Search results for "Nose"
showing 10 items of 1793 documents
Targeting cells of the immune system: mannosylated HPMA–LMA block-copolymer micelles for targeting of dendritic cells
2016
Background: Successful tumor immunotherapy depends on the induction of strong and sustained tumor antigen-specific immune responses by activated antigen-presenting cells (APCs) such as dendritic cells (DCs). Since nanoparticles have the potential to codeliver tumor-specific antigen and DC-stimulating adjuvant in a DC-targeting manner, we wanted to assess the suitability of mannosylated HPMA-LMA block polymers for immunotherapy. Materials & methods: Fluorescence-labeled block copolymer micelles derived from P(HPMA)-block-P(LMA) copolymers and according statistical copolymers were synthesized via RAFT polymerization, and loaded with the APC activator L18-MDP. Both types of copolymers wer…
Tracking the structural dynamics of proteins in solution using time-resolved wide-angle X-ray scattering
2008
We demonstrate tracking of protein structural changes with time-resolved wide-angle X-ray scattering (TR-WAXS) with nanosecond time resolution. We investigated the tertiary and quaternary conformational changes of human hemoglobin under nearly physiological conditions triggered by laser-induced ligand photolysis. We also report data on optically induced tertiary relaxations of myoglobin and refolding of cytochrome c to illustrate the wide applicability of the technique. By providing insights into the structural dynamics of proteins functioning in their natural environment, TR-WAXS complements and extends results obtained with time-resolved optical spectroscopy and X-ray crystallography.
Electrochemical Tantalum Oxide for Resistive Switching Memories
2017
Redox-based resistive switching memories (ReRAMs) are strongest candidates for the next-generation nonvolatile memories fulfilling the criteria for fast, energy efficient, and scalable green IT. These types of devices can also be used for selector elements, alternative logic circuits and computing, and memristive and neuromorphic operations. ReRAMs are composed of metal/solid electrolyte/metal junctions in which the solid electrolyte is typically a metal oxide or multilayer oxides structures. Here, this study offers an effective and cheap electrochemical approach to fabricate Ta/Ta2O5-based devices by anodizing. This method allows to grow high-quality and dense oxide thin films onto a metal…
Cellulose-inorganic hybrids of strongly reduced thermal conductivity
2022
Abstract The employment of atomic layer deposition and spin coating techniques for preparing inorganic-organic hybrid multilayer structures of alternating ZnO-CNC layers was explored in this study. Helium ion microscopy and X-ray reflectivity showed the superlattice formation for the nanolaminate structures and atomic force microscopy established the efficient control of the CNCs surface coverage on the Al-doped ΖnO by manipulating the concentration of the spin coating solution. Thickness characterization of the hybrid structures was performed via both ellipsometry and X-ray reflectivity and the thermal conductivity was examined by time domain thermoreflectance technique. It appears that ev…
Fourth order cascaded Raman shift in As38Se62 chalcogenide suspended core fiber pumped at 1.995 μm
2011
Fourth order cascaded Raman wavelength shift is demonstrated in As 38 Se 62 suspended core fiber using 1995 nm nanosecond source. The measured Raman gain coefficient is∼2×10−11 m/W at 1995 nm. The Raman peaks are reproduced by numerical simulations.
Tapering photonic crystal fibres for supercontinuum generation with nanosecond pulses at 532nm
2008
Experimental results on supercontinuum generation in photonic crystal fibre tapers using pump pulses of 7 ns duration at 532 nm are presented. Photonic crystal fibre tapers with the first wavelength of zero dispersion around 532 nm were fabricated. The generation of supercontinuum was investigated in normal and anomalous dispersion regimes. Supercontinuum spectra spanning more than 400 nm in the visible region are reported.
CNT-based RFID passive gas sensor
2011
Summary form only given, as follows. Single-wall carbon nanotube (CNT) is examined for the design of a passive and maintenance-free wireless RFID sensor. CNT buckypaper is characterized from a dielectric and a sensitivity point of view, using an indirect way, by using antenna measurement and simulations in a controlled medium. A CNT-based prototype RFID tag is then described as the featured maintenance free sensor and experimentally verified for its applicability and sensitivity towards NH3.
Tapa Mbuti. Antropologia dell'astratto
2008
Analisi del sistema grafico delle cortecce battute dei Pigmei Mbuti in relazione ai fenomeni edoptici e all'arte paleolitica.
MEDIATING ROLE OF DISSOCIATION SYMPTOMS BETWEEN ADOLESCENT COMPULSIVE INTERNET USE ACROSS TIME
2020
The aim of this study was to examine adolescent compulsive internet use (CIU) across a one-year period, to examine associations with symptoms of depression, anxiety and dissociation, as well as to analyze the potential mediating effect of dissociation symptoms. Previous studies have indicated that dissociation might serve as a coping strategy and/or as a consequence of problematic internet use. Participating in the study were 80 adolescents (39 girls and 41 boys), ages from 12 to 18 (mean age 14.90 years) at the time of the first measurement. At Time 1 and one year later at Time 2 measurement points the participants completed the Trauma Symptom Checklist (Briere, 1995) and items from the …
Los efectos a largo plazo de las competencias emocionales y la autoestima sobre los síntomas internalizantes de los adolescentes
2021
Internalizing symptoms such as depressive mood, somatic complaints and anxiety among adolescents are a major and global concern for parents, educators and professionals. Empirical research suggests that high level of self-esteem during adolescents is associated with psychological adjustment and emotional well-being. This study examines self-esteem as a potential mediator in the interplay between emotional competencies and internalizing symptoms during adolescence. Self-report data from 855 Spanish adolescents (Mage = 13.6, SD = 1.09, 52% girls) were collected in two waves, using a longitudinal design. The mediation model was estimated using structural equation modelling (SEM). Results show …