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High-frequency conductive hearing loss as a diagnostic test for incomplete ossicular discontinuity in non-cholesteatomatous chronic suppurative otiti…

2017

Chronic suppurative otitis media, with or without cholesteatoma, may lead to erosion of the ossicles and discontinuity of the ossicular chain. In incomplete ossicular discontinuity (IOD), partial erosion of the ossicles occurs, but some sound transmission is noted throughout the ossicular chain. High-frequency conductive hearing loss (HfCHL) has been considered a hallmark of incomplete ossicular discontinuity. This study aims to evaluate the use of HfCHL as a preoperative predictor of IOD in patients with non-cholesteatomatous chronic suppurative otitis media. The HfCHL test was defined as the preoperative air-bone gap (ABG) at 4 kHz minus the average of the ABG at 0.25 and 0.5 kHz. The tes…

MaleMedical DoctorsHealth Care ProvidersChronic Suppurative Otitis MediaHearing Loss Conductivelcsh:MedicineOtologyDeafnessOtitis Media Suppurative0302 clinical medicineMedicine and Health SciencesMedical PersonnelProspective Studieslcsh:Science030223 otorhinolaryngologyHearing DisordersEar OssiclesMultidisciplinarymedicine.diagnostic_testCholesteatomaAudiologyMiddle AgedConductive hearing lossProfessionsmedicine.anatomical_structureMiddle earAudiometry Pure-ToneFemaleRadiologymedicine.symptomAnatomyResearch ArticleAdultmedicine.medical_specialtySoft TissuesAdolescentHearing lossSurgical and Invasive Medical ProceduresSensitivity and Specificity03 medical and health sciencesYoung AdultDiagnostic MedicinePhysiciansmedicineotorhinolaryngologic diseasesHumansSurgeonsOssiclesbusiness.industrylcsh:RMiddle EarBiology and Life SciencesGold standard (test)medicine.diseaseHealth CareOtitis MediaBiological TissueOtorhinolaryngologyEarsPeople and Placeslcsh:QPopulation Groupingssense organsAudiometrybusinessHead030217 neurology & neurosurgeryPLoS ONE
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A smart tele-cytology point-of-care platform for oral cancer screening.

2019

Early detection of oral cancer necessitates a minimally invasive, tissue-specific diagnostic tool that facilitates screening/surveillance. Brush biopsy, though minimally invasive, demands skilled cyto-pathologist expertise. In this study, we explored the clinical utility/efficacy of a tele-cytology system in combination with Artificial Neural Network (ANN) based risk-stratification model for early detection of oral potentially malignant (OPML)/malignant lesion. A portable, automated tablet-based tele-cytology platform capable of digitization of cytology slides was evaluated for its efficacy in the detection of OPML/malignant lesions (n = 82) in comparison with conventional cytology and hist…

MaleMedical DoctorsHealth Care ProvidersPathology and Laboratory Medicine030218 nuclear medicine & medical imaging0302 clinical medicineCohen's kappaConventional cytologyCytologyImage Processing Computer-AssistedMedicine and Health SciencesMedical PersonnelEarly Detection of CancerMultidisciplinaryOral cancer screeningQRMiddle AgedTelemedicine3. Good healthProfessionsOncology030220 oncology & carcinogenesisMedicineFemaleMouth NeoplasmsRadiologyAnatomyRisk assessmentAlgorithmsResearch ArticleComputer and Information SciencesDysplasiamedicine.medical_specialtyHistologyCytodiagnosisPoint-of-Care SystemsRemote diagnosisScienceEarly detectionRisk AssessmentSensitivity and Specificity03 medical and health sciencesSigns and SymptomsDiagnostic MedicineArtificial IntelligenceCancer Detection and DiagnosismedicineHumansArtificial Neural NetworksPoint of careComputational Neurosciencebusiness.industryBiology and Life SciencesComputational BiologyCell BiologyPathologistsHealth CarePeople and PlacesLesionsPopulation GroupingsNeural Networks ComputerCytologybusinessNeurosciencePLoS ONE
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Risk factors for incidental durotomy during posterior open spine surgery for degenerative diseases in adults: A multicenter observational study.

