Search results for "OLED"

showing 10 items of 349 documents

MetProc: Separating Measurement Artifacts from True Metabolites in an Untargeted Metabolomics Experiment

2019

High-throughput metabolomics using liquid chromatography and mass spectrometry (LC/MS) provides a useful method to identify biomarkers of disease and explore biological systems. However, the majority of metabolic features detected from untargeted metabolomics experiments have unknown ion signatures, making it critical that data should be thoroughly quality controlled to avoid analyzing false signals. Here, we present a postalignment method relying on intermittent pooled study samples to separate genuine metabolic features from potential measurement artifacts. We apply the method to lipid metabolite data from the PREDIMED (PREvención con DIeta MEDi-terránea) study to demonstrate clear remova…

0301 basic medicinePooled QC sampleComputer scienceComputational biology01 natural sciencesBiochemistryArticle03 medical and health sciencesMetabolomicsTandem Mass SpectrometryMetabolomicsUntargeted metabolomics010401 analytical chemistryGeneral ChemistryPotential measurementMeasurement artifactLipidsPredimed0104 chemical sciencesR package030104 developmental biologyUntargeted metabolomicsMetabolomeArtifactsMETABOLIC FEATURESBiomarkersMissing patternChromatography LiquidJournal of Proteome Research
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Current advances in γδ T cell-based tumor immunotherapy

2017

γδ T cells are a minor population (~5%) of CD3 T cells in the peripheral blood, but abound in other anatomic sites such as the intestine or the skin. There are two major subsets of γδ T cells: those that express Vd1 gene, paired with different Vγ elements, abound in the intestine and the skin, and recognize the major histocompatibility complex (MHC) class I-related molecules such as MHC class I-related molecule A, MHC class I-related molecule B, and UL16-binding protein expressed on many stressed and tumor cells. Conversely, γδ T cells expressing the Vδ2 gene paired with the Vγ9 chain are the predominant (50-90%) γδ T cell population in the peripheral blood and recognize phosphoant…

0301 basic medicinelcsh:Immunologic diseases. AllergyAdoptive cell transferadoptive transferT cellImmunologyReviewBiologyMajor histocompatibility complexγδ T cells03 medical and health sciencesInterleukin 210302 clinical medicineAdoptive transfer; Immunoevasion; Immunotherapy; Zoledronate; γδ T cells; Immunology and Allergy; ImmunologyMHC class ImedicineCytotoxic T cellImmunology and AllergyAdoptive transfer Immunoevasion Immunotherapy Zoledronate γδ T cellsGamma delta T cellγδ T cellMHC restriction030104 developmental biologymedicine.anatomical_structureImmunologybiology.proteinimmunoevasionimmunotherapylcsh:RC581-607030215 immunologyZoledronate
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Treatment of multiple myeloma-related bone disease

2021

In this Policy Review, the Bone Working Group of the International Myeloma Working Group updates its clinical practice recommendations for the management of multiple myeloma-related bone disease. After assessing the available literature and grading recommendations using the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) method, experts from the working group recommend zoledronic acid as the preferred bone-targeted agent for patients with newly diagnosed multiple myeloma, with or without multiple myeloma-related bone disease. Once patients achieve a very good partial response or better, after receiving monthly zoledronic acid for at least 12 months, the treating…

0301 basic medicinemedicine.medical_specialtyBone Density Conservation AgentBone disease03 medical and health sciences0302 clinical medicineSpinal cord compressionmedicineHumansMultiple myelomaBone Density Conservation Agentsbusiness.industrymedicine.diseaseSurgeryDiscontinuationTransplantationBone Density Conservation Agents030104 developmental biologyZoledronic acidDenosumabOncology030220 oncology & carcinogenesisPractice Guidelines as TopicBone DiseasesbusinessBone DiseaseMultiple Myelomamedicine.drugHumanThe Lancet Oncology
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Cost-effectiveness of buffered soluble alendronate 70 mg effervescent tablet for the treatment of postmenopausal women with osteoporosis in Italy

2021

Summary The use of buffered soluble alendronate 70 mg effervescent tablet, a convenient dosing regimen for bisphosphonate therapy, seems a cost-effective strategy compared with relevant alternative treatments for postmenopausal women with osteoporosis aged 60 years and over in Italy. Introduction To assess the cost-effectiveness of buffered soluble alendronate (ALN) 70 mg effervescent tablet compared with relevant alternative treatments for postmenopausal osteoporotic women in Italy. Methods A previously validated Markov microsimulation model was adjusted to the Italian healthcare setting to estimate the lifetime costs (expressed in €2019) per quality-adjusted life-years (QALY) of buffered …

