Search results for "Pandemics."

showing 10 items of 483 documents

Reduction of hospitalizations for myocardial infarction in Italy in the COVID-19 era

2020

Abstract Aims To evaluate the impact of the COVID-19 pandemic on patient admissions to Italian cardiac care units (CCUs). Methods and Results We conducted a multicentre, observational, nationwide survey to collect data on admissions for acute myocardial infarction (AMI) at Italian CCUs throughout a 1 week period during the COVID-19 outbreak, compared with the equivalent week in 2019. We observed a 48.4% reduction in admissions for AMI compared with the equivalent week in 2019 (P < 0.001). The reduction was significant for both ST-segment elevation myocardial infarction [STEMI; 26.5%, 95% confidence interval (CI) 21.7–32.3; P = 0.009] and non-STEMI (NSTEMI; 65.1%, 95% CI 60.3–70.3; P …

MaleMyocardial Infarction030204 cardiovascular system & hematologySettore MED/110302 clinical medicineAcute myocardial infarction Cardiac care units STEMI Aged Aged 80 and over COVID-19 Female Hospitalization Humans Italy Male Middle Aged SARS-CoV-2 Betacoronavirus Coronavirus Infections Myocardial Infarction Pandemics Pneumonia ViralCase fatality rate80 and overMedicine030212 general & internal medicineMyocardial infarctionViralAged 80 and overAcute myocardial infarction; Cardiac care units; COVID-19; SARS-CoV2; STEMI; Aged; Aged 80 and over; Female; Hospitalization; Humans; Italy; Male; Middle Aged; Betacoronavirus; Coronavirus Infections; Myocardial Infarction; Pandemics; Pneumonia ViralMiddle AgedHospitalizationItalyFemaleCardiology and Cardiovascular MedicineCoronavirus InfectionsHumanmedicine.medical_specialtyPneumonia ViralFast Track Clinical ResearchCardiac care unitsAcute myocardial infarctionSTEMI03 medical and health sciencesBetacoronavirusCardiac care unitHumansAcute myocardial infarction; COVID-19; Cardiac care units; SARS-CoV2; STEMIcardiovascular diseasesPandemicsAgedBetacoronaviruPandemicbusiness.industryCoronavirus InfectionSARS-CoV-2COVID-19Pneumoniamedicine.diseaseacute myocardial infarction; cardiac care units; COVID-19; SARS-CoV2; STEMIConfidence intervalRelative riskEmergency medicineSettore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARESARS-CoV2Myocardial infarction complicationsObservational studyMyocardial infarction diagnosisbusinessComplication
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Point of view of the Italians pediatric scientific societies about the pediatric care during the COVID-19 lockdown: What has changed and future prosp…

2020

Abstract Background The coronavirus disease 2019 (COVID-19) is currently rare in children and they seem to have a milder disease course and better prognosis than adults. However, SARS-Cov-2 pandemic has indirectly caused problems in pediatric medical assistance. In view of this we wanted to draw a picture of what happened during health emergency and analyze future prospects for restarting. Methods We involved the Italian pediatric scientific societies institutionally collected in the Italian Federation of Associations and Scientific Societies of the Pediatric Area (FIARPED); We sent a questionnaire to all scientific societies about the pediatric care activity during the COVID-19 emergency a…

MaleOutcome AssessmentPediatricsPatient Care PlanningSurveys and QuestionnairesPandemicOutcome Assessment Health CareAmbulatory CareMedicineViralChildChildrenSocieties MedicalPediatricEmergency Servicelcsh:RJ1-570children; COVID-19; pediatric assistance; telemedicineSettore MED/38TelemedicineHospitalizationOutpatient visitsItalySettore MED/38 - PEDIATRIA GENERALE E SPECIALISTICAQuarantineContinuity of careFemalePediatric careCoronavirus InfectionsEmergency Service HospitalHumanAdultmedicine.medical_specialtyTelemedicineCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pneumonia ViralDisease courseHospitalMedicalHumansPandemicsInfection ControlPediatric assistancePandemicbusiness.industryCoronavirus InfectionCOVID-19lcsh:PediatricsPneumoniaHealth CareFamily medicineChildren; COVID-19; Pediatric assistance; Telemedicine; Adult; Ambulatory Care; Child; Coronavirus Infections; Delivery of Health Care; Emergency Service Hospital; Female; Hospitalization; Humans; Infection Control; Italy; Male; Outcome Assessment Health Care; Pandemics; Patient Care Planning; Pediatrics; Pneumonia Viral; Quarantine; Societies Medical; Telemedicine; Surveys and QuestionnairesbusinessSocietiesDelivery of Health Care
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Patterns of liver injury in COVID-19 - a German case series.

