Search results for "Pharynx"

showing 10 items of 82 documents

A new method for the placement of brachytherapy probes in paranasal sinus and nasopharynx neoplasms

1999

Abstract Purpose: In afterloading therapy, the exact placement of the applicator is crucial for the result of radiotherapy. A deviation of few millimeters from the target leads to a significant reduction of radiation energy to the tumor. Methods and Materials: We present a new method using a computer-assisted device for three-dimensional placing of afterloading probes based on CT scans that allows for the exact placement. Results: Target points have been reached with an accuracy of 0.6 mm. Since 1991 we have used this technique for 24 clinical applications in 11 patients with recurrent neoplasms in the region of the paranasal sinuses and nasopharynx for palliative treatment. Conclusions: Th…

AdultCancer Researchmedicine.medical_specialtyPalliative treatmentNasopharynx Neoplasmsmedicine.medical_treatmentBrachytherapyBrachytherapyHumansMedicineRadiology Nuclear Medicine and imagingSinus (anatomy)AgedRadiationbusiness.industryComputer aidCarcinomaNasopharyngeal NeoplasmsEquipment DesignMiddle AgedRadiotherapy Computer-AssistedRadiation therapymedicine.anatomical_structureParanasal sinusesOncologyCarcinoma Squamous CellRadiologyNeoplasm Recurrence LocalTomography X-Ray ComputedbusinessParanasal Sinus NeoplasmsInternational Journal of Radiation Oncology*Biology*Physics
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The external frame function in the control of pitch, register, and singing mode: Radiographic observations of a female singer

1999

Summary This study investigates pitch control, register, and singing mode related movements of the laryngo-pharyngeal structures by radiographic methods. One trained female singer served as the subject. The results show that singing voice production involves complex movements in the laryngeal structures. Pitch related increase in the thyro-arytenoid distance (vocal fold length) is nonlinear, slowing down as pitch rises. Similar observations have been made earlier. At the highest pitches, a shortening of the distance can be seen, suggesting the use of alternative pitch control mechanisms. The various observations made support the existence of three registers in this trained female singing vo…

AdultLarynxVoice QualitySpeech recognitionSpeech and HearingMode (music)PhonationPitch controlPhoneticsotorhinolaryngologic diseasesmedicineHumansControl (linguistics)Hyoid BoneFunction (mathematics)LPN and LVNhumanitiesRadiographymedicine.anatomical_structureOtorhinolaryngologyRegister (music)Thyroid CartilagePharynxFemaleLarynxSingingPsychologypsychological phenomena and processesArytenoid CartilageRelative pitchJournal of Voice
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Differences in incidence and survival of oral cavity and pharyngeal cancers between Germany and the United States depend on the HPV-association of th…

2017

Abstract Introduction The epidemiology of squamous cell oral cavity and pharyngeal cancers (OCPC) has changed rapidly during the last years, possibly due to an increase of human papilloma virus (HPV) positive tumors and successes in tobacco prevention. Here, we compare incidence and survival of OCPC by HPV-relation of the site in Germany and the United States (US). Materials and methods Age-standardized and age-specific incidence and 5-year relative survival was estimated using data from population-based cancer registries in Germany and the US Surveillance Epidemiology and End Results (SEER) 13 database. Incidence was estimated for each year between 1999 and 2013. Relative survival for 2002…

AdultMaleCancer Researchmedicine.medical_specialtyAdolescentPopulationHealthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]03 medical and health sciencesYoung AdultAll institutes and research themes of the Radboud University Medical Center0302 clinical medicinePharyngeal cancerGermanyEpidemiologySurveillance Epidemiology and End ResultsMedicineHumans030212 general & internal medicineeducationAgededucation.field_of_studyRelative survivalbusiness.industryIncidence (epidemiology)IncidencePharynxPapillomavirus InfectionsCancerPharyngeal NeoplasmsMiddle Agedmedicine.diseaseSurvival AnalysisUnited StatesSurgeryTumor Virus Infectionsmedicine.anatomical_structureOncology030220 oncology & carcinogenesisFemaleMouth NeoplasmsOral SurgerybusinessDemography
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High constant incidence rates of second primary cancers of the head and neck: a pooled analysis of 13 cancer registries

2010

Scanty data are available on the incidence (i.e., the absolute risk) of second cancers of the head and neck (HN) and its pattern with age. We investigated this issue using data from a multicentric study of 13 population-based cancer registries from Europe, Canada, Australia and Singapore for the years 1943-2000. A total of 99,257 patients had a first primary HN cancer (15,985 tongue, 22,378 mouth, 20,758 pharyngeal, and 40,190 laryngeal cancer), contributing to 489,855 person-years of follow-up. 1294 of the patients (1.3%) were diagnosed with second HN cancers (342 tongue, 345 mouth, 418 pharynx, and 189 larynx). Male incidence rates of first HN cancer steeply increased from 0.68/100,000 at…

