Search results for "PG"
showing 10 items of 1521 documents
Predicting adverse obstetric outcome after early pregnancy events and complications: a review.
2009
BACKGROUND The aim was to evaluate the impact of early pregnancy events and complications as predictors of adverse obstetric outcome. METHODS We conducted a literature review on the impact of first trimester complications in previous and index pregnancies using Medline and Cochrane databases covering the period 1980-2008. RESULTS Clinically relevant associations of adverse outcome in the subsequent pregnancy with an odds ratio (OR) > 2.0 after complications in a previous pregnancy are the risk of perinatal death after a single previous miscarriage, the risk of very preterm delivery (VPTD) after two or more miscarriages, the risk of placenta praevia, premature preterm rupture of membranes, V…
Hyperoxemia caused by resuscitation with pure oxygen may alter intracellular redox status by increasing oxidized glutathione in asphyxiated newly bor…
2002
In a prospective, randomized, blinded trial we have studied the effects of resuscitation upon oxygenation in a group of asphyxiated newly born infants receiving room air or 100% oxygen as the gas source. During the acute phase of asphyxia and until the resuscitation procedure concluded, we determined serial blood gases as well as reduced and oxidized glutathione, enzymes involved in the glutathione redox cycle, and antioxidant enzyme activities. The use of 100% oxygen caused a remarkable increase of partial pressures of oxygen in arterial blood, with values that were frequently above physiological levels (>100 mm Hg). In addition, we have found a significant correlation between hyperoxemia …
PGC-1 isoforms and their target genes are expressed differently in human skeletal muscle following resistance and endurance exercise
2015
The primary aim of the present study was to investigate the acute gene expression responses of PGC-1 isoforms and PGC-1a target genes related to mitochondrial biogenesis (cytochrome C), angiogenesis (VEGF-A), and muscle hypertrophy (myostatin), after a resistance or endurance exercise bout. In addition, the study aimed to elucidate whether the expression changes of studied transcripts were linked to phosphorylation of AMPK and MAPK p38. Nineteen physically active men were divided into resistance exercise (RE, n = 11) and endurance exercise (EE, n = 8) groups. RE group performed leg press exercise (10 9 10 RM, 50 min) and EE walked on a treadmill (~80% HRmax, 50 min). Muscle biopsies were ob…
CpG-Loaded Multifunctional Cationic Nanohydrogel Particles as Self-Adjuvanting Glycopeptide Antitumor Vaccines
2014
Self-adjuvanting antitumor vaccines by multifunctional cationic nanohydrogels loaded with CpG. A conjugate consisting of tumor-associated MUC1-glycopeptide B-cell epitope and tetanus toxin T-cell epitope P2 is linked to cationic nanogels. Oligonucleotide CpG complexation enhances toll-like receptor (TLR) stimulated T-cell proliferation and rapid immune activation. This co-delivery promotes induction of specific MUC1-antibodies binding to human breast tumor cells without external adjuvant.
