Search results for "P3"

showing 10 items of 786 documents

A new perspective on adolescent athletes’ transition into upper secondary school : A longitudinal mixed methods study protocol

2016

The challenge of combining elite sport and education into a dual career pathway remains to be a source of concern for many high-performance athletes. Previous research findings suggest that committed participation in both domains is highly demanding and success in one pursuit often comes at the expense of the other. There are emergent studies, however, that argue for the beneficial and complementary nature of dual career pathways. Consequently, we emphasize the importance of understanding the processes underlying differences in the development of athletes’ life trajectories. This article presents a study protocol to explore new methodological and analytical approaches that may extend curren…

mixed methodslcsh:BF1-990Identity (social science)050109 social psychologyCareer PathwaysDevelopmental psychology03 medical and health sciences0302 clinical medicinemotivation0501 psychology and cognitive sciencesSociocultural evolutionta315General Psychologyta515identitystudent athletesbiologyburnoutAthletes05 social sciencesPerspective (graphical)lcsh:QP351-495transition030229 sport sciencesDUAL (cognitive architecture)biology.organism_classificationlcsh:Psychologylcsh:Neurophysiology and neuropsychologycareer constructiondual careerPsychological well-beingElitepsychological well-beingPsychologySocial psychologyCogent Psychology
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Autobiografinen opettajatutkimus ottaa ja antaa

2016

Aikuiskasvatuksen tutkimusmenetelmiä: Aikuiskasvatuksen asiantuntijat esittelevät aikuiskasvatustieteen tutkimusmenetelmiä ja näkökulmia tutkimukseen

muistelmatmuistelmat [http://www.yso.fi/onto/yso/p8111]kokemuksetkokemukset [http://www.yso.fi/onto/yso/p3209]elämäkertatutkimus [http://www.yso.fi/onto/yso/p8110]General MedicineGeneral ChemistryelämäkertatutkimusopettajatPuheenvuorojaopettajat [http://www.yso.fi/onto/yso/p1117]Aikuiskasvatus
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Effect of Training-Induced Changes in Achilles Tendon Stiffness on Muscle–Tendon Behavior During Landing

2018

During rapid deceleration of the body, tendons buffer part of the elongation of the muscle–tendon unit (MTU), enabling safe energy dissipation via eccentric muscle contraction. Yet, the influence of changes in tendon stiffness within the physiological range upon these lengthening contractions is unknown. This study aimed to examine the effect of training-induced stiffening of the Achilles tendon on triceps surae muscle–tendon behavior during a landing task. Twenty-one male subjects were assigned to either a 10-week resistance-training program consisting of single-leg isometric plantarflexion (n = 11) or to a non-training control group (n = 10). Before and after the training period, plantarf…

musculoskeletal diseasesenergy dissipationtendon propertiesPhysiologyQP301.H75_Physiology._Sport.Strain (injury)Isometric exerciseKinematicslcsh:Physiologyjänteet03 medical and health sciencesEccentric muscle contractionstiffness0302 clinical medicinePhysiology (medical)jäykkyysmedicineenergy absorptionta315Original ResearchAchilles tendonlcsh:QP1-981business.industryUltrasoundmechanical buffer030229 sport sciencesFasciclemedicine.diseasemusculoskeletal systemTendonAchilles tendonmedicine.anatomical_structurevoimaharjoittelukantajännebusiness030217 neurology & neurosurgeryBiomedical engineering
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Comprehensive analysis of interacting proteins and genome-wide location studies of the Sas3-dependent NuA3 histone acetyltransferase complex

2014

Highlights • We characterise Sas3p and Gcn5p active HAT complexes in WT and deleted TAP-strains. • We confirm that Pdp3p interacts with NuA3, histones and chromatin regulators. • Pdp3p MS-analysis reveals its phosphorylation, ubiquitination and methylation. • Sas3p can substitute Gcn5p in acetylation of histone H3K14 but not of H3K9. • Genome-wide profiling of Sas3p supports its involvement in transcriptional elongation.

nt nucleotidePTM post-translational modificationNuA3 histone acetyltransferase complexChIP-on-chip chromatin immunoprecipitation with genome-wide location arraysBiologyArticleGeneral Biochemistry Genetics and Molecular BiologyChromatin remodelingHistonesHistone H3NuA3 nucleosomal acetyltransferase of histone H3Histone H1Histone H2APdp3TAP–MS strategyHistone codelcsh:QH301-705.5TAP tandem affinity purificationGeneticsRNAPII RNA polymerase IIHistone acetyltransferaseWCE whole cell extractSAGA Spt-Ada-Gcn acetyltransferaseWT wild-typeChromatinYeastCell biologyChIP-on-chiplcsh:Biology (General)Histone methyltransferasebiology.proteinHAT histone acetyltransferaseTSS transcription start siteFEBS Open Bio
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Utilidad de la onda P300 como marcador de fatiga cognitiva en médicos internos residentes tras una jornada laboral de 24 horas