AdultMaleLarynxOncologyCancer Researchmedicine.medical_specialtyPopulationArticlehead and neckTongueInternal medicineEpidemiologymedicineHumanscancerpooled analysiRegistrieseducationAgedAged 80 and overGynecologyeducation.field_of_studybusiness.industryIncidence (epidemiology)second neoplasmsHead and neck cancerPharynxCancerNeoplasms Second PrimaryMiddle Agedmedicine.diseasesecond primaryAdult ; Aged ; Aged 80 and over ; Female ; Head and Neck Neoplasms/epidemiology* ; Humans ; Incidence ; Male ; Middle Aged ; Neoplasms Second Primary/epidemiology*; Registriesmedicine.anatomical_structureOncologyageHead and Neck Neoplasmscancer registriesincidenceFemalehead and neck cancerHigh constant incidence ratebusiness
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Rupture of supra-aortic neck arteries due to lesions caused by tracheal tubes

1984

Haemorrhages from the common carotid or innominate artery caused by tracheal tubes are rare but dramatic complications of head and neck surgery. Patients with metal tracheostomy cannulas or patients in the phase of wound healing after radical tumour resections of the pharynx and larynx run a greater risk. Following extensive tumour resections and radiation of the upper respiratory and digestive tracts in 680 patients, acute bleeding of the larger neck arteries occurred in 18 patients. In four of these cases, fistulae developed in the innominate or common carotid artery. These ruptures were caused by both plastic and metal tracheal tubes.

AdultMaleLarynxmedicine.medical_specialtyHemorrhagePostoperative Complicationsmedicine.arteryIntubation IntratrachealmedicineHumansCommon carotid arteryRespiratory systemLaryngeal NeoplasmsBrachiocephalic TrunkAgedRupturebusiness.industryPharynxGeneral MedicineMiddle AgedSurgerymedicine.anatomical_structureOtorhinolaryngologyHead and neck surgeryDigestive tractCarotid Artery InjuriesbusinessAortic neckArteryThe Journal of Laryngology & Otology
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A comparative study of the pharyngeal airway space, measured with cone beam computed tomography, between patients with different craniofacial morphol…

2014

Abstract Purpose The present study aims to determine any existing association between airway dimensions, measured with cone beam computed tomography (CBCT), and the different patient craniofacial morphologies. Material and methods Sixty CBCT (Dental Picasso Master 3D) images, from patients treated at the Orthodontics Master at Valencia University were selected. The program InVivoDental 5.1 was used to visualize sections, analyze three-dimensional images, and perform airway measurements in the three planes of the space. Intra- and interobserver error methods were recorded. After that, measurements at three different levels of the airway (upper, medium, lower) were taken, in both the anteropo…

AdultMalePalate HardCone beam computed tomographyAdolescentClass iiiMalocclusion Angle Class IMandibleMalocclusion Angle Class IIYoung AdultImaging Three-DimensionalImage Processing Computer-AssistedMedicineHumansCraniofacialChildSkull Basebusiness.industryHyoid BoneReproducibility of ResultsVertical DimensionAnatomyrespiratory systemCone-Beam Computed TomographyCross-Sectional StudiesMalocclusion Angle Class IIIOtorhinolaryngologyPharynxSurgeryFemaleOral SurgeryAnatomic LandmarksPalate SoftbusinessAirwayMalocclusionJournal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
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Cytotoxic and genotoxic effects of electronic cigarette liquids on human mucosal tissue cultures of the oropharynx

2016

The popularity of electronic cigarettes (ECs) is rapidly growing and ECs are claimed to be an uncritically regarded alternative to conventional cigarettes. The mucosal tissue of the upper aerodigestive tract (UADT) is the first contact organ for xenobiotics such as liquids of ECs. The aim of this study is to investigate the bimolecular effects of e-liquids on human pharyngeal tissue cultures to evaluate whether e-liquids and their components present a risk factor for head and neck squamous cell carcinoma. Fresh tissue samples of healthy oropharyngeal mucosa were assembled into mucosal tissue cultures. Two fruit-flavored liquids (FLs), one tobacco-flavored liquid (TL) (all containing nicotin…

AdultMalePathologymedicine.medical_specialtyOropharyngeal TissueDNA damageCell SurvivalHealth Toxicology and MutagenesisOropharynxElectronic Nicotine Delivery SystemsToxicologyPathology and Forensic Medicine03 medical and health sciencesTissue cultureYoung Adult0302 clinical medicineFresh TissueRisk FactorsGermanyMedicineHumansCarcinogenMucous Membranebusiness.industryCytotoxinsSquamous Cell Carcinoma of Head and NeckGeneral Medicinemedicine.diseaseHead and neck squamous-cell carcinoma3. Good health030228 respiratory systemHead and Neck NeoplasmsToxicityCancer researchCarcinoma Squamous CellDNA fragmentationFemalebusiness030217 neurology & neurosurgeryDNA DamageMutagens
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Obesity and craniofacial variables in subjects with obstructive sleep apnea syndrome: comparisons of cephalometric values

