Search results for "PSO"

showing 10 items of 679 documents

Relationship between clinical variables and Patient-Reported Outcomes in patients with psoriatic disease

2021

Background Psoriatic Arthritis (PsA) is a chronic inflammatory form of Arthritis associated with enthesitis, dactylitis, nail dystrophy, uveitis, and osteitis. PsA is strongly associated with comorbidities such as obesity, metabolic syndrome, and cardiovascular disease. As usual PsA patients are assessed either by rheumatologist or dermatologist but a multiprofessional assessment for those subjects is important to improve their disease control and their quality-of-life. The multidimensional assessment is a new model of care for PsA patients in which a multiprofessional team (rheumatologist, dermatologist, internal medicine physician, nutritionist and a phycologist) with a nurse as case mana…

Quality-of-lifeNursingPsoriatic ArthritiCentral ObesityPatient-Reported-OutcomeSettore MED/45 - Scienze Infermieristiche Generali Cliniche E Pediatriche
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Rapid prototyping platform for stream-oriented reconfigurable computing applications

2010

In this paper we present a methodology and tool for rapid prototyping of real time image processing applications. We describe our design flow of multiprocessor system on chip (MPSoC) architectures based on hardware/software components. This methodology provides automated methods to specify, generate the hardware, software, and the architectural interfaces between them. Our methodology starts from system level specification of the application with parallel processes described in C-code. The processes communicate through an abstract channel called streams. We describe also the solution that we proposed to synthesize a custom bus architecture for the reconfigurable computing applications, whic…

Rapid prototypingHardware architectureSoftwareComputer architecturebusiness.industryComputer scienceEmbedded systemComponent-based software engineeringSystem on a chipMPSoCField-programmable gate arraybusinessReconfigurable computingInternational Conference on Computer and Communication Engineering (ICCCE'10)
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Successive Reduction of Arms in Multi-Armed Bandits

2011

The relevance of the multi-armed bandit problem has risen in the past few years with the need for online optimization techniques in Internet systems, such as online advertisement and news article recommendation. At the same time, these applications reveal that state-of-the-art solution schemes do not scale well with the number of bandit arms. In this paper, we present two types of Successive Reduction (SR) strategies - 1) Successive Reduction Hoeffding (SRH) and 2) Successive Reduction Order Statistics (SRO). Both use an Order Statistics based Thompson Sampling method for arm selection, and then successively eliminate bandit arms from consideration based on a confidence threshold. While SRH…

Reduction (complexity)Mathematical optimizationComputer scienceOrder statisticScalabilitySampling (statistics)Pairwise comparisonScale (descriptive set theory)Thompson samplingSelection (genetic algorithm)
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Gravity Anomalies and Disturbances: Reductions and Analyses

2009

Reference ellipsoidGeodesyGeologyBouguer anomalyGravity anomaly
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Latent tubercolosis infection in patients with cronic plaque psoriasis: evidence from the Italian Psocare Registry

2015

SummaryBackground The nationwide prevalence of latent tuberculosis infection (LTBI) in Italian patients with psoriasis has never been investigated. Objectives To estimate the nationwide prevalence of LTBI in Italian patients with psoriasis who are candidates for systemic treatment. Methods Data were obtained from the Psocare Registry on those patients (n = 4946) with age > 18 years, systemic treatment at entry specified and tuberculin skin test (TST) performed according to the Mantoux method. LTBI diagnosis was based on a positive TST result in the absence of any clinical, radiological or microbiological evidence of active tuberculosis. Results Latent tuberculosis infection was diagnosed in…

