Search results for "Physics::Medical Physics"
showing 10 items of 188 documents
Analysis of human skin hyper-spectral images by non-negative matrix factorization
2011
International audience; This article presents the use of Non-negative Matrix Factorization, a blind source separation algorithm, for the decomposition of human skin absorption spectra in its main pigments: melanin and hemoglobin. The evaluated spectra come from a Hyper-Spectral Image, which is the result of the processing of a Multi-Spectral Image by a neural network-based algorithm. The implemented source separation algorithm is based on a multiplicative coeffi cient upload. The goal is to represent a given spectrum as the weighted sum of two spectral components. The resulting weighted coefficients are used to quantify melanin and hemoglobin content in the given spectra. Results present a …
Statistical methods for determining components non-liniarities, from thermoluminescent devices
2016
Thermoluminescent (TLD) dosimeters enjoy wide usage due to low cost and simplicity of use. They have however large errors at high doses in mixed-radiation fields, where non-linear effects occur. Algorithms based on the Akaike criterion [1] are presented for determining the maximal (physically meaningful) polynomial order with which the non-linearities are modeled. This depends on the number of points existing on a curve and on the points' errors.
Integration of multifunctions with closed convex values in arbitrary Banach spaces
2018
Integral properties of multifunctions with closed convex values are studied. In this more general framework not all the tools and the technique used for weakly compact convex valued multifunctions work. We pay particular attention to the "positive multifunctions". Among them an investigation of multifunctions determined by vector-valued functions is presented. Finally, decomposition results are obtained for scalarly and gauge-defined integrals of multifunctions and a full description of McShane integrability in terms of Henstock and Pettis integrability is given.
Anomalous water dynamics in brain: a combined diffusion magnetic resonance imaging and neutron scattering investigation
2019
International audience; Water diffusion is an optimal tool for investigating the architecture of brain tissue on which modern medical diagnostic imaging techniques rely. However, intrinsic tissue heterogeneity causes systematic deviations from pure free-water diffusion behaviour. To date, numerous theoretical and empirical approaches have been proposed to explain the non-Gaussian profile of this process. The aim of this work is to shed light on the physics piloting water diffusion in brain tissue at the micrometre-to-atomic scale. Combined diffusion magnetic resonance imaging and first pioneering neutron scattering experiments on bovine brain tissue have been performed in order to probe dif…
Hyperpolarized 1H long lived states originating from parahydrogen accessed by rf irradiation
2013
Hyperpolarization has found many applications in Nuclear Magnetic Resonance (NMR) and Magnetic Resonance Imaging (MRI). However, its usage is still limited to the observation of relatively fast processes because of its short lifetimes. This issue can be circumvented by storing the hyperpolarization in a slowly relaxing singlet state. Symmetrical molecules hyperpolarized by Parahydrogen Induced Hyperpolarization (PHIP) provide a straightforward access to hyperpolarized singlet states because the initial parahydrogen singlet state is preserved at almost any magnetic field strength. In these systems, which show a remarkably long 1H singlet state lifetime of several minutes, the conversion of t…
Non-uniform multivariate embedding to assess the information transfer in cardiovascular and cardiorespiratory variability series
2012
The complexity of the short-term cardiovascular control prompts for the introduction of multivariate (MV) nonlinear time series analysis methods to assess directional interactions reflecting the underlying regulatory mechanisms. This study introduces a new approach for the detection of nonlinear Granger causality in MV time series, based on embedding the series by a sequential, non-uniform procedure, and on estimating the information flow from one series to another by means of the corrected conditional entropy. The approach is validated on short realizations of linear stochastic and nonlinear deterministic processes, and then evaluated on heart period, systolic arterial pressure and respira…
Vector Autoregressive Fractionally Integrated Models to Assess Multiscale Complexity in Cardiovascular and Respiratory Time Series
2020
Cardiovascular variability is the result of the activity of several physiological control mechanisms, which involve different variables and operate across multiple time scales encompassing short term dynamics and long range correlations. This study presents a new approach to assess the multiscale complexity of multivariate time series, based on linear parametric models incorporating autoregressive coefficients and fractional integration. The approach extends to the multivariate case recent works introducing a linear parametric representation of multiscale entropy, and is exploited to assess the complexity of cardiovascular and respiratory time series in healthy subjects studied during postu…
Radiation Tolerance Tests of Small-Sized CsI(Tl) Scintillators Coupled to Photodiodes
2009
Radiation tolerance of small-sized CsI (Tl) crystals coupled to silicon photodiodes was studied by using protons. Irradiations up to the fluence of 1012 protons/cm2 were used. Degradation of light output by less than 5% was achieved.
Dosimetry for electron Intra-Operative RadioTherapy: Comparison of output factors obtained through alanine/EPR pellets, ionization chamber and Monte …
2015
Abstract In this work a comparison between the response of alanine and Markus ionization chamber was carried out for measurements of the output factors (OF) of electron beams produced by a linear accelerator used for Intra-Operative Radiation Therapy (IORT). Output factors (OF) for conventional high-energy electron beams are normally measured using ionization chamber according to international dosimetry protocols. However, the electron beams used in IORT have characteristics of dose per pulse, energy spectrum and angular distribution quite different from beams usually used in external radiotherapy, so the direct application of international dosimetry protocols may introduce additional uncer…
Hardening and long-range stress formation in lithium fluoride induced by energetic ions
2003
Abstract LiF crystals were irradiated with Au, Pb, Bi and S ions in the energy range 400–2300 MeV and studied by means of Vickers microindentation. Remarkable hardening effects are observed which depend on the applied fluence and ion species, and correlate with the ion energy loss along the ion path. Structural investigations reveal irradiation-induced stress extending deep into the adjacent non-irradiated crystal and leading to the formation of dislocations. X-ray diffraction measurements of the irradiated crystals show a decrease of the lattice constant indicating the presence of internal stress.