Search results for "PPD"
showing 10 items of 20 documents
Ratiometric fluorescence live imaging analysis of membrane lipid order in Arabidopsis mitotic cells using a lipid order-sensitive probe
2016
SPE Pôle IPM; International audience; Eukaryotic cells contain membranes exhibiting different levels of lipid order mostly related to their relative amount of sterol-rich domains, thought to mediate temporal and spatial organization of cellular processes. We previously provided evidence in Arabidopsis thaliana that sterols are crucial for execution of cytokinesis, the last stage of cell division. Recently, we used di-4-ANEPPDHQ, a fluorescent probe sensitive to order of lipid phases, to quantify the level of membrane order of the cell plate, the membrane structure separating daughter cells during somatic cytokinesis of higher plant cells. By employing quantitative, ratiometric fluorescence …
The Burden of Respiratory Syncytial Virus Disease in Pre-Term Infants
2015
This mini-review summarises the risk factors for acquiring Respiratory Syncitial Virus (RSV) infection, and describes the harmful effects of the infection in pre-term infants. Moreover, theoretical considerations are discussed for the prevention of RSV infection in high-risk infant categories, such as pre-term infants. Background: Neonates positive for RSV are more prone to severe infection than neonates infected with other common respiratory viruses. Despite RSV infection being more common in late neonates than in early ones, pre-term infants ≤ 35 wk gestational age (GA) are at high risk for developing severe RSV disease. Efforts to prevent infection include case management, vaccination an…
Docking and synthesis of pyrrolopyrimidodiazepinone derivatives (PPDs) and their precursors: New scaffolds for DNA-interacting agents
2007
New classes of pyrrolopyrimidodiazepinone derivatives (PPDs) and their precursors were studied in silico for their ability to form stable complex with DNA fragment. In the docking studies two binding modes can be envisaged: groove mode and intercalating mode. In the case of the best ligands the docking studies revealed a common binding mode with the chromophore intercalated between GC base pairs whereas the side chain lies close to the minor groove. Synthetic approach to the PPD ring systems is discussed.
Analysis of Thermal Comfort Conditions and Actual Energy Efficiency for Different Heating Systems in Test Buildings
2015
The aim of this study is detailed analysis of long-term monitoring data on thermal comfort conditions and energy efficiency in small test buildings equipped with different heating systems. Calculations of PPD index and local thermal discomfort factors, as well as actual energy efficiency ratios for different heat pump systems are provided for the test buildings during three weeks of the heating season. It is shown that the type of heating system has an influence not only on heating energy needs, but also on thermal comfort conditions in the room.
Experimental Research of Thermal Comfort Conditions in Small Test Buildings with Different Types of Heating
2015
Abstract The aim of this study is detailed analysis of long-term monitoring data of thermal comfort conditions and energy efficiency in small test buildings equipped with different heating systems. Calculations of PPD index and local thermal discomfort factors are provided for the test buildings during three weeks of heating season. It is shown that the type of heating system has influence not only on heating energy need, but also on thermal comfort conditions in the room.
Thermo-hygrometric comfort in the lecture hall of a library: methodology and experimental evidence.
2012
The present study verifies the thermo hygrometric comfort conditions in subjects of a university library users, evaluating the differences and peculiarities in the data collected at the measurement campaign. Particularities of the investigation is the period studied concerning the time frame of the Middle season, which is not expected to power the air conditioning systems. Based on assumptions on the thermal resistance of clothing in the spring and the metabolic type of subjects, the environmental parameters were monitored in some work position in the reading hall in the library of the Faculty of Medicine and Surgery of the University of Palermo. The article presents analyses of the measure…
Effects of cyber domain in crisis management
2019
There is fundamental need in EU-level to develop common alarm procedures and emergency response models with preventive functions which work well from local to national level and from national to international level. European Public Protection and Disaster Relief (PPDR) services such as law enforcement, firefighting, emergency medical and disaster recovery services have recognized that lack of interoperability of technical systems limits cooperation between the PPDR authorities. Also, the military (MIL) and critical infrastructure protection (CIP) faces similar challenges. Recent major accidents have indicated that lack of human resources affects to disaster recovery. PPDR-actors cannot star…
The calculation of the mean radiant temperature of a subject exposed to the solar radiation – A generalised algorithm
2005
Abstract The thermal sensation experienced by a subject in a confined environment is significantly affected by the radiative heat exchange between the human body and the surrounding surfaces: it contributes as far as 30% of the whole thermal exchanges of the subject. Besides, the presence of high-intensity radiation sources like, for example, the sun, may appreciably modify the radiant field to which people are exposed. As a consequence, this could alter notably the comfort conditions. In order of properly taking into account this issue, a simple analytical method is introduced in this work, that allows the easy evaluation of the thermal radiant field induced by the presence of the solar ra…
Evaluation through adaptive model (ATC) in the levels of thermal comfort in summer in offices in Mediterranea locations.
2014
The design of the building-plant system in the case of office buildings has rarely considered the adaptive model of comfort almost always limited to the control of temperature and humidity and only in some cases of PMV and PPD. Specifically when the building interacts with a climate characterized by high values of external temperature and humidity for long periods, and with high solar radiation in the presence of large glazed areas, it is crucial to take into account relevant aspects of the principle of thermal adaptation. The long stay of the occupants in an air-conditioned environment leads, at the request of colder temperatures very distant from those indicated by the criteria of accepta…
A new tool to assess the ecotoxicological impact of β-triketone herbicides on soil microbial communities
2018
International audience; The β-triketone herbicides are post-emergence maize selective herbicides that have beenintroduced on the market, in replacement of atrazine, banned in Europe in 2004. Qualified as “eco-friendly”, since they are based on natural phytotoxin properties, these herbicides target an enzymeinvolved in carotenoid biosynthesis called 4-hydroxyphenylpyruvate dioxygenase (HPPD) encoded bythe hppd gene. The inhibition of this enzyme provokes bleaching symptoms, necrosis and death ofweeds.The hppd gene is not only find in eukaryotes such as plants, animals and humans but also inprokaryotes such as fungi, yeasts and bacteria. In recent studies, we showed that, within the soil bact…