Search results for "Plant Bark"

showing 10 items of 32 documents

Tannins from Hamamelis virginiana Bark Extract: Characterization and Improvement of the Antiviral Efficacy against Influenza A Virus and Human Papill…

2014

Antiviral activity has been demonstrated for different tannin-rich plant extracts. Since tannins of different classes and molecular weights are often found together in plant extracts and may differ in their antiviral activity, we have compared the effect against influenza A virus (IAV) of Hamamelis virginiana L. bark extract, fractions enriched in tannins of different molecular weights and individual tannins of defined structures, including pseudotannins. We demonstrate antiviral activity of the bark extract against different IAV strains, including the recently emerged H7N9, and show for the first time that a tannin-rich extract inhibits human papillomavirus (HPV) type 16 infection. As the …

PhytochemistryViral DiseasesPhytopharmacologylcsh:MedicineEpigallocatechin gallateMadin Darby Canine Kidney Cellschemistry.chemical_compoundMolecular Cell BiologyDrug DiscoveryTanninGallic acidlcsh:Sciencechemistry.chemical_classificationHuman papillomavirus 16MultidisciplinarybiologyChemistryInfectious DiseasesBiochemistryProanthocyanidinInfluenza A virusvisual_artPlant Barkvisual_art.visual_art_mediumMedicineBarkResearch Articlemedicine.drugDrugs and DevicesHuman Papillomavirus InfectionDrug Research and DevelopmentSexually Transmitted DiseasesHamamelisAntiviral AgentsDogsComplementary and Alternative MedicineInfluenza HumanTannic acidmedicineAnimalsHumansBiologyPlant Extractslcsh:RPapillomavirus InfectionsHamamelis virginianaInfluenzachemistrybiology.proteinlcsh:QTanninsNeuraminidasePLoS ONE
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Assessment of the possibility of using deciduous tree bark as a biomonitor of heavy metal pollution of atmospheric aerosol

2019

The aim of the research was to assess the possibility to use deciduous tree bark in the biomonitoring of urban areas. The tree bark taken from various deciduous tree species growing in the Opole Province (south-western Poland) was used for the research. The bark was collected from tree trunks in the period of June 2–26, 2017. Concentrations of the heavy metals were determined in the barks by flame atomic absorption spectrometry (FAAS). On the basis of the research, it was determined that type of tree, distance from pollution source, elevation off the ground and the side of trunk from which bark was sampled all influence the research results. A comparison of the values of coefficient of vari…

PollutionHealth Toxicology and Mutagenesismedia_common.quotation_subjectAtomic absorption spectrometry010501 environmental sciencesOpole Province01 natural sciencesTreesBarkQuercus roburFagus sylvaticaMetals HeavyEnvironmental ChemistryDeciduous treesBetula0105 earth and related environmental sciencesmedia_commonAerosolsAir PollutantsbiologyForestryGeneral Medicinebiology.organism_classificationPollutionDeciduousBetula pendulavisual_artBiomonitoringTrace elementPlant Barkvisual_art.visual_art_mediumEnvironmental scienceBarkPolandEnvironmental PollutionBioindicatorEnvironmental MonitoringWoody plantEnvironmental Science and Pollution Research
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Absorption of polycyclic aromatic hydrocarbons by pinus bark: analytical method and use for environmental pollution monitoring in the Palermo area (S…

2007

Abstract In the light of using biomaterial as pollutants sorbents for the environmental biomonitoring, we report here the results of the absorption of polycyclic aromatic hydrocarbons (PAHs) by pine bark. Quantitative analysis of 19 different polycyclic aromatic compounds was performed, after Soxhlet extraction in dichloromethane, by means GC–MS technique. Pinus was chosen due to its wide distribution in the Mediterranean area. The passive absorption of PAH by pine bark in the metropolitan areas allowed us to evaluate the air quality of Palermo. The obtained results showed a very high range of PAHs concentrations, from 33 μg/kg (bark dry weight), as ΣPAHs, at the control site to 1015 μg/kg …

