Search results for "PRIORITY"

showing 10 items of 149 documents

Multilocus microsatellite analysis of European and African Candida glabrata isolates

2016

This study aimed to elucidate the genetic relatedness and epidemiology of 127 clinical and environmental Candida glabrata isolates from Europe and Africa using multilocus microsatellite analysis. Each isolate was first identified using phenotypic and molecular methods and subsequently, six unlinked microsatellite loci were analyzed using automated fluorescent genotyping. Genetic relationships were estimated using the minimum-spanning tree (MStree) method. Microsatellite analyses revealed the existence of 47 different genotypes. The fungal population showed an irregular distribution owing to the over-representation of genetically different infectious haplotypes. The most common genotype was …

0301 basic medicineSettore MED/07 - Microbiologia E Microbiologia ClinicaClonal complexEpidemiologyMultilocus microsatellite analysisCandida glabrataMolecular phylogenyGene locusCentral typeRelated genotypeGenotypeEnvironmental MicrobiologyHaplotypeDNA FungalPriority journalGeneticsAlleleCandidiasisGeneral MedicineClassificationEuropePhenotypeInfectious DiseasesCandida Glabrata; Adhesins; FluconazoleCandidiasiMicrosatelliteMicrosatellite RepeatMicrobiological examinationHumanMicrobiology (medical)GenotypeSettore MED/17 - Malattie InfettiveMicrosatellite DNA030106 microbiologyBiologyEuropeanMicrobiologyArticle03 medical and health sciencesGenetic variationMicrosatellite repeatsGeneticsHumansAlleleGenotypingAllelesScience & TechnologyCandida glabrataMicrosatellite markerHaplotypeAfricanGenetic Variationbiology.organism_classificationNonhuman030104 developmental biologyFungal DNAHaplotypesIsolation and purificationGenetic LociAfricaMultilocus sequence typingFungus isolationGenetic variabilityMicrosatellite genotypeMultilocus Sequence Typing
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Dysregulation of C-X-C motif ligand 10 during aging and association with cognitive performance

2017

International audience; Chronic low-grade inflammation during aging (inflammaging) is associated with cognitive decline and neurodegeneration; however, the mechanisms underlying inflammaging are unclear. We studied a population (n = 361) of healthy young and old adults from the MyoAge cohort. Peripheral levels of C-X-C motif chemokine ligand 10 (CXCL10) was found to be higher in older adults, compared with young, and negatively associated with working memory performance. This coincided with an age-related reduction in blood DNA methylation at specific CpGs within the CXCL10 gene promoter. In vitro analysis supported the role of DNA methylation in regulating CXCL10 transcription. A polymorph…

0301 basic medicinegamma interferon inducible protein 10genomic DNAAlzheimerin tautiEpigenesis GeneticCohort StudiesCXCL10 geneCognitionsingle nucleotide polymorphismcognitive defectCognitive declineAged 80 and overCerebral Cortexeducation.field_of_studyprefrontal cortexDNA methylationGeneral NeuroscienceadultNeurodegenerationneurodegenerationta3141U937 CellsMethylationta3142Alzheimer's diseasecohort analysisDNA-metylaatioagedfemalepriority journalepigenetiikkaDNA methylationAlzheimer's diseaseAlzheimer diseasetranscription regulationAlzheimer’s diseasekognitiiviset taidotmedicine.medical_specialty[SDV.MHEP.AHA] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]in vitro studyAdolescentheredityPopulationBiologyArticleworking memoryYoung Adult03 medical and health sciencesCognitive agingpromoter regionmaleMemoryInternal medicineJournal Articlemedicine[SDV.MHEP.AHA]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]HumansCXCL10controlled studyEpigeneticshumanbrain levelNeurodegenerationeducationepigeneticscognitive aginghuman cellagingdisease associationmedicine.diseasemajor clinical studyInflammagingChemokine CXCL10gamma interferon inducible protein 10; genomic DNA adult; age; aged; aging; Alzheimer disease; Article; brain level; cognitive defect; cohort analysis; controlled study; CpG island; CXCL10 gene; disease association; DNA methylation; epigenetics; female; heredity; human; human cell; in vitro study; inflammation; major clinical study; male; prefrontal cortex; priority journal; promoter region; single nucleotide polymorphism; transcription regulation; working memory; Alzheimer's disease; Cognitive aging; DNA methylation; Epigenetics; Inflammaging; Neurodegeneration030104 developmental biologyEndocrinologyikääntyminenageinflammationNerve DegenerationCpG islandinflammagingNeurology (clinical)Geriatrics and GerontologyHeLa CellsDevelopmental BiologyNeurobiology of Aging
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Giant hepatocellular adenoma as cause of severe abdominal pain: a case report

2007

Abstract The authors describe the case of a large hepatocellular adenoma diagnosed in a 30-year old woman who came to us complaining of acute pain in the upper abdominal quadrants. The patient had been taking an oral contraceptive pill for the last ten years. We present the clinical features, the diagnostic work-up and the treatment prescribed.

