Search results for "Nabis"

FIRST EPISODE PSYCHOSIS PATIENTS WHO USED CANNABIS DEVELOP THEIR ILLNESS AT A SIGNIFICANTLY YOUNGER AGE THAN THOSE WHO NEVER USED CONSISTENTLY ACROSS…

2018

Background: Patients presenting to psychiatric services with their first episode of psychosis (FEP) report higher rates of previous cannabis use than the general population (Donoghue et al., 2011; Myles, Myles and Large, 2016). Evidence suggested that patients suffering from psychosis with a history of cannabis use have an earlier age of onset of psychosis (AOP) than those who never used it (Di Forti et al., 2013). We aim to investigate if the reported association between use of cannabis and AOP is consistent across different countries, once having taken into account different patterns of cannabis use (i.e. frequency of use and age at first use). Methods: We analysed data on patterns of lif…

Cannabis consumption and the risk of psychosis

2017

Summary Objectives: Cannabis is the most widely used illicit drug globally and its use has been linked to an increased risk for psychotic disorders. An association between cannabis consumption and psychotic symptoms was consistently reported by several studies. This case-control study aimed to widen the current findings about the impact of cannabis exposure on the risk of psychosis, by investigating the pattern of cannabis consumption in a sample of first-episode of psychosis (FEP) patients compared to healthy controls. Material and methods: 68 individuals who presented for the first time to mental health services of Palermo (Italy) with an ICD-10 diagnosis of psychotic disorders and 74 hea…

FIRST EPISODE PSYCHOSIS PATIENTS ACROSS EUROPE DIFFER IN INTELLECTUAL QUOTIENT (IQ) AND EXPOSURE TO ENVIRONMENTAL HAZARDS

2018

Background Children who later develop Schizophrenia on average are more likely to present with lower IQ; this has been considered evidence for the neurodevelopmental theory of schizophrenia. Though, recent studies have shown that first episode psychosis patients with a history of cannabis use have significantly higher premorbid and current IQ compared to those who never used it. This suggests that abnormal early neurodevelopment does not explain the aetiology of all cases of Schizophrenia, leaving space to environmental hazards. The present study aims to: investigate differences in IQ, as a marker of neurodevelopment, and in exposure to environmental risk factors in a large sample first epi…

DUP AND CANNABIS CONSUMPTION IN A SICILIAN FIRST EPISODE PSYCHOTIC (FEP) SAMPLE

2011

Cannabis Use and Social Anxiety in Adolescence: The Role of Facilitation Expectancies

2015

Cannabis use is frequently related to social anxiety in young adulthood, but the nature of this relationship is unclear. Moreover, much research has been conducted on the role of cannabis effects expectancies and their relationship to social anxiety among young adults, but less is known about adolescence. The study examined the relationship between social anxiety, cannabis use patterns, and cannabis effects expectancies among a nonclinical sample of 1,305 adolescents (51% female). Non-users reported higher social anxiety scores than non-problematic and risky users. Compared to users, non-users had more negative expectancies. Risky and problematic users showed higher social and sexual facili…

Hábitos de consumo de drogas y percepción sobre los efectos en salud y rendimiento académico en estudiantes de Psicología en la Universidad de Huelva

2014

El objetivo del trabajo es describir las prevalencias y las relaciones entre las diferentes drogas en estudiantes universitarios. Además conocer la percepción que tienen los estudiantes sobre los efectos de las drogas en el rendimiento académico y en la salud. La muestra está compuesta por 153 estudiantes de psicología de la Universidad de Huelva. Los datos de consumo y percepción se recogen mediante un cuestionario, anónimo y voluntario. Nuestros resultados ponen de manifi esto que las sustancias más consumidas y de inicio más temprano son el alcohol, el tabaco y el cannabis, por tanto, se confi rman las tendencias encontradas en jóvenes. Del mismo modo, se confi rma el patrón de policonsu…

Detectability of cannabinoids in the serum samples of cannabis users: Indicators of recent cannabis use? A follow‐up study

2021

Forensic toxicologists are frequently required to predict the time of last cannabis consumption. Several studies suggested the utility of minor cannabinoids as indicators of recent cannabis use. Because several factors influence blood cannabinoid concentrations, the interpretation of serum cannabinoid concentrations remains challenging. To assess the informative value of serum cannabinoid levels in cannabis users (in total N = 117 patients, including 56 patients who stated an exact time of last cannabis use within 24 h before blood sampling), the detectability of cannabinoids, namely delta-9-tetrahydrocannabinol (delta-9-THC), 11-hydroxy-delta-9-THC, 11-nor-9-carboxy-delta-9-THC, cannabichr…

Comparing illicit drug use in 19 European cities through sewage analysis

2012

Abstract: The analysis of sewage for urinary biomarkers of illicit drugs is a promising and complementary approach for estimating the use of these substances in the general population. For the first time, this approach was simultaneously applied in 19 European cities, making it possible to directly compare illicit drug loads in Europe over a 1-week period. An inter-laboratory comparison study was performed to evaluate the analytical performance of the participating laboratories. Raw 24-hour composite sewage samples were collected from 19 European cities during a single week in March 2011 and analyzed for the urinary biomarkers of cocaine, amphetamine, ecstasy, methamphetamine and cannabis u…

Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations

2014

European Community Recent years have seen considerable progress in epidemiological and molecular genetic research into environmental and genetic factors in schizophrenia, but methodological uncertainties remain with regard to validating environmental exposures, and the population risk conferred by individual molecular genetic variants is small. There are now also a limited number of studies that have investigated molecular genetic candidate gene-environment interactions (G x E), however, so far, thorough replication of findings is rare and G x E research still faces several conceptual and methodological challenges. in this article, we aim to review these recent developments and illustrate h…

effect of the extraction of proteins from hemp press-cakes on their functionalities

2019

Plant proteins are a coherent option to feed the planet while limiting global warming. Common proteins (wheat, soya and maize) will soon no longer be sufficient to meet the increased demand for proteins. This thesis focuses on the development of a new source of plant protein for human consumption, based on a co-product of the oil mill: hemp proteins from press-cake. To meet this objective, the three main lines of action are: the definition of extraction conditions, the study of the physico-chemical properties of the isolates extracted under the defined conditions and the study of their emulsifying properties. The data in the literature on the extraction of hemp proteins are limited and not …