RegistrieMaletaiwanAntitubercular AgentsBiological Factorquantiferon-tb-goldAntitubercular AgentBiological FactorsexperienceResidence Characteristics80 and overPrevalenceRegistriesYoung adultriskAged 80 and overLatent TuberculosiLatent tuberculosispsoriasisMiddle AgedItalyFemaletubercolosistubercolosiAdolescent; Adult; Age Distribution; Aged; Aged 80 and over; Antitubercular Agents; Biological Factors; Chronic Disease; Female; Humans; Italy; Latent Tuberculosis; Male; Middle Aged; PUVA Therapy; Prevalence; Psoriasis; Registries; Residence Characteristics; Sex Distribution; Tuberculin Test; Young Adult; 2708Humanmedicine.drugAdultmedicine.medical_specialtyAdolescentchronic plaque psoriasisTuberculinconsensus statementtubercolosis; psoriasisDermatology.Young Adulttuberculosis infectionSettore MED/35Age DistributionLatent TuberculosisInternal medicinePsoriasismedicineAdalimumabfactor antagonistsHumansPsoriasisnecrosis-factor blockers; quantiferon-tb-gold; consensus statement; factor antagonists; systemic treatment; therapy; experience;taiwan; assay; risknecrosis-factor blockersSex DistributionAdolescent; Adult; Age Distribution; Aged; Aged 80 and over; Antitubercular Agents; Biological Factors; Chronic Disease; Female; Humans; Italy; Latent Tuberculosis; Male; Middle Aged; PUVA Therapy; Prevalence; Psoriasis; Registries; Residence Characteristics; Sex Distribution; Tuberculin Test; Young AdultPUVA TherapyAgedPsoriasiHistory of tuberculosistherapytuberculosis infection chronic plaque psoriasisItalian Psocare Registrybusiness.industryTuberculin TestOdds ratiosystemic treatmentassaymedicine.diseasebacterial infections and mycosesConfidence intervalSurgeryResidence CharacteristicChronic DiseaseItalian Psocare Registrybusiness2708
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Soil organic carbon stocks assessment in Mediterranean natural areas: A comparison of entire soil profiles and soil control sections

2015

Soil organic carbon (SOC) is an important part of the global carbon (C) cycle. In addition, SOC is a soil property subject to changes and highly variable in space and time. Over time, some researches have analyzed entire soil profile (ESP) by pedogenetic horizons and other researches have analyzed soil control sections (SCS) to different thickness. However, very few studies compare both methods (ESP versus SCS). This research sought to analyze the SOC stock (SOCS) variability using both methods (ESP and SCS) in The Despeñaperros Natural Park, a nature reserve that consists of a 76.8 km(2) forested area in southern Spain. Thirty-four sampling points were selected in the study zone. Each samp…

RegosolHydrologyMediterranean climateTopsoilEnvironmental EngineeringSoil scienceGeneral MedicineSoil carbonForestsManagement Monitoring Policy and LawCarbonSoilSpainForest ecologySoil waterSoil organic carbon stocksHumansSoil horizonEnvironmental scienceWaste Management and DisposalJournal of Environmental Management
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A real-world economic analysis of biologic therapies for moderate-to-severe plaque psoriasis in Italy: results of the CANOVA observational longitudin…

2021

AbstractBackgroundPsoriasis is a chronic immune-mediated inflammatory skin disease which can also involve joints. It is often associated with burdensome comorbidities which negatively impact prognosis and quality of life (QoL). Biologic agents have been shown to be effective in controlling disease progression, but their use is associated with higher costs compared with traditional systemic treatments. The economic analysis of the CANOVA (EffeCtiveness of biologic treAtmeNts for plaque psOriasis in Italy: an obserVAtional longitudinal study of real-life clinical practice) study aims to assess the costs and cost-effectiveness of biologics in a real-world context in Italy.MethodsThe annualised…