2020

BACKGROUND: Reports of liver injury in patients with novel coronavirus disease 2019 (COVID-19) are emerging from China and the USA. A wide variety of liver function test abnormalities and few cases of severe liver failure have been reported. No data on the hepatic phenotype from Europe are available at current. METHODS: We report a case series of 44 consecutive patients hospitalized for COVID-19 in Germany. RESULTS: At the time of admission, aspartate aminotransferase greater than the upper limit of normal was present in 70%, while alanine aminotransferase was elevated in 15.8%. Markers of cholestatic liver injury were altered only in a minority of patients. During hospitalization, 31% and …

MalePathologyGerman0302 clinical medicineCOVID-19 TestingLiver Function TestsGermanyMedicineElectronic Health RecordsYoung adultLiver injuryAged 80 and overmedicine.diagnostic_testbiologyGastroenterologyAlanine TransaminaseMiddle AgedOncologyLiver030220 oncology & carcinogenesislanguage030211 gastroenterology & hepatologyFemaleChemical and Drug Induced Liver InjuryCoronavirus InfectionsAdultmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Pneumonia ViralAntiviral Agents03 medical and health sciencesBetacoronavirusYoung AdultInternal medicineHumansAspartate AminotransferasesPandemicsAgedRetrospective Studiesbusiness.industryClinical Laboratory TechniquesSARS-CoV-2COVID-19Retrospective cohort studyOriginal ArticlesHepatologyLiver Failure Acutemedicine.diseaselanguage.human_languageCOVID-19 Drug TreatmentAlanine transaminasebiology.proteinbusinessLiver function testsBiomarkersUnited European gastroenterology journal
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Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid-19

2020

Abstract: BackgroundProgressive respiratory failure is the primary cause of death in the coronavirus disease 2019 (Covid-19) pandemic. Despite widespread interest in the pathophysiology of the disease, relatively little is known about the associated morphologic and molecular changes in the peripheral lung of patients who die from Covid-19. MethodsWe examined 7 lungs obtained during autopsy from patients who died from Covid-19 and compared them with 7 lungs obtained during autopsy from patients who died from acute respiratory distress syndrome (ARDS) secondary to influenza A(H1N1) infection and 10 age-matched, uninfected control lungs. The lungs were studied with the use of seven-color immun…

MalePathologymedicine.medical_specialtyAngiogenesisPneumonia ViralAutopsy030204 cardiovascular system & hematologyNeovascularizationBetacoronavirus03 medical and health sciencesInfluenza A Virus H1N1 Subtype0302 clinical medicineInfluenza HumanmedicineHumans030212 general & internal medicineLungPandemicsAgedCause of deathAged 80 and overRespiratory Distress SyndromeNeovascularization PathologicSARS-CoV-2business.industryCOVID-19ThrombosisGeneral MedicineMiddle Agedmedicine.diseaseThrombosisPathophysiology3. Good healthPneumoniaFemaleAutopsyEndothelium VascularHuman medicinemedicine.symptomCoronavirus InfectionsRespiratory InsufficiencybusinessHuman PathologyThe New England journal of medicine
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Multicentre Italian study of SARS-CoV-2 infection in children and adolescents, preliminary data as at 10 April 2020

2020

Data on features of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children and adolescents are scarce. We report preliminary results of an Italian multicentre study comprising 168 laboratory-confirmed paediatric cases (median: 2.3 years, range: 1 day–17.7 years, 55.9% males), of which 67.9% were hospitalised and 19.6% had comorbidities. Fever was the most common symptom, gastrointestinal manifestations were frequent; two children required intensive care, five had seizures, 49 received experimental treatments and all recovered.

