Search results for "Parenteral"

The effect of Betanin parenteral pretreatment on Jejunal and pulmonary tissue histological architecture and inflammatory response after Jejunal ische…

2019

Intestinal ischemic-reperfusion (IR) injury has detrimental effects on both local and distant organs in the body. Betanin is known for its antioxidant properties, and it is found mostly in vegetables. Therefore, the aim of the present study was to test the hypothesis that betanin administration prior intestinal IR, may be beneficial in protecting jejunal mucosa and lung parenchyma against IR damage. Male specific pathogen-free Charles River Wistar rats were used (n = 42). Betanin (50 mg/kg) was administered intraperitoneally 30 min before ischemia of the superior mesenteric artery lasting 1 h, followed by 1, 4 and 24 h of reperfusion. Immunohistochemical as well as histomorphometrical analy…

IN TEMA DI SINDROME DA INTESTINO CORTO: Dati preliminari da una casistica nazionale multicentrica

2002

La Sindrome da Intestico Corto (SIC) è la più frequente causa di insufficienza intestinale in età pediatrica. Allo scpo di conoscere al meglio il decorso, il trattamento e l'outcome di questi pazienti gli Autori hanno iniziato uno Studio retrospettivo nazionale sulla Sindrome da Intestino Corto e in questa sede vengono riportati i primi dati preliminari della ricerca.

Cerebral toxicity of penicillins in relation to their hydrophobic character

1975

The neurotoxic effects of ticarcillin, methicillin, phenthicillin, oxacillin, cloxacillin and dicloxacillin were studied in the conscious rabbit. During and after intravenous administration of 1.2 and 2.4 g/kg, resp., over 50 min the blood concentrations of the drugs were determined and the neurotoxicity assessed by continuous recording of the electroencephalogram. The hydrophobia of the penicillins was characterized by determination of their partition coefficients between isobutanol and buffer solution pH 7.4. The penicillins showed quite different neurotoxic properties. A close correlation (r = 0.928) was found between the neurotoxic potency of the penicillins and their partition coeffici…

Evolución de la resistencia transmitida y adquirida a fármacos antirretrovirales en pacientes infectados con VIH-1

2018

Introducción: La adquisición y transmisión de resistencia amenaza el éxito del tratamiento antirretroviral. En este estudio evaluamos el comportamiento epidemiológico de las mutaciones de resistencia (MR) a fármacos antirretrovirales del VIH-1 según factores de riesgo y clínicos específicos. Metodología: Este es un estudio retrospectivo observacional de series transversales acumuladas, realizado en la Unidad de Enfermedades Infecciosas de un hospital universitario en España (CHGUV) entre los años 2003 y 2014. Nuestro objetivo fue estimar la evolución de la frecuencia anual de MR a fármacos antirretrovirales en el genoma de la proteasa y transcriptasa inversa del VIH-1 durante el periodo de …

Características sociales y clínicas de un grupo de madres infectadas por VIH en Valencia: influencia de la drogadicción parenteral

2000

Resumen Objetivo Al principio de conocerse la infeccion por el virus de la inmunodeficiencia humana (VIH), la causa mas importante de su transmision en las mujeres occidentales fue el consumo de drogas por via parenteral. El objetivo de nuestro trabajo consistio en describir las principales caracteristicas sociales y clinicas de un grupo de madres seropositivas, y en analizar su relacion potencial con el uso intravenoso de drogas. Metodos Realizamos un estudio observacional prospectivo con 220 mujeres infectadas por VIH que presentaban la particularidad de haber dado a luz ninos con riesgo de infeccion. Se incluyeron todas las madres reclutadas en la Unidad VIH de un hospital de Valencia qu…

Correction of the unfavourable effects of vasopressin by nitroglycerin infusion

1982

Nitroglycerin was administered with vasopressin to prevent adverse effects. Vasopressin 0.25U . 70 kg-1 min-1 was infused intravenously in four dogs for 40 minutes, when a venous infusion of nitroglycerin 1.2 micrograms . kg-1 . min-1 was added for 20 minutes. Nitroglycerin 1.2 micrograms . kg-1 . min-1 alone was infused intravenously in another four dogs for 40 minutes. The venous blood pressures (mesenteric and central) and arterial pressures (mesenteric and femoral), the electrocardiogram and arterio-venous difference were recorded. Nitroglycerin was shown to annul the unfavourable effects of vasopressin without altering its efficacy upon portal pressure.

Vitamin A in parenteral nutrition: uptake and distribution of retinyl esters after intravenous application.

1989

Short-term parenteral application of vitamin A was examined in rats. Retinyl margarinate, which is chemically similar to physiological retinyl esters, was used in vitamin A-depleted rats to study uptake, distribution, and storage of retinyl esters in tissues. Vitamin A-depleted and Vitamin A-sufficient rats were infused with a micellar suspension of retinyl margarinate for 7 h and then killed at different times. Retinyl margarinate was directly taken up by all tissues examined. It appears that infusion of retinyl esters in micellar form provides a direct way to supply vitamin A to peripheral, vitamin A-dependent tissues. Therefore, a short-term infusion of retinyl esters with an emulsifier …

Summary of Discussion on the Theme: “Biochemical, Physiological, and Pathobiochemical Basis for Parenteral Nutrition”

1976

Auswirkungen parenteraler Glycerinzufuhr auf die Glycerokinase-Aktivität und den Adenosintriphosphatspiegel in der Niere von Ratten

1975

Dauerinfusionen mit Glycerin an Ratten fuhren bei Dosierungen oberhalb der durchschnittlichen maximalen Umsatzkapazitat (0,74 g.kg−1.h−1) zu Veranderungen an den Nieren in Form einer Gewichtszunahme bei gleichzeitiger Proteinverarmung und eines Aktivitatsverlustes an Glycerokinase bei deren gleichzeitigem Auftreten im Harn. Bei Dosierungen von 0,6 g.kg−1.h−1 und mehr kommt es zu einem ATP-Abfall in den Nieren. Im Gegensatz dazu sind Veranderungen in der Leber uneinheitlicb und in ahnlicher Form nur bei Dosierungsraten oberhalb der maximalen Umsatzkapazitat zu finden. Die auftretenden Veranderungen werden im Zusammenhang biokinetischer Daten und des Begriffs der osmotischen Nephrose diskutie…

Tema 17_Cas clínic_Nutrició artificial

2023

El document forma part dels materials docents programats mitjançant l'ajut del Servei de Política Lingüística de la Universitat de València. Es tracta de material docent de l’assignatura endocrinologia i nutrició II del Grau de Medicina. S’inclou el cas clínic comentat corresponent al tema 17 de l’assignatura. Es tracta d’un pacient amb malnutrició. Es desenvolupa l'etiologia, el diagnòstic, el diagnòstic diferencial i el tractament. This is teaching material for the endocrinology and nutrition II subject of the Degree in Medicine. The commented clinical case corresponding to topic 17 of the subject is included. This is a patient with malnutrition. Etiology, diagnosis, differential diagnosi…