Search results for "Nod"
showing 10 items of 4007 documents
Oral lichen planus, hepatitis C virus, and HIV: no association in a cohort study from an area of high hepatitis C virus endemicity
2004
Abstract Objectives We sought to assess the age-specific prevalence of oral lichen planus (OLP) in Mediterranean patients with chronic hepatitis C virus (HCV) and to evaluate the features of OLP in relation to sex, smoking, HCV genotype, HIV-1 coinfection, and antiviral treatments. Methods In all, 178 anti-HCV-positive adults (60 women and 118 men; age range 20-66 years) recruited from two cohorts (104 HIV-negative patients and 74 patients with HIV coinfection) underwent oral examination. Results Overall prevalence of OLP was 2.8% (5 of 178) (male/female ratio 0.2; odds ratio=0.119; 95% confidence interval=0.013-1.106), only among HIV-negative participants, always in the reticular pattern, …
Predictors of serious adverse events and non-response in cirrhotic patients with primary biliary cholangitis treated with obeticholic acid
2022
Background & Aims Obeticholic acid (OCA) has recently been restricted in patients with primary biliary cholangitis (PBC) with "advanced cirrhosis" because of its narrow therapeutic index. We aimed to better define the predicting factors of hepatic serious adverse events (SAEs) and non-response in cirrhotic patients undergoing OCA therapy. Methods Safety and efficacy of treatment were evaluated in a cohort of consecutive PBC cirrhotic patients started with OCA. OCA response was evaluated according to the Poise criteria. Risk factors for hepatic SAEs and non-response were reported as risk ratios (RR) with 95% confidence intervals (CIs). Results One hundred PBC cirrhotics were included, 97…
MRI versus 64-row MDCT for diagnosis of hepatocellularcarcinoma
2009
To compare the diagnostic capability of multidetector computed tomography (MDCT) and magnetic resonance imaging (MRI) for the detection of hepatocellular carcinoma (HCC) tumour nodules and their effect on patient management.A total of 28 patients (25 male, 3 female, mean age 67 +/- 10.8 years) with biopsy-proven HCC were investigated with 64-row MDCT (slice 3 mm native, arterial and portal-venous phase, 120 mL Iomeprol, 4 mL/s, delay by bolus trigger) and MRI (T1fs fl2d TE/TR 2.72/129 ms, T2tse TE/TR 102/4000 ms, 5-phase dynamic contrast-enhanced T1fs fl3d TE/TR 1.56/4.6, Gadolinium-DTPA, slice 4 mm). Consensus reading of both modalities was used as reference. Tumour nodules were analyzed w…
Hepatocellular Carcinoma Presenting at Contrast-Enhanced Multi–Detector-Row Computed Tomography or Gadolinium-Enhanced Magnetic Resonance Imaging as …
2012
OBJECTIVE: The objective of the study was to measure growth rate and to determine the optimal interval time for imaging follow-up of hepatocellular carcinomas (HCCs) presenting at multi-detector-row computed tomography (MDCT) or magnetic resonance imaging (MRI) as small, indeterminate lesions. METHODS: We included patients with cirrhosis with HCC initially presenting as indeterminate lesion of 2 cm or less at MDCT or MRI August 2005 to August 2009 and with available imaging follow-up. Measures of tumor growth included tumor volume doubling time (TVDT), tumor percentual diameter increase, and tumor percentual volume increase. RESULTS: We examined 48 patients (mean age, 64 years) with 69 HCCs…
Uncommon imaging evolutions of focal liver lesions in cirrhosis.
