteinmarine invertebrateGene expressionEpigeneticsSettore BIO/06 - Anatomia Comparata E Citologiahistone deacetylase inhibitorlcsh:QH301-705.5General Immunology and MicrobiologybiologyMarine invertebratesanticancer compoundsPorifera030104 developmental biologyHistonelcsh:Biology (General)030220 oncology & carcinogenesisbiology.proteinbiomedical applicationHistone deacetylaseGeneral Agricultural and Biological SciencesEchinodermataBiology
researchProduct

An improved genome assembly uncovers prolific tandem repeats in Atlantic cod

2016

AbstractBackground: The first Atlantic cod (Gadus morhua) genome assembly published in 2011 was one of the early genome assemblies exclusively based on high-throughput 454 pyrosequencing. Since then, rapid advances in sequencing technologies have led to a multitude of assemblies generated for complex genomes, although many of these are of a fragmented nature with a significant fraction of bases in gaps. The development of long-read sequencing and improved software now enable the generation of more contiguous genome assemblies.Results: By combining data from Illumina, 454 and the longer PacBio sequencing technologies, as well as integrating the results of multiple assembly programs, we have …

0301 basic medicineHeterozygoteAssembly algorithmsSequence assemblyGenomicsRepetitive DNABiologyGenome03 medical and health sciences0302 clinical medicineAssembly consolidationTandem repeatIndel polymorphismGeneticsAnimalsGadusLong-read sequencing technologyPromoter Regions GeneticMicrosatellitesRepeated sequenceGenePacBioGeneticsHeterozygosityDinucleotide repeatsMolecular Sequence AnnotationGenomicsSequence Analysis DNAbiology.organism_classification030104 developmental biologyGadus morhuaTandem Repeat SequencesEvolutionary biologyPyrosequencingAtlantic cod030217 neurology & neurosurgeryResearch ArticleBiotechnology
researchProduct

In vitro comparison of passive and continuous ultrasonic irrigation in curved root canals

2016

BACKGROUND The efficacy of endodontic irrigation procedures can be compromised by the complexity of the root canal system. Delivering irrigants to the apical third of curved canals presents a particular challenge to endodontists. This study compared the effects of two ultrasonic irrigation techniques on the penetration of sodium hypochlorite into the main canal and simulated lateral canals of curved roots in extracted teeth. MATERIAL AND METHODS Two sets of simulated lateral canals were created at 2, 4, and 6 mm from the working length in 60 single-rooted teeth (6 canals/tooth, n = 360 canals). The teeth were randomly divided into three experimental irrigation groups: group 1 (n = 20), posi…

0301 basic medicineIrrigationEndodontic irrigationRoot canalDentistryOdontologíaContinuous ultrasonic irrigationOperative Dentistry and EndodonticsPassive ultrasonic irrigation03 medical and health scienceschemistry.chemical_compound0302 clinical medicinemedicineotorhinolaryngologic diseasesGeneral DentistryMathematicsCurved root canalRoot canal irrigationUltrasonic irrigationbusiness.industryResearch030206 dentistryPenetration (firestop)Ciencias de la salud030104 developmental biologymedicine.anatomical_structureSodium hypochlorite solutionPositive pressure irrigationchemistrySodium hypochloriteDentistry (all)UNESCO::CIENCIAS MÃ DICASsense organs:CIENCIAS MÃ DICAS [UNESCO]business
researchProduct

Update of the therapeutic planning of irrigation and intracanal medication in root canal treatment. A literature review

2019

Background The success of endodontic treatment derives from the complete elimination of microorganisms capable of causing an intraradicular or extraradicular infection. To achieve a more effective eradication of these microorganisms, endodontic instrumentation must always be implemented with abundant irrigation, which has to achieve chemical, mechanical and biological effects. The irrigators most used today are NaOCl, CHX and EDTA, released into the ducts through different techniques such as syringe, manual agitation, positive or negative apical pressure, sonic or ultrasonic activation, PIPS and PDT. The objective of this review is to update the different irrigating solutions and intracanal…

0301 basic medicineIrrigationRoot canalDentistryOdontologíaReviewAntibacterial effectOperative Dentistry and Endodontics03 medical and health sciences0302 clinical medicineEnterococcus faecalismedicineEndodonciaGeneral DentistryEndodontic retreatmentInfeccionesbusiness.industryAntimicrobial efficacy030206 dentistry:CIENCIAS MÉDICAS [UNESCO]030104 developmental biologymedicine.anatomical_structureUNESCO::CIENCIAS MÉDICASIRRIGATING SOLUTIONSbusinessSystematic searchJournal of Clinical and Experimental Dentistry
researchProduct

Intestinal helminth fauna of the shortfin mako Isurus oxyrinchus (Elasmobranchii: Lamnidae) in the northeast Atlantic Ocean.

