Search results for "OUTCOME"

Adolescent and Young Adult Cancer Survivors: Design and Characteristics of the First Nationwide Population-Based Cohort in Italy

2020

Purpose: Adolescent and young adult (AYA, 15-39 years) cancer survivors (alive at least 5 years after cancer diagnosis) are less studied than younger and older cancer survivors and research on their late effects is limited. To facilitate research on long-term outcomes of AYA cancer survivors, we established, in Italy, a population-based AYA cancer survivors' cohort. This article describes the study design and main characteristics of this cohort. Methods: The cohort derives from population-based cancer registries (CRs). Each CR identified AYA cancer patients retrospectively. Treatment for first primary cancer and all health events from diagnosis to death can be traced through linkage with av…

Translating recent results from the Cardiovascular Outcomes Trials into clinical practice: recommendations from the Central and Eastern European Diab…

2017

Aims These recommendations aim to improve care for patients with type 2 diabetes (T2D) at high cardiovascular (CV) risk in Central and Eastern Europe. Cardiovascular disease (CVD) and/or chronic kidney disease (CKD) are major interdependent comorbidities in patients with T2D, accounting for 50% of mortality. Following recent CV outcomes trial (CVOT) results, including those from EMPA-REG OUTCOME®, LEADER®, SUSTAIN™-6 and, most recently, the CANVAS study, it is essential to develop regional expert consensus recommendations to aid physicians in interpreting these newest data to clinical practice. Methods The Central and Eastern European Diabetes Expert Group (CEEDEG) followed a Delphi method …

Use of Antihypertensive Drugs During Preeclampsia

2018

Treatment of pregnancy-related hypertensive disorders, such as preeclampsia (PE), remain a challenging problem in obstetrics. Typically, aggressive antihypertensive drug treatment options are avoided to prevent pharmacological-induced hypotension. Another major concern of administering antihypertensive drugs during pregnancy is possible adverse fetal outcome. In addition, management of hypertension during pregnancy in chronic hypertensive patients or in patients with prior kidney problems are carefully considered. Recent studies suggest that PE patients are at increased cardiovascular risk postpartum. Therefore, these patients need to be monitored postpartum for the subsequent development o…

Characteristics of clinical trials in rare vs. common diseases: A register-based Latvian study.

2017

Background Conducting clinical studies in small populations may be very challenging; therefore quality of clinical evidence may differ between rare and non-rare disease therapies. Objective This register-based study aims to evaluate the characteristics of clinical trials in rare diseases conducted in Latvia and compare them with clinical trials in more common conditions. Methods The EU Clinical Trials Register (clinicaltrialsregister.eu) was used to identify interventional clinical trials related to rare diseases (n = 51) and to compose a control group of clinical trials in non-rare diseases (n = 102) for further comparison of the trial characteristics. Results We found no significant diffe…

THE CHALLENGE OF OPEN TIBIAL SHAFT FRACTURES: WHEN TOMANAGE WITH EXTERNAL FIXATION AND WHEN TO USEINTRAMEDULLARY NAILING?

2020

Treatment of open tibial shaft fractures is challenging. External fixation (EF) is comparatively safe in treating these open injuries with the main advantages of easy application, minimal additional disruption, and convenient subsequent soft tissue repair. Tibial intramedullary nailing (IM) is optimal for the treatment of open tibial fractures. This study aims to report the outcomes of our multi-center experience in the management of open tibial shaft fractures, evaluating the efficacy and safety of using either the external fixation (EF) or intramedullary nailing (IM).In this study, clinical-radiographic results were evaluated in 26 cases of open fractures treated with an external fixator …

Revisiting the Salt Lake City Olympic scandal: Would the outcome be different today?

2016

Many international sport organizations face bribery scandals resulting from its event bidding process. The International Olympic Committee (IOC) faced this type of scandal with the 2002 Olympic Winter Games. Two members of the Salt Lake City Organizing Committee (SLOC) faced 15 criminal charges from providing more than US$1.2 million in cash and gifts to entice IOC members to support its bid. Ultimately both SLOC members were acquitted of all charges. Can a new interpretation of the United States’ anti-bribery law, the Foreign Corrupt Practices Act (FCPA), be effective in preventing similar sport scandals? peerReviewed

Finnish Experiences of Oecd’s International Assessment of Higher Education Learning Outcomes (ahelo)

2015

The aim of this article is to describe the implementation of International Assessment of Higher Education Learning Outcomes (AHELO) in Finland and to highlight ethical considerations of large-scale international assessments. The Finnish results of the AHELO feasibility study show that a fully-fledged project is possible to carry if special attention is paid to the participation of students in test sessions, if enough time is reserved for the implementation phase and if scoring of open-ended questions is carefully carried out and monitored.It is, however, important that large-scale international assessmentssuch as AHELO do not start to colonialise and converge understandings of what is consi…

The learning outcomes approach in formal second chance education

2015

Promocijas darbs pieaugušo pedagoģijā „Mācīšanās rezultātu pieeja formālajā otrās iespējas izglītībā” tika izstrādāts Latvijas Universitātes Pedagoģijas, psiholoģijas un mākslas fakultātē laika posmā no 2009. līdz 2014.gadam. Darba izstrādi vadīja Dr. habil. paed., profesore Irina Maslo. Darba mērķis ir izpētīt saiknes starp mācīšanās rezultātu pieeju un pedagoģisko praksi formālās otrās iespējas izglītībā, noteikt analītiskajos pierādījumos pamatotus faktus par šķēršļiem un iespējām, ar kurām mācīšanās procesā sastopas pieaugušie (kas nav ieguvuši attiecīgo izglītību). Darbā ir 204 lappuses, un tas sastāv no ievada, trīs nodaļām, literatūras saraksta un desmit pielikumiem. Pētījumā izmanto…

Mode Effect in Large-Scale Assessment

2017

Yhdeksäsluokkalaisten opiskelukäytänteet englannin, ruotsin ja ranskan oppitunneilla ja vapaa-ajalla

2016

The article reports on a quantitative investigation of the differences in Finnish 15–16 year- old students’ self-reported foreign/second language (L2) study practices and use across three languages: English (n=3,476), Swedish (n=1,679), and French (n=1,023). The data set consisted of (a) a questionnaire about students’ background and L2 study practices/use and (b) their L2 speaking and writing proficiency. The differences between the languages were generally small although the students reported to do their homework in Swedish considerably less regularly than in English and French and English was used more outside classroom than Swedish and French. The differences in the background variables…