Response ratemedicine.medical_specialtyCost per responderBiologicCostIxekizumabLongitudinal StudieContext (language use)Secukinumab.Severity of Illness IndexAntibodiesIndirect costsSettore MED/35Quality of lifeInternal medicinePsoriasisUstekinumabMonoclonalAdalimumab; Ixekizumab; Antibodies Monoclonal; Longitudinal Studies; Quality of Life; Psoriasis; Treatment Outcome; Severity of Illness Index; Italy; Humans; Biological Therapy; Ustekinumab; Secukinumab; Response rate; Real-world; Ixekizumab; Cost per responder; BiologicmedicineAdalimumabHumansPsoriasisLongitudinal Studieshealth care economics and organizationsSecukinumabPsoriasiAdalimumab; Biologic; Cost per responder; Costs; Ixekizumab; Real-world; Response rate; Secukinumab; Ustekinumab; Antibodies Monoclonal; Biological Therapy; Humans; Italy; Longitudinal Studies; Severity of Illness Index; Treatment Outcome; Psoriasis; Quality of Lifebusiness.industryHealth PolicyResearchAdalimumabAntibodies Monoclonalmedicine.diseaseCostsBiological TherapyIxekizumabTreatment OutcomeReal-worldItalyQuality of LifeSecukinumabUstekinumabPublic aspects of medicineRA1-1270Settore MED/35 - MALATTIE CUTANEE E VENEREEbusinessHumanmedicine.drugBMC Health Services Research
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Brachyodonty and hypsodontyin some Palaeogene Eurasiatic Lagomorphs

1977

Abstract Palaeogene Eurasiatic lagomorphs show more or less different degrees and kinds of brachiodonty and hypsodonty in the cheek teeth. No fully brachyodont lagomorphs are known up to the present. The probably Paleocene Mimolagus from Western Kansu shows the less advanced stage against partial hypsodonty in the upper cheek teeth. Partial hypsodonty is more advanced in the late Eocene Mongolian genera Shamolagus, Gobiolagus and Lushilagus. Roots, however, are still well developed in the cheek teeth. Some recent discoveries from earlier Oligocene sites in France and Germany seem to represent a comparable degree of hypsodonty. The Asiatic Oligocene Desmatolagus is partiallyhypsodont with ro…

Root formationPaleontologyLineage (genetic)TaxonSpace and Planetary ScienceCheek teethVallesianEurasiatic languagesHypsodontPaleontologyPaleogeneGeologyGeobios
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Cost-Efficient On-Chip Routing Implementations for CMP and MPSoC Systems

2011

[EN] The high-performance computing domain is enriching with the inclusion of networks-on-chip (NoCs) as a key component of many-core (CMPs or MPSoCs) architectures. NoCs face the communication scalability challenge while meeting tight power, area, and latency constraints. Designers must address new challenges that were not present before. Defective components, the enhancement of application-level parallelism, or power-aware techniques may break topology regularity, thus, efficient routing becomes a challenge. This paper presents universal logic-based distributed routing (uLBDR), an efficient logic-based mechanism that adapts to any irregular topology derived from 2-D meshes, instead of usi…

RouterComputer scienceRouting tableDistributed computing02 engineering and technologyMPSoCNetwork topology01 natural sciencesNetworks-on-chip0103 physical sciences0202 electrical engineering electronic engineering information engineeringElectrical and Electronic EngineeringRouting010302 applied physicsStatic routingbusiness.industryComputer Graphics and Computer-Aided Design020202 computer hardware & architectureFault-toleranceARQUITECTURA Y TECNOLOGIA DE COMPUTADORESNetwork on a chip13. Climate actionLogic designEmbedded systemScalabilityMultipath routingbusinessSoftwareIEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
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Decreased SAPK/JNK signalling affects cytokine release and STAT3 activation in psoriatic fibroblasts.

2015

STAT3 Transcription FactorMAP Kinase Signaling Systemmedicine.medical_treatmentDermatologyBiochemistryp38 Mitogen-Activated Protein KinasesPsoriasismedicineSapk jnkHumansPsoriasisPhosphorylationSTAT3Molecular BiologyStat3 activationMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3biologyChemistryInterleukin-6Tumor Necrosis Factor-alphaInterleukin-8JNK Mitogen-Activated Protein KinasesTranscription Factor RelAFibroblastsmedicine.diseaseSignallingCytokineCase-Control StudiesCancer researchbiology.proteinPhosphorylationTumor necrosis factor alphaExperimental dermatology
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