2017

Incidental durotomy (ID) is a common intraoperative complication of spine surgery. It can lead to persistent cerebrospinal fluid leakage, which may cause serious complications, including severe headache, pseudomeningocele formation, nerve root entrapment, and intracranial hemorrhage. As a result, it contributes to higher healthcare costs and poor patient outcomes. The purpose of this study was to clarify the independent risk factors that can cause ID during posterior open spine surgery for degenerative diseases in adults. We conducted a prospective multicenter study of adult patients who underwent posterior open spine surgery for degenerative diseases at 10 participating hospitals from July…

MaleMedical DoctorsPhysiologymedicine.medical_treatmentHealth Care Providerslcsh:MedicinePathology and Laboratory MedicineDegenerative DiseasesBody Mass Index0302 clinical medicineMathematical and Statistical TechniquesEndocrinologyRisk FactorsMedicine and Health SciencesProspective StudiesMedical PersonnelProspective cohort studyIntraoperative Complicationslcsh:ScienceMusculoskeletal System030222 orthopedicsMultidisciplinaryLumbar VertebraeIncidence (epidemiology)Neurodegenerative DiseasesMiddle AgedPseudomeningoceleProfessionsmedicine.anatomical_structurePhysiological ParametersPhysical SciencesRegression AnalysisFemaleAnatomyStatistics (Mathematics)Research Articlemedicine.medical_specialtyIntraoperative ComplicationEndocrine DisordersSurgical and Invasive Medical ProceduresLumbar vertebraeResearch and Analysis Methods03 medical and health sciencesDiscectomyPhysiciansmedicineDiabetes MellitusHumansStatistical MethodsAgedSurgeonsbusiness.industryBody Weightlcsh:RBiology and Life SciencesHealth Risk AnalysisSpineSurgeryHealth CareMetabolic DisordersPeople and PlacesObservational studyPopulation Groupingslcsh:QDura MaterbusinessBody mass index030217 neurology & neurosurgeryMathematicsPLoS ONE
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Predictive Score Card in Lumbar Disc Herniation: Is It Reflective of Patient Surgical Success after Discectomy?

2016

Does the Finneson–Cooper score reflect the true value of predicting surgical success before discectomy? The aim of this study was to identify reliable predictors for surgical success two year after surgery for patients with LDH. Prospective analysis of 154 patients with LDH who underwent single-level lumbar discectomy was performed. Pre- and post-surgical success was assessed by the Oswestry Disability Index (ODI) over a 2-year period. The Finneson-Cooper score also was used for evaluation of the clinical results. Using the ODI, surgical success was defined as a 30% (or more) improvement on the ODI score from the baseline. The ODI was considered the gold standard in this study. Finally, the…

MaleMedical Doctorsgenetic structuresPsychometricsHealth Care Providersmedicine.medical_treatmentSocial Scienceslcsh:MedicinePathology and Laboratory MedicineSeverity of Illness IndexDiagnostic RadiologyDisability Evaluation0302 clinical medicineSurveys and QuestionnairesOutcome Assessment Health CareMedicine and Health SciencesPsychologyProspective Studies030212 general & internal medicinelcsh:ScienceProspective cohort studyMusculoskeletal SystemAged 80 and overLumbar VertebraeMultidisciplinaryRadiology and ImagingMiddle AgedResearch AssessmentPrognosisMagnetic Resonance ImagingOswestry Disability IndexProfessionsmedicine.anatomical_structurePreoperative PeriodFemaleAnatomyIntervertebral Disc DisplacementDiskectomyResearch ArticleAdultmedicine.medical_specialtyPsychometricsSystematic ReviewsImaging TechniquesLower Back PainPainSurgical and Invasive Medical ProceduresLumbar vertebraeResearch and Analysis Methods03 medical and health sciencesSigns and SymptomsDiagnostic MedicinePhysiciansDiscectomySeverity of illnessmedicineHumansAgedSurgeonsSurgical repairbusiness.industrylcsh:RGold standardReproducibility of ResultsBiology and Life SciencesSpineSurgeryHealth CareSurgical RepairPeople and PlacesPhysical therapyPopulation Groupingslcsh:Qbusiness030217 neurology & neurosurgeryPLOS ONE
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Quantitative assessment and localization of the hollowing of the temple after craniectomy and cranioplasty–The frontozygomatic shadow

