Search results for "OSAS"
showing 10 items of 274 documents
El nuevo paradigma de las bibliotecas de las órdenes religiosas: el ejemplo de los franciscanos de la Inmaculada Concepción
2022
Las bibliotecas de las órdenes religiosas han sido desde su origen las depositarias de la tradición bibliográfica de la sociedad. Desde el siglo XIX con motivos de las desamortizaciones y las guerras, este tipo de fondos fue perdiendo importancia por la pérdida y expropiación de libros. En pleno siglo XXI las órdenes religiosas viven un proceso de secularización paulatino, un hecho que hace que este patrimonio esté en peligro de dispersión. Para evitar la pérdida de este patrimonio la Provincia Franciscana de la Inmaculada Concepción ha creado una red de bibliotecas franciscanas para la catalogación de los fondos y su puesta en valor. The libraries of religious orders have been since their …
'A Difficult School Text in Anglo-Saxon England: The Third Book of Abbo’s Bella Parisiacae urbis', in Leeds Studies in English 37 (2006)
2006
Si prendono in esame le glosse interlineari in inglese antico al terzo libro dei Bella Parisiacae urbis di Abbone di San Germano, attestate da due manoscritti anglosassoni. Le scelte del glossatore sono valutate alla luce delle difficoltà insite nel testo latino di Abbone, particolarmente complesso, specialmente dal punto di vista del lessico, analizzando, in particolare la resa, di analogium, anabola, abacus, abaso, baccaulus, choraula e uxorius. Le rispettive glosse anglosassoni sono esaminate nell’economia dell’intera glossatura e valutate alla luce dell’uso didattico della versione interlineare in volgare. Il numero della rivista è stato dedicato alla Prof. Joyce Hill, già professore or…
Clostridium difficile IStron CdISt1: Discovery of a Variant Encoding Two Complete Transposase-Like Proteins
2004
ABSTRACT Screening a Clostridium difficile strain collection for the chimeric element Cd ISt1 , we identified two additional variants, designated Cd ISt1 -0 and Cd ISt1 -III. In in vitro assays, we could prove the self-splicing ribozyme activity of these variants. Structural comparison of all known Cd ISt1 variants led us to define four types of IStrons that we designated Cd ISt1 -0 through Cd ISt1 -III. Since Cd ISt1 -0 encodes two complete transposase-like proteins (TlpA and TlpB), we suggest that it represents the original genetic element, hypothesized before to have originated by fusion of a group I intron and an insertion sequence element.
Impact of Insertion Sequences and RNAs on Genomic Inversions in Pseudomonas aeruginosa
2022
Abstract In this article, a bioinformatics pipeline is proposed that focuses on two types of elements, namely the mobile genetic elements (MGE) and Ribonucleic acids (RNAs). The MGEs are called insertion sequences (ISs) in the prokaryotic domain. The objective of this research work is to study the behaviour of RNAs and MGEs genes, and the effects of their presence around inversions in genome sequences. The proposed pipeline finds the relation between the transposase gene types (e.g., DDE and DEDD) located within insertion sequences according to their IS family and sub-family, and RNAs (tRNA and rRNA) on the one hand, and genomic inversion on the other hand. More precisely, we wonder whether…
Sleeping Beauty transposon system – future trend in T-cell-based gene therapies?
2006
Evaluation of: Huang X, Wilber AC, Bao L et al.: Stable gene transfer and expression in human primary T cells by the Sleeping Beauty transposon system. Blood 107, 483–491 (2006). The Sleeping Beauty (SB) transposon system can mediate stable gene transfer and expression in primary human T cells. Optimal in vitro conditions for maximum gene transfer efficiencies have been developed with regard to further application of the SB transposon system in T cell based gene therapies. This raises the question of whether or not the SB transposon system is a convincing alternative for virus-mediated gene transfer based on the currently available data. Here, we will discuss controversial safety and effic…
On the transposon origins of mammalian SCAND3 and KRBA2, two zinc-finger genes carrying an integrase/transposase domain
2012
SCAND3 and KRBA2 are two mammalian proteins originally described as “cellular-integrases” due to sharing of a similar DDE-type integrase domain whose origin and relationship with other recombinases remain unclear. Here we perform phylogenetic analyses of 341 integrase/transposase sequences to reveal that the integrase domain of SCAND3 and KRBA2 derives from the same clade of GINGER2, a superfamily of cut-and-paste transposons widely distributed in insects and other protostomes, but seemingly absent or extinct in vertebrates. Finally, we integrate the results of phylogenetic analyses to the taxonomic distribution of SCAND3 and KRBA2 and their transposon relatives to discuss some of the proce…
Sequences homologous to the hobo transposable element in E strains of Drosophila melanogaster.
2001
Hobo is one of the three Drosophila melanogaster transposable elements, together with the P and I elements, that seem to have recently invaded the genome of this species. Surveys of the presence of hobo in strains from different geographical and temporal origins have shown that recently collected strains contain complete and deleted elements with high sequence similarity (H strains), but old strains lack hobo elements (E strains). Besides the canonical hobo sequences, both H and E strains show other poorly known hobo-related sequences. In the present work, we analyze the presence, cytogenetic location, and structure of some of these sequences in E strains of D. melanogaster. By in situ hybr…
Problematic and non-problematic engagement in Online Sexual Activities across the lifespan
2021
During the last decade, the number of people using the Internet for sexual purposes has increased exponentially. However, most studies conducted so far have analysed Online Sexual Activity (OSA) of adolescents and young people, meaning that we have few information on how this phenomenon is expressed across the lifespan. The aim of this study was to analyse three aspects of OSA (prevalence of different OSAs, motives to engage in OSA, and excessive and problematic engagement in OSA) in a large sample of individuals in different developmental stages. A self-selected sample of 8040 individuals between 12 and 85 years old were recruited and completed an online survey. Participants were distribut…
Social representations of latin american immigrants about immigration, care and elderly caregivers
2013
Ageing in Spain has increased considerably and elderly people often find themselves in a situation of great dependence. Facing this situation, many have had the support of immigrant caregivers from Latin America. This research had the purpose to know the social representations (SR) of these caregivers, living in Valencia (Spain), about immigration, care and elderly care. It involved the participation of 35 immigrants who responded the Word Association Test and a socio-demographic questionnaire. The results revealed that the SR on immigration reflect "nostalgia", care was represented by "help", and care for the elderly by "respect". It is concluded that the SR allow understanding the symboli…