2015

La onda P300 fue el primer potencial evocado cognitivo que se conoció, descrita en 1965 por Sutton et al. Se caracteriza por una gran onda positiva, máxima en línea media del cuero cabelludo, que aparece alrededor de 300 milisegundos después de un estímulo infrecuente y relevante para una tarea. Viene determinada por la latencia al pico máximo y por su amplitud, parámetros que pueden afectarse por la privación de sueño, como se ha visto en estudios previos. La afectación de las habilidades cognitivas que causan las guardias de 24 horas en los médicos internos residentes es un tema de interés por las implicaciones legales que tiene a la hora de regular las horas de trabajo de estos profesion…

onda P300potenciales evocados cognitivoshabilidades cognitivasUNESCO::CIENCIAS DE LA VIDA::Fisiología humana ::Neurofisiologíaprivación de sueñoMIR:CIENCIAS DE LA VIDA::Fisiología humana ::Neurofisiología [UNESCO]
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p38 MAPK in cadmium-treated MDA-MB231 breast cancer cells

2008

p38 MAPK cadmium breast cancer cellsSettore BIO/06 - Anatomia Comparata E Citologia
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Activation of the p38MAPK cascade is associated with upregulation of TNF alpha receptors in the spinal motor neurons of mouse models of familial ALS.

2005

Phosphorylated p38 mitogen-activated protein kinase (p38MAPK), but not activated c-jun-N-terminal kinase (JNK), increases in the motor neurons of transgenic mice overexpressing ALS-linked SOD1 mutants at different stages of the disease. This effect is associated with a selective increase of phosphorylated MKK3-6, MKK4 and ASK1 and a concomitant upregulation of the TNFalpha receptors (TNFR1 and TNFR2), but not IL1beta and Fas receptors. Activation of both p38 MAPK and JNK occurs in the activated microglial cells of SOD1 mutant mice at the advanced stage of the disease; however, this effect is not accompanied by the concomitant activation of the upstream kinases ASK1 and MKK3,4,6, while both …

p38 mitogen-activated protein kinasesMAP Kinase Kinase 3Mice TransgenicMAP Kinase Kinase 6BiologyMAP Kinase Kinase Kinase 5p38 Mitogen-Activated Protein KinasesReceptors Tumor Necrosis FactorCellular and Molecular NeuroscienceMiceSuperoxide Dismutase-1Downregulation and upregulationAnimalsHumansASK1RNA Messengerfas ReceptorPhosphorylationReceptorProtein kinase AMolecular BiologyP38MAPK cascadeMotor NeuronsKinaseSuperoxide DismutaseTumor Necrosis Factor-alphaAmyotrophic Lateral SclerosisJNK Mitogen-Activated Protein KinasesReceptors Interleukin-1Cell BiologyCell biologyEnzyme ActivationMice Inbred C57BLDisease Models AnimalTumor Necrosis Factor Decoy ReceptorsSpinal CordReceptors Tumor Necrosis Factor Type IDisease ProgressionTumor necrosis factor alphaSignal TransductionMolecular and cellular neurosciences
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Protein Phosphorylation by Peroxisome Proliferators: Species-specific Stimulation of Protein Kinases and Its Role in PP-induced Transcriptional Activ…

1996

p38 mitogen-activated protein kinasesMicrobodiesGene Expression Regulation EnzymologicGeneral Biochemistry Genetics and Molecular BiologyMAP2K7Retinoblastoma-like protein 1History and Philosophy of ScienceAnimalsHumansProtein phosphorylationClofibrateRNA MessengerAcetyl-CoA C-AcetyltransferaseProtein kinase ACells CulturedProtein Kinase CHypolipidemic AgentsbiologyChemistryKinaseGeneral NeuroscienceGRB10Autophagy-related protein 13PhosphoproteinsStaurosporineRats Inbred F344RatsCell biologybiology.proteinProtein KinasesAnnals of the New York Academy of Sciences
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Different kind of stress activate different isoforms of p38 MAPK in sea urchin embryos

2007

p38 MAPK stress
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Studies on the insecticidal mechanism of Bacillus thuringiensis Vip3A and Cry proteins

2022

El control de plagas y patógenos ha tenido un efecto importante en la mejora del rendimiento de los sistemas agrícolas a nivel mundial. Diferentes tipos de insecticidas químicos se han usado extensivamente durante mucho tiempo para el control de plagas de insectos. Debido a la aparición de resistencias, problemas de contaminación de aguas y problemas de salud humana causados por dichos insecticidas de síntesis, la agricultura moderna necesita una estrategia de gestión integrada de plagas más saludable, respetuosa con el medio ambiente y sostenible. El uso de Bacillus thuringiensis (Bt) y sus proteínas insecticidas para el control de plagas es una de las estrategias biotecnológicas más impor…

pest managementinsecticidal proteinsvip3 proteinsUNESCO::CIENCIAS DE LA VIDAbacillus thuringiensisBt:CIENCIAS DE LA VIDA [UNESCO]
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