Search results for "Percept"

AAV-Mediated Clarin-1 Expression in the Mouse Retina: Implications for USH3A Gene Therapy

2015

Usher syndrome type III (USH3A) is an autosomal recessive disorder caused by mutations in clarin-1 (CLRN1) gene, leading to progressive retinal degeneration and sensorineural deafness. Efforts to develop therapies for preventing photoreceptor cell loss are hampered by the lack of a retinal phenotype in the existing USH3 mouse models and by conflicting reports regarding the endogenous retinal localization of clarin-1, a transmembrane protein of unknown function. In this study, we used an AAV-based approach to express CLRN1 in the mouse retina in order to determine the pattern of its subcellular localization in different cell types. We found that all major classes of retinal cells express AAV…

Resultados de un programa de educación postural, con una intervención gamificada vs intervención tradicional

2021

[Resumen] La metodología de enseñanza adoptada por el profesorado puede influir en los niveles de participación y aprendizaje del alumnado. El objetivo principal de este estudio fue comparar el efecto de dos programas de intervención de educación postural en función de la metodología utilizada. Un total de 36 estudiantes (19 niñas y 17 niños) de 1º de Educación Secundaria Obligatoria participaron en el estudio. En el primer programa de intervención se aplicó una metodología gamificada, mientras que en el segundo se empleó una metodología tradicional. Ambos programas de intervención se llevaron a cabo a lo largo de 6 sesiones. Se analizaron los contenidos teóricos a través de dos cuestionari…

On the interpretation of optical illusions.

1973

If excited by stimuli adjacent in space and time, the optical system frequently perceives illusions in the form of apparent movements. These effects may be attributed to the dynamic properties of the retinal nerve nets. On the basis of a specific psychophysical experiment the mechanism underlying the generation of optical illusions is interpreted by the methods of systems theory and its use in systems analysis is discussed. It is shown that for the perception of apparent movements the transit times of the signals in the dendrites are particularly important.

Wavelength dependence of visual acuity in goldfish.

2003

Visual acuity was measured in a two-choice training experiment with food reward. Four goldfish were trained to select a homogeneously illuminated testfield when a high-contrast grating (transparency) was shown for comparison at the second testfield. Measurements were performed for white and monochromatic testfield illuminations in the light adapted state. Fourteen wavelengths between 404 nm and 683 nm were tested. For each wavelength (and white light) the testfield intensity was determined for which spatial resolution was highest. Between 446 nm and 683 nm maximal values of 2.0 cycles/deg (corresponding to a visual acuity of 15' of arc) were found. At 404 nm and in the ultraviolet resolutio…

Small field motion detection in goldfish is red-green color blind and mediated by the M-cone type

2007

Large field motion detection in goldfish, measured in the optomotor response, is based on the L-cone type, and is therefore color-blind (Schaerer & Neumeyer, 1996). In experiments using a two-choice training procedure, we investigated now whether the same holds for the detection of a small moving object (size: 8 mm diameter; velocity: 7 cm/s). In initial experiments, we found that goldfish did not discriminate between a moving and a stationary stimulus, obviously not taking attention to the cue “moving.” Therefore, random dot patterns were used in which the stimulus was visible only when moving. Using black and white random dot patterns with variable contrast between 0.2 and 1, we found…

Mathematical description of the stimuli to the lateral line system of fish derived from a three-dimensional flow field analysis

1992

The spatial distributions of the stimuli to the lateral line system of a fish moving alongside or above a plane surface are derived mathematically. The derivation was done from the analysis of the three-dimensional potential flow field on the surface of fish with bodies of circular cross-section with different shapes.

Mirror, Mirror on the Wall

2014

Our man stands with his face turned towards bygone times. He must spin around to catch a glimpse of the new days waiting to rise. The tornithologist has also arrived at the very essence of his own being, the point of embarkation, from which he can set off in search of the roots of each present moment. For the Torni, being a tower involves a twin-layered perceptual dimension. The height of the tower allows views to far-off places. From the top the gaze of an observer can pick out distant landscapes. Rising into the heavens also means standing out from one’s surroundings and this makes it impossible for a tower to conceal itself. In other words, it is gazed from and gazed upon. Even though th…

Fourier analysis of the stimuli for pattern-induced flicker colors.

1992

Pattern-induced flicker colors (PIFCs) were observed and color matched in rotating discs from which higher-harmonic Fourier components in the square-wave temporal luminance functions of a conventional black-and-white Benham disc had been removed. Since both reddish-brown and blue PIFCs were visible with purely sinusoidal stimuli they cannot result from differences in temporal stimulus shape or pattern and do not provide evidence for a temporal coding theory of color. Green PIFCs differed in that they did require the presence of additional harmonics. In a second experiment the luminance means upon which the sinusoidal PIFC stimuli were imposed were varied. The results show that color is dete…

2013

The motion energy sensor has been shown to account for a wide range of physiological and psychophysical results in motion detection and discrimination studies. It has become established as the standard computational model for retinal movement sensing in the human visual system. Adaptation effects have been extensively studied in the psychophysical literature on motion perception, and play a crucial role in theoretical debates, but the current implementation of the energy sensor does not provide directly for modelling adaptation-induced changes in output. We describe an extension of the model to incorporate changes in output due to adaptation. The extended model first computes a space-time r…

Red-green flicker resolution as a function of heterochromatic luminous modulation.

1993

Critical fusion frequencies have been evaluated in heterochromatic red-green flicker as a function of red-green luminous modulation defined by mL = (R-G)/(R+G)%, at five different mean luminance levels, two test sizes (2 degrees and 5 degrees) and square wave stimuli. The extreme values mL = +/- 100 correspond to ordinary light-dark flicker (red or green); mL = 0 corresponds to pure chromatic flicker, and any other values correspond to simultaneous luminous and chromatic flicker. To implement the stimuli we have developed a new stimuli generator (AVICO, colour vision analyser) using bicolour LEDs as the light source and electronic control of the luminances and frequencies. The results for a…