MalePediatricsEpidemiologyProtease InhibitorComorbiditymedicine.disease_causeClinical Laboratory TechniqueSevere Acute Respiratory SyndromeDisease OutbreaksFeces0302 clinical medicineSettore MED/38 - Pediatria Generale E SpecialisticaCOVID-19 TestingRetrospective StudiePandemic030212 general & internal medicineViralChildCoronavirusPediatricDisease OutbreakCoinfectionHospitals PediatricSettore MED/38HospitalsDiarrheaTreatment OutcomeSARS-CoV-2 infection; children; covid-19; hydroxychloroquine; pneumonia; Adolescent; Antiviral Agents; Betacoronavirus; COVID-19; COVID-19 Testing; Child; Child Preschool; Chronic Disease; Clinical Laboratory Techniques; Coinfection; Comorbidity; Coronavirus; Coronavirus Infections; Diarrhea; Disease Outbreaks; Feces; Female; Fever; Hospitals Pediatric; Humans; Immunocompromised Host; Infant; Infant Newborn; Italy; Male; Noninvasive Ventilation; Pandemics; Pneumonia Viral; Protease Inhibitors; Retrospective Studies; SARS-CoV-2; Severe Acute Respiratory Syndrome; Treatment OutcomeItalyChild PreschoolCoinfectionFemalemedicine.symptomCoronavirus InfectionsRapid CommunicationHumanDiarrheamedicine.medical_specialtyCOVID-19; ItalyhydroxychloroquineAdolescentFeverCoronaviruPneumonia ViralAntiviral Agents03 medical and health sciencesBetacoronavirusImmunocompromised Hostchildren030225 pediatricsVirologyIntensive caremedicineHumanspneumoniaProtease InhibitorsPreschoolPandemicsRetrospective StudiesAntiviral Agentchildren; covid-19; hydroxychloroquine; pneumonia; SARS-CoV-2 infection; Adolescent; Antiviral Agents; Betacoronavirus; Child; Child Preschool; Chronic Disease; Clinical Laboratory Techniques; Coinfection; Comorbidity; Coronavirus; Coronavirus Infections; Diarrhea; Disease Outbreaks; Feces; Female; Fever; Hospitals Pediatric; Humans; Immunocompromised Host; Infant; Infant Newborn; Italy; Male; Noninvasive Ventilation; Pandemics; Pneumonia Viral; Protease Inhibitors; Retrospective Studies; Severe Acute Respiratory Syndrome; Treatment OutcomeNoninvasive VentilationBetacoronaviruPandemicbusiness.industryClinical Laboratory TechniquesCoronavirus InfectionSARS-CoV-2pneumonia.SARS-CoV-2 infectionPublic Health Environmental and Occupational HealthInfant NewbornCOVID-19InfantRetrospective cohort studymedicine.diseaseNewbornComorbidityCoronavirusPneumoniaChronic DiseaseFecebusiness
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A 7-Year-Old Boy and a 14-Year-Old Girl Initially Diagnosed with Toxic Shock Syndrome and Tested Positive for SARS-CoV-2 Infection, Supporting a Diag…

2021

Case series Patients: Male, 7-year-old • Female, 14-year-old Final Diagnosis: Multisystem inflammatory syndrome in children (MIS-C) Symptoms: Muscular weakness • shock Medication: — Clinical Procedure: — Specialty: Critical Care Medicine • Infectious Diseases • Pediatrics and Neonatology • Rheumatology Objective: Unusual clinical course Background: Multisystem inflammatory syndrome in children (MIS-C) has recently been described in children infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This report describes 2 children with MIS-C who were initially diagnosed with toxic shock syndrome but who tested positive for SARS-CoV-2 infection on reverse transcription-polym…

MalePediatricsmedicine.medical_specialtyCOVID-19 Related Immunoglobulins Intravenous Mucocutaneous Lymph Node Syndrome Pediatric Multisystem Inflammatory Disease Adolescent COVID-19 Testing Child Female Humans Male Pandemics SARS-CoV-2 Systemic Inflammatory Response Syndrome COVID-19 Shock SepticAdolescentMucocutaneous Lymph Node SyndromeTachypneaPericardial effusionCOVID-19 TestingOliguriamedicineHumansPediatric Multisystem Inflammatory Disease COVID-19 RelatedChildPandemicsbusiness.industrySARS-CoV-2Toxic shock syndromeImmunoglobulins IntravenousCOVID-19General MedicineArticlesmedicine.diseaseShock SepticSystemic Inflammatory Response SyndromeSystemic inflammatory response syndromePneumoniaMethylprednisoloneMacrophage activation syndromeFemalemedicine.symptombusinessmedicine.drugThe American Journal of Case Reports
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Death by SARS-CoV 2: a Romanian COVID-19 multi-centre comorbidity study

2020

AbstractEvidence regarding the relation between SARS-CoV-2 mortality and the underlying medical condition is scarce. We conducted an observational, retrospective study based on Romanian official data about location, age, gender and comorbidities for COVID-19 fatalities. Our findings indicate that males, hypertension, diabetes, obesity and chronic kidney disease were most frequent in the COVID-19 fatalities, that the burden of disease was low, and that the prognosis for 1-year survival probability was high in the sample. Evidence shows that age-dependent pairs of comorbidities could be a negative prognosis factor for the severity of disease for the SARS-CoV 2 infection.