0301 basic medicinemedicine.medical_specialtyeconomic evaluationCost effectivenessCost-Benefit AnalysisEndocrinology Diabetes and Metabolismmedicine.medical_treatmentOsteoporosisUrology030209 endocrinology & metabolismAlendronate . Buffered soluble alendronate . Cost-effectiveness . Economic evaluation . Effervescent tablets . Osteoporosis . TreatmentAlendronate; Buffered soluble alendronate; Cost-effectiveness; Economic evaluation; Effervescent tablets; Osteoporosis; Treatment; Aged; Alendronate; Cost-Benefit Analysis; Female; Humans; Italy; Middle Aged; Observational Studies as Topic; Postmenopause; Quality-Adjusted Life Years; Tablets; Bone Density Conservation Agents; Osteoporosis; Osteoporosis Postmenopausal03 medical and health sciences0302 clinical medicinemedicineHumansEffervescent tabletOsteoporosis PostmenopausalAgedBone mineralPostmenopausal womenBone Density Conservation AgentstreatmentAlendronatebusiness.industrybuffered soluble alendronateMiddle AgedBisphosphonatemedicine.diseaseosteoporosisPostmenopauseObservational Studies as TopicDenosumabZoledronic acidItalyeffervescent tabletsPostmenopausalFemaleOriginal ArticleCost-effectivenessQuality-Adjusted Life Years030101 anatomy & morphologybusinessTabletsmedicine.drugOsteoporosis International
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Pooled analysis of monocyte distribution width in subjects with SARS‐CoV‐2 infection

2021

2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Clinical BiochemistryLetter to the EditorsMonocytesLeukocyte CountMDWmedicineDistribution (pharmacology)Humansmonocyte distribution widthLetter to the EditorCell SizeBiochemistry medicalbusiness.industrySARS-CoV-2MonocyteBiochemistry (medical)COVID-19Meta-analysis monocyte distribution width MDW SARS-CoV-2HematologyGeneral MedicinePrognosisVirologyMeta-analysisPooled analysismedicine.anatomical_structurebusinessInternational Journal of Laboratory Hematology
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Presepsin value predicts the risk of developing severe/critical COVID-19 illness: results of a pooled analysis

2021

2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)business.industryCritical IllnessSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Biochemistry (medical)Clinical BiochemistrycoronavirusLipopolysaccharide ReceptorsCOVID-19General Medicinemedicine.disease_causeVirologyPeptide FragmentsCOVID-19 biomarkers coronaviruspresepsinC-Reactive ProteinPooled analysispresepsinHumansMedicinebusinessValue (mathematics)BiomarkersCoronavirusClinical Chemistry and Laboratory Medicine (CCLM)
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Mujer y representación política institucional en la Comunidad Valenciana. 1977-1995. Diputadas, ministras y cargos institucionales

2014

“Mujer y representación política institucional en la Comunidad Valenciana. 1977-1995. Diputadas, ministras y cargos institucionales” es la primera parte de un trabajo de documentación para un capítulo de “La democracia en la Comunidad Valenciana. Partidos, elites políticas, elecciones y programas políticos”. “Mujer, poder político y democracia paritaria”. Se recoge el papel de la mujer en la vida política de la Comunidad Valenciana en la democracia actual, desde 1977. Es documentación sin elaborar, pero que aporta datos de la presencia de la mujer en las instituciones, partidos y sindicatos. Cuando este completa será una parte de la investigación referida, y de la que ya hay dos publicacion…

