Search results for "PEO"

showing 10 items of 1745 documents

ASTHMA–COPD OVERLAP SYNDROME (ACOS): PREVALENZA, QUALITÀ DI VITA CORRELATA ALLO STATO DI SALUTE E IMPLICAZIONI PROGNOSTICHE DI UNA NUOVA ENTITÀ NOSOL…

COPD; asthma; chronic obstructive pulmonary disease; overlap syndrome; mortality; older people.COPDolder people.asthmaoverlap syndromemortalitychronic obstructive pulmonary disease
researchProduct

IL CREDITO AI CONSUMATORI

2016

CREDITO AI CONSUMATORISettore IUS/01 - Diritto PrivatoDIRITTO PRIVATO EUROPEOCONTRATTI BANCARICONTRATTI COLLEGATI
researchProduct

Europa en la Calle

2000

CallesBolsaPrecariedadEspeculaciónVidal-Beneyto JoséEspañaConferencia IntergubernamentalOtra EuropaEuropa ultraliberalEUROPAPublicaciones: Obra periodística: Columnas y artículos de opiniónThatcherPueblo europeoHabermasManifestacionesCIGSeattlePatrimonio democráticoEuropa socialAgencia social europeaPOLÍTICAConciencia de puebloHuelga europeaExclusiónDemócratasFronterasSOCIEDADConsejo de NizaSocialdemocracia europeaPatrimonio socialPlataforma Niza 2000NizaCinismo liberal
researchProduct

Association between dietary folate intake and serum insulin-like growth factor-1 levels in healthy old women

2013

Abstract Objective High serum levels of insulin-like growth factor-1 (IGF-1) seem to coincide with higher rates of some types of cancer and the risk of all-cause mortality in old people. Eating vegetables seems to reduce IGF-1 levels because they are rich in micronutrients such as vitamins. This study investigates the possible association between vitamin intake and IGF-1 levels in a representative group of healthy elderly women with Mediterranean dietary habits. Design This cross-sectional study included 124 healthy women with a mean age of 71.3 ± 4.2 years and a mean body mass index (BMI) of 27.37 ± 3.48 kg/m 2 attending a mild fitness program twice a week at public gyms in Padova. The mai…

CalorieMediterranean dietEndocrinology Diabetes and Metabolismmedicine.medical_treatmentPhysiologyRiboflavinDiet MediterraneanBody Mass IndexEatingFolic AcidEndocrinologyVitamin D and neurologyHumansMedicineFood scienceInsulin-Like Growth Factor IAgedAged 80 and overImmunoassaybusiness.industryVitamin EConfoundingMicronutrientCross-Sectional StudiesBody CompositionFemaleFolates IGF-1 Old people Mediterranean dietEnergy IntakebusinessBody mass indexBiomarkersGrowth Hormone & IGF Research
researchProduct

Europa-Santiago de Compostela

1985

Se trata de una nota de José Vidal-Beneyto para Marcelino Oreja sobre el Camino de Santiago (en el marco del Consejo de Europa).

Camino de SantiagoCulturaVidal-Beneyto JoséNotas y Memorandos: Consejo de EuropaItinerarios culturares europeosEuropaCompostelaConsejo de EuropaPolítica cultural
researchProduct

Biopiracy and the right to self-determination of indigenous peoples.

2018

Abstract Background: Since over thirty years, I work on the unclear legal situation of in which indigenous peoples find themselves today in the beginning mainly in the USA and later also in Canada, Australia and New Zealand. The status of indigenous people and native nations is characterized as a mixture of national and international law. Hypothesis/Purpose: To clarify the status of indigenous people it is necessary to analyze and interpret carefully hundreds of old treaties, international declarations and covenants, national statutes and jurisprudence, especially the old leading decisions of the US-Supreme Court. Such an analysis and interpretation should prove that indigenous people have …

CanadaUnited NationsPharmaceutical ScienceTheftIndigenousStatute03 medical and health sciences0302 clinical medicinePopulation GroupsPolitical scienceDrug DiscoveryComparative lawHumansTreaty030304 developmental biologyPharmacology0303 health sciencesAustraliaDeclaration on the Rights of Indigenous PeoplesBiodiversityInternational lawIndigenous rightsUnited StatesComplementary and alternative medicine030220 oncology & carcinogenesisLawPersonal AutonomyIndians North AmericanMolecular MedicineMinority rightsNew ZealandPhytomedicine : international journal of phytotherapy and phytopharmacology
researchProduct

X Chromosome Contribution to the Genetic Architecture of Primary Biliary Cholangitis

2021

Background & aims: Genome-wide association studies in primary biliary cholangitis (PBC) have failed to find X chromosome (chrX) variants associated with the disease. Here, we specifically explore the chrX contribution to PBC, a sexually dimorphic complex autoimmune disease. Methods: We performed a chrX-wide association study, including genotype data from 5 genome-wide association studies (from Italy, United Kingdom, Canada, China, and Japan; 5244 case patients and 11,875 control individuals). Results: Single-marker association analyses found approximately 100 loci displaying P < 5 × 10-4, with the most significant being a signal within the OTUD5 gene (rs3027490; P = 4.80 × 10-6; odds…