PollutionSurface Propertiesmedia_common.quotation_subjectEnvironmental pollutionBiochemistryPalermoGas Chromatography-Mass SpectrometryAbsorptionBarkPinus BioaccumulatorBiomonitoringSettore CHIM/01 - Chimica AnaliticaCitiesPolycyclic Aromatic HydrocarbonsSicilyAir quality indexGeneral Environmental Sciencemedia_commonPollutantchemistry.chemical_classificationAir PollutantsPersistent organic pollutantGC/MSPAHPinusHydrocarbonchemistryvisual_artEnvironmental chemistryAir qualityPlant Barkvisual_art.visual_art_mediumEnvironmental scienceBarkEnvironmental Monitoring
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Arboreasides A−E, Triterpene Saponins from the Bark of Cussonia arborea

2009

Five new triterpene saponins, arboreasides A-E (1-5), and two known saponins, ciwujianoside C(3) and 23-hydroxyursolic acid 28-O-alpha-L-rhamnopyranosyl-(1--4)-beta-D-glucopyranosyl-(1--6)-beta-D-glucopyranosyl ester, were isolated from the bark of Cussonia arborea. The structures were established using extensive 1D and 2D NMR spectroscopic analyses and mass spectrometry.

SaponinPharmaceutical SciencePharmacognosyAnalytical ChemistryTriterpeneDrug DiscoveryBotanyCameroonAraliaceaeNuclear Magnetic Resonance BiomolecularPharmacologychemistry.chemical_classificationMolecular StructurebiologyOrganic ChemistryGlycosideSaponinsbiology.organism_classificationTriterpenesTerpenoidComplementary and alternative medicinechemistryvisual_artPlant Barkvisual_art.visual_art_mediumMolecular MedicineAraliaceaeBarkCussonia arboreaJournal of Natural Products
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New triterpenoid estersaponins from the root barks of Pittosporum verticillatum subsp. verticillatum and evaluation of cytotoxicities

2013

The phytochemical investigation of the root barks of Pittosporum verticillatum Bojer subsp. verticillatum led to the isolation of three new triterpene saponins, 3-O-[β-D-glucopyranosyl-(1→2)]-[α-L-arabinopyranosyl-(1→3)]-[α-L-arabinofuranosyl-(1→4)]-β-D-glucuronopyranosyl-21-O-(2-acetoxy-2-methylbutanoyl)-R1-barrigenol (1), 3-O-[β-D-glucopyranosyl-(1→2)]-[α-L-arabinopyranosyl-(1→3)]-[α-L-arabinofuranosyl-(1→4)]-β-D-glucuronopyranosyl-21-O-(2-acetoxy-2-methylbutanoyl)-28-O-acetyl-R1-barrigenol (2), 3-O-[β-D-glucopyranosyl-(1→2)]-[α-L-arabinopyranosyl-(1→3)]-[α-L-arabinofuranosyl-(1→4)]-β-D-glucuronopyranosyl-21-O-β,β-dimethylacryloyl-22-O-angeloyl-R1-barrigenol (3), and one known saponin sen…

Senaciapittoside BStereochemistrySaponinPlant RootsCell LineTerpeneTriterpenoidTriterpeneCell Line TumorNeoplasmsDrug DiscoveryAnimalsHumansRosalesPharmacologychemistry.chemical_classificationMolecular StructurebiologyPlant ExtractsGeneral MedicineSaponinsPittosporumbiology.organism_classificationTriterpenesRatschemistryPhytochemicalPlant BarkHuman cancerFitoterapia
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Terpenoid glycosides from the root's barks of Eriocoelum microspermum Radlk. ex Engl.