Temata “Medijpratība” apguve sociālās zinībās 8.klasē
2019
Diplomdarba tema ir temata “Medijpratība” apguve sociālās zinībās 8.klasē. Darba autore izvēlējas šo tēmu, lai aktualizētu medijpratības apguves nepieciešamību sociālās zinības mācību stundās nepieciešamību. Kā pētījuma mērķi darba autore izvirzīja šādu hipotezi - sniegt izpratni par medijpratību, attīstīt prasmes mācību procesā, zināšanas un attieksmes mediju un citas informācijas lietošanā un publiskošanā. Darba uzdevumi bija veikt izpēti par medijpratību un iespējas to attīstīt, veikt pētījumu par 8. klases skolēnu zinašanam, apkopot un analizēt pētījuma rezultatus un veikt pārbaudes testēšanu, lai noskaidrot skolēnu zināšanas par medijpratību pēc temata “Medijpratība” sociālās zinības m…
Melodic structure and inner self in clinical improvisation
2016
This study investigates the analogies between the melodic evolution within clinical improvisation and the shifts in the core self, across the continuum of music therapy process. This investigation is facilitated by a hypothesis; that musical shifts in improvisation’s structure precede psychological shifts in improviser’s self during therapy. Melodic improvisations created within the Integrative Improvisational Music Therapy (IIMT) model (Erkkilä, 2016) are investigated as proposed in the Therapeutic Narrative Analysis (Aldridge & Aldridge, 2008): certain melodic episodes from significant improvisations are analyzed with the Repertory Grid Method (Kelly, 1995) and patterns of the musical dat…
“Throwing into the Whirlwind Vortex”: Unaccounted Memoirs about Blok by S. Korenev
2021
The article examines certain plots of the “Blok theme” in the 1920s Riga periodicals, which had not previously attracted the attention of researchers. The Russian press of independent Latvia (1919 –1940) has preserved many tens, if not hundreds, of articles, correspondences, documents, poetic texts dedicated to A.A. Blok’s personality and works. Among them are memoirs of people who were familiar with the poet, met with him, listened to his speeches. However, most of these scattered memoirs remain forgotten and are not taken into account in the Blok studies. The author recalls the texts of V.V. Tretyakov, A.M. Perfiliev and republishes from the Riga newspaper “Slovo” a memorial article about…
Kā veidot tūrisma pakalpojumus pieejamākus cilvēkiem ar mentāliem apgrūtinājumiem? Rokasgrāmata
2022
Grāmatas nolūks ir būt par pavadoni centienos padarīt tūrisma pakalpojumus pieejamākus cilvēkiem ar mentāliem apgrūtinājumiem un/vai invaliditāti. Šī grāmata var būt noderīga, ja pārstāvat: 1) tūrisma pakalpojumu sniedzēju; 2) tūrisma organizāciju; 3) politikas veidotājus; 4) biedrību personām ar mentāliem apgrūtinājumiem un/vai invaliditāti; 5) plašāku sabiedrību, kas ir ieinteresēta uzlabot tūrisma pakalpojumus cilvēkiem ar mentāliem apgrūtinājumiem un/vai invaliditāti. Šīs rokasgrāmatas saturs tapa, par pamatu ņemot šādi iegūtus datus: datus no sekundāriem avotiem un zinātniskās literatūras, no aptaujām un intervijām ar vairākām NVO, no sarunām ar ekspertiem tūrisma un psihiatriskas inva…
Amplicon-based high-throughput pooled sequencing identifies mutations in CYP7B1 and SPG7 in sporadic spastic paraplegia patients
2011
Hereditary spastic paraplegia (HSP) is a neurodegenerative disorder defined clinically by progressive lower limb spasticity and weakness. HSP is a genetically highly heterogeneous condition with at least 46 gene loci identified so far, involving X-linked, autosomal recessive (AR) and autosomal dominant inheritance. For correct diagnosis, molecular testing is essential because clinical parameters by themselves are not reliable to differentiate HSP forms. The purpose of this study was to establish amplicon-based high-throughput genotyping for AR-HSP. A sample of 187 index cases with apparently sporadic or recessive spastic paraplegia were analyzed by applying an array-based amplification stra…
Automašīnas gaismas ietekme uz redzes asumu miopijas gadījumā mezopiskos gaismas apstākļos
2018
Maģistra darbs rakstīts latviešu valodā uz 28 lapām, satur 18 attēlus un 84 atsauces uz literatūras avotiem. Darba mērķis: izpētīt, kā mainās redzes asums fotopiskos apstākļos salīdzinot ar mezopiskiem apstākļiem un apstākļos, kad uz dalībnieku tiek izstarota automašīnas luktura gaisma. Metode: uzdevumā redzes asums tika noteikts FrACT programmā uz datora ekrāna. Tests sastāv no baltiem Landolta gredzena optotipiem uz melna fona. Redzes asums tika salīdzināts fotopiskos, mezopiskos un no automašīnas luktura izstarotā ksenona un halogēnās spuldzes apgaismojuma apstākļos. Secinājumi: Mezopiskos apstākļos redzes asums ir zemāks nekā fotopiskos apstākļos. Halogēnas gaismas ietekme uz redzes asu…