2019
Objective: The purpose of this article is to describe and illustrate uncommon imaging evolutions of benign (i.e., cyst, hemangioma, focal nodular hyperplasia-like nodules, and hepatic angiomyolipoma) and malignant (i.e., HCC and non HCC malignancies) lesions in a cirrhotic liver. The content highlights relevant pathogenesis and imaging clues for proper differential diagnosis. Revision of prior imaging and knowledge of these scenarios may help the abdominal radiologist to reach a noninvasive diagnosis and direct the patient to the most appropriate clinical management. Conclusion: Uncommon imaging evolutions of focal liver lesions in cirrhosis may represent a challenge for the abdominal radio…
Surveillance Program for Diagnosis of HCC in Liver Cirrhosis: Role of Ultrasound Echo Patterns
2017
International guidelines suggest ultrasound surveillance for hepatocellular carcinoma (HCC) early diagnosis in liver cirrhosis (LC) patients, but 40% of nodules <2 cm escape detection. We investigated the existence of an ultrasound pattern indicating a higher risk of developing HCC in patients under surveillance. 359 patients with LC (Child-Pugh A-B8) underwent ultrasound screening (median follow-up 54 months, range 12–90 months), liver function tests, alpha-fetoprotein assay, and portal hypertension evaluation. Echo patterns were homogeneous, bright liver, coarse, coarse small nodular pattern, and coarse large nodular pattern. During follow-up 13.9% developed HCC. At multivariate analys…
Liver stiffness measurement in patients with nodular regenerative hyperplasia undergoing magnetic resonance elastography
2020
Purpose Nodular regenerative hyperplasia (NRH) may mimic cirrhosis at imaging. We aim to investigate the effect of NRH on liver stiffness measurement (LSM) obtained with magnetic resonance elastography (MRE).Methods This retrospective, Institutional Review Board-approved study included 37 subjects with NRH (Group 1) and no or minimal fibrosis (F0-F1), a control group (Group 2) made of 30 subjects with non-advanced fibrosis (F0-F2), and a control group (Group 3) made of 30 subjects with advanced fibrosis (F3-F4), all with available MRE. LSM was measured in each subject along with assessment of hepatic morphological features of cirrhosis and signs of portal hypertension. The significance of t…
Charles Nodier, Trilogie écossaise
2013
Charles Nodier’s summer ambulations through Scotland in 1821 were to spawn a genre: the romantic travelogue. The reader is invited on a journey through age-old legends and oneiric cartography, through the fogs of ancient Caledonia and modern Scotland, and into the land of goblins and fairies.
Fonemātisko procesu pilnveide logoritmikas nodarbībās 4 – 5 gadus veciem bērniem ar fonētiski fonemātiskiem traucējumiem
2015
Diplomdarba autore: Zane Upeniece Zinātniskā darba vadītāja: profesote, Dr.paed . Sarmīte Tūbele Diplomdarba tēma. „Fonemātisko procesu pilnveide logoritmikas nodarbībās 4 – 5 gadus veciem bērniem ar fonētiski fonemātiskiem traucējumiem”. Darba mērķis. Teorētiski izzināt, praktiski pētīt fonemātisko procesu pilnveidi logoritmikas nodarbībās Mērķa realizēšanas uzdevumi: 1.Analizēt zinātnisko, psiholoģisko, pedagoģisko, logopēdisko un metodisko literatūru problēmas skatījumā. 2. Analizēt logoritmikas nodarbības fonemātisko procesu pilnveidei. 3. Veikt pētījumu par logoritmikas nodarbību izmantošanu fonemātisko procesu pilnveidē. Darbs sastāv no 3 nodaļām. Pirmajā nodaļā pētīta literatūra par …
Priekšējo mēleņu (S, Z, Š, Ž) izrunas traucējumu korekcija logopēdijas nodarbībās vecākā pirmsskolas vecuma bērniem
2018
Kvalifikācijas darba tēma ir “Priekšējo mēleņu (S, Z, Š, Ž) izrunas traucējumu korekcija logopēdijas nodarbībās vecākās pirmsskolas vecuma bērniem. Darba mērķis - teorētiski un praktiski izzināt līdzskaņu S, Z, Š, Ž izrunas traucējumu novēršanas iespējas logopēdijas nodarbībās. Darbs sastāv no divām daļām – teorētiskās un praktiskās daļas. Teorētiskajā daļa tiek analizēta skaņu izrunas traucējumi, vecākā pirmsskolas vecuma bērnu vecumposma likumsakarības, priekšējo mēleņu S, Z, Š, Ž izrunas traucējumu novēršana logopēdijas nodarbībās dažādu autoru skatījumā. Ir sniegts skaņu izrunas traucējumu skaidrojums pedagogu, psihologu un logopēdu atziņās, atklātas vecākā pirmskolas vecuma bērnu atmiņ…