2007

AbstractBackgroundThe aim of this paper was to determine the most common craniofacial changes in patients suffering Obstructive Sleep Apnea Syndrome (OSAS) with regards to the degree of obesity. Accordingly, cephalometric data reported in the literature was searched and analyzed.MethodsAfter a careful analysis of the literature from 1990 to 2006, 5 papers with similar procedural criteria were selected. Inclusion criteria were: recruitment of Caucasian patients with an apnea-hypopnea index (AHI) >10 as grouped in non-obese (Body Mass Index – [BMI] < 30)vs. obese (BMI ≥ 30).ResultsA low position of the hyoid bone was present in both groups. In non-obese patients, an increased value of t…

AdultMalePediatricsmedicine.medical_specialtylcsh:Specialties of internal medicineCephalometryPolysomnographyClinical NeurologyDentistryReviewPolysomnographySensitivity and SpecificitySeverity of Illness IndexBody Mass IndexTonguelcsh:RC581-951Reference ValuesRisk FactorsSeverity of illnessmedicineHumansObesityCraniofacialGeneral DentistryAgedSleep Apnea Obstructivemedicine.diagnostic_testDentistry(all)business.industryIncidenceSleep apneaMiddle AgedCraniometrymedicine.diseaseObesityrespiratory tract diseasesObstructive sleep apneaJawOtorhinolaryngologyCase-Control StudiesPharynxFemaleNeurology (clinical)Palate SoftbusinessBody mass indexHead & Face Medicine
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Symptoms and complications of pertussis in adults

1995

There is increasing evidence that pertussis occurs frequently in adults, but there is limited information on the clinical course of this disease beyond childhood. A household contact study on the efficacy of an acellular pertussis vaccine was used to study the symptoms of pertussis in adults. Among 257 patients with pertussis identified in 121 families during a two-year period in one study center with a low whole-cell pertussis-vaccine uptake, 79 (30.7%) were adults, aged 19–83 years (mean age: 36 years) with a 1:1.8 male to female ratio. Ninety-one percent of the adults suffered from coughing (mean duration: 54 days), and in 80% this cough lasted ≥ 21 days. Whoops were rare (8%), whereas c…

AdultMaleSleep Wake DisordersMicrobiology (medical)Pediatricsmedicine.medical_specialtyVomitingWhooping CoughPainPoison controlEnzyme-Linked Immunosorbent AssaySweatingSneezingBordetella pertussisNasopharynxmedicineHumansProspective StudiesChildProspective cohort studyWhooping coughAgedAged 80 and overPertussis VaccineHoarsenessbusiness.industryHeadacheGeneral MedicineMiddle Agedmedicine.diseaseAntibodies BacterialAirway ObstructionInfectious DiseasesCoughAnesthesiaVomitingPertussis vaccineFemaleHeadachesmedicine.symptomChokingComplicationbusinessmedicine.drugInfection
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Effects of cold atmospheric plasma (CAP) on bacteria and mucosa of the upper aerodigestive tract.

2019

Abstract Objective Ear, nose and throat infections are among the most common reasons for absence from work. They are usually caused by various bacteria like Haemophilus influenzae, Staphylococcus aureus, Streptococcus pneumoniae and Streptococcus pyogenes. Cold atmospheric plasma (CAP) can effectively eliminate even multi-resistant bacteria and has no cytotoxic or mutagenic effects on the mucosa when applied for less than 60 s. Aim of the study was to evaluate the effects of CAP on common ENT bacteria and on the mucosa of the upper aerodigestive tract. Methods The bactericidal effects of CAP against the bacteria most commonly causing ENT infections were investigated using the colony-forming…

AdultMaleStaphylococcus aureusNecrosisPlasma GasesCell SurvivalStreptococcus pyogenesColony Count MicrobialOropharynxRespiratory Mucosamedicine.disease_causeMicrobiologyHaemophilus influenzae03 medical and health sciencesNecrosisYoung Adult0302 clinical medicineOrgan Culture TechniquesStreptococcus pneumoniaeotorhinolaryngologic diseasesmedicineHumansOtitisViability assay030223 otorhinolaryngologyRespiratory Tract InfectionsNoseRhinitisbiologybusiness.industryPharyngitisGeneral MedicineMiddle Agedbiology.organism_classificationHaemophilus influenzae3. Good healthmedicine.anatomical_structureStreptococcus pneumoniaeOtorhinolaryngologyStaphylococcus aureus030220 oncology & carcinogenesisStreptococcus pyogenesSurgeryFemalemedicine.symptombusinessBacteriaAuris, nasus, larynx
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