2017

Large oceanic sharks represent a suitable model to investigate the influence of a host's oceanic conditions on the structure of its helminth communities. In this study, we describe the intestinal helminth fauna, and investigate determinants of infracommunity structure, in 39 specimens of shortfin mako Isurus oxyrinchus collected in the NE Atlantic. Six cestode species were found in the spiral valve of makos: 3 are typical from lamnid sharks, namely, gravid specimens of Clistobothrium montaukensis, Gymnorhynchus isuri and Ceratobothrium xanthocephalum, and 3 are immature specimens of cestode species common to several elasmobranchs, namely, Dinobothrium septaria, Nybelinia lingualis, and Phyl…

0301 basic medicineIsurusbiologyEcologyFaunafungiPelagic zone030108 mycology & parasitologyAquatic Sciencebiology.organism_classification03 medical and health sciencesElasmobranchiiSpiral valveHelminthsLamnidaeSharksAnimalsSpecies richnessHelminthiasis AnimalAtlantic OceanEcology Evolution Behavior and SystematicsTrophic levelDiseases of aquatic organisms
researchProduct

Chronic nail biting, orthodontic treatment and Enterobacteriaceae in the oral cavity

2019

Background Chronic nail biting is common in children and young adults. Auto inoculation of environmental pathogens can manifest as infection in distant organs. Multi-drug resistance gram negative bacteria are on the rise globally. Several of the foodborne bacteria fall within the Enterobacteriaceae family but very few studies have explored these microbes in the oral cavity of children with chronic nail-biting habit or orthodontic treatment. The study aims to investigate oral load of Enterobacteriaceae in children with chronic nail-biting habit and or those undergoing orthodontic treatment. Material and methods 150 children (no nail-biting n=30, nail biting n=60, fixed orthodontic treatment …

0301 basic medicineKlebsiellaDentistryOrthodonticsDrug resistanceOral cavity03 medical and health sciences0302 clinical medicineparasitic diseasesMedicineConcentrated OralGeneral DentistryNail bitingFoodborne bacteriabiologybusiness.industryResearchIncidence (epidemiology)030206 dentistry:CIENCIAS MÉDICAS [UNESCO]medicine.diseasebiology.organism_classificationEnterobacteriaceae030104 developmental biologyUNESCO::CIENCIAS MÉDICASbusiness
researchProduct

Entrapment of Citrus limon var. pompia Essential Oil or Pure Citral in Liposomes Tailored as Mouthwash for the Treatment of Oral Cavity Diseases

2020

This work aimed at developing a mouthwash based on liposomes loading Citrus limon var. pompia essential oil or citral to treat oropharyngeal diseases. Vesicles were prepared by dispersing phosphatidylcholine and pompia essential oil or citral at increasing amounts (12, 25 and 50 mg/mL) in water. Transparent vesicle dispersions were obtained by direct sonication avoiding the use of organic solvents. Cryogenic transmission electron microscopy (cryo-TEM) confirmed the formation of unilamellar, spherical and regularly shaped vesicles. Essential oil and citral loaded liposomes were small in size (~110 and ~100 nm, respectively) and negatively charged. Liposomes, especially those loading citral, …

0301 basic medicineLemonsSonicationkeratinocyte migrationlcsh:Medicinelcsh:RS1-441Pharmaceutical Sciencehydrogen peroxide02 engineering and technologyMalalties de la bocaCitral<i>Streptococcus mutans</i>law.inventionlcsh:Pharmacy and materia medica03 medical and health scienceschemistry.chemical_compoundlawPhosphatidylcholinescratch assayDrug DiscoveryLlimonesanticaries activityKeratinocyte migration<i>Citrus limon</i> essential oilHydrogen peroxideEssential oilLiposomeOlis essencialsChromatographyVesiclelcsh:RStreptococcusEstreptococs021001 nanoscience & nanotechnology030104 developmental biologyMouth diseaseschemistryEssences and essential oilsMolecular Medicine0210 nano-technology
researchProduct

Apnea events in neonatal age: A case report and literature review.