Abdominal painPathologyoral contraceptive agent EMTREE medical terms: abdominal painanamnesilcsh:Medicinecomputer assisted tomographyaspartate aminotransferaseSurgical oncologynuclear magnetic resonance imagingMedicine(all)oral contraceptionadultarticleGeneral MedicineAbdominal quadrantsfemalepriority journalhistopathologycontrast enhancementdisease severitymedicine.symptomEMTREE drug terms: alanine aminotransferasemedicine.medical_specialtyOral contraceptive pillcontrast mediummedicinediffusion weighted imagingcase reportfollow uphumanAcute painliver biopsydrug useliver lobectomybusiness.industryGeneral surgeryPublic healthlcsh:RechographyHepatocellular adenomaliver angiographymedicine.diseasetumor bleedinghuman tissueclinical featurenausea and vomitingbusinessaspartate aminotransferase blood levelliver adenomaalanine aminotransferase blood level
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Metabolic shift of polyphosphate-accumulating organisms with different levels of polyphosphate storage

2012

Previous studies have shown that polyphosphate-accumulating organisms (PAOs) are able to behave as glycogen-accumulating organisms (GAOs) under different conditions. In this study we investigated the behavior of a culture enriched with Accumulibacter at different levels of polyphosphate (poly-P) storage. The results of stoichiometric ratios Gly degraded/HAc uptake, PHB synthesized/HAc uptake, PHV synthesized/HAc uptake and P release/HAc uptake confirmed a metabolic shift from PAO metabolism to GAO metabolism: PAOs with high poly-P content used the poly-P to obtain adenosine tri-phosphate (ATP), and glycogen (Gly) to obtain nicotinamide adenine dinucleotide (NADH) and some ATP. In a test whe…

Accumulibacter Type IIWaste component removalUnclassified drugPhysiologyChemical compositionMicrobial metabolismStorageWastewaterNicotinamide adenine dinucleotidePolyhydroxyalkanoic acidchemistry.chemical_compoundBacteriumBioreactorsPolyphosphatesGlycolysisAnaerobiosisBiomassPolyphosphate-accumulating organismsWaste Management and DisposalAccumulibacter Type IGlycogen accumulating organismPriority journalWater Science and TechnologyFluorescence microscopyPolyhydroxyvalerateSewageGlycogenHydrolysisFluorescence in situ hybridizationEcological ModelingPhosphorusHydrogen-Ion ConcentrationBioaccumulationPollutionStoichiometryWaste treatmentPolyphosphate-accumulating organismsBiodegradation EnvironmentalEnhanced biological phosphorus removalBiochemistryGlycogen-accumulating metabolism (GAM)Nicotinamide adenine dinucleotideAccumulibacter type 1Accumulibacter type 2GlycolysisGlycogenMetabolic Networks and PathwaysAccumulibacterAdenosine triphosphateEnvironmental EngineeringBiologyAcetic acidArticleAssociative storagePolyphosphate-accumulating metabolism (PAM)PolyphosphateGlycogen-accumulating organismsGlycogen-accumulating metabolismsTECNOLOGIA DEL MEDIO AMBIENTEPolyphosphate accumulating organismCivil and Structural EngineeringPolyphosphate-accumulating organisms (PAO)BacteriaPolyphosphateMetabolismIn situ measurementGlycogen-accumulating organisms (GAO)Polyphosphate-accumulating metabolismsNonhumanAmidesCarbonMetabolismchemistryPolyphosphate (poly-P)Bacterial metabolismCell cultureVolatilizationWater Research
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Aequorin-expressing yeast emits light under electric control

2011

In this study, we show the use of direct external electrical stimulation of a jellyfish luminescent calcium-activated protein, aequorin, expressed in a transgenic yeast strain. Yeast cultures were electrically stimulated through two electrodes coupled to a standard power generator. Even low (1.5. V) electric pulses triggered a rapid light peak and serial light pulses were obtained after electric pulses were applied periodically, suggesting that the system is re-enacted after a short refraction time. These results open up a new scenario, in the very interphase between synthetic biology and cybernetics, in which complex cellular behavior might be subjected to electrical control.

