Search results for "Omega-3"
showing 10 items of 106 documents
Effects of a nutraceutical formulation based on the combination of antioxidants and ω-3 essential fatty acids in the expression of inflamma…
2013
Maria D Pinazo-Durán,1,* Carmen Galbis-Estrada,1,* Sheila Pons-Vázquez,1 Jorge Cantú-Dibildox,2 Carla Marco-Ramírez,1 Javier Benítez-del-Castillo21Ophthalmic Research Unit Santiago Grisolia, Department of Surgery/Ophthalmology, Faculty of Medicine, University of Valencia, Valencia, Spain; 2Department of Ophthalmology, Hospital of Jerez, Jerez de la Frontera, Spain*These authors contributed equally to this workBackground: Women, and those older than 65 years of age, are particularly susceptible to dry eye disorders (DEDs). Inflammation is clearly involved in the pathogenesis of DEDs, and there is mounting evidence on the antioxidant and …
Moderate intake of n-3 fatty acids is associated with stable erythrocyte resistance to oxidative stress in hypertriglyceridemic subjects.
2001
Background The important triacylglycerol-lowering capacity of n-3 fatty acids is counterbalanced by their inherent sensitivity to oxidation. Inconsistent results about the latter have been reported in hypertriglyceridemic individuals. After incorporation into cell membranes, n-3 fatty acids may alter membrane-related functions. In view of the distinct composition of hypertriglyceridemic membranes and the prooxidant status in this condition, it can be surmised that cell enrichment with the oxidizable n-3 fatty acids will be associated with an increased hemolytic process. Objective We sought to evaluate the effect of fish oil consumption on n-3 fatty acid incorporation into erythrocyte membra…
Effect of fish oil on LDL oxidation and plasma homocysteine concentrations in health.
2003
Oxidation of low-density lipoprotein (LDL) and hyperhomocysteinemia are believed to play a role in therogenesis. Whether n-3 polyunsaturated fatty acids increase LDL susceptibility to oxidation or influence homocysteine (Hcy) metabolism has long been a subject of controversy. In this study, we evaluated the effect of 8 weeks of dietary supplementation with 6 g/day of fish oil (FO; 3 g of n-3 fatty acids) on plasma lipoproteins, in vitro LDL peroxidation, antioxidant status, and plasma Hcy concentrations in 16 normolipidemic subjects. FO rapidly and significantly (P < .01) decreased plasma total and very low density lipoprotein triglyceride concentrations and had no effect on LDL or high-den…
Ocular Surface and Tear Film Changes in Older Women Working with Computers
2015
The aim of this work is to investigate changes in the ocular surface (OS) and tear film (TF) by means of questionnaire-based subjective symptoms, TF break-up time, Schirmer test, and TF analysis in women working with computers and to analyze the effects of the oral supplementation with antioxidants/omega 3 fatty acids (A/ω3) in the OS outcomes. Women aged 40–65 years (n=148) were recruited at the Administrative Offices of Valencia (Spain) and distributed into two age groups, 40–52 years (AGE1;n=87) and 53–65 years (AGE2;n=61), and then subdivided according to being (or not) computer users (CUG; NCUG) during the workday. Homogeneous subgroups were randomly assigned (or not) to the daily inta…
Farmed Gilthead Sea Bream (Sparus aurata) by-Products Valorization: Viscera Oil ω-3 Enrichment by Short-Path Distillation and In Vitro Bioactivity Ev…
2021
This study shows a pilot scale protocol aimed to obtain an omega 3-enriched oil after the processing of farmed gilthead sea bream viscera (SBV)
Antioxidant activity and fatty acids quantification in Sicilian purslane germplasm
2019