Canadian-US PBC Consortium0301 basic medicineMaleLinkage disequilibriumGenome-wide association studyDiseasePBCSettore MED/03 - GENETICA MEDICALinkage Disequilibrium0302 clinical medicineUK-PBC ConsortiumGenotypeMitochondrial Precursor Protein Import Complex ProteinsItalian PBC Genetics Study GroupOdds RatioX-Wide Association StudyJapan PBC-GWAS ConsortiumX chromosomeGeneticsLiver Cirrhosis BiliaryGastroenterologyForkhead Transcription FactorsDNA-Binding ProteinsShal Potassium Channels030211 gastroenterology & hepatologyFemaleAdultMonosaccharide Transport ProteinsSuperenhancerLocus (genetics)Single-nucleotide polymorphismBiologyProtein Serine-Threonine KinasesPolymorphism Single NucleotideArticleWhite People03 medical and health sciencesAsian PeopleProto-Oncogene ProteinsEndopeptidasesHumansCell LineageGenetic Predisposition to DiseaseMeta-analysiGenetic associationChromosomes Human XGastroenterology & HepatologyHepatology1103 Clinical SciencesMeta-analysis030104 developmental biologyGenetic Loci1114 Paediatrics and Reproductive MedicineMeta-analysis; Superenhancer; X-Wide Association Study1109 NeurosciencesCarrier ProteinsGenome-Wide Association Study
researchProduct

Comparison of Claudin 18.2 expression in primary tumors and lymph node metastases in Japanese patients with gastric adenocarcinoma.

2019

CLDN18.2 expression is highly prevalent in Japanese patients with gastric cancer, making it a targetable alteration, and supporting development of zolbetuximab as a therapeutic agent for this patient population.

Cancer Researchmedicine.medical_specialtymedicine.medical_treatmentPopulationprevalenceAdenocarcinomaGastroenterologyAsian PeopleStomach NeoplasmsInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineHumansRadiology Nuclear Medicine and imagingeducationLymph nodeIMAB362Chemotherapyeducation.field_of_studybiologybusiness.industrygastric cancerCancerAntibodies MonoclonalbiomarkersGeneral Medicinemedicine.diseaseImmunohistochemistryClaudinGene Expression Regulation Neoplasticmedicine.anatomical_structureOncologyLymphatic MetastasisClaudinsbiology.proteinImmunohistochemistryBiomarker (medicine)Original ArticleAntibodybusinessJapanese journal of clinical oncology
researchProduct

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

2013

Elevated serum urate concentrations can cause gout, a prevalent and painful inflammatory arthritis. By combining data from >140,000 individuals of European ancestry within the Global Urate Genetics Consortium (GUGC), we identified and replicated 28 genome-wide significant loci in association with serum urate concentrations (18 new regions in or near TRIM46, INHBB, SFMBT1, TMEM171, VEGFA, BAZ1B, PRKAG2, STC1, HNF4G, A1CF, ATXN2, UBE2Q2, IGF1R, NFAT5, MAF, HLF, ACVR1B-ACVRL1 and B3GNT4). Associations for many of the loci were of similar magnitude in individuals of non-European ancestry. We further characterized these loci for associations with gout, transcript expression and the fractional…

Candidate geneInhibins/geneticsGenome-wide association studyGENETIC-LOCIchemistry.chemical_compound0302 clinical medicineserum urateGene FrequencyGout/bloodassociation analysis serum urateGlucose/metabolismSettore MED/14 - NEFROLOGIAHyperuricemiaserum; urate; genePOPULATIONMETABOLIC SYNDROMEGenetics0303 health scienceseducation.field_of_studybiologyPolymorphism Single Nucleotide/genetics3. Good healthHYPERURICEMIAGenetic Loci/genetics/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSLC22A12Single Nucleotide/geneticsSNPsSignal TransductionMOLECULAR PHYSIOLOGYserum urate concentrations gout genome-wide meta-analysisEuropean Continental Ancestry GroupPopulationPolymorphism Single NucleotideWhite PeopleUric Acid/bloodserum urate concentrationsgenome-wide meta-analysis03 medical and health sciencesSDG 3 - Good Health and Well-beinguric acidGeneticsmedicineHumansInhibinsPolymorphismeducation030304 developmental biology030203 arthritis & rheumatologyAnalysis of VarianceGOUTIDENTIFICATIONTRANSPORTERCARDIOVASCULAR-DISEASE RISKta3121medicine.diseaseassociation analysisGoutmeta-analysisGlucosechemistryGenetic Locigenome-wide association studiesbiology.proteinSignal Transduction/geneticsUric acidURIC-ACID LEVELSGenome-Wide Association StudySLC2A9
researchProduct

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

2013

Author version made available in accordance with the publisher's policy.

Candidate geneRefractive errorBone Morphogenetic Protein 2Genome-wide association studyVARIANTSGenomeGenome-wide association studies0302 clinical medicineRisk FactorsMyopiaGRIA4Genetics0303 health sciencesKCNQ Potassium ChannelsDisease geneticsEYE GROWTHASSOCIATIONRETINAL-PIGMENT EPITHELIUMRefractive ErrorsGenetic load3. Good healthADAPTED MOUSE RETINAMeta-analysisACIDPOTASSIUM CHANNELEXPRESSIONSingle-nucleotide polymorphismBiologyWhite PeopleArticle03 medical and health sciencesAsian PeoplemedicineGeneticsHumansGenetic Predisposition to DiseaseReceptors AMPAgene; myopia; refractive030304 developmental biologyHomeodomain Proteinsta1184ta3121medicine.diseaseGENEAlcohol OxidoreductasesSERINE-PROTEASEbiology.protein030221 ophthalmology & optometrySusceptibility locusTrans-ActivatorsEye disorderLamininSerine ProteasesGWAS; meta-analyses; refractive error; myopiaGenome-Wide Association StudyNature Genetics
researchProduct