Activated proteinsLightScyphozoaAequorinApplied Microbiology and BiotechnologyElectricityHydroxidesCellular behaviorsPriority journalYeast electro-stimulationbiologyPhosphorescencePower generatorsGeneral MedicineElectrostimulationMAQUINAS Y MOTORES TERMICOSElectrodeElectric pulseInterphaseBioluminescenceYeast cultureGenetic EngineeringMATEMATICA APLICADABiotechnologyPotassium CompoundsLight pulse generatorsSaccharomyces cerevisiaeBioengineeringNanotechnologyLight pulseSaccharomyces cerevisiaeElectrical stimulationsYeast strainArticleAequorinBioluminescenceBiologySynthetic biologyBioelectronicsBioelectronicsbiology.organism_classificationElectric controlYeastElectric StimulationYeastFISICA APLICADABiophysicsbiology.proteinProtein expressionJellyfishElectrical controlLuminescenceCell functionTransgenics
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Specific transfer effects following variable priority dual-task training in older adults

2016

International audience; Purpose: Past divided attention training studies in older adults have suggested that variable priority training (VPT) tends to show larger improvement than fixed priority training (FPT). However, it remains unclear whether VPT leads to larger transfer effects. Methods: In this study, eighty-three older adults aged between 55 and 65 received five 1-hour sessions of VPT, FPT or of an active placebo. VPT and FPT subjects trained on a complex dual-task condition with variable stimulus timings in order to promote more flexible and self-guided strategies with regard to attentional priority devoted to the concurrent tasks. Real-time individualized feedback was provided to e…

Active placeboMalemedicine.medical_specialtyAgingComputer User TrainingTransfertTransfer Psychology[ SCCO.PSYC ] Cognitive science/PsychologyStimulus (physiology)Neuropsychological Tests050105 experimental psychology[ SDV.NEU.PC ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationDiscrimination PsychologicalDevelopmental NeuroscienceComputer User TrainingmedicineReaction TimeHumans0501 psychology and cognitive sciencesAttentionAgedAnalysis of Variance[SDV.NEU.PC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behaviorTeaching[SCCO.NEUR]Cognitive science/Neuroscience05 social sciencesMiddle AgedDivided attentionCognitive trainingVariable priority trainingNeurologyPattern Recognition VisualCognitive trainingDivided attentionOlder adults[SCCO.PSYC]Cognitive science/Psychology[ SCCO.NEUR ] Cognitive science/NeuroscienceFemaleNeurology (clinical)Analysis of varianceIndependent LivingPsychology030217 neurology & neurosurgery
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Schedulability analysis of window-constrained execution time tasks for real-time control

2003

Feasibility tests for hard real-time systems provide information about the schedulability of a set of tasks. However, this information is a yes or no answer whether the task set achieves the test or not. From the system design point of view, it would be useful to have more information, for example, how much can one vary some task parameters, such as computation time, without jeopardizing the system feasibility. The aim of the work is to provide a method to determine how much a task can increase its computation time, maintaining the system feasibility under a dynamic priority scheduling. This extra time can be determined not only in all the task activations, but in n of a window of m task in…

Adaptive controlJob shop schedulingReal-time Control SystemComputer scienceControl systemReal-time computingSystems designFault toleranceDynamic priority schedulingScheduling (computing)Proceedings 14th Euromicro Conference on Real-Time Systems. Euromicro RTS 2002
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Assessment of maximal handgrip strength: How many attempts are needed?