Portulaca oleracea is an annual succulent herb in the family Portulacaceae. It is a nutritious vegetable with high antioxidant properties and, it is among the richest plant source of ω-3 fatty acids, as well as a rich source of ω-6 fatty acids, ascorbic acid, tocopherols and beta-carotene. In the present study, three purslane populations under different Mediterranean environmental conditions for two years, for future valorization as novel food sources of omega-3 fatty acids, were evaluated. In particular, biomorphological characteristics, total phenols and fatty acids content were determined. The antioxidant activities were evaluated using 2,2-diphenyl-1-picrylhydrazyl assay. The population…
Uzturs ar samazinātu ogļhidrātu saturu (SCD/GAPS) autiskā spektra simptomu mazināšanai bērniem- pilotpētījums
2019
Ar autismu saprot plaši izplatītus smadzeņu attīstības traucējumus, kuru etioloģijā būtiska ietekme ir gan vides, gan ģenētiskajiem faktoriem. Autisma izpausmes katram cilvēkam var būt ar individuālu simptomu kopumu, tāpēc biežāk runā par autiskā spektra traucējumiem (AST), ko raksturo simptomu triāde - problēmas integrēties sabiedrībā, komunikatīvie traucējumi un ierobežota, atkārtota uzvedība. Saskaņā ar CDC (Centers for Disease Control and Prevention) 2014. g. datiem ASV viens no 59 bērniem ir ar AST. Tiek vērtēts, ka Latvijā, tāpat kā Eiropā, ar AST ir katrs simtais bērns. Medicīniskajā literatūrā dominē viedoklis, ka šobrīd nav vienas terapijas, kas spētu mazināt AST pamatsimptomus. To…
High pancreatic n-3 fatty acids prevent STZ-induced diabetes in fat-1 mice: inflammatory pathway inhibition.
2011
OBJECTIVE Because of confounding factors, the effects of dietary n-3 polyunsaturated fatty acids (PUFA) on type 1 diabetes remain to be clarified. We therefore evaluated whether fat-1 transgenic mice, a well-controlled experimental model endogenously synthesizing n-3 PUFA, were protected against streptozotocin (STZ)-induced diabetes. We then aimed to elucidate the in vivo response at the pancreatic level. RESEARCH DESIGN AND METHODS β-Cell destruction was produced by multiple low-doses STZ (MLD-STZ). Blood glucose level, plasma insulin level, and plasma lipid analysis were then performed. Pancreatic mRNA expression of cytokines, the monocyte chemoattractant protein, and GLUT2 were evaluate…
Enhanced Oxidative Stress and Other Potential Biomarkers for Retinopathy in Type 2 Diabetics: Beneficial Effects of the Nutraceutic Supplements
2015
We have studied the global risk of retinopathy in a Mediterranean population of type 2 diabetes mellitus (T2DM) patients, according to clinical, biochemical, and lifestyle biomarkers. The effects of the oral supplementation containing antioxidants/omega 3 fatty acids (A/ω3) were also evaluated. Suitable participants were distributed into two main groups: (1) T2DMG (with retinopathy (+DR) or without retinopathy (−DR)) and (2) controls (CG). Participants were randomly assigned (+A/ω3) or not (−A/ω3) to the oral supplementation with a daily pill of Nutrof Omega (R) for 18 months. Data collected including demographics, anthropometrics, characteristics/lifestyle, ophthalmic examination (best cor…
Populāru uztura bagātinātāju produktu ražošanas tehnoloģiju pārskats, to sastāvu un produktu patērētāju zināšanu līmeņa izvērtējums
2022
Uztura bagātinātāji tiek definēti kā pārtikas produkti parastā uztura papildināšanai koncentrētu uzturvielu veidā. Tos pārdod “devas” formā (piemēram, tabletes, kapsulas, šķidrumi nomērītos daudzumos), lai iekļautu ikdienas uzturā. Tā kā uztura bagātinātāji ir pieskatāmi pie pārtikas produktiem un ir brīvi pieejami lietošanai ikdienā, tad ir svarīgi, lai patērētāji zinātu, kā tos lietot pareizi un droši. Bakalaura darba mērķis ir aprakstīt populāru uztura bagātinātāju ražošanas tehnoloģijas un izvērtēt to sastāvus dažādās formās, kā arī izvērtēt uztura bagātinātāju patērētāju zināšanu līmeni (piem., vai patērētāji zina par uztura bagātinātāju mijiedarbībām) un savākt informāciju par patērēt…