Search results for "Overall"
showing 10 items of 145 documents
Embryo culture: can we perform better than nature?
2010
Culture of preimplantation-stage embryos has always been a key element of laboratory embryology and has contributed substantially to the success of many assisted reproduction procedures. During the past decade, its importance has increased as extended in-vitro embryo culture and single blastocyst transfer have become indispensable parts of the approach to decreasing the chance of multiple pregnancy while preserving the overall efficiency of the treatment. However, in spite of the scientific and commercial challenge stimulating research worldwide to optimize embryo culture conditions, a consensus is missing even in the basic principles, including composition and exchange of media, the requir…
La recente riforma della disciplina italiana del subappalto nella prospettiva del bid rigging
2023
L’articolo analizza in chiave critica la disciplina nazionale del subappalto nell’ambito delle gare pubbliche, così come recentemente riformata a seguito di diversi interventi normativi in ottemperanza alla procedura d’infrazione avviata dalla Commissione UE. Stando alla tesi dell’A., l’attuale quadro normativo – caratterizzato dalla quasi totale eliminazione delle limitazioni previgenti (probabilmente anche spingendosi oltre ciò che la Commissione UE ha richiesto) – difetta nel trovare un equo bilanciamento tra il principio della massima partecipazione alla gara, da un lato, e l’esigenza di prevenire e svelare potenziali condotte collusive, dall’altro. La suddetta conclusione, peraltro, ap…
Carlo Attanasio: obblighi legali a contrarre e tutela della concorrenza
2023
L'A. passa criticamente in rassegna il Volume recensito, evidenziandone struttura e iter argomentativo. L'impianti complessivo del lavolo e la sua tesi di fondo vengono fatti oggetto di articolate obizioni; specifico risalto viene poi dedicato al terreno - pure non indagato dall?A. - dei mercati digitali
Development of the Happiness Index in a country
2016
[EN] In this paper, a Happiness Index is built through the Human Dignity Respect Index which is explained by Author (2014). The index is created using three main values: development, freedom and equality. But the equality is explained by solidarity, justice and peace. Then, the Happiness Index is developed with this five concepts. The aim of this paper is to obtain the minimum quantitative variables to explain these values as well as to obtain a generic formula, which allows measuring the happiness of a country/region. The term “generic” is introduced because this formula could be extrapolated to any country. The variables to obtain the Development Index are health (Life Expectancy at birth…
CheS-Mapper 2.0 for visual validation of (Q)SAR models
2014
Abstract Background Sound statistical validation is important to evaluate and compare the overall performance of (Q)SAR models. However, classical validation does not support the user in better understanding the properties of the model or the underlying data. Even though, a number of visualization tools for analyzing (Q)SAR information in small molecule datasets exist, integrated visualization methods that allow the investigation of model validation results are still lacking. Results We propose visual validation, as an approach for the graphical inspection of (Q)SAR model validation results. The approach applies the 3D viewer CheS-Mapper, an open-source application for the exploration of sm…
Analysis of different key behavioral patterns to score in elite taekwondoists according to the weight category and gender
2021
Traditionally, research in taekwondo has focused on athletes' overall performance considering the entire sample of the tournament or analyzed selected bouts while ignoring behavioral differences of athletes according to their gender and weight category. Thus, the aim of this study was to analyze the behavioral patterns used to score points in the London Olympic Games according to gender and weight category [fin (FW), feather (FTW), light (LW), and heavy (HW)] of the athletes. A total of 24,940 actions were analyzed by using observational methodology, a mixed method methodology where lag sequential and polar coordinate analysis were applied. Different patterns could be seen in the actions pe…
Retrospektīvs pētījums par dzīvildzi resnās zarnas vēža II stadijā, atkarībā no ārstēšanas stratēģijas
2017
Ievads: Adjuvanta ķīmijterapija pacientiem ar diagnosticētu II (UICC) stadijas resnās zarnas vēzi ir apsverama. Pacientu dalījums augsta un zema riska grupās, palīdz izlemt, vai pēc ķirurģiskas ārstēšanas ir indicēta ķīmijterapija, lai gan dzīvildzes ieguvumi nav ne plaši pētīti, nedz arī pierādīti. Tāpēc, autora mērķis šajā pētījumā bija salīdzināt piecu gadu dzīvildzi UICC II stadijas resnās zarnas vēža pacientiem, kuri saņēma adjuvantu ķīmijterapiju, un pacientiem, kuri ķīmijterapiju nesaņēma. Metodes: Dati par pacientiem ar II stadijas resnās zarnas vēzi, tika iegūti Paula Stradiņa Klīniskās universitātes slimnīcā Rīgā, Latvijā, Onkoloģijas klīnikā. Diagnozes apstiprināšanas laiks no 20…
Nab-paclitaxel in pretreated metastatic breast cancer: evaluation of activity, safety, and quality of life
2019
Rossella De Luca,1 Giuseppe Profita,2 Giuseppe Cicero1 1Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, Palermo, Italy; 2Department of Surgical, Oncological and Oral Sciences, Section of Surgical, University of Palermo, Palermo, Italy Objective: Metastatic breast cancer (MBC) is an incurable disease; the treatment of this disease prolongs survival, improving the quality of life (QoL) with a balance between efficacy and toxicity of the treatment. In recent years, treatment with nab-paclitaxel has improved the already known antitumor activity of conventional paclitaxel, in terms of increased efficacy and better tolerability. The aim o…
Analysis of ultra-triathlon performances
2011
Romuald Lepers1, Beat Knechtle2,3, Patrizia Knechtle2, Thomas Rosemann2 1INSERM U887, Faculty of Sport Sciences, University of Burgundy, Dijon, France; 2Institute of General Practice and Health Services Research, University of Zurich, Switzerland; 3Gesundheitszentrum St Gallen, St Gallen, Switzerland Abstract: Despite increased interest in ultra-endurance events, little research has examined ultra-triathlon performance. The aims of this study were: (i) to compare swimming, cycling, running, and overall performances in three ultra-distance triathlons, double Ironman distance triathlon (2IMT) (7.6 km swimming, 360 km cycling, and 84.4 km running), triple Ironman distance triathlon (3IMT) (11.…
Decomposition analysis of bioresources: Implementing a competitive and sustainable bioeconomy strategy in the Baltic Sea Region
2021
Bioeconomy development has become one of the new trends in policy design and research. This study looks at biotic resource extraction in the Baltic Sea region countries providing detailed country by country analyses of factors affecting changes in resource extraction. The study is based on the index decomposition analysis including factors related to bioeconomy strategies such as the population, share of people employed in bioeconomy, labour intensity, biotic resource extraction productivity, share of bioeconomy, export intensity, and share of bioresource export. The main factors increasing biotic resource extraction were the growth in labour material intensity, biotic extraction productivi…