:CIENCIA POLÍTICA [UNESCO]UNESCO::HISTORIAUNESCO::CIENCIA POLÍTICA:HISTORIA [UNESCO]Dolores Ibarruri Pasionaria. Josefina López Sanmartín PCE. Ciprià Císcar Casabán. Pilar Brabo Castells. Palmira Pla Pechoviento. Adela Pla Pastor. democracia paritaria. Asunción Cruañes Molina. Carmen Alborch Bataller. Maria A. Armengol Criado. Clementina Rodenas Villena. Rita Barberá Nolla. Irma Simón Calvo. Teresa Sempere Jaén. Ofelia Soler Nomdedeu. María C. Díaz Villanueva. María Carmen Pardo Raga. Eva María Amador Guillén. Presentación Urán González. María Isabel Díez de la Lastra Barbadillo. Elena Irene Martín Crevillén. María Enriqueta Seller Roca de Togores. María Carmen Pardo Raga. Eva María Amador Guillén. María J. Mora Devis. Olga Mulet Torres. Margarita Pin Arboledas. Juana Serna Masiá. Leire Pajín Iraola. Rosa M. Peris Cervera. Amparo Ferrando. Carmen Arjona. María I. España Moya. Federica Montseny Mañé. Matilde Fernández Sanz. Rosa Conde Gutiérrez del Álamo. María de los Ángeles Amador Millán. Cristina Alberdi Alonso. Margarita Mariscal de Gante Mirón. Esperanza Aguirre Gil de Biedma. Loyola de Palacio del Valle-Lersundi. Isabel Tocino Biscarolasaga. Pilar del Castillo Vera. Celia Villalobos Talero. Anna María Birulés Beltrán Ana Pastor. Ana de Palacio del Valle-Lersundi. Elvira Rodríguez Herrero. Julia García-Valdecasas. Ana Mª Castellanos Vilar. Elena Mª Martín Yánez. Paloma Gómez Osorio. Concepción Pérez Morales. Francisca Benabent Fuentes. Carmen Monzó Juan. Rosa Mª Morte Julián. Gloria Marcos Martí. Lourdes Alonso Belza. Pilar Pedraza. María García-Lliberos Sánchez-Robles. Blanca Blanquer. Dolors Giner Duran. Teresa Fluvía Rodríguez. Trinidad Simó. Emilia Noguera. Hortensia Moriones Almaraz. Carolina García Mahiques. Hortensia Moriones Almaraz. Juana Serna Maciá. Lourdes Alonso Belza. Inmaculada Rodríguez-Piñero Fdez. Carmen Macián Armengod. Carmen Moya García. María José López Rodenas. María Juan Millet. Alicia de Miguel García. Ana Encabo Balbín. Ana Michavila Nuñez. Isabel Villalonga Campos. Carmen Dolz Adell. Eva Maria Amador Guillen. Alida C. Mas Taberner. Dora Ibars Sancho. Amparo Koninckx Frasquet. Blanca Martínez de Vallejo Fuster. Consuelo Císcar Casabán. Auxiliadora Hernández Miñana. Silvia Caballer Almela. Gemma Amor Pérez. Emma Iranzo Martín. Cristina Serrano Mateo. Cristina Santamarina Ciurana
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Un aspecto de la polémica gongorina: la lengua de las Soledades y el Polifemo como discutido criterio de corrección

2008

22 p. Maquieira Rodríguez, Marina A.. Un aspecto de la polémica gongorina: la lengua de las Soledades y el Polifemo como discutido criterio de corrección. En: Quaderns de filologia. Estudis lingüístics, 2008, No. 13. Dedicado a: Historiografía lingüística hispánica: 135 SI

:LINGÜÍSTICA [UNESCO]Góngora y Argote Luis de 1561-1627. SoledadesLingüísticaFilologíasGrupo BPolémicaGóngora y Argote Luis de1561-1627. El PolifemoUNESCO::LINGÜÍSTICAFilologías hispánicas
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Ab Initio Studies of Triplet-State Properties for Organic Semiconductor Molecules

2012

Triplet–triplet annihilation (TTA) leads to a reduced efficiency of organic light-emitting diodes (OLEDs) at high current densities. Spacial confinement of the triplet excitons, which is mainly dependent on triplet energy differences, can reduce the TTA rate. Therefore, a deliberate choice of the organic semiconductor materials with particular attention to their triplet energies can help to considerably increase the device efficiency. Organic solid-state lasers are, on the other hand, efficiently quenched by singlet–triplet annihilation (STA), which is closely related to the triplet–triplet absorption of the organic semiconductors. To establish a useful set of parameters related to the proc…

Absorption spectroscopyChemistryExcitonAb initio02 engineering and technology010402 general chemistry021001 nanoscience & nanotechnology7. Clean energy01 natural sciences0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsOrganic semiconductorGeneral EnergyChemical physicsComputational chemistryOLEDMoleculePhysical and Theoretical ChemistryTriplet state0210 nano-technologyAbsorption (electromagnetic radiation)The Journal of Physical Chemistry C
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Trap-limited mobility in space-charge limited current in organic layers

2009

Space-charge limited current transport in organic devices, relevant to the operation of a range of organic optoelectronic devices, is analyzed in the frequency domain. The classical multiple trapping picture with one transport state and one trap level is used as the basis for the descriptions. By varying the energetic and kinetic properties of the traps, we show that the admittance and the capacitance spectra are considerably modified depending on the interplay between the trap-limited mobility and the trap kinetics. We point out that capacitance steps at low-frequency, usually found in experiments, are observed only for slow traps. © 2008 Elsevier B.V. All rights reserved.

AdmittanceCapacitanceTrappingCapacitanceBiomaterialsTrap (computing)OpticsMaterials ChemistryOLEDPhysics::Atomic PhysicsElectrical and Electronic EngineeringElectrical impedanceMobilityCondensed Matter::Quantum GasesOrganic electronicsChemistrybusiness.industryImpedanceGeneral ChemistryCondensed Matter PhysicsSpace chargeTrapElectronic Optical and Magnetic MaterialsOLEDChemical physicsTransport in organic materialsbusinessOrganic Electronics
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