2018

Abstract Eight undescribed triterpenoid saponins together with a known one, and two undescribed sesquiterpene glycosides were isolated from root's barks of Eriocoelum microspermum. Their structures were elucidated by spectroscopic methods including 1D and 2D experiments in combinaison with mass spectrometry as 3-O-α-L-rhamnopyranosyl-(1 → 3)-[α-L-rhamnopyranosyl-(1 → 2)]-α-L-arabinopyranosylhederagenin, 3-O-α-L-rhamnopyranosyl-(1 → 3)-[β-D-glucopyranosyl-(1 → 3)-α-L-rhamnopyranosyl-(1 → 2)]-α-L-arabinopyranosylhederagenin, 3-O-α-L-rhamnopyranosyl-(1 → 3)-[β-D-xylopyranosyl-(1 → 3)-α-L-rhamnopyranosyl-(1 → 2)]-α-L-arabinopyranosylhederagenin, 3-O-α-L-rhamnopyranosyl-(1 → 4)-[α-L-rhamnopyrano…

StereochemistryChemical structurePlant ScienceHorticultureSesquiterpenePlant Roots01 natural sciencesBiochemistrychemistry.chemical_compoundSapindaceaeTriterpenoidCarbohydrate ConformationEriocoelum microspermumGlycosidesMolecular Biologychemistry.chemical_classificationTerpenes010405 organic chemistryChemistrySapindoideaeGlycosideGeneral MedicineTerpenoid0104 chemical sciences010404 medicinal & biomolecular chemistryChemotaxonomyPlant BarkPhytochemistry
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Steroidal saponins from two species of Dracaena.

2010

Four new steroidal saponins (1-4) were isolated from the stem and bark of two species of Dracaena: deistelianosides A and B (1 and 2) from D. deisteliana and arboreasaponins A and B (3 and 4) from D. arborea. Six known saponins and one known sapogenin were also isolated. The structures of 1-4 were established as diosgenin 3-O-[3-O-sulfate-alpha-l-rhamnopyranosyl-(1-->4)]-beta-d-glucopyranoside (1), 1-O-beta-d-xylopyranosyl-(1-->2)-[alpha-l-rhamnopyranosyl-(1-->3)]-beta-d-fucopyranosyl(23S,24S)-spirosta-5,25(27)-diene-1beta,3beta,23alpha,24alpha-tetrol 24-O-alpha-l-arabinopyranoside (2), pennogenin-3-O-alpha-l-rhamnopyranosyl-(1-->2)-[alpha-l-rhamnopyranosyl-(1-->3)]-[6-O-acetyl]-beta-d-gluc…

StereochemistryChemical structureSaponinPharmaceutical ScienceSapogeninPharmacognosyAnalytical Chemistrychemistry.chemical_compoundDrug DiscoveryHumansCameroonNuclear Magnetic Resonance BiomolecularDracaenaPharmacologychemistry.chemical_classificationPlants MedicinalbiologyMolecular StructurePlant StemsChemistryOrganic ChemistryGlycosideStereoisomerismDiosgeninSaponinsbiology.organism_classificationHCT116 CellsComplementary and alternative medicinevisual_artvisual_art.visual_art_mediumPlant BarkMolecular MedicineBarkSteroidsDracaenaHT29 CellsJournal of natural products
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Furoquinolines and dihydrooxazole alkaloids with cytotoxic activity from the stem bark of Araliopsis soyauxii.

2018

Abstract Two new furoquinoline alkaloids, maculine B (1) and kokusaginine B (2) and one new dihydrooxazole alkaloid, veprisazole (3), along with four known compounds namely, N13-methyl-3-methoxyrutaecarpine (4), flindersiamine (5), skimmianine (6) and tilianin (7) were isolated from the methanol extract of the stem bark of Araliopsis soyauxii Engl. by various chromatographic methods. Their structures were determined using spectrometry and spectroscopic techniques including NMR and MS. The cytotoxicity of the new compounds compared to that of doxorubicin, the reference anticancer compound, was determined on a panel of nine cancer cell lines including sensitive and drug resistant phenotypes. …

