Search results for "Nail"
showing 10 items of 216 documents
Temporal speciation pattern in the western Mediterranean genus Tudorella P. Fischer, 1885 (Gastropoda, Pomatiidae) supports the Tyrrhenian vicariance…
2009
The land snail genus Tudorella shows a peculiar disjunct distribution around the western Mediterranean coasts. Despite high phenotypic plasticity, only two species with a disputed number of subspecific taxa are currently recognised. We delimited the species with mitochondrial (COI & 16S) and nuclear (ITS-1) markers based on the unified species concept and suggested that there are eight species in the genus, two of them currently undescribed. Applying Bayesian phylogenetic model selection, we tested four different biogeographic hypotheses that could be causal for the current distribution pattern of extant Tudorella species. A scenario involving vicariance events resulting from the repeated s…
The complex interplay between Notch signaling and Snail1 transcription factor in the regulation of epithelial–mesenchymal transition (EMT)
2015
Background The epithelial–mesenchymal transition (EMT) is a highly coordinated process observed during embryonic development and adult tissue repair. It is characterized by the loss of cell–cell adhesion and apicobasal polarity, and the transition to a cell type with a spindle-like phenotype able to migrate through the basal membranes. Methods This review article includes available date from peer-reviewed publications associated with the role of Notch signaling and Snail1 transcription factor in activation and regulation of EMT. Results Growing evidences in the past few years demonstrated a significant role of Notch in EMT activation. It is not surprising because this pathway is the nexus o…
Low toenail chromium concentration and increased risk of nonfatal myocardial infarction
2005
Chromium intake may increase insulin sensitivity, glucose tolerance, and the ratio of high density lipoprotein cholesterol to low density lipoprotein cholesterol. However, the epidemiologic evidence on the association between chromium and cardiovascular disease is very limited. To determine whether low toenail chromium concentrations were associated with risk of nonfatal myocardial infarction, the authors conducted an incident, population-based, case-control study in eight European countries and Israel in 1991-1992. Cases (n = 684) were men with a first diagnosis of myocardial infarction recruited from the coronary units of participating hospitals. Controls (n = 724) were men selected rando…
Production and chronobiology of emergence of the cercariae of Euparyphium albuferensis (Trematoda: Echinostomatidae).
1999
The production and the chronobiology of emergence of the cercariae of Euparyphium albuferensis from Gyraulus chinensis experimentally infected with a single miracidium were established during 28 consecutive days from the first day of cercarial shedding. Moreover, the effect of a sudden change in light-dark cycling was investigated. Although the daily cercarial shedding rates show great variability, a progressive increase in cercarial production was observed in the first weeks of the cercarial shedding periods, probably in relation to the demography of intramollusean larval stages. Under 12:12 light-dark cycling condition;, it, albuferensis cercariae emerged in the light, and the rhythm was …
Positive selection in development and growth rate regulation genes involved in species divergence of the genus Radix
2015
AbstractBackgroundLife history traits like developmental time, age and size at maturity are directly related to fitness in all organisms and play a major role in adaptive evolution and speciation processes. Comparative genomic or transcriptomic approaches to identify positively selected genes involved in species divergence can help to generate hypotheses on the driving forces behind speciation. Here we use a bottom-up approach to investigate this hypothesis by comparative analysis of orthologous transcripts of four closely related EuropeanRadixspecies.ResultsSnails of the genusRadixoccupy species specific distribution ranges with distinct climatic niches, indicating a potential for natural …
Consequences of food-attraction conditioning in Helix: a behavioral and electrophysiological study
1996
Food-attraction conditioning is a learning phenomenon by which adult Helix pomatia acquire the ability to locate food through exposure to that particular food. Food-conditioned snails can be distinguished from ‘naive’ snails during their approach to food. ‘Naive’ snails keep their tentacles upright — whereas ‘food-conditioned’ animals bend the tentacles down-ward, in a horizontal orientation, pointed in the direction of the food.
Motores de búsqueda y derechos de autor: infracción y responsabilidad
2015
Los motores de búsqueda se configuran como herramientas indispensables para localizar fácilmente cualquier tipo de información entre las más de tres billones de páginas web existentes en la red. Estos buscadores se presentan, de facto, como instrumentos básicos para que todo usuario pueda tener acceso a la información, cultura y educación, de manera que están convirtiéndose en unas herramientas indispensables para el libre desarrollo de las personas. Sin embargo, a pesar de estas ventajas, en ocasiones, los buscadores vuelcan contenidos protegidos en la página de resultados sin autorización de su titular, de forma que de no mediar algún límite o excepción tasado en la ley, pueden estar vuln…
Innovative and Applied Research in Biology: Proceedings
2022
The collection contains SCIENTIFIC articles on the topics of the LU 80 conference reports. The main focus is on innovative and applied research in biology and interdisciplinary fields.
Therapeutic targeting of SNAIL, RKIP, and YY1 in tumor metastasis and drug resistance
2020
Abstract Cancer is the leading cause of deaths worldwide and is of great importance. Metastasis-inducing the majority of cancer related deaths is a principal problem in cancer treatment. Therefore, therapy regimes preventing metastasis formation are of prominent importance to improve the outcome of malignant diseases. The epithelial-mesenchymal transition (EMT) is a predominant process associated with the onset of metastasis and converts epithelial cells to mesenchymal cells. In this chapter, we concentrated on three proteins involved in the metastasis and EMT: RKIP, SNAIL, and YY1. Briefly, SNAIL and YY1 are overexpressed in many cancers, while RKIP is downregulated. Therefore, these prote…
Džan Ailin dzīves gājums un tā atspoguļojums viņas literārajos darbos
2019
Džan Ailin ir izcila ķīniešu rakstniece, kura dzīvoja 1920.-1995. gados. Dzimusi aristokrātiskā ģimenē, rakstniece bija radīta, lai dzīvotu labu dzīvi. Bet jau agrā jaunībā meitene saprata, ka viņas dzīve nebūs viegla. Tēvs bija opija atkarīgais un māte pameta savus bērnus, lai dotos uz Franciju, jo viņas vīrs bija apņēmis mīļāko. Jaunā meitene dzīves laikā piedzīvoja dažādas nelaimes un grūtības, bet viņa iemācījās no visām šīm likstām un ķibelēm. Džan Ailin sāka padziļināti studēt ķīniešu valodu un literatūru, kā arī angļu valodu un literatūru, kas palīdzēja izveidot rakstnieces unikālo stilu, kur viņa saglabāja Ķīnas tradicionālās literatūras elementus un pievienoja tiem rietumu stilu un…