Search results for "PES"
showing 10 items of 5212 documents
Nitrogen isotope evidence for stepwise oxygenation of the ocean during the Great Oxidation Event
2019
24 pages; International audience; The Earth’s oxygenation represents one of the most important environmental drivers of life’s evolution, with the first rise, known as ‘the Great Oxidation Event’ (GOE), corresponding to unpreceded accumulation of atmospheric O2, changes in the flux of marine nutrients and possibly global glaciations. However, the detailed evolution of the GOE is still debated, as for instance the accumulation trends of oceanic versus atmospheric oxygen and the nature of biogeochemical responses to oxygenation. Here, we combine organic carbon and bulk nitrogen isotope compositions with major element concentrations and iron speciation data of sedimentary rocks recovered from …
Understanding the fluctuations of perceived authenticity in cultural tourism : an investigation of Bali and Alsace contexts
2022
The marketing of cultural tourism faces a dilemma between maximizing the economic return and nurturing the culture’s social functions. It needs to attract segments driven by cultural motifs, through a differentiation based on authenticity. Perceived authenticity changes over a time, but how it does remains elusive to researchers. This research investigated fluctuations of existential authenticity in cultural tourists in Bali. Participants were purposively and conveniently-sampled among visitors of cultural attractions. It comprised two stages: qualitative for building the model, and quantitative fortesting the variables. The first employed Grounded Theory interviewing 24 visitors, found the…
Trace element systematics of tourmaline in pegmatitic and hydrothermal systems from the Variscan Schwarzwald (Germany): The importance of major eleme…
2013
article An extensive data set on the compositional variation of tourmaline from granitic pegmatites, from migmatitic gneisses and from various types of hydrothermal veins from the Schwarzwald, Germany, is provided. The investigated tourmalines are members of the alkali and X-vacant groups representing mostly dravite- schorl solid solutions with some analyses belonging to the foitite-Mg-foitite series. Oxygen isotope data on quartz-tourmaline pairs indicate formation temperatures between 550 and 350 °C for most of the quartz-tourmaline veins. Most of the tourmalines show strong sector zonation, fractionating certain major (e.g., Na, Mg), minor (e.g., Ti, Ca) and trace elements (e.g., Sr, Pb,…
Surveillance of pesticide residues in fruits from Valencia during twenty months (2004/05)
2010
Abstract The aim of this study was to investigate the pesticide residues in market fruits (oranges, tangerines, nectarines, peaches and khakis) from one Valencian Cooperative (Spain) and to conduct a monitoring of 32 organophosphorous, organonitrogen and organohalogenated pesticides and nine dithiocarbamate fungicides (DTCFs) usually applied on cultures of this area. Extracts were obtained by an official procedure for routine analysis based on ethyl acetate extraction. Residues of pesticides were determined by gas chromatography with nitrogen phosphorous detector (NPD), electron-capture detector (ECD) and mass spectrometry (MS) detectors. Mean recoveries obtained at fortification levels bet…
RESUME:Studies on the Chemical Control of Aonidiella aurantii (Mask.)
1974
Aonidiella aurantii (Mask.) which was accidentally introduced in Sicily in 1968 has since become a dangerous pest requesting special treatments in citrus groves. Experiments have been carried out on Citrus lemon to evaluate the efficacy of several organophosphorous compounds partly in mixture with white oil and this latter applied sole (cf. table 1). The results obtained against young females are set out in table 2; they show excellent results with almost all compounds whereas the same pesticides had a rather poor effect on mature females (cf. table 3). It is concluded that the replacement of white oils by organophosphorous compounds is not justified providing that the control is directed a…
Blood Component Therapy and Coagulopathy in Trauma: A Systematic Review of the Literature from the Trauma Update Group
2016
Background Traumatic coagulopathy is thought to increase mortality and its treatment to reduce preventable deaths. However, there is still uncertainty in this field, and available literature results may have been overestimated. Methods We searched the MEDLINE database using the PubMed platform. We formulated four queries investigating the prognostic weight of traumatic coagulopathy defined according to conventional laboratory testing, and the effectiveness in reducing mortality of three different treatments aimed at contrasting coagulopathy (high fresh frozen plasma/packed red blood cells ratios, fibrinogen, and tranexamic acid administration). Randomized controlled trials were selected alo…
Immune Evasion Proteins Enhance Cytomegalovirus Latency in the Lungs
2009
ABSTRACT CD8 T cells control cytomegalovirus (CMV) infection in bone marrow transplantation recipients and persist in latently infected lungs as effector memory cells for continuous sensing of reactivated viral gene expression. Here we have addressed the question of whether viral immunoevasins, glycoproteins that specifically interfere with antigen presentation to CD8 T cells, have an impact on viral latency in the murine model. The data show that deletion of immunoevasin genes in murine CMV accelerates the clearance of productive infection during hematopoietic reconstitution and leads to a reduced latent viral genome load, reduced latency-associated viral transcription, and a lower inciden…
Rapid nucleus-scale reorganization of chromatin in neurons enables transcriptional adaptation for memory consolidation
2020
AbstractThe interphase nucleus is functionally organized in active and repressed territories defining the transcriptional status of the cell. However, it remains poorly understood how the nuclear architecture of neurons adapts in response to behaviorally relevant stimuli that trigger fast alterations in gene expression patterns. Imaging of fluorescently tagged nucleosomes revealed that pharmacological manipulation of neuronal activity in vitro and auditory cued fear conditioning in vivo induce nucleus-scale restructuring of chromatin within minutes. Furthermore, the acquisition of auditory fear memory is impaired after infusion of a drug into auditory cortex which blocks chromatin reorganiz…
CD8 T Cells Control Cytomegalovirus Latency by Epitope-Specific Sensing of Transcriptional Reactivation
2006
ABSTRACT During murine cytomegalovirus (mCMV) latency in the lungs, most of the viral genomes are transcriptionally silent at the major immediate-early locus, but rare and stochastic episodes of desilencing lead to the expression of IE1 transcripts. This low-frequency but perpetual expression is accompanied by an activation of lung-resident effector-memory CD8 T cells specific for the antigenic peptide 168-YPHFMPTNL-176, which is derivedfrom the IE1 protein. These molecular and immunological findings were combined in the “silencing/desilencing and immune sensing hypothesis” of cytomegalovirus latency and reactivation. This hypothesis proposes that IE1 gene expression proceeds to cell surfac…
‘My Language! Heavens!’: Strange Tongues and the Denial of Mimesis in The Tempest
2008
The Tempest est la dernière pièce « italienne » de Shakespeare. Cet article se penche sur quelques unes des conséquences poétiques et métaphysiques de la convention qui consiste à faire correspondre l’anglais de la pièce à l’italien que sont sensés parler les personnages. Nous montrerons que cette convention est un paramètre essentiel de l’action dramatique et qu’elle contribue à la mise en évidence du caractère fondamentalement « Autre » de la langue du théâtre. Dans The Tempest, l’imbrication d’une langue inconnue et d’une langue familière débouche par métonymie et par métaphore sur un déni du principe classique de mimesis.