2019

Abstract Background Among the most common autonomic signs visible in preterm neonates, apnea can represent the first sign of several neurologic and non-neurologic disorders, and seizure is a relatively infrequent cause. Herein authors present a case of neonatal autonomic apnea, discussing the polygraphic video-EEG features of this pathological entity and the differential diagnosis with central apnea and autonomic apnea. Case report A female preterm Caucasian infant (29 + 4 weeks' gestational age (GA)), first twin of a twin pregnancy, at birth was intubated and surfactant administration was performed. She was ventilated via invasive ventilation for three days, with subsequent weaning with no…

0301 basic medicineLevetiracetamCentral apneaVideo RecordingDiseasesInfant Premature Diseases0302 clinical medicinenewbornDiagnosisHypoxiaApneaSleep apneaGestational ageElectroencephalographyGeneral MedicineSleep Apnea CentralAnesthesiaNervous System Diseases; Bradycardia; Cyanosis; Diagnosis Differential; Humans; Hypoxia; Infant Newborn; Infant Premature; Infant Premature Diseases; ; Sleep ApneaBreathingAnticonvulsantsFemalemedicine.symptomInfant PrematureBradycardiaSleep ApneaContext (language use)Gestational AgeNODiagnosis Differential03 medical and health sciencesSeizuresHeart ratemedicineBradycardiaDiseases in TwinsHumansPrematureCyanosisbusiness.industryInfant NewbornInfantapneamedicine.disease030104 developmental biologyAutonomic Nervous System DiseasesDifferentialNervous System Diseasesbusinesspreterm030217 neurology & neurosurgeryneurologic disorders
researchProduct

Anti-Cancer Activity of Resveratrol and Derivatives Produced by Grapevine Cell Suspensions in a 14 L Stirred Bioreactor

2017

International audience; In the present study, resveratrol and various oligomeric derivatives were obtained from a 14 L bioreactor culture of elicited grapevine cell suspensions (Vitis labrusca L.). The crude ethyl acetate stilbene extract obtained from the culture medium was fractionated by centrifugal partition chromatography (CPC) using a gradient elution method and the major stilbenes contained in the fractions were subsequently identified by using a (13)C-NMR-based dereplication procedure and further 2D NMR analyses including HSQC, HMBC, and COSY. Beside δ-viniferin (2), leachianol F (4) and G (4'), four stilbenes (resveratrol (1), ε-viniferin (5), pallidol (3) and a newly characterized…

0301 basic medicineMagnetic Resonance SpectroscopyDimerEthyl acetatePharmaceutical ScienceresveratrolResveratrolAnalytical Chemistrybioreactorchemistry.chemical_compoundBioreactors0302 clinical medicineStilbenesDrug DiscoveryVitisphytostilbenesMolecular Structure[CHIM.ORGA]Chemical Sciences/Organic chemistryBiological activity3. Good healthanticancer activityBiochemistryBatch Cell Culture TechniquesChemistry (miscellaneous)030220 oncology & carcinogenesisMolecular MedicineVitis labruscaCell SurvivalArticlePallidollcsh:QD241-44103 medical and health scienceslcsh:Organic chemistry[ CHIM.ORGA ] Chemical Sciences/Organic chemistryCell Line TumorPlant Cellsfibroblasts[SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular BiologymelanomaHumans[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyPhysical and Theoretical ChemistryCell growthresveratrol; phytostilbenes; melanoma; fibroblasts; anticancer activity; bioreactor; Vitis labruscaOrganic Chemistry[CHIM.ORGA] Chemical Sciences/Organic chemistryAntineoplastic Agents Phytogenic030104 developmental biologychemistryCell cultureFetal bovine serumChromatography LiquidMolecules
researchProduct