Search results for "PHENOLS"

showing 10 items of 766 documents

Bioaccessibility of bioactive compounds after non-thermal processing of an exotic fruit juice blend sweetened with Stevia rebaudiana

2017

Abstract A comparative study of the bioaccessibility of bioactive compounds and antioxidant capacity in a fruit juice-Stevia rebaudiana mixture processed by pulsed electric fields (PEF), high voltage electrical discharges (HVED) and ultrasound (USN) technology at two equivalent energy inputs (32–256 kJ/kg) was made using an in vitro model. Ascorbic acid was not detected following intestinal digestion, while HVED, PEF and USN treatments increased total carotenoid bioaccessibility. HVED at an energy input of 32 kJ/kg improved bioaccessibility of phenolic compounds (34.2%), anthocyanins (31.0%) and antioxidant capacity (35.8%, 29.1%, 31.9%, for TEAC, ORAC and DPPH assay, respectively) compared…

DPPHBiological AvailabilityAscorbic AcidHealth benefitsAntioxidantsAnalytical ChemistryIn vitro modelAnthocyaninschemistry.chemical_compound0404 agricultural biotechnologyElectricityPhenolsSteviaUltrasonicsFood scienceCarotenoidchemistry.chemical_classification04 agricultural and veterinary sciencesGeneral MedicineIntestinal digestionAscorbic acidCarotenoids040401 food scienceFruit and Vegetable JuicesStevia rebaudianachemistrySweetening AgentsFruit juiceFood AnalysisFood ScienceFood Chemistry
researchProduct

Polish Yellow Sweet Clover (Melilotus officinalis L.) Honey, Chromatographic Fingerprints, and Chemical Markers

2017

A case study of Polish Melilotus officinalis honey was presented for the first time. Gas chromatography–mass spectrometry (GC-MS) (after steam distillation, Soxhlet extraction, ultrasonic solvent extraction, and solid phase extraction (SPE)) and targeted high performance liquid chromatography with a photodiode array detector (HPLC-PAD) were applied to determine the characteristic components of honey. While ubiquitous in most honeys, carbohydrates, terpene derivatives, and phenylacetic acid dominated in the Soxhlet extracts (25.54%) and in the application of SPE (13.04%). In addition, lumichrome (1.85%) was found, and may be considered as a marker of this honey. Due to the presence of these …

DPPHFlavonoidPharmaceutical Science01 natural sciencesHigh-performance liquid chromatographyvolatileAntioxidantsCatechinGas Chromatography-Mass SpectrometryArticleAnalytical Chemistrylaw.inventionlcsh:QD241-441Steam distillationchemistry.chemical_compound0404 agricultural biotechnologyPhenolslcsh:Organic chemistryMelilotus officinalislawGallic AcidDrug DiscoveryMedicagoHumansGallic acidSolid phase extractionPhysical and Theoretical ChemistryChromatography High Pressure LiquidFlavonoidschemistry.chemical_classificationChromatographybiology010401 analytical chemistryOrganic ChemistryExtraction (chemistry)honey markersHoney04 agricultural and veterinary sciencesbiology.organism_classificationMelilotus officinalis040401 food science0104 chemical sciencesyellow sweet cloverchemistryChemistry (miscellaneous)yellow sweet clover; <i>Melilotus officinalis</i>; phenolic; volatile; honey markersMolecular MedicinephenolicMolecules; Volume 22; Issue 1; Pages: 138
researchProduct

Phytochemical profile and bioactivity of traditional ayurvedic decoctions and hydro-alcoholic macerations of Boerhaavia diffusa L. and Curculigo orch…

2015

Decoctions (DECs) and hydro-alcoholic extracts (HEs) prepared from roots of Boerhaavia diffusa L. (Nyctaginaceae) and Curculigo orchioides Gaertn. (Hypoxidaceae) were phytochemically characterised by HPLC-DAD and profiled for their antioxidant, antigenotoxic and cytotoxic activities. B. diffusa DEC was rich in ferulic acid and vanillin, while the HE also contained boeravinone B and eupalitin. Both C. orchioides HE and DEC displayed the main occurrence of orcinol-β-d-glucoside and curculigoside A. Antioxidant activity was assayed through spectrophotometric DPPH, ABTS and β-carotene bleaching test, and using (HP)TLC bioautographic strategies. For both crude drugs, HE was the best performing p…

DPPHPhytochemicalsantioxidant activityDecoctionPlant ScienceBiochemistryPlant RootsAntioxidantsAnalytical ChemistryNOchemical fingerprintingFerulic acidchemistry.chemical_compoundCurculigoPhenolsEupalitinCell Line TumorOrganic chemistryHumansCurculigosideBoerhaavia diffusa; Curculigo orchioides; traditional preparations; chemical fingerprinting; antioxidant activity; genotoxicity; cytotoxicitytraditional preparationsbiologyTraditional medicinePlant ExtractsCurculigo orchioidesOrganic Chemistrygenotoxicitybiology.organism_classificationAntineoplastic Agents PhytogenicCurculigo orchioidesMedicine AyurvedicHypoxidaceaeBoerhaavia diffusachemistrycytotoxicityChemical fingerprintingNyctaginaceae
researchProduct

Traditionally used Thai medicinal plants: in vitro anti-inflammatory, anticancer and antioxidant activities.

2009

In order to assess traditional Thai claims about the therapeutic potential of medicinal plants and to select plants for future phytochemical research, nine plant species with anti-inflammatory uses were selected from Thai textbooks and assessed for their in vitro anti-inflammatory, antiproliferative and antioxidant activities.Nuclear factor-kappaB (NF-kappaB) inhibitory effects in stably transfected HeLa cells were determined by luciferase assay, and effects on LPS-induced pro-inflammatory mediators prostaglandin E2 (PGE2), interleukin (IL)-6, IL-1beta, and tumour necrosis factor (TNF)alpha in primary monocytes were assessed by ELISA. Cytotoxic activities were examined against HeLa cells, h…

DPPHmedicine.drug_classCell SurvivalInterleukin-1betaAnti-Inflammatory AgentsPharmacognosyAsteraceaeTransfectionAnti-inflammatoryAntioxidantsDinoprostoneMonocytesHeLachemistry.chemical_compoundInhibitory Concentration 50MagnoliopsidaPhenolsDrug DiscoveryMedicineHumansGynuraPharmacologyPlants MedicinalTraditional medicinebiologyDose-Response Relationship Drugbusiness.industryInterleukin-6Plant ExtractsTumor Necrosis Factor-alphaNF-kappa Bbiology.organism_classificationThailandOroxylum indicumAntineoplastic Agents PhytogenicPolygonaceaeRhinacanthus nasutusPhytochemicalchemistryDrug Resistance NeoplasmBignoniaceaeLipid PeroxidationMedicine TraditionalInflammation MediatorsbusinessHeLa CellsJournal of ethnopharmacology
researchProduct

Selective Sacral Nerve Blockade for the Treatment of Unstable Bladders

1987

38 patients with severe urge or urge incontinence, who did not respond to conservative therapy, were treated with selective sacral nerve blockade using a local anesthetic (bupivacaine). 6 patients of this group had definite selective sacral denervation with phenol. In 31 patients a urodynamic study was done previous to the sacral nerve block as well as 10 and 90 min after the injection. Within the first 2-7 weeks the success rate was about 70% in regard to bladder capacity and mean volume at first desire to void. On long-term follow-up (greater than 7 months), the success rate decreased to about 16%. Only 1 patient of the phenol group still has complete detrusor areflexia for now more than …

DenervationBupivacaineMalemedicine.medical_specialtyLocal anestheticmedicine.drug_classbusiness.industryUrologyBladder capacityNerve BlockMiddle AgedBupivacaineSurgeryBlockadeUrodynamicsUrinary IncontinenceDetrusor areflexiaPhenolsmedicineSuprapubic painSacral nerveHumansFemalebusinessmedicine.drugEuropean Urology
researchProduct

Dehydrogenative Anodic C−C Coupling of Phenols Bearing Electron‐Withdrawing Groups

2019

Abstract We herein present a metal‐free, electrosynthetic method that enables the direct dehydrogenative coupling reactions of phenols carrying electron‐withdrawing groups for the first time. The reactions are easy to conduct and scalable, as they are carried out in undivided cells and obviate the necessity for additional supporting electrolyte. As such, this conversion is efficient, practical, and thereby environmentally friendly, as production of waste is minimized. The method features a broad substrate scope, and a variety of functional groups are tolerated, providing easy access to precursors for novel polydentate ligands and even heterocycles such as dibenzofurans.

Denticityoxidation010405 organic chemistryChemistrySupporting electrolyteCommunicationC−C couplingoxygen heterocyclesSubstrate (chemistry)General Chemistry010402 general chemistryElectrochemistry01 natural sciencesEnvironmentally friendlyCombinatorial chemistryCommunicationsCatalysisCoupling reaction0104 chemical scienceschemistry.chemical_compoundElectrochemistry | Hot Paperelectrochemistrycross-couplingPolar effectPhenolsAngewandte Chemie International Edition
researchProduct

A direct Capillary Liquid Chromatography with electrochemical detection method for determination of phenols in water samples

2010

A fast and direct method based on the use of Capillary Liquid Chromatography (LC) with electrochemical (EC) detection has been described for phenols pollutants in water samples. Concretely, phenol, o-cresol, 2-chlorophenol and bisphenol A have been selected as target analytes. The combination of Capillary LC with EC detection avoided the necessity of preconcentration steps typically used in environmental analysis. The sample injected volume was 2 μL. The achieved detection limits were between 1 and 2 μg/L and the linear dynamic range was up to 50 μg/L for all studied phenols. The precision and uncertainty were satisfactory. The analysis time per sample was 10 min. The proposed procedure has…

Detection limitAnalyteChromatographyEnvironmental analysisCapillary actionOrganic ChemistryAnalytical chemistryReproducibility of ResultsFresh WaterGeneral MedicineSensitivity and SpecificityBiochemistryHigh-performance liquid chromatographyAnalytical Chemistrychemistry.chemical_compoundPhenolschemistryCapillary ElectrochromatographyLinear ModelsPhenolSeawaterPhenolsQuantitative analysis (chemistry)Water Pollutants ChemicalJournal of Chromatography A
researchProduct

Determination of phenolic antioxidants in vegetal and animal fats without previous extraction by dilution with n-propanol and micellar liquid chromat…

1999

Abstract A simple and rapid HPLC method for the determination of phenolic antioxidants (propyl and octyl gallates, tert -butylhydroquinone and 3- tert -butyl-4-hydroxyanisole) in sunflower, corn and olive oils, margarine, lard and butter oil is described. The samples are diluted with n -propanol, filtered and injected; solutions containing 30% (w/w) sample can be injected. The analytes are separated with a C18 column and a micellar mobile phase containing 0.1 M SDS, 2.5% n -propanol and 10 mM phosphate of pH 3, and detected at 290 nm. Calibration curves are linear ( r  > 0.9999) and the limits of detection range from 0.2 to 1.3 ng, which correspond to antioxidant concentrations well below t…

Detection limitAnimal fatChromatographyExtraction (chemistry)BiochemistryHigh-performance liquid chromatographyMicellar electrokinetic chromatographyAnalytical ChemistryPropanolchemistry.chemical_compoundchemistryMicellar liquid chromatographyEnvironmental ChemistryPhenolsSpectroscopyAnalytica Chimica Acta
researchProduct

COMPARATIVE STUDY OF C18- AND STYRENE-DIVINYLBENZENE-BASED SORBENTS FOR THE ENRICHMENT OF PHENOLS FROM WATER

2001

The potential of solid-phase extraction with C18- and styrene divinylbenzene-based sorbents for the preconcentration of phenols from water samples has been evaluated for a variety of phenols of different polarities: phenol, o-, m- and p-cresol, 2-chlorophenol, and 4-chloro-3-methylphenol. The extraction efficiencies have been calculated for different volumes of samples containing the analytes at different concentration levels. The UV limits of detection were of 1–5 ng/mL, for the method using Bond Elut C18 cartridges and sample volumes of 25 mL, and 0.05–0.1 ng/mL (except for 4-chloro-3-methylphenol) for the method using the polymeric sorbent Bond Elut PPL and 1000 mL of the samples. Possib…

Detection limitChromatographyClinical BiochemistryExtraction (chemistry)Pharmaceutical ScienceCresolDivinylbenzeneBiochemistryAnalytical ChemistryStyrenechemistry.chemical_compoundchemistrymedicineSample preparationSolid phase extractionPhenolsmedicine.drugJournal of Liquid Chromatography &amp; Related Technologies
researchProduct

Determination of phenolic compounds in air by using cyclodextrin-silica hybrid microporous composite samplers

2015

An analytical method for the determination of phenolic compounds in air samples based on the use of cyclodextrin-silica hybrid microporous composite samplers is proposed. The method allows the determination of phenol, guaiacol, cresol isomers, eugenol, 4-ethylphenol and 4-ethylguaiacol in workplaces according to the Norm UNE-EN 1076:2009 for active sampling. Therefore, the proposed method offers an alternative for the assessment of the occupational exposure to phenol and cresol isomers. The detection limits of the proposed method are lower than those for the NIOSH Method 2546. Storage time of samples almost reaches 44 days. Recovery values for phenol, guaiacol, o-cresol, m-cresol, p-cresol,…

Detection limitChromatographyCresolMicroporous materialAnalytical Chemistrylaw.inventionEugenolchemistry.chemical_compoundchemistrylawmedicinePhenolGuaiacolPhenolsEssential oilmedicine.drugTalanta
researchProduct