Search results for "Native"

Search for potential Angiotensin Converting Enzyme (ACE)-inhibitors from plants

2001

MeOH extracts, fractions and pure substances from Musanga cecropioides, Cecropia species and Crataegus oxyacantha /C. monogyna were screened by using an in vitro bio-assay based on the inhibition of Angiotensin Converting Enzyme (ACE), as measured from the enzymatic cleavage of the chromophore-fluorophore-labelled substrate dansyltriglycine into dansylglycine and diglycine. Phenolic acids showed no significant ACE-inhibition whereas flavonoids and proanthocyanidins demonstrated inhibitory activity at 0.33 mg/ml using this test system.

Development of aDrosophila melanogasterspliceosensor system forin vivohigh-throughput screening in myotonic dystrophy type 1

2014

AbstractAlternative splicing of pre-mRNAs is an important mechanism that regulates cellular function in higher eukaryotes. A growing number of human genetic diseases involve splicing defects that are directly connected to their pathology. In myotonic dystrophy type 1 (DM1), several clinical manifestations have been proposed to be the consequence of tissue-specific missplicing of numerous genes. These events are triggered by an RNA gain-of-function and resultant deregulation of specific RNA-binding factors, such as the nuclear sequestration of muscleblind-like family factors (MBNL1-MBNL3). Thus, the identification of chemical modulators of splicing events could lead to the development of the…

Wordarrows: El poder representativo del lenguaje en la obra de no ficción de N. Scott Momaday

2012

This article focuses on two non-fiction works by Native American author N. Scott Momaday: his 1969 historical memoir The Way to Rainy Mountain and his essay collection The Man Made of Words. It specifically tackles performative conceptions of language in the Kiowa storytelling tradition, where words are experienced as speech acts that have the power to intervene in surrounding realities. Taking into account 20th century ethno-cultural and linguistic policies in the United States, the article also reflects on the role indigenous languages may play in contemporary Native American Literature, which has most often been written in English.

Baltic Journal of English Language, Literature and Culture, N. 4 

2014

Identity in Moon Palace by Paul Auster

2021

National audience

Staphylococcal Biofilms:Challenges in the Discovery of Novel Antiinfective Agents

2011

Staphylococci can induce a wide spectrum of infectious diseases that are associated with remarkable morbidity and mortality [1]. In fact, community and hospital-acquired methicillin resistant Staphylococcus aureus (MRSA) is a major health problem that has created a pressing need for novel therapeutic options [2]. Importantly, pathogenic staphylococci have not only an amazing ability to acquire resistance to antibiotics, but also to form biofilms, bacterial communities that grow on surfaces and are surrounded by a self-produced polymer matrix. This latter characteristic is likely the most important virulence factor of staphylococci in the development of the chronic form of infectious disease…

Weighted Evaluation Framework for Cross-Platform App Development Approaches

2016

Cross-platform app development is very challenging, although only two platforms with significant market share (iOS and Android) remain. While device fragmentation – multiple, only partly compatible versions of a platform – has been complicating matters already, the need to target different device classes is a new emergence. Smartphones and tablets are relatively similar but app-enabled devices such as TVs and even cars typically have differing capabilities. To facilitate usage of cross-platform app development approaches, we present work on an evaluation framework. Our framework provides a set of up-to-date evaluation criteria. Unlike prior work on this topic, it offers weighted assessment …

Medicinal Plants from Near East for Cancer Therapy.

2017

Background: Cancer is one of the major problems affecting public health worldwide. As other cultures, the populations of the Near East rely on medicinal herbs and their preparations to fight cancer. Methods: We compiled data derived from historical ethnopharmacological information as well as in vitro and in vivo results and clinical findings extracted from different literature databases including (PubMed, Scopus, Web of Science, and Google Scholar) during the past two decades. Results: In this survey, we analyzed the huge amount of data available on anticancer ethnopharmacological sources used in the Near East. Medicinal herbs are the most dominant ethnopharmacological formula used among ca…

Angļu valodas vārdu krājuma attīstīšanas veidi tehnikuma ēdināšanas pakalpojumu specialitātes audzēkņu apmācībā

2019

Dotā zinātniskā pētījuma temats ir izpētīt dažādus angļu valodas vārdu krājuma attīstīšanas veidus tehnikuma ēdināšanas pakalpojumu specialitātes audzēkņu apmācībā. Viena no problēmām apgūstot profesionālo vārdu krājumu ir, ka nav pietiekošu mācību materiālu, kas palīdzētu audzēkņiem uzlabot to un mūsdienu skolēniem vairs nepatīk tradicionālā mācīšanās no grāmatām, kā tas bija agrāk. Bez tam, neviens mācību līdzeklis nepievērš uzmanību skolēnu mācīšanās stiliem, kas ietekmē viņu mācīšanās rezultātus. Pamatojoties uz teorētiskās literatūras izpēti par angļu valodas mācīšanu īpašiem nolūkiem, vārdu krājuma attīstīšanu vispārīgajā un profesionālajā angļu valodā un dažādiem mācīšanās stiliem, t…

Dscam1 Is Required for Normal Dendrite Growth and Branching But Not for Dendritic Spacing in Drosophila Motoneurons

2014

Down syndrome cell adhesion molecule, Dscam, serves diverse neurodevelopmental functions, including axon guidance and synaptic adhesion, as well as self-recognition and self-avoidance, depending on the neuron type, brain region, or species under investigation. InDrosophila, the extensive molecular diversity that results from alternative splicing of Dscam1 into >38,000 isoforms provides neurons with a unique molecular code for self-recognition in the nervous system. Each neuron produces only a small subset of Dscam1 isoforms, and distinct Dscam1 isoforms mediate homophilic interactions, which in turn, result in repulsion and even spacing of self-processes, while allowing contact with neig…