Search results for "ONJ"

Biological Peer-To-Peer Networks: From Bacterial Communication To The Development Of Synthetic Distributed Systems

2014

We address Bacterial Computing from the study of bacterial communication mechanisms, by assuming a conceptual framework between Computer Science and Biology in which cells are conceived as nodes. This nodes process information through modules formed of DNA as encoded software (biobricks) and are connected to other nodes. In order to understand how peerto-peer mechanisms operate in bacteria, we have studied Quorum sensing and Conjugation with an engineering perspective. Learning how cells process and exchange information we try to glimpse new theoretical approaches to develop synthetic networks and to transfer complex algorithms to natural environments. Extending bacterial communications we …

Latvijas Vēstures Institūta Žurnāls. 2022, Nr. 1 (115)

2022

LU Latvijas vēstures institūta LU ilgtermiņa saistību izpildei 2020.-2022. g. ("Latvijas Vēstures Institūta Žurnāls")

Modelos y algoritmos de predicción fuzzy

2019

En un mundo tan globalizado la complejidad macro-económica, la volatilidad en los mercados y la estabilidad político-social de un país, afectan directamente a las cotizaciones de los valores bursátiles del país de referencia y añaden complejidad a la toma de decisiones. La riqueza de un análisis o inferencia sobre las cotizaciones de valores en mercados bursátiles tiene que servir como soporte para la toma de decisiones, por lo que no sólo han de basarse en una predicción puntual, de ahí radica la gran relevancia de las series temporales difusas. Ya que las series temporales difusas pueden tratar entornos donde hay incertidumbre en los datos (comportamientos o relaciones entre los datos) y/…

Surface plasmon resonance signal enhancement based on erlotinib loaded magnetic nanoparticles for evaluation of its interaction with human lung cance…

2021

Abstract Surface plasmon resonance (SPR) sensor provides a very useful tool based on its label-free, real-time monitoring and low price properties. However, measurement of small molecules and extremely diluted analytes is difficult and therefore, signal enhancement is required. In the present study, signal enhancement of erlotinib conjugated magnetic nanoparticles (erlotinib-MNPs) compared to erlotinib was evaluated via their interaction with overexpressed epidermal growth factor receptor on human lung cancer cells (A549 cell line) surface using SPR sensor at three temperature levels. The attained results showed an average signal amplification of about 2.5-fold for MNP-erlotinib interaction…

1-Aminocyclopropane-1-Carboxylic Acid, its Malonyl Conjugate and 1-Aminocyclopropane-1-Carboxylate Synthase Activity in Needles of Damaged and Undama…

1994

Summary Levels of free 1-aminocyclopropane-1-carboxylic acid (ACC), its malonyl conjugate (MACC) and ACC-synthase activity were significantly higher in the needles of damaged Norway spruce trees ( Picea abies (L.) Karst ) compared with those in undamaged trees during both the diurnal and seasonal courses. The concentrations of ACC and MACC, and ACC-synthase activity fluctuated much more intensively in the needles of damaged trees both in the diurnal and the seasonal courses than in those of undamaged ones, which implies that damaged trees respond more sensitively to the environmental conditions. ACC concentrations were the highest in summer and lowest in fall, while MACC concentrations seem…

Quitter l’enseignement : un révélateur des transformations du métier dans le premier degré

2022

Principal Poincar\'e Pontryagin Function associated to some families of Morse real polynomials

2014

It is known that the Principal Poincar\'e Pontryagin Function is generically an Abelian integral. We give a sufficient condition on monodromy to ensure that it is an Abelian integral also in non generic cases. In non generic cases it is an iterated integral. Uribe [17, 18] gives in a special case a precise description of the Principal Poincar\'e Pontryagin Function, an iterated integral of length at most 2, involving logarithmic functions with only one ramification at a point at infinity. We extend this result to some non isodromic families of real Morse polynomials.

Non-archimedean hyperbolicity and applications

2018

Inspired by the work of Cherry, we introduce and study a new notion of Brody hyperbolicity for rigid analytic varieties over a non-archimedean field $K$ of characteristic zero. We use this notion of hyperbolicity to show the following algebraic statement: if a projective variety admits a non-constant morphism from an abelian variety, then so does any specialization of it. As an application of this result, we show that the moduli space of abelian varieties is $K$-analytically Brody hyperbolic in equal characteristic zero. These two results are predicted by the Green-Griffiths-Lang conjecture on hyperbolic varieties and its natural analogues for non-archimedean hyperbolicity. Finally, we use …

What happens to the BRONJ patients when re-classified according to the novel SICMF-SIPMO recommendations? Our experience

2014

Background. Since 2009, according to the American Association of Oral and Maxillofacial Surgeons staging system (AAOMS-SS), Bisphosphonate Related Osteonecrosis of the Jaw (BRONJ) has been defined by the presence of bone exposition; in absence of this condition, patients presenting other unspecific clinical and/or radiological signs of disease were classified into the “stage 0”. In 2012, the Italian Society of Maxillo-Facial Surgery (SICMF) and the Italian Society of Oral Pathology and Medicine (SIPMO) redefined BRONJ, as an adverse drug event, with several clinical forms (exposed and not-exposed), and updated the staging system, abolishing the stage 0. Aim of this study was to re-classify …

The combination of laser-assisted surgery with PRP for the treatment of BRONJ in cancer patient. A pilot study

2014

Aim. Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a well-known potential complication of bisphosphonates (BPs) therapy and its treatment could reckon on different approaches. Recently, encouraging results for BRONJ were showed from some clinical studies using Er, Cr: YSGG laser-assisted surgery. Platelet-Rich Plasma (PRP), a new approach to promote tissue regeneration and healing, may be a promising complementary therapy. The aim of this pilot study is to study the effectiveness, in terms of clinical healing, of a combined treatment (laserassisted surgery and topical PRP) for BRONJ in a group of cancer patients. Methods. Ten oncological patients (3 males, 7 females; aged 69-89…