2021

Background After cranioplasty, in many cases a not negligible soft tissue defect remains in the temporozygomatical area, also referred to as a hollowing defect of the temple. Objective To assess the precise localization and volume of the hollowing defect, to optimize future cranioplasties. Methods CT data of patients who received craniectomy and conventional CAD cranioplasty in our institution between 2012 and 2018 were analyzed. CT datasets prior to craniectomy and after cranioplasty were subtracted to quantify the volume and localization of the defect. Results Out of 91 patients, 21 had suitable datasets. Five cases had good cosmetic results with no defect visible, 16 patients had an app…

MaleMedical Implantsmedicine.medical_treatmentHealth Care ProvidersComputed tomographyNervous System ProceduresQuantitative assessmentMedicine and Health SciencesMedical PersonnelMusculoskeletal SystemMultidisciplinarymedicine.diagnostic_testQRSoft tissueMiddle AgedBuilt StructuresCranioplastyProfessionsmedicine.anatomical_structureTreatment OutcomeMedicineSuperior temporal lineEngineering and TechnologyFemaleAnatomyPlastic Surgery and Reconstructive TechniquesResearch ArticleBiotechnologyAdultmedicine.medical_specialtyDecompressive CraniectomyStructural EngineeringSoft TissuesScienceSurgical and Invasive Medical ProceduresBioengineeringTemporal MuscleZygomatic processTemporal muscleCranioplastyTime-to-TreatmentPhysiciansmedicineHumansSkeletonAgedRetrospective StudiesSurgeonsbusiness.industrySkullBiology and Life SciencesPlastic Surgery ProceduresSurgeryHealth CareSkullBiological TissuePeople and PlacesMedical Devices and EquipmentPopulation GroupingsbusinessTomography X-Ray ComputedHeadPLoS ONE
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Mediterranean diet and quality of life: Baseline cross-sectional analysis of the PREDIMED-PLUS trial

2018

We assessed if a 17-item score capturing adherence to a traditional Mediterranean diet (MedDiet) was associated with better health-related quality of life among older Spanish men and women with overweight or obesity harboring the metabolic syndrome. We analyzed baseline data from 6430 men and women (age 55-70 years) participating in the PREDIMED-Plus study. PREDIMED-Plus is a multi-centre randomized trial testing an energy-restricted MedDiet combined with promotion of physical activity and behavioral therapy for primary cardiovascular prevention compared to a MedDiet alone. Participants answered a 36-item questionnaire about health-related quality of life (HRQoL) and a 17-item questionnaire…

MaleMediterranean dietCross-sectional studyMetabolic disordersSocial Sciencescardiovascular-diseaselaw.invention613 - Higiene en general. Higiene i salut personalEndocrinology0302 clinical medicinepreventionPsychologyPublic and Occupational HealthMental health and psychiatryadherencelcsh:Sciencemediana edadvalidationancianodieta3. Good healthhealth-statusdepressionObesitatDietaEndocrine Disorders03 medical and health sciencesCuina mediterràniaDiabetes MellitusHumansobesidadAgedPhysical activitylcsh:RassociationBiology and Life Sciencesbenefitsmedicine.diseaseObesitymortalityBenefitsAgronomyHealth CareCross-Sectional Studiesphysical-activity questionnairelcsh:QMetabolic syndromeOlder peopleestudios transversalesGerontologycumplimiento del pacienteEmotionshumanoslcsh:Medicine030204 cardiovascular system & hematologyOverweightDiet MediterraneanDieta mediterràniaPersones gransClinical trialsQuality of lifeRandomized controlled triallawPlant ProductsMedicine and Health Sciences030212 general & internal medicine2. Zero hungerMetabolic SyndromeMultidisciplinarysobrepesotratamiento por actividad físicaAgricultureMiddle AgedPhysical-activity questionnaireHealth-statusExercise TherapyQualitat de vidaHypertensionFemalemedicine.symptomResearch ArticleMediterranean cookingMediterranean dietmedicineObesityMortalityNutritionbusiness.industryOverweightMental healthDietSpaincalidad de vidaQuality of LifePatient ComplianceVegetable oilsbusinessCrop ScienceAssaigs clínics
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Description of Lifestyle, Including Social Life, Diet and Physical Activity, of People ≥90 years Living in Ikaria, a Longevity Blue Zone