MalePediatricsmedicine.medical_specialtyScienceDiseasesComorbidityDisease030204 cardiovascular system & hematologyCOVID-19 ; Medical research ; Diseases ; Risk factorsAged Aged 80 and over COVID-19 Comorbidity Diabetes Mellitus Ethnicity Female Humans Hypertension Male Middle Aged Obesity Pandemics Risk Factors Romania SARS-CoV-2Article03 medical and health sciencesMedical research0302 clinical medicineDiabetes mellitusDiabetes MellitusEthnicitymedicineHumansObesity030212 general & internal medicinePandemicsAgedAged 80 and overMultidisciplinaryRomaniaSARS-CoV-2business.industryQRCOVID-19Retrospective cohort studyMiddle Agedmedicine.diseaseComorbidityObesityClinical trialRisk factorsHypertensionMedicineFemaleObservational studybusinessKidney disease
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SARS-CoV-2 infection associated with micturition syncope: Our experience with 4 case reports.

2020

Abstract Rationale: Syncope is described as the loss of consciousness and postural muscle tone with a short duration and fast onset. Micturition syncope can be caused by abnormal vasovagal response or by the dysfunction of the blood pressure regulating mechanism, which occurs before, during, or immediately after urination. Patient concerns: We present 4 cases of COVID-19 hospitalized in the Department of Infectious Diseases of the Academic Emergency Hospital Sibiu, Romania, cases that presented micturition syncope. Diagnoses: During hospitalization, patients confirmed with SARS-Cov-2 infection using real time reverse transcriptase-polymerase chain reaction (RT-PCR) assay, presented micturit…

MalePediatricsmedicine.medical_specialtymedia_common.quotation_subjectPneumonia ViralMicturition syncopeUrinationSyncope03 medical and health sciencesMuscle toneBetacoronavirus0302 clinical medicinemedicineAdrenal insufficiencyHumanscase report030212 general & internal medicineClinical Case Reportmicturition syncopePandemicsmedia_commonAgedbiologybusiness.industryRomaniaSARS-CoV-24900Syncope (genus)COVID-19General MedicineMiddle Agedmedicine.diseasebiology.organism_classificationPulmonary hypertensionPneumoniaBlood pressuremedicine.anatomical_structure030220 oncology & carcinogenesisFemalebusinessCoronavirus InfectionsResearch ArticleMedicine
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COVID-19 infection: comparing the knowledge, attitude and practices in a sample of nursing students.

2020

Background: SARS-CoV-2 infection is a global health problem that is primarily detected in Italy with progressive increase in cases and deaths. To facilitate the management of the pandemic in Italy, it is essential to understand the level of attention on COVID-19. The aim of the study was to evaluate the knowledge, attitude and practices towards SARS-CoV-2 among the nursing students of University of Palermo during the rapid rise period of the COVID-19 pandemic. Methods: The current study was a cross-sectional study. On-line questionnaires were used for the collection of the data by providing a survey in all nursing students. The questionnaire consisted of two parts: demographics and Knowledg…

MalePracticeOriginal Article: Nursing Students' PopulationAttitude of Health PersonnelCOVID-19University studentsYoung AdultCross-Sectional StudiesKnowledgeItalyAttitudeSurveys and QuestionnairesHumansFemaleStudents NursingClinical CompetencePandemicsKnowledge Attitude Practice COVID-19 Italy University studentsActa bio-medica : Atenei Parmensis
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Depression, Anxiety, and Lifestyle Among Essential Workers: A Web Survey From Brazil and Spain During the COVID-19 Pandemic

2020

Background Essential workers have been shown to present a higher prevalence of positive screenings for anxiety and depression during the COVID-19 pandemic. Individuals from countries with socioeconomic inequalities may be at increased risk for mental health disorders. Objective We aimed to assess the prevalence and predictors of depression, anxiety, and their comorbidity among essential workers in Brazil and Spain during the COVID-19 pandemic. Methods A web survey was conducted between April and May 2020 in both countries. The main outcome was a positive screening for depression only, anxiety only, or both. Lifestyle was measured using a lifestyle multidimensional scale adapted for the COV…

MalePsychological interventionAnxiety0302 clinical medicineSyndemicOdds RatioPrevalence030212 general & internal medicineAnsiedadeDepression (differential diagnoses)PandemiasDepressionlcsh:Public aspects of medicineEspanhaMiddle AgedanxietyMental Healthdepressionlcsh:R858-859.7AnxietyFemaleDepressãomedicine.symptomCoronavirus InfectionsBrazilAdultEmploymentlifestylePneumonia ViralHealth Informaticslcsh:Computer applications to medicine. Medical informaticsEstilo de vida03 medical and health sciencesEnvironmental healthmedicineHumansSocial determinants of healthLife StylePandemicsOriginal Paperbusiness.industryBrasilCOVID-19lcsh:RA1-1270Odds ratiomedicine.diseaseComorbidityMental healthHealth SurveysSocioeconomic FactorsSpainSelf Reportbusiness030217 neurology & neurosurgery
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