Search results for "PLASMA"

The DAT ligand [(18)F]PR17.MZ mirrors the in vivo pharmacokinetic profile of [(11)C]cocaine with significantly improved monoamine transporter selecti…

2010

Efficient microwave-assisted direct radiosynthesis of [(18)F]PR04.MZ and [(18)F]LBT999: selective dopamine transporter ligands for quantitative molec…

2009

Abstract PR04.MZ 8-(4-fluoro-but-2-ynyl)-3- p -tolyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester ( 1 ) and LBT999 8-(( E )-4-fluoro-but-2-enyl)-3b- p -tolyl-8-aza-bicyclo[3.2.1]octane-2β-carboxylic acid methyl ester ( 2 ) are selective dopamine reuptake inhibitors, derived from cocaine. Compounds 1 and 2 were labelled with fluorine-18 at their terminally fluorinated N-substituents employing microwave enhanced direct nucleophilic fluorination. K[ 18 F]F − Kryptofix ® 222 cryptate, tetrabutyl ammonium [ 18 F]fluoride and caesium [ 18 F]fluoride were compared as fluoride sources under conventional and microwave enhanced conditions. Fluorination yields were remarkably increased un…

Oxygen-carrying v. non-oxygen-carrying colloidal blood substitutes in schock

1982

Loss of more than 10-15 per cent of the circulating blood causes a corresponding fall in filling pressure and a marked reduction in minute volume. In order to combat a fall in the minute volume, catecholamines are liberated, the stimulating components of these cause a rise in vessel tone. In spite of the blood volume being reduced by blood loss, filling pressure and minute volume are restored by compensating mechanisms as long as the volume lost is not enough to exceed the autoregulative capacity. Even with a blood loss of 10-15 per cent, full compensation is not achieved without replenishing the blood volume unless the fluid lost from the vascular bed is less than I0 per cent of the total.…

Comportamento di nanocompositi PA6/CNT in flusso elongazionale non isotermo

2012

Si sono preparate fibre a matrice poliammidica caricate con CNT. Sono state utilizzate due diverse tipologie di CNT a differente fattore di forma e grado di purezza, ossidate mediante plasma di ossigeno. Le misure di viscosità elongazionale hanno evidenziato che l’introduzione della carica comporta un incremento della MS a fronte di una diminuzione della BSR per tutti i materiali caricati. La tipologia e la funzionalizzazione dei CNT hanno delle notevoli ricadute sul diverso comportamento reologico. Studi morfologici hanno evidenziato che dopo la funzionalizzazione si registrano livelli di dispersione, allineamento e adesione interfacciale più alti. La natura delle interazioni matrice-caric…

Multilayer Network Model of Movie Script

2018

Network models have been increasingly used in the past years to support summarization and analysis of narratives, such as famous TV series, books and news. Inspired by social network analysis, most of these models focus on the characters at play. The network model well captures all characters interactions, giving a broad picture of the narration’s content. A few works went beyond by introducing additional semantic elements, always captured in a single layer network. In contrast, we introduce in this work a multilayer network model to capture more elements of the narration of a movie from its script: people, locations, and other semantic elements. This model enables new measures and insights…

Mild processing applied to the inactivation of the main foodborne bacterial pathogens: A review

2017

International audience; Salmonella, Listeria monocytogenes, Escherichia coli O157:H7 and Campylobacter are the major bacterial pathogens associated with foodborne diseases and their inactivation is fundamental to ensure microbiologically safe products. Although efficient in generating safe foods with proper shelf-lives, pasteurization and commercial sterilization may result in numerous nutritional and sensory changes in foods. To address these disadvantages, mild processing methods (i.e., processing technologies for food preservation that apply mild temperature; <40 °C) aiming to destroy microbial food contaminants have been developed.Scope and approachThis review emphasizes the main applic…

Emerging macroscopic pretreatment

2021

Macroscopic pretreatment of food waste aims at the preparation of the food matrix for subsequent processing and recovery steps. The preparatory steps involve the adjustment of the phase content and properties (water, solid, fats content), the moderation of enzyme activity as well as prevention and control of any microbial growth (Galanakis, 2012; Galanakis et al., 2010a). In recent times, several emerging technologies have been researched, developed, and/or adapted from other fields for drying, sterilization, enzyme inactivation, and enhancing mass transfer in food and biomaterials. This chapter focuses on these upcoming technologies with potential applications to food waste recovery and in…

Glass Transition and Glass Dynamics

2014

The transition from an undercooled liquid towards a glass (glass transition) is introduced and discussed in terms of mode-coupling theory. It is demonstrated that mode-coupling theory leads to a two-step relaxation scenario near the transition with time-critical exponents, which characterize the two relaxation steps (beta and alpha relaxation). The anomalous vibrational properties of a disordered solid (glass) is explained in terms of a model with spatially fluctuating harmonic force constants.

Capillary electrophoresis–inductively coupled plasma-mass spectrometry hyphenation for the determination at the nanogram scale of metal affinities an…

2012

Abstract A screening strategy based on hyphenated capillary electrophoresis and inductively coupled plasma mass spectrometry (CE–ICP-MS) was developed to classify phosphorylated ligands according to their europium(III) binding affinity in a hydro-organic medium (sodium formate, pH 3.7, H2O/MeOH 90:10, v/v). Taking advantage of the high sensibility of ICP-MS for detecting phosphorus, this method enabled to assess the affinity of a variety of phosphorylated compounds, including phosphine oxides, thiophosphines, phosphonates, and phosphinates, in less than 1 h and using less than 5 ng of substance. By varying the total europium concentration, complexation constants could be determined accordin…

Nuclear hyperpolarization of 3He by magnetized plasmas

2018

International audience; We describe a method, referred to as PAMP (polarization of atoms in a magnetized plasma), that allowshyperpolarization of 3He nuclear spins at high magnetic field solely by excitation of a rf gas discharge.A magnetized plasma is obtained when the mean free path of the free electrons is much larger than theirgyration radius in the rf gas discharge. Investigations of PAMP are carried out in the 1–15-mbar pressure rangewith rf excitation around 100 MHz. Quantitative NMR measurements at 4.7 T and room temperature showthat, for different cell sizes and gas densities, 3He nuclear polarizations in the 1 to 9% range are achieved(i.e., larger than the Boltzmann equilibrium sp…