StereochemistryPhytochemicalsDioxoles01 natural sciencesAlkaloidsCell Line TumorDrug DiscoverymedicineCytotoxic T cellHumansDoxorubicinCameroonGlycosidesMedicinal plantsCytotoxicityFuransIC50RutaceaePharmacologyFlavonoidsMolecular Structure010405 organic chemistryChemistryAlkaloidGeneral MedicineAntineoplastic Agents PhytogenicDrug Resistance Multiple0104 chemical sciences010404 medicinal & biomolecular chemistryCell cultureDrug Resistance Neoplasmvisual_artvisual_art.visual_art_mediumPlant BarkQuinolinesBarkmedicine.drugFitoterapia
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Rotenoids, Flavonoids, and Chalcones from the Root Bark of Millettia usaramensis.

2015

Five new compounds, 4-O-geranylisoliquiritigenin (1), 12-dihydrousararotenoid B (2), 12-dihydrousararotenoid C (3), 4'-O-geranyl-7-hydroxyflavanone (4), and 4'-O-geranyl-7-hydroxydihydroflavanol (5), along with 12 known natural products (6-17) were isolated from the CH2Cl2/MeOH (1:1) extract of the root bark of Millettia usaramensis ssp. usaramensis by chromatographic separation. The purified metabolites were identified by NMR spectroscopic and mass spectrometric analyses, whereas their absolute configurations were established on the basis of chiroptical data and in some cases also by X-ray crystallography. The crude extract was moderately active (IC50 = 11.63 μg/mL) against the ER-negative…

StereochemistryPlasmodium falciparumMolecular ConformationPharmaceutical Scienceroot barkCrystallography X-Ray01 natural sciencesMillettiaAnalytical ChemistryMillettia usaramensischemistry.chemical_compoundAntimalarialsChalconesDrug DiscoveryPlant BarkHumansta116IC50Nuclear Magnetic Resonance Biomolecularta317metabolitesPharmacologyFlavonoidsChromatographyNatural productbiologyMolecular Structure010405 organic chemistryChemistryPlant ExtractsOrganic ChemistryPlasmodium falciparumChloroquinebiology.organism_classification0104 chemical sciencesMillettia010404 medicinal & biomolecular chemistryChromatographic separationHEK293 CellsComplementary and alternative medicinevisual_artFlavanonesvisual_art.visual_art_mediumPlant BarkMolecular MedicineBarkrotenoidsJournal of natural products
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Cytotoxicity of the crude extract and constituents of the bark of Fagara tessmannii towards multi-factorial drug resistant cancer cells.

2019

Abstract Ethnopharmacological relevance Fagara tessmannii Engl. is an African medicinal plant used in Cameroonian traditional medicine to treat various types of cancers. Aim of the study This work was designed to determine the cytotoxicity of the crude extract (FTB), fractions (FTBa-d) and compounds isolated from the bark of Fagara tessmannii, namely lupeol (1), fagaramide (2), zanthoxyline (3), hesperidin (4), nitidine chloride (5), fagaridine chloride (6), and β-sitosterol-3-O-β-D-glucopyranoside (7). The study was extended to the mode of induction of apoptosis by FTB, compounds 5 and 6. Materials and methods The resazurin reduction assay was used to evaluate the cytotoxicity of samples. …

ZanthoxylumApoptosisFlow cytometry03 medical and health scienceschemistry.chemical_compoundHesperidinInhibitory Concentration 500302 clinical medicineCell Line TumorNeoplasmsDrug DiscoverymedicineHumansCytotoxicity030304 developmental biologyLupeolPharmacologychemistry.chemical_classificationMembrane Potential Mitochondrial0303 health sciencesReactive oxygen speciesmedicine.diagnostic_testPlant ExtractsCell CycleCell cycleMolecular biologyAntineoplastic Agents PhytogenicchemistryApoptosisDoxorubicinDrug Resistance Neoplasm030220 oncology & carcinogenesisCancer cellPlant BarkReactive Oxygen SpeciesJournal of ethnopharmacology
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