2017

BACKGROUND: Handgrip strength (HGS) is used to identify individuals with low muscle strength (dynapenia). The influence of the number of attempts on maximal HGS is not yet known and may differ depending on age and health status. This study aimed to assess how many attempts of HGS are required to obtain maximal HGS.METHODS: Three cohorts (939 individuals) differing in age and health status were included. HGS was assessed three times and explored as continuous and dichotomous variable. Paired t-test, intraclass correlation coefficients (ICC) and Bland-Altman analysis were used to test reproducibility of HGS. The number of individuals with misclassified dynapenia at attempts 1 and 2 with respe…

AdultSarcopeniaAdolescentsex differenceHealth Statusadult; aged; aging; Article; cohort analysis; dual energy X ray absorptiometry; dynamometer; female; four minute walk test; geriatric assessment; grip strength; health status; human; major clinical study; male; middle aged; muscle strength; outpatient; priority journal; reproducibility; sarcopenia; sex difference; six minute walk test; walk test; walking speed; X ray bone densitometer; Aged; Geriatric assessment; Muscle strength; Reproducibility of Results; Sarcopeniahealth statuswalking speedArticlesarcopeniaCohort StudiesYoung Adultmalesix minute walk testmiddle aged80 and overHumansfour minute walk testhumanMuscle StrengthreproducibilityGeriatric AssessmentX ray bone densitometerAgedAged 80 and overdual energy X ray absorptiometryHand StrengthMuscle strengthadultwalk testagingAge FactorsReproducibility of ResultsOriginal ArticlesdynamometerMiddle Agedcohort analysismajor clinical studyGeriatric assessmentfemaleCross-Sectional Studiespriority journalgrip strengthoutpatientOriginal Articlelihasvoima
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Closedness properties in team learning of recursive functions

1997

This paper investigates closedness properties in relation with team learning of total recursive functions. One of the first problems solved for any new identification types is the following: “Does the identifiability of classes U1 and U2 imply the identifiability of U1∪U2?” In this paper we are interested in a more general question: “Does the identifiability of every union of n−1 classes out of U1,...,Un imply the identifiability of U1∪...∪Un?” If the answer is positive, we call such identification type n-closed. We show that n-closedness can be equivalently formulated in terms of team learning. After that we find for which n team identification in the limit and team finite identification t…

AlgebraIdentification (information)Mathematical optimizationTeam learningRelation (database)IdentifiabilityLimit (mathematics)Inductive reasoningType (model theory)Priority queueMathematics
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On the formation of inclusion complexes at the solid/liquid interface of anchored temperature-responsive PNIPAAM diblock copolymers with γ-cyclodextr…

2017

The thermal responsive behavior of adsorbed layers of diblock copolymers of poly(N-isopropylacrylamide) (PNIPAAM) and poly((3-acrylamidopropyl)trimethylammonium chloride) (PAMPTMA(+)) with γ-cyclodextrin (γ-CD) at the solid/liquid interface has been investigated using three in situ techniques: null ellipsometry, quartz–crystal microbalance with dissipation monitoring, and neutron reflectometry. The measurements provided information about the adsorbed amounts, the layer thickness, hydration and viscoelastic properties, and the interfacial structure and composition. The copolymers adsorb to silica with the cationic PAMPTMA(+) blocks sitting as anchors in a flat conformation and the PNIPAAM ch…

AmidePolymers and PlasticsBlock copolymerReflectometerReflection02 engineering and technology01 natural sciencessupramolecular chemistryquartz crystal microbalancechemistry.chemical_compoundColloid and Surface ChemistryEllipsometryViscoelasticity Inclusion complexCopolymerMaterials ChemistryPoly (n isopropylacrylamide)Poly(N-isopropylacrylamide)Settore CHIM/02 - Chimica Fisicachemistry.chemical_classification/dk/atira/pure/subjectarea/asjc/1600/1606Reflectometry/dk/atira/pure/subjectarea/asjc/1500/1505Cyclodextrinunclassified drug Article021001 nanoscience & nanotechnologyThermoresponsive block copolymerpriority journalsolidpolymerizationPoly(N-isopropylacrylamide)synthesiNeutron reflectometrypolyrotaxane0210 nano-technologyellipsometryMaterials science/dk/atira/pure/subjectarea/asjc/2500/2505/dk/atira/pure/subjectarea/asjc/2500/2507poly(n isopropylacrylamide)010402 general chemistryLower critical solution temperatureAcrylic monomeratom transfer radical polymerizationAdsorptioncomplex formationPolymer chemistryCyclodextrinliquidPhysical and Theoretical ChemistrySolid/liquid interfaceThermo-responsive Hydrogels copolymerneutron reflectometryInclusion complexgamma cyclodextrinCationic polymerization0104 chemical sciencessolid liquid interfacechemistryChemical engineeringInvited ArticleColloid and Polymer Science
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