2021

A cross-sectional observational study was conducted to describe the lifestyle of people ≥90 years, living in Evdilos or Raches, two municipalities of the Greek island of Ikaria, classified a longevity blue zone. The 71 participants were interviewed and underwent the Mediterranean Islands study food frequency questionnaire (MEDIS-FFQ) and the international physical activity questionnaire (IPAQ). The frequency of social contacts was daily for 77.9% of participants, weekly for 16.1%, and monthly for 5.9%. Most participants (90.0%) believed in God, and 81.4% took part in religious events. A total of 62.0% attended Panigiria festivals. Access to primary health care was considered difficult in th…

MaleMediterranean dietHealth Toxicology and Mutagenesismedia_common.quotation_subjectPhysical activityoldest old aged people030204 cardiovascular system & hematologyDiet MediterraneanArticleSocial life03 medical and health sciences0302 clinical medicinelongevityMedicineHumans030212 general & internal medicineExerciseLife Stylemedia_commonAgedAged 80 and overbusiness.industryPublic Health Environmental and Occupational HealthLongevityRSolidaritySocial relationIkariaCross-Sectional StudiesMedicineObservational studyFemaleMediterranean Islandsbusinesshealthy ageingDemographyInternational Journal of Environmental Research and Public Health
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Adherence to the Mediterranean Lifestyle and Desired Body Weight Loss in a Mediterranean Adult Population with Overweight: A PREDIMED-Plus Study

2020

Background. Body weight dissatisfaction is a hindrance to following a healthy lifestyle and it has been associated with weight concerns. Objectives. The aim of this study was to assess the association between the adherence to the Mediterranean lifestyle (diet and exercise) and the desired body weight loss in an adult Mediterranean population with overweight. Methods. Cross-sectional analysis in 6355 participants (3268 men; 3087 women) with metabolic syndrome and BMI (Body mass index) between 27.0 and 40.0 kg/m2 (55–75 years old) from the PREDIMED-Plus trial. Desired weight loss was the percentage of weight that participants wished to lose. It was categorized into four cut-offs of this perce…

MaleMediterranean dietObesidadejercicio físicoBody Mass Index:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]0302 clinical medicineSurveys and QuestionnairesAntineoplastic Combined Chemotherapy ProtocolsMedicinemediana edadeducation.field_of_studyanciano:Health Care::Health Care Quality Access and Evaluation::Quality of Health Care::Epidemiologic Factors::Age Factors [Medical Subject Headings]dietaprotocolos de quimioterapia antineoplásica combinada3. Good healthOlder adultsmetotrexatoprogramas de reducción de pesoObesitatlcsh:Nutrition. Foods and food supplyPersonas mayores frágilesIdeal weightLifestyles:Check Tags::Male [Medical Subject Headings]lcsh:TX341-641ArticleEstilo de vida03 medical and health sciences:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Overweight [Medical Subject Headings]:Anthropology Education Sociology and Social Phenomena::Human Activities::Exercise [Medical Subject Headings]ifosfamidaHumanscisplatinoIfosfamideeducationExerciseAgedconducta alimentaria:Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Metabolic Syndrome X [Medical Subject Headings]:Persons::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Psychology Social::Life Style [Medical Subject Headings]PREDIMED-Plusmedicine.diseaseObesityMethotrexate:Check Tags::Female [Medical Subject Headings]Desired weight lossMetabolic syndromeCisplatinBody mass indexDemographyobesitycumplimiento del pacientehumanos:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Mass Index [Medical Subject Headings]Ideal Body Weightdesired weight loss:Health Care::Health Care Facilities Manpower and Services::Health Promotion::Weight Reduction Programs [Medical Subject Headings]OverweightDiet MediterraneanMediterranean lifestyle:Health Care::Health Care Facilities Manpower and Services::Health Services::Preventive Health Services::Health Promotion::Healthy People Programs [Medical Subject Headings]Weight loss030212 general & internal medicine:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Health Behavior::Patient Compliance [Medical Subject Headings]Abdominal obesityolder adults:Persons::Persons::Age Groups::Adult::Aged [Medical Subject Headings]2. Zero hungerNutrition and Dieteticsmediterranean lifestylesobrepeso:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Nutrition Therapy::Diet Therapy::Diet Mediterranean [Medical Subject Headings]Age Factorsideal weightMiddle AgedPeso corporal ideal:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Ideal Body Weight [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies [Medical Subject Headings]Weight Reduction ProgramsBody imageFemalemedicine.symptompeso corporal idealEstils de vidadoxorrubicinabody imagePopulationImagen corporal030209 endocrinology & metabolism:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Feeding Behavior [Medical Subject Headings]overweightHealthy LifestyleObesity:Geographical Locations::Geographic Locations::Europe::Spain [Medical Subject Headings]business.industryíndice de masa corporalFeeding BehaviorOverweightDieta mediterráneaDietDoxorubicinSobrepesoPatient Compliance:Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Perception::Body Image [Medical Subject Headings]businessFood Science
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Associations between mental and oral health in Spain: a cross-sectional study of more than 23,000 people aged 15 years and over.

2020

Background:\ud \ud This study aimed to investigate associations between mental health and several parameters of oral health, controlling for a variety of important covariates, in a large representative sample of Spanish people.\ud \ud Methods:\ud \ud Data from the Spanish National Health Survey 2017 were analysed. Mental (i.e., depression, chronic anxiety, other psychiatric disorders) and oral health (i.e., dental caries, dental extraction, dental filling, gingival bleeding, tooth movement, dental material, missing tooth) were evaluated. Control variables included sex, age, marital status, education, smoking, alcohol consumption, and physical multimorbidity. Associations between psychiatric…

MaleMental health oral health marital status cross-sectional study SpainAdolescentCross-sectional studyPopulationmacromolecular substancesDental CariesRate ratio03 medical and health sciencessymbols.namesake0302 clinical medicineHumansMedicinecross-sectional studyMental health Spain cross-sectional study marital status oral health030212 general & internal medicinePoisson regressiona cross-sectional study of more than 23000 people aged 15 years and over- JOURNAL OF AFFECTIVE DISORDERS cilt.274 ss.67-72 2020 [Jacob L. Lopez-Sanchez G. F. Carvalho A. F. Shin J. I. Oh H. Yang L. Veronese N. SOYSAL P. Grabovac I. Koyanagi A. et al. -Paper Associations between mental and oral health in Spain]educationDepression (differential diagnoses)education.field_of_studybusiness.industry030206 dentistryMiddle AgedMental healthConfidence interval3. Good healthPsychiatry and Mental healthClinical Psychologystomatognathic diseasesCross-Sectional StudiesSpain[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental healthsymbolsMarital statusoral healthFemaleMental healthbusinessDemographymarital status
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Muscle-Related Polymorphisms (MSTN rs1805086 and ACTN3 rs1815739) Are Not Associated with Exceptional Longevity in Japanese Centenarians

2016

Myostatin (MSTN) and α-actinin-3 (ACTN3) genes are potentially associated with preservation of muscle mass and oxidative capacity, respectively. To explore the possible role of these genes in exceptional longevity (EL), the allele/genotype frequency distribution of two polymorphisms in MSTN (rs1805086, K153R) and ACTN3 (rs1815739, R577X) was studied in Japanese centenarians of both sexes (n = 742) and healthy controls (n = 814). The rs1805086 R-allele (theoretically associated with muscle mass preservation at the expense of oxidative capacity) was virtually absent in the two groups, where genotype distributions were virtually identical. Likewise, no differences in allele (p = 0.838 (women);…

MaleMetabolic Processes0301 basic medicineAgingHeredityPhysiologyAging and Cancerlcsh:MedicinePolimorfismo genéticoGenética humanaBiochemistry0302 clinical medicineGene FrequencyJapanPolymorphism (computer science)GenotypeMedicine and Health SciencesMorphogenesisActininlcsh:ScienceMusculoskeletal SystemProtein Metabolismmedia_commonGeneticseducation.field_of_studyMultidisciplinaryMusclesCancer Risk FactorsLongevityMuscle DifferentiationGenetic MappingOncologyPopulation SurveillanceFemaleAnatomyResearch ArticleAsian Continental Ancestry Groupmedicine.medical_specialtyGenotypemedia_common.quotation_subjectLongevityAncianoPopulationMuscle TissueVariant GenotypesBiology03 medical and health sciencesAsian PeopleInternal medicineGeneticsmedicineHumansAlleleeducationAllele frequencyAllelesGenetic Association StudiesPolymorphism Geneticlcsh:RBiology and Life SciencesMyostatinGenotype frequencyBiological TissueMetabolism030104 developmental biologyEndocrinologySkeletal MusclesLongevidadlcsh:QPhysiological ProcessesXX GenotypeOrganism Development030217 neurology & neurosurgeryDevelopmental BiologyPLOS ONE
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