Search results for "PAM"
showing 10 items of 1768 documents
Fractura social y ciudadana
2005
Advantage of rare infanticide strategies in an invasion experiment of behavioural polymorphism
2012
Killing conspecific infants (infanticide) is among the most puzzling phenomena in nature. Stable polymorphism in such behaviour could be maintained by negative frequency-dependent selection (benefit of rare types). However, it is currently unknown whether there is genetic polymorphism in infanticidal behaviour or whether infanticide may have any fitness advantages when rare. Here we show genetic polymorphism in non-parental infanticide. Our novel invasion experiment confirms negative frequency-dependent selection in wild bank vole populations, where resource benefits allow an infanticidal strategy to invade a population of non-infanticidal individuals. The results show that infanticidal beh…
Paradigm of tunable clustering using Binarization of Consensus Partition Matrices (Bi-CoPaM) for gene discovery
2013
Copyright @ 2013 Abu-Jamous et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Clustering analysis has a growing role in the study of co-expressed genes for gene discovery. Conventional binary and fuzzy clustering do not embrace the biological reality that some genes may be irrelevant for a problem and not be assigned to a cluster, while other genes may participate in several biological functions and should simultaneously belong to multiple clusters. Also, these algorithms cannot generate tight cluster…
The GABAergic effect of low doses of lorazepam on social behavior
2002
The aim of this work was to test the antiaggressive effects of lorazepam and to determine whether these effects were mediated by benzodiazepine receptors. In a first experiment, male mice were injected with lorazepam in a range of low doses (0.05, 0.1, 0.2, and 0.6 mg/kg) or saline solution. In a second experiment, 1 mg/kg of Ro 15-1788, a benzodiazepine receptor antagonist, and a saline solution were injected before the behavioral test. Results showed that 0.6 mg/kg of lorazepam was the only dose that decreased the total duration of threat ( P < .01) and social investigation ( P < .05) and that 1 mg/kg of Ro 15-1788 had no effects. In the third experiment, animals received two injec- tions…
G protein biased signaling by non-catechol dopamine D1 receptor agonists
2020
Dopamine is a catecholamine neurotransmitter with essential roles in voluntary movement, working memory, attention, and reward. Dopamine acts through five G protein coupled receptors with the D1 and D5 receptors (D1R) stimulating Galphas/olf activation and increasing neuronal excitability. Deficits in D1R signaling are implicated in Parkinson’s disease motor deficits as well as cognitive deficits in schizophrenia and attention deficit hyperactivity disorder. For more than 40 years, academic and industry scientists have been searching for a drug-like D1R agonist, but this has remained elusive. The challenge in developing D1R selective agonists is that all previous agonists possess a common p…
Pašvadīta koučinga ietekme uz darba pašefektivitāti
2018
Pētījuma “Pašvadīta koučinga ietekme uz darba pašefektivitāti” mērķis bija noskaidrot pašvadīta koučinga ietekmi uz darba pašefektivitāti un tās saistību ar pamata pašnovērtējumu un gatavību mainīties. Pētījumā pieteicās 176 dalībnieki, kuri randomizēti tika iedalīti eksperimentālā un kontroles grupā ar mērķi paaugstināt dalībnieku darba pašefektivitāti vai laimes izjūtu. Tika veikti divi darba pašefektivitātes, pamata pašnovērtējuma un gatavības mainīties mērījumi. Otro mērījumu veica 75 dalībnieki. Pētījuma rezultāti norāda, ka neatkarīgi no dalības grupā, četru nedēļu pašvadīta koučinga programma paaugstina darba pašefektivitāti un norāda uz pozitīvu saistību starp darba pašefektivitāti,…
El coaching com a estratègia psicològica: punts clau per a la seua correcta aplicació
2019
espanolEl coaching es un termino que esta desde hace unos anos muy presente en nuestra sociedad y que muchas veces se usa como sinonimo de desarrollo personal, y bajo este paraguas se amparan diversas «terapias» o «pseudoterapias » con diferentes efectos sobre las personas que se someten a ellas. Es necesario, para adecuada practica del coaching que este concepto este bien definido y todos los que intervienen en el asuman su verdadero papel para el maximo beneficio de todos, sabiendo ademas que es una metodologia de base psicologica que se puede aplicar en diversos ambitos y por distintos profesionales, atendiendo a las correctas condiciones de aplicacion. En este trabajo y con el principal…
La professió dels pares i l'autoconcepte, els valors i el raonament moral dels fills
2018
espanolEn el presente estudio se analiza la relacion entre la profesion del padre y/o la madre y el autoconcepto, los valores y el juicio moral de los adolescentes, ademas de una breve aproximacion teorica a los tres constructos psicologicos. La muestra se compone de 350 adolescentes escolarizados con una media de 14.8 anos de edad. Se han obtenido MANOVAs, los cuales estudiaban la relacion entre la profesion del padre y la madre, y las puntuaciones objeto de investigacion. Respecto a la variable profesion de los padres y su relacion con el autoconcepto, aparecen diferencias marginalmente significativas en los niveles de autocomportamiento fisico en funcion de la profesion de las madres que…
Populetum pamiricae ass. nova – an endemic forest association to Pamir in Tajikistan (Middle Asia)
2015
Abstract The floristic structure, distribution and habitat requirements of a forest syntaxon, Populetum pamiricae ass. nova is described. The potential range of the Populetum pamiricae association comprises the mountains of eastern Tajikistan (Pamir Alai Mts), Kashgaria in western China (Kunlun Shan Mts) and north-eastern Afghanistan (Hindu Kush Mts) in Middle Asia. The biotope of this community comprises of high mountain river valleys situated at elevations between 2,500 and 3,200 m above sea level. Phytocoenoses of the Populetum pamiricae association are characterized by the apparent domination in the tree layer of a diagnostic species, Populus pamirica. The tree stand has a mean cover ar…
Genetic polymorphism in dopamine receptor D4 is associated with early body condition in a large population of greater flamingos,Phoenicopterus roseus
2012
Body condition is an important determinant of fitness in many natural populations. However, as for many fitness traits, the underlying genes that regulate body condition remain elusive. The dopamine receptor D4 gene (DRD4) is a promising candidate as dopamine is known to play an important role in the regulation of food intake and the metabolism of both glucose and lipids in vertebrates. In this study, we take advantage of a large data set of greater flamingos, Phoenicopterus roseus, to test whether DRD4 polymorphism predicts early body condition (EBC) while controlling for whole-genome effects of inbreeding and outbreeding using microsatellite multilocus heterozygosity (MLH). We typed 670 o…