Search results for "PIM"
showing 10 items of 3280 documents
Role of the Non-Canonical RNAi Pathway in the Antifungal Resistance and Virulence of Mucorales
2021
Mucorales are the causal agents for the lethal disease known as mucormycosis. Mortality rates of mucormycosis can reach up to 90%, due to the mucoralean antifungal drug resistance and the lack of effective therapies. A concerning urgency among the medical and scientific community claims to find targets for the development of new treatments. Here, we reviewed different studies describing the role and machinery of a novel non-canonical RNAi pathway (NCRIP) only conserved in Mucorales. Its non-canonical features are the independence of Dicer and Argonaute proteins. Conversely, NCRIP relies on RNA-dependent RNA Polymerases (RdRP) and an atypical ribonuclease III (RNase III). NCRIP regulates the…
Collecting and Using Students’ Digital Well-Being Data in Multidisciplinary Teaching
2018
This article examines how students (N=198; aged 13 to 17) experienced the new methods for sensor-based learning in multidisciplinary teaching in lower and upper secondary education that combine the use of new sensor technology and learning from self-produced well-being data. The aim was to explore how students perceived new methods from the point of view of their learning and did the teaching methods provide new information that could promote their own well-being. We also aimed to find out how to collect digital well-being data from a large number of students and how the collected big data set can be utilized to predict school success from the students’ well-being data by using machine lear…
Artificial Intelligence for Cybersecurity: A Systematic Mapping of Literature
2020
Due to the ever-increasing complexities in cybercrimes, there is the need for cybersecurity methods to be more robust and intelligent. This will make defense mechanisms to be capable of making real-time decisions that can effectively respond to sophisticated attacks. To support this, both researchers and practitioners need to be familiar with current methods of ensuring cybersecurity (CyberSec). In particular, the use of artificial intelligence for combating cybercrimes. However, there is lack of summaries on artificial intelligent methods for combating cybercrimes. To address this knowledge gap, this study sampled 131 articles from two main scholarly databases (ACM digital library and IEEE…
Recent advances in machine learning for maximal oxygen uptake (VO2 max) prediction : A review
2022
Maximal oxygen uptake (VO2 max) is the maximum amount of oxygen attainable by a person during exercise. VO2 max is used in different domains including sports and medical sciences and is usually measured during an incremental treadmill or cycle ergometer test. The drawback of directly measuring VO2 max using the maximal test is that it is expensive and requires a fixed and controlled protocol. During the last decade, various machine learning models have been developed for VO2 max prediction and numerous studies have attempted to predict VO2 max using data from submaximal and non-exercise tests. This article gives an overview of the machine learning models developed over the past five years (…
Predicting hospital associated disability from imbalanced data using supervised learning.
2019
Hospitalization of elderly patients can lead to serious adverse effects on their functional capability. Identifying the underlying factors leading to such adverse effects is an active area of medical research. The purpose of the current paper is to show the potential of artificial intelligence in the form of machine learning to complement the existing medical research. This is accomplished by studying the outcome of hospitalization of elderly patients as a supervised learning task. A rich set of features characterizing the medical and social situation of elderly patients is leveraged and using confusion matrices, association rule mining, and two different classes of supervised learning algo…
PBH assisted search for QCD axion dark matter
2022
The entropy production prior to BBN era is one of ways to prevent QCD axion with the decay constant $F_{a}\in[10^{12}{\rm GeV},10^{16}{\rm GeV}]$ from overclosing the universe when the misalignment angle is $\theta_{\rm i}=\mathcal{O}(1)$. As such, it is necessarily accompanied by an early matter-dominated era (EMD) provided the entropy production is achieved via the decay of a heavy particle. In this work, we consider the possibility of formation of primordial black holes during the EMD era with the assumption of the enhanced primordial scalar perturbation on small scales ($k>10^{4}{\rm Mpc}^{-1}$). In such a scenario, it is expected that PBHs with axion halo accretion develop to ultracomp…
Electroweak baryogenesis from a dark sector
2017
Adding an extra singlet scalar $S$ to the Higgs sector can provide a barrier at tree level between a false vacuum with restored electroweak symmetry and the true one. This has been demonstrated to readily give a strong phase transition as required for electroweak baryogenesis. We show that with the addition of a fermionic dark matter particle $\chi$ coupling to $S$, a simple UV-complete model can realize successful electroweak baryogenesis. The dark matter gets a CP asymmetry that is transferred to the standard model through a $CP\ portal\ interaction$, which we take to be a coupling of $\chi$ to $\tau$ leptons and an inert Higgs doublet. The CP asymmetry induced in left-handed $\tau$ lepto…
Particle size distributions of currently used pesticides in a rural atmosphere of France
2013
This work presents first data on the particle size distributions of current-used pesticides in the atmosphere. Ambient air samples were collected using a cascade impactor distributed into four size fractions in a rural site of Centre Region (France). Most pesticides were accumulated in the fine (0.1-1 mu m) particle size fraction such as cyprodinil, pendimethalin, fenpropidin, fenpropimorph and spiroxamine. Other pesticides such as acetochlor and metolachlor presented a bimodal distribution with maximum concentrations in the ultrafine (0.03-0.1 mu m) coarse (1-10 mu m) and in the ultrafine fine size ranges, respectively. No pesticides were detected in the size fraction >10 mu m. (C) 2013 El…
3 - 4 gadīgu bērnu sadarbības prasmju attīstības veicināšana rotaļās
2021
Darba nosaukums: 3 – 4 gadīgu bērnu sadarbības prasmju attīstības veicināšana rotaļās. Darba autore: Aļona Jansone Pētījuma mērķis: analizēt un pētīt rotaļas ietekmi uz sadarbības prasmju apguvi 3 – 4 gadus veciem bērniem. Pētījuma teorētiskā daļa balstās uz D.Dzinteres (2003, 2007)., I.Stangaines (2007, 2015), Ē.Kalvāna (2018)., D.Goulmena (2001)., K.Hansenas, R.Kaufmanes (2002)., R.Kaņepējas (2003, 2012)., D.Lieģenieces (1995, 1999)., S.A.Milleres (2020)., D.Nīmantes (2018)., G.Svences (1999) atziņām. Teorētiskajā daļā tika analizēti jautājumi par sadarbības procesu un sadarbības prasmēm un to iezīmēm, to attīstīšanas nozīmību un metodēm pirmsskolā. Rotaļas veidiem un likumsakarībām, rota…