Search results for "PHOTONS"
showing 10 items of 164 documents
Model-Based Dose Calculation Algorithms for Brachytherapy Dosimetry
2019
The purpose of this study was to review the limitations of dose calculation formalisms for photon-emitting brachytherapy sources based on the American Association of Physicists in Medicine (AAPM) Task Group No. 43 (TG-43) report and to provide recommendations to transition to model-based dose calculation algorithms. Additionally, an overview of these algorithms and approaches is presented. The influence of tissue and seed/applicator heterogeneities on brachytherapy dose distributions for breast, gynecologic, head and neck, rectum, and prostate cancers as well as eye plaques and electronic brachytherapy treatments were investigated by comparing dose calculations based on the TG-43 formalism …
External photon radiation treatment for prostate cancer: Uncomplicated and cancer-free control probability assessment of 36 plans
2019
[Purpose] To perform a systematic and thorough assessment, using the Uncomplicated and Cancer-Free Control Probability (UCFCP) function, of a broad range of photon prostate cancer RT treatments, on the same scenario (a unique pelvic CT set). UCFCP considers, together with the probabilities of local tumour control (TCP) and deterministic (late) sequelae (NTCP), the second primary cancer risk (SPCR) due to photon and neutron peripheral doses.
PERIPHERAL SURFACE DOSE FROM A LINEAR ACCELERATOR: RADIOCHROMIC FILM EXPERIMENTAL MEASUREMENTS OF FLATTENING FILTER FREE VERSUS FLATTENED BEAMS
2020
Abstract There is a growing interest in the use of flattening filter free (FFF) beams due to the shorter treatment times. The reduction of head scatter suggests a better radiation protection to radiotherapy patients, considering the expected decrease in peripheral surface dose (PSD). In this work, PSD of flattened (FF) and FFF-photon beams was compared. A radiochromic film calibration method to reduce energy dependence was used. PSD was measured at distances from 2 to 50 cm to the field border for different square field sizes, modifying relevant clinical parameters. Also, clinical breast and prostate stereotactic body radiotherapy (SBRT) plans were studied. For square beams, FFF PSD is lowe…
Response charactterization of ammonium tartrate solid state pellets for ESR dosimetry with radiotherapeutic photon and electron beams.
2001
Solid state pellets (1 mm thick) for electron spin resonance (ESR) dosimetry were made using ammonium tartrate as the radiation-sensitive substance. Their behaviour was experimentally investigated as a function of dose with 60Co gamma rays. The calibration function obtained permits measurements of absorbed dose in the 2-50 Gy range, with a combined uncertainty of +/-4%. The lowest detectable dose was about 0.5 Gy. These properties are comparable with or even better than those of ESR dosimeters made from other materials. The time stability of the ESR signal of ammonium tartrate dosimeters at different storage conditions after irradiation was studied. A rather complex behaviour was observed, …
The Single Molecule Probe: Nanoscale Vectorial Mapping of Photonic Mode Density in a Metal Nanocavity
2009
International audience; We use superresolution single-molecule polarization and lifetime imaging to probe the local density of states (LDOS) in a metal nanocavity. Determination of the orientation of the molecular transition dipole allows us to retrieve the different LDOS behavior for parallel and perpendicular orientations with respect to the metal interfaces. For the perpendicular orientation, a strong lifetime reduction is observed for distances up to 150 nm from the cavity edge due to coupling to surface plasmon polariton modes in the metal. Contrarily, for the parallel orientation we observe lifetime variations resulting from coupling to characteristic λ/2 cavity modes. Our results are…
Octave-spanning ultraflat supercontinuum with soft-glass photonic crystal fibers
2009
We theoretically identify some photonic-crystal-fiber structures, made up of soft glass, that generate ultrawide (over an octave) and very smooth supercontinuum spectra when illuminated with femtosecond pulsed light. The design of the fiber geometry in order to reach a nearly ultraflattened normal dispersion behavior is crucial to accomplish the above goal. Our numerical simulations reveal that these supercontinuum sources show high stability and no significant changes are detected even for fairly large variations of the incident pulse. Ministerio de Ciencia e Innovación (TEC2008-05490) and Generalitat Valenciana (GV/2007/043).
Expanding Two-Photon Intravital Microscopy to the Infrared by Means of Optical Parametric Oscillator
2010
Chronic inflammation in various organs, such as the brain, implies that different subpopulations of immune cells interact with the cells of the target organ. To monitor this cellular communication both morphologically and functionally, the ability to visualize more than two colors in deep tissue is indispensable. Here, we demonstrate the pronounced power of optical parametric oscillator (OPO)-based two-photon laser scanning microscopy for dynamic intravital imaging in hardly accessible organs of the central nervous and of the immune system, with particular relevance for long-term investigations of pathological mechanisms (e.g., chronic neuroinflammation) necessitating the use of fluorescent…
ZnO-latex hybrids obtained by polymer-controlled crystallization: a spectroscopic investigation.
2007
Micro- and submicrosized ZnO-polymer hybrid materials were synthesized by precipitating zinc oxide from an aqueous medium in the presence of poly(styrene-acrylic acid) latex nanoparticles, prepared by miniemulsion polymerization. Up to 10 wt % of the latex becomes incorporated into the crystals. Although the long-range order of the inorganic material is essentially not altered by the polymer, studies by photoluminescence (PL) spectroscopy and electron paramagnetic resonance (EPR) show that the latex particles influence the optical and paramagnetic properties of the hybrids, which can be correlated with changes in the defect structure. Typical PL emission spectra showed a narrow UV peak and …
RADICAL DISTRIBUTIONS IN AMMONIUM TARTRATE SINGLE CRYSTALS EXPOSED TO PHOTON AND NEUTRON BEAMS
2014
The radiation therapy carried out by means of heavy charged particles (such as carbon ions) and neutrons is rapidly becoming widespread worldwide. The success of these radiation therapies relies on the high density of energy released by these particles or by secondary particles produced after primary interaction with matter. The biological damages produced by ionising radiations in tissues and cells depend more properly on the energy released per unit pathlength, which is the linear energy transfer and which determines the radiation quality. To improve the therapy effectiveness, it is necessary to grasp the mechanisms of free radical production and distribution after irradiation with these …
Ultrahigh-Q Tunable Whispering-Gallery-Mode Microresonator
2009
Typical microresonators exhibit a large frequency spacing between resonances and a limited tunability. This impedes their use in a large class of applications which require a resonance of the microcavity to coincide with a predetermined frequency. Here, we experimentally overcome this limitation with highly prolate-shaped whispering-gallery-mode "bottle microresonators" fabricated from standard optical glass fibers. Our resonators combine an ultra-high quality factor of 360 million, a small mode volume, and near lossless fibre coupling, characteristic of whispering-gallery-mode resonators, with a simple